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Employment (3)

Tel Aviv University: Tel Aviv, IL

Assistant Professor (Chemistry)
Employment
Source: Self-asserted source
Muhammad Jbara

Tel Aviv University: Tel Aviv, IL

2022-01-01 to present (School Of Chemistry)
Employment
Source: check_circle
Tel Aviv University

Massachusetts Institute of Technology: Cambridge, MA, US

2019-07 to 2021-12 | Postdoctoral Fellow (Chemistry )
Employment
Source: Self-asserted source
Muhammad Jbara

Education and qualifications (1)

Technion Israel Institute of Technology: Haifa, Haifa, IL

2015 to 2019 | PhD (Schulich Faculty of Chemistry)
Education
Source: Self-asserted source
Muhammad Jbara

Works (49)

Abiotic Transcription Factors by Strategic Insertion of Non-Proteinogenic Amino Acids

2025-03-13 | Preprint
DOI: 10.26434/chemrxiv-2025-rdbs7
Contributors: Omer Harel; Ferran Nadal-Bufi; Raj Nithun; Yumi Minyi Yao; Ariel Afek; Marc Vendrell; Muhammad Jbara
Source: check_circle
Crossref

Unprecedented Photoinduced‐Electron‐Transfer Probe with a Turn‐ON Chemiluminescence Mode‐of‐Action

Angewandte Chemie
2025-02-03 | Journal article
DOI: 10.1002/ange.202417924
Contributors: Maya David; Sara Gutkin; Raj V. Nithun; Muhammad Jbara; Doron Shabat
Source: check_circle
Crossref

Unprecedented Photoinduced‐Electron‐Transfer Probe with a Turn‐ON Chemiluminescence Mode‐of‐Action

Angewandte Chemie International Edition
2025-02-03 | Journal article
DOI: 10.1002/anie.202417924
Contributors: Maya David; Sara Gutkin; Raj V. Nithun; Muhammad Jbara; Doron Shabat
Source: check_circle
Crossref

Late-Stage Minimal Labeling of Peptides and Proteins for Real-Time Imaging of Cellular Trafficking

ACS Central Science
2025-01-22 | Journal article
DOI: 10.1021/acscentsci.4c01249
Contributors: Ferran Nadal-Bufi; Raj V. Nithun; Fabio de Moliner; Xiaoxi Lin; Shaimaa Habiballah; Muhammad Jbara; Marc Vendrell
Source: check_circle
Crossref

Late-stage Minimal Labeling of Peptides and Proteins for Real-time Imaging of Cellular Trafficking

2024-09-27 | Preprint
DOI: 10.26434/chemrxiv-2024-d7bj8
Contributors: Ferran Nadal-Bufi; Raj V. Nithun; Fabio de Moliner; Xiaoxi Lin; Shaimaa Habiballah; Muhammad Jbara; Marc Vendrell
Source: check_circle
Crossref

A Versatile Method for Site-Specific Chemical Installation of Aromatic Posttranslational Modification Analogs into Proteins

Journal of the American Chemical Society
2024-09-18 | Journal article
DOI: 10.1021/jacs.4c08416
Contributors: Xiaoxi Lin; Shaswati Mandal; Raj V. Nithun; Rajasekhar Kolla; Bouchra Bouri; Hilal A. Lashuel; Muhammad Jbara
Source: check_circle
Crossref

Unprecedented Photoinduced-Electron-Transfer Probe with a Turn-ON Chemiluminescence Mode-of-Action

2024-09-18 | Preprint
DOI: 10.26434/chemrxiv-2024-vj8f6
Contributors: Maya David; Sara Gutkin; Raj V. Nithun; Muhammad Jbara; Doron Shabat
Source: check_circle
Crossref

Site-Specific Acetylation of the Transcription Factor Protein Max Modulates Its DNA Binding Activity

