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Scopus Author ID: 6602078355
Loop profile: 73998

Keywords

Trypanosoma, tsetse, saliva proteins, skin bite site, drug resistance, HAT diagnosis

Countries

Belgium

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Employment (5)

Institute of Tropical Medicine Antwerp: Antwerp, BE

2021-12-01 to present | Full professor; Head of Trypanosoma Unit (Biomedical Sciences)
Employment
Source: Self-asserted source
Jan Van Den Abbeele

Institute of Tropical Medicine Antwerp: Antwerp, BE

2016-07-01 to 2021-11-30 | Professor; Head of Veterinary Protozoology unit (Biomedical Sciences)
Employment
Source: Self-asserted source
Jan Van Den Abbeele

Institute of Tropical Medicine Antwerp: Antwerp, BE

2010-04-01 to 2016-06-30 | Associate professor; Head of Veterinary Protozoology unit (Biomedical Sciences)
Employment
Source: Self-asserted source
Jan Van Den Abbeele

Institute of Tropical Medicine Antwerp: Antwerp, BE

2002-01-01 to 2010-03-31 | Postdoctoral Researcher (Parasitology)
Employment
Source: Self-asserted source
Jan Van Den Abbeele

Université Libre de Bruxelles: Bruxelles, BE

2001-03-01 to 2001-12-31 | Postdoctoral Researcher (Molecular Parasitology)
Employment
Source: Self-asserted source
Jan Van Den Abbeele

Education and qualifications (1)

University of Antwerp: Antwerp, BE

1981-10-01 to 1985-09-30 | Master in Biological Sciences (Zoology)
Education
Source: Self-asserted source
Jan Van Den Abbeele

Works (50 of 103)

Items per page:
Page 1 of 3

Split-Cre-mediated GFP expression as a permanent marker for flagellar fusion of Trypanosoma brucei in its tsetse fly host.

mBio
2024-12-17 | Journal article
DOI: 10.1128/mbio.03375-24
PMID: 39688410
Contributors: Ruth Etzensperger; Benninger M; Pozzi B; Rehmann R; Naguleswaran A; Schumann G; Van Den Abbeele J; Isabel Roditi
Source: Self-asserted source
Jan Van Den Abbeele

The Trypanosoma brucei MISP family of invariant proteins is co-expressed with BARP as triple helical bundle structures on the surface of salivary gland forms, but is dispensable for parasite development within the tsetse vector.

PLoS pathogens
2023-03-30 | Journal article
DOI: 10.1371/journal.ppat.1011269
PMID: 36996244
PMC: PMC10089363
Contributors: Aitor Casas-Sanchez; Ramaswamy R; Perally S; LR Haines; Rose C; Aguilera-Flores M; Portillo S; Verbeelen M; Hussain S; Smithson L et al.
Source: Self-asserted source
Jan Van Den Abbeele

Heme-deficient metabolism and impaired cellular differentiation as an evolutionary trade-off for human infectivity in Trypanosoma brucei gambiense.

Nature communications
2022-11-18 | Journal article | Author
DOI: 10.1038/s41467-022-34501-4
PMID: 36400774
Contributors: Eva Horáková; Lecordier L; Cunha P; Roman Sobotka; Changmai P; Langedijk CJM; Jan Van Den Abbeele; Benoit Vanhollebeke; Julius Lukes
Source: Self-asserted source
Jan Van Den Abbeele

A multi-adenylate cyclase regulator at the flagellar tip controls African trypanosome transmission.

Nature communications
2022-09-16 | Journal article | Author
DOI: 10.1038/s41467-022-33108-z
PMID: 36114198
PMC: PMC9481589
Contributors: Sabine Bachmaier; Giacomelli G; Estefanía Calvo Alvarez; Larissa Rezende Vieira; Jan Van Den Abbeele; Aris Aristodemou; Esben Lorentzen; Matthew Gould; Brennand A; Jean-William Dupuy et al.
Source: Self-asserted source
Jan Van Den Abbeele

Targeting the tsetse-trypanosome interplay using genetically engineered Sodalis glossinidius.

PLoS pathogens
2022-03-10 | Journal article
DOI: 10.1371/journal.ppat.1010376
PMID: 35271685
PMC: PMC8939806
Source: Self-asserted source
Jan Van Den Abbeele

Prevalence of Trypanosoma and Sodalis in wild populations of tsetse flies and their impact on sterile insect technique programmes for tsetse eradication.

Scientific reports
2022-02-28 | Journal article
DOI: 10.1038/s41598-022-06699-2
PMID: 35228552
PMC: PMC8885713
Source: Self-asserted source
Jan Van Den Abbeele

Tsetse salivary glycoproteins are modified with paucimannosidic N-glycans, are recognised by C-type lectins and bind to trypanosomes.

PLoS neglected tropical diseases
2021-02-02 | Journal article
DOI: 10.1371/journal.pntd.0009071
PMID: 33529215
PMC: PMC7880456
Source: Self-asserted source
Jan Van Den Abbeele

Evaluation of the relative roles of the Tabanidae and Glossinidae in the transmission of trypanosomosis in drug resistance hotspots in Mozambique.

Parasites & vectors
2020-04-29 | Journal article
DOI: 10.1186/s13071-020-04087-1
PMID: 32349788
PMC: PMC7189697
Source: Self-asserted source
Jan Van Den Abbeele

Catalase compromises the development of the insect and mammalian stages of Trypanosoma brucei.

The FEBS journal
2019-10-29 | Journal article
DOI: 10.1111/febs.15083
PMID: 31593329
Source: Self-asserted source
Jan Van Den Abbeele

Comparative genomic analysis of six Glossina genomes, vectors of African trypanosomes.

Genome biology
2019-09-02 | Journal article
DOI: 10.1186/s13059-019-1768-2
PMID: 31477173
PMC: PMC6721284
Source: Self-asserted source
Jan Van Den Abbeele

The Tsetse Fly Displays an Attenuated Immune Response to Its Secondary Symbiont, Sodalis glossinidius.

Frontiers in Microbiology
2019-07-24 | Journal article
DOI: 10.3389/fmicb.2019.01650
PMID: 31396178
PMC: PMC6668328
Source: Self-asserted source
Jan Van Den Abbeele

Complement Receptor 1 availability on red blood cell surface modulates Plasmodium vivax invasion of human reticulocytes.

Scientific reports
2019-06-20 | Journal article
DOI: 10.1038/s41598-019-45228-6
PMID: 31221984
Source: Self-asserted source
Jan Van Den Abbeele

Innate immunity in the tsetse fly (Glossina), vector of African trypanosomes.

Developmental and comparative immunology
2019-05-07 | Journal article
DOI: 10.1016/j.dci.2019.05.003
PMID: 31075296
Source: Self-asserted source
Jan Van Den Abbeele

Aberrant use and poor quality of trypanocides: a risk for drug resistance in south western Ethiopia

BMC veterinary research
2018 | Journal article
DOI: 10.1186/s12917-017-1327-6
EID:

2-s2.0-85053311175
Contributors: Tekle, T.; Terefe, G.; Cherenet, T.; Ashenafi, H.; Akoda, K.G.; Teko-Agbo, A.; Van Den Abbeele, J.; Gari, G.; Clausen, P.-H.; Hoppenheit, A. et al.
Source: Self-asserted source
Jan Van Den Abbeele via Scopus - Elsevier

Mitonuclear genomics challenges the theory of clonality in Trypanosoma congolense: Reply to Tibayrenc and Ayala

Molecular Ecology
2018 | Journal article
DOI: 10.1111/mec.14809
EID:

2-s2.0-85053215736
Contributors: Van den Broeck, F.; Tavernier, L.J.M.; Vermeiren, L.; Dujardin, J.-C.; Van Den Abbeele, J.
Source: Self-asserted source
Jan Van Den Abbeele via Scopus - Elsevier

Neutrophils enhance early Trypanosoma brucei infection onset

Scientific Reports
2018 | Journal article
DOI: 10.1038/s41598-018-29527-y
EID:

2-s2.0-85050674147
Contributors: Caljon, G.; Mabille, D.; Stijlemans, B.; De Trez, C.; Mazzone, M.; Tacchini-Cottier, F.; Malissen, M.; A. Van Ginderachter, J.; Magez, S.; De Baetselier, P. et al.
Source: Self-asserted source
Jan Van Den Abbeele via Scopus - Elsevier

Resistance to trypanocidal drugs in cattle populations of Zambezia Province, Mozambique

Parasitology Research
2018 | Journal article
DOI: 10.1007/s00436-017-5718-1
EID:

2-s2.0-85038636043
Contributors: Mulandane, F.C.; Fafetine, J.; Van Den Abbeele, J.; Clausen, P.-H.; Hoppenheit, A.; Cecchi, G.; Oosthuizen, M.; Delespaux, V.; Neves, L.
Source: Self-asserted source
Jan Van Den Abbeele via Scopus - Elsevier

Thioester-containing proteins in the tsetse fly (Glossina) and their response to trypanosome infection

Insect Molecular Biology
2018 | Journal article
DOI: 10.1111/imb.12382
EID:

2-s2.0-85043528130
Contributors: Matetovici, I.; Van Den Abbeele, J.
Source: Self-asserted source
Jan Van Den Abbeele via Scopus - Elsevier

Combining paratransgenesis with SIT: impact of ionizing radiation on the DNA copy number of Sodalis glossinidius in tsetse flies.

BMC microbiology
2018-11-23 | Journal article
DOI: 10.1186/s12866-018-1283-8
PMID: 30470179
PMC: PMC6251162
Source: Self-asserted source
Jan Van Den Abbeele

Towards improving tsetse fly paratransgenesis: stable colonization of Glossina morsitans morsitans with genetically modified Sodalis.