ACS Central Science
2024-06-26 | Journal article
DOI: 10.1021/acscentsci.4c00686
Contributors: Raj V. Nithun; Yumi Minyi Yao; Omer Harel; Shaimaa Habiballah; Ariel Afek; Muhammad Jbara
Source: check_circle
Crossref

A Versatile Method for Site-Specific Chemical Installation of Aromatic Posttranslational Modification Analogs into Proteins

2024-06-17 | Preprint
DOI: 10.26434/chemrxiv-2024-v46r0
Contributors: Xiaoxi Lin; Shaswati Mandal; Raj V. Nithun; Rajasekhar Kolla; Bouchra Bouri; Hilal A. Lashuel; Muhammad Jbara
Source: check_circle
Crossref

Chemical Engineering of Artificial Transcription Factors by Orthogonal Palladium(II)‐Mediated S‐Arylation Reactions

Angewandte Chemie International Edition
2024-01-25 | Journal article
DOI: 10.1002/anie.202317511
Contributors: Xiaoxi Lin; Omer Harel; Muhammad Jbara
Source: check_circle
Crossref

Chemical Engineering of Artificial Transcription Factors by Orthogonal Palladium(II)‐Mediated S‐Arylation Reactions

Angewandte Chemie
2024-01-25 | Journal article
DOI: 10.1002/ange.202317511
Contributors: Xiaoxi Lin; Omer Harel; Muhammad Jbara
Source: check_circle
Crossref

Cover Picture: Deciphering the Role of the Ser‐Phosphorylation Pattern on the DNA‐Binding Activity of Max Transcription Factor Using Chemical Protein Synthesis (Angew. Chem. Int. Ed. 47/2023)

Angewandte Chemie International Edition
2023-11-20 | Journal article
DOI: 10.1002/anie.202313716
Contributors: Raj V. Nithun; Yumi Minyi Yao; Xiaoxi Lin; Shaimaa Habiballah; Ariel Afek; Muhammad Jbara
Source: check_circle
Crossref

Deciphering the Role of the Ser‐Phosphorylation Pattern on the DNA‐Binding Activity of Max Transcription Factor Using Chemical Protein Synthesis

Angewandte Chemie
2023-11-20 | Journal article
DOI: 10.1002/ange.202310913
Contributors: Raj V. Nithun; Yumi Minyi Yao; Xiaoxi Lin; Shaimaa Habiballah; Ariel Afek; Muhammad Jbara
Source: check_circle
Crossref

Deciphering the Role of the Ser‐Phosphorylation Pattern on the DNA‐Binding Activity of Max Transcription Factor Using Chemical Protein Synthesis

Angewandte Chemie International Edition
2023-11-20 | Journal article
DOI: 10.1002/anie.202310913
Contributors: Raj V. Nithun; Yumi Minyi Yao; Xiaoxi Lin; Shaimaa Habiballah; Ariel Afek; Muhammad Jbara
Source: check_circle
Crossref

Titelbild: Deciphering the Role of the Ser‐Phosphorylation Pattern on the DNA‐Binding Activity of Max Transcription Factor Using Chemical Protein Synthesis (Angew. Chem. 47/2023)

Angewandte Chemie
2023-11-20 | Journal article
DOI: 10.1002/ange.202313716
Contributors: Raj V. Nithun; Yumi Minyi Yao; Xiaoxi Lin; Shaimaa Habiballah; Ariel Afek; Muhammad Jbara
Source: check_circle
Crossref

Histone H3 serine-57 is a CHK1 substrate whose phosphorylation affects DNA repair

Nature Communications
2023-08-22 | Journal article
DOI: 10.1038/s41467-023-40843-4
Contributors: Nikolaos Parisis; Pablo D. Dans; Muhammad Jbara; Balveer Singh; Diane Schausi-Tiffoche; Diego Molina-Serrano; Isabelle Brun-Heath; Denisa Hendrychová; Suman Kumar Maity; Diana Buitrago et al.
Source: check_circle
Crossref

Enabling Peptide Ligation at Aromatic Junction Mimics via Native Chemical Ligation and Palladium-Mediated S-Arylation

Organic Letters
2023-06-30 | Journal article
DOI: 10.1021/acs.orglett.3c01652
Contributors: Xiaoxi Lin; Raj V. Nithun; Raju Samanta; Omer Harel; Muhammad Jbara
Source: check_circle
Crossref

Chemical Synthesis of Bioactive Proteins

Angewandte Chemie International Edition
2023-03-20 | Journal article
DOI: 10.1002/anie.202217716
Contributors: Omer Harel; Muhammad Jbara
Source: check_circle
Crossref

Chemical Synthesis of Bioactive Proteins

Angewandte Chemie
2023-03-20 | Journal article
DOI: 10.1002/ange.202217716
Contributors: Omer Harel; Muhammad Jbara
Source: check_circle
Crossref

Posttranslational Chemical Mutagenesis Methods to Insert Posttranslational Modifications into Recombinant Proteins

Molecules
2022-07-08 | Journal article
DOI: 10.3390/molecules27144389
Contributors: Omer Harel; Muhammad Jbara
Source: check_circle
Crossref
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Parallel Automated Flow Synthesis of Covalent Protein Complexes That Can Inhibit MYC-Driven Transcription

ACS Central Science
2021-08-25 | Journal article
DOI: 10.1021/acscentsci.1c00663
Contributors: Sebastian Pomplun; Muhammad Jbara; Carly K. Schissel; Susana Wilson Hawken; Ann Boija; Charles Li; Isaac Klein; Bradley L. Pentelute
Source: check_circle
Crossref

Engineering Bioactive Dimeric Transcription Factor Analogs via Palladium Rebound Reagents

Journal of the American Chemical Society
2021-08-04 | Journal article
DOI: 10.1021/jacs.1c05666
Contributors: Muhammad Jbara; Sebastian Pomplun; Carly K. Schissel; Susana Wilson Hawken; Ann Boija; Isaac Klein; Jacob Rodriguez; Stephen L. Buchwald; Bradley L. Pentelute
Source: check_circle
Crossref

Oligonucleotide Bioconjugation with Bifunctional Palladium Reagents

Angewandte Chemie
2021-05-17 | Journal article
DOI: 10.1002/ange.202103180
Contributors: Muhammad Jbara; Jacob Rodriguez; Heemal H. Dhanjee; Andrei Loas; Stephen L. Buchwald; Bradley L. Pentelute
Source: check_circle
Crossref

Oligonucleotide Bioconjugation with Bifunctional Palladium Reagents

Angewandte Chemie International Edition
2021-05-17 | Journal article
DOI: 10.1002/anie.202103180
Contributors: Muhammad Jbara; Jacob Rodriguez; Heemal H. Dhanjee; Andrei Loas; Stephen L. Buchwald; Bradley L. Pentelute
Source: check_circle
Crossref

De Novo Discovery of High-Affinity Peptide Binders for the SARS-CoV-2 Spike Protein

ACS Central Science
2021-01-27 | Journal article
DOI: 10.1021/acscentsci.0c01309
Contributors: Sebastian Pomplun; Muhammad Jbara; Anthony J. Quartararo; Genwei Zhang; Joseph S. Brown; Yen-Chun Lee; Xiyun Ye; Stephanie Hanna; Bradley L. Pentelute
Source: check_circle
Crossref

De NovoDiscovery of High Affinity Peptide Binders for the SARS-CoV-2 Spike Protein

2020-09-29 | Preprint
DOI: 10.1101/2020.09.29.317131
Contributors: Sebastian Pomplun; Muhammad Jbara; Anthony J. Quartararo; Genwei Zhang; Joseph S. Brown; Yen-Chun Lee; Xiyun Ye; Stephanie Hanna; Bradley L. Pentelute
Source: check_circle
Crossref