BMC microbiology
2018-11-23 | Journal article
DOI: 10.1186/s12866-018-1282-9
PMID: 30470181
PMC: PMC6251102
Source: Self-asserted source
Jan Van Den Abbeele

Drug quality analysis of isometamidium chloride hydrochloride and diminazene diaceturate used for the treatment of African animal trypanosomosis in West Africa.

BMC veterinary research
2018-11-20 | Journal article
DOI: 10.1186/s12917-018-1633-7
PMID: 30458767
PMC: PMC6247674
Source: Self-asserted source
Jan Van Den Abbeele

How rational drug use reduces trypanosome infections in cattle in chemo-resistance hot-spot villages of northern Togo.

Acta tropica
2018-11-19 | Journal article
DOI: 10.1016/j.actatropica.2018.11.023
PMID: 30465741
Source: Self-asserted source
Jan Van Den Abbeele

Cattle breeding, trypanosomosis prevalence and drug resistance in Northern Togo

Veterinary Parasitology
2017 | Journal article
DOI: 10.1016/j.vetpar.2017.02.008
EID:

2-s2.0-85013271898
Contributors: Tchamdja, E.; Kulo, A.E.; Vitouley, H.S.; Batawui, K.; Bankolé, A.A.; Adomefa, K.; Cecchi, G.; Hoppenheit, A.; Clausen, P.H.; De Deken, R. et al.
Source: Self-asserted source
Jan Van Den Abbeele via Scopus - Elsevier

Chapter 12: Tsetse fly saliva proteins as biomarkers of vector exposure.

Arthropod Vector: Controller of Disease Transmission, Volume 2.
2017 | Book chapter
Part of ISBN: 978-0-12-805360-7
Source: Self-asserted source
Jan Van Den Abbeele

Chapter 8: Early immunological responses upon tsetse fly-mediated trypanosome inoculation.

Arthropod Vector: Controller of Disease Transmission, Volume 2.
2017 | Book chapter
Part of ISBN: 978-0-12-805360-7
Source: Self-asserted source
Jan Van Den Abbeele

Discovery and genomic analyses of hybridization between divergent lineages of Trypanosoma congolense, causative agent of Animal African Trypanosomiasis

Molecular Ecology
2017 | Journal article
DOI: 10.1111/mec.14271
EID:

2-s2.0-85028024829
Contributors: Tihon, E.; Imamura, H.; Dujardin, J.-C.; Van Den Abbeele, J.; Van den Broeck, F.
Source: Self-asserted source
Jan Van Den Abbeele via Scopus - Elsevier

Evidence for viable and stable triploid Trypanosoma congolense parasites

Parasites and Vectors
2017 | Journal article
DOI: 10.1186/s13071-017-2406-z
EID:

2-s2.0-85031089967
Contributors: Tihon, E.; Imamura, H.; Dujardin, J.-C.; Van Den Abbeele, J.
Source: Self-asserted source
Jan Van Den Abbeele via Scopus - Elsevier

Genomic analysis of Isometamidium Chloride resistance in Trypanosoma congolense

International Journal for Parasitology: Drugs and Drug Resistance
2017 | Journal article
DOI: 10.1016/j.ijpddr.2017.10.002
EID:

2-s2.0-85031709369
Contributors: Tihon, E.; Imamura, H.; Van den Broeck, F.; Vermeiren, L.; Dujardin, J.-C.; Van Den Abbeele, J.
Source: Self-asserted source
Jan Van Den Abbeele via Scopus - Elsevier

Human African trypanosomiasis control: Achievements and challenges

PLoS Neglected Tropical Diseases
2017 | Journal article
DOI: 10.1371/journal.pntd.0005454
EID:

2-s2.0-85019033104
Contributors: Aksoy, S.; Buscher, P.; Lehane, M.; Solano, P.; Van Den Abbeele, J.
Source: Self-asserted source
Jan Van Den Abbeele via Scopus - Elsevier

Nanobodies As tools to Understand, diagnose, and treat African trypanosomiasis

Frontiers in Immunology
2017 | Journal article
DOI: 10.3389/fimmu.2017.00724
EID:

2-s2.0-85021776062
Contributors: Stijlemans, B.; Baetselier, P.D.; Caljon, G.; Van Den Abbeele, J.; Van Ginderachter, J.A.; Magez, S.
Source: Self-asserted source
Jan Van Den Abbeele via Scopus - Elsevier

The Trypanosoma brucei TbHrg protein is a heme transporter involved in the regulation of stage-specific morphological transitions

Journal of Biological Chemistry
2017 | Journal article
DOI: 10.1074/jbc.M116.762997
EID:

2-s2.0-85018346018
Contributors: Horáková, E.; Changmai, P.; Vancová, M.; Sobotka, R.; Van Den Abbeele