Transition metal catalyzed site-selective cysteine diversification of proteins

Pure and Applied Chemistry
2020-07-13 | Journal article
DOI: 10.1515/pac-2020-0504
Part of ISSN: 1365-3075
Part of ISSN: 0033-4545
Source: Self-asserted source
Muhammad Jbara

Examining Several Strategies for the Chemical Synthesis of Phosphorylated Histone H3 Reveals the Effectiveness of the Convergent Approach

European Journal of Organic Chemistry
2020-06-08 | Journal article
DOI: 10.1002/ejoc.201900257
Contributors: Muhammad Jbara; Suman Kumar Maity; Ashraf Brik
Source: check_circle
Crossref

Gold(I)-Mediated Decaging or Cleavage of Propargylated Peptide Bond in Aqueous Conditions for Protein Synthesis and Manipulation

Journal of the American Chemical Society
2020-05-06 | Journal article
DOI: 10.1021/jacs.9b13216
Contributors: Muhammad Jbara; Emad Eid; Ashraf Brik
Source: check_circle
Crossref

FACT and Ubp10 collaborate to modulate H2B deubiquitination and nucleosome dynamics

eLife
2019 | Journal article
DOI: 10.7554/elife.40988.001
Source: Self-asserted source
Muhammad Jbara

Semisynthesis of ubiquitinated histone H2B with a native or nonhydrolyzable linkage

Methods in Enzymology
2019 | Book chapter
DOI: 10.1016/bs.mie.2019.01.003
Part of ISBN: 9780128163597
Part of ISSN: 0076-6879
Source: Self-asserted source
Muhammad Jbara

Palladium mediated deallylation in fully aqueous conditions for native chemical ligation at aspartic and glutamic acid sites

Organic & Biomolecular Chemistry
2018 | Journal article
DOI: 10.1039/C8OB00890F
Contributors: Muhammad Jbara; Emad Eid; Ashraf Brik
Source: check_circle
Crossref

Chemical chromatin ubiquitylation

Current Opinion in Chemical Biology
2018-08 | Journal article
DOI: 10.1016/j.cbpa.2018.02.001
Part of ISSN: 1367-5931
Source: Self-asserted source
Muhammad Jbara

Palladium prompted on-demand cysteine chemistry for the synthesis of challenging and uniquely modified proteins

Nature Communications
2018-08-08 | Journal article
DOI: 10.1038/s41467-018-05628-0
Contributors: Muhammad Jbara; Shay Laps; Michael Morgan; Guy Kamnesky; Guy Mann; Cynthia Wolberger; Ashraf Brik
Source: check_circle
Crossref

Total chemical synthesis of histones and their analogs, assisted by native chemical ligation and palladium complexes

Nature Protocols
2017-11 | Journal article
DOI: 10.1038/nprot.2017.049
Part of ISSN: 1754-2189
Part of ISSN: 1750-2799
Source: Self-asserted source
Muhammad Jbara

Total chemical synthesis of methylated analogues of histone 3 revealed KDM4D as a potential regulator of H3K79me3

Bioorganic & Medicinal Chemistry
2017-09 | Journal article
DOI: 10.1016/j.bmc.2017.04.015
Part of ISSN: 0968-0896
Source: Self-asserted source
Muhammad Jbara

Palladium in der chemischen Synthese und Modifizierung von Proteinen

Angewandte Chemie
2017-08-28 | Journal article
DOI: 10.1002/ange.201702370
Contributors: Muhammad Jbara; Suman Kumar Maity; Ashraf Brik
Source: check_circle
Crossref

Palladium in the Chemical Synthesis and Modification of Proteins

Angewandte Chemie International Edition
2017-08-28 | Journal article
DOI: 10.1002/anie.201702370
Contributors: Muhammad Jbara; Suman Kumar Maity; Ashraf Brik
Source: check_circle
Crossref

Palladium-Assisted Cleavage of Peptides and Proteins Containing a Backbone with Thiazolidine Linkage

Chemistry - A European Journal
2016-10-10 | Journal article
DOI: 10.1002/chem.201603676
Part of ISSN: 0947-6539
Source: Self-asserted source
Muhammad Jbara

Efficient Palladium-Assisted One-Pot Deprotection of (Acetamidomethyl)Cysteine Following Native Chemical Ligation and/or Desulfurization To Expedite Chemical Protein Synthesis

Angewandte Chemie International Edition
2016-07-04 | Journal article
DOI: 10.1002/anie.201603169
Part of ISSN: 1433-7851
Source: Self-asserted source
Muhammad Jbara

Palladium-Assisted Removal of a Solubilizing Tag from a Cys Side Chain To Facilitate Peptide and Protein Synthesis

Organic Letters
2016-06-17 | Journal article
DOI: 10.1021/acs.orglett.6b01442
Part of ISSN: 1523-7060
Part of ISSN: 1523-7052
Source: Self-asserted source
Muhammad Jbara

Chemical and semisynthesis of modified histones

Journal of Peptide Science
2016-05 | Journal article
DOI: 10.1002/psc.2848
Part of ISSN: 1075-2617
Source: Self-asserted source
Muhammad Jbara

Expanding the chemical toolbox for the synthesis of large and uniquely modified proteins

Nature Chemistry
2016-05 | Journal article
DOI: 10.1038/nchem.2476
Part of ISSN: 1755-4330
Part of ISSN: 1755-4349
Source: Self-asserted source
Muhammad Jbara

Palladium Mediated Rapid Deprotection of N-Terminal Cysteine under Native Chemical Ligation Conditions for the Efficient Preparation of Synthetically Challenging Proteins

Journal of the American Chemical Society
2016-04-20 | Journal article
DOI: 10.1021/jacs.5b13580
Part of ISSN: 0002-7863
Part of ISSN: 1520-5126
Source: Self-asserted source
Muhammad Jbara

Chemical Synthesis of Phosphorylated Histone H2A at Tyr57 Reveals Insight into the Inhibition Mode of the SAGA Deubiquitinating Module

Angewandte Chemie International Edition
2016-04-11 | Journal article
DOI: 10.1002/anie.201600638
Part of ISSN: 1433-7851
Source: Self-asserted source
Muhammad Jbara

Convergent Versus Sequential Protein Synthesis: The Case of Ubiquitinated and Glycosylated H2B

Angewandte Chemie International Edition
2015-10-12 | Journal article
DOI: 10.1002/anie.201503309
Part of ISSN: 1433-7851
Source: Self-asserted source
Muhammad Jbara

KPC1-Mediated Ubiquitination and Proteasomal Processing of NF-κB1 p105 to p50 Restricts Tumor Growth

Cell
2015-04 | Journal article
DOI: 10.1016/j.cell.2015.03.001
Part of ISSN: 0092-8674
Source: Self-asserted source
Muhammad Jbara

Solid phase chemical ligation employing a rink amide linker for the synthesis of histone H2B protein

Chem. Commun.
2014-09-08 | Journal article
DOI: 10.1039/c4cc06499b
Part of ISSN: 1359-7345
Part of ISSN: 1364-548X
Source: Self-asserted source
Muhammad Jbara

Modifying the Vicinity of the Isopeptide Bond To Reveal Differential Behavior of Ubiquitin Chains with Interacting Proteins: Organic Chemistry Applied to Synthetic Proteins

Angewandte Chemie International Edition
2013-10-11 | Journal article
DOI: 10.1002/anie.201306118
Part of ISSN: 1433-7851
Source: Self-asserted source
Muhammad Jbara

Peer review (8 reviews for 4 publications/grants)

Review activity for Angewandte Chemie. (4)
Review activity for ChemBioChem. (1)
Review activity for Journal of the American Chemical Society. (2)
Review activity for Nature chemistry. (1)
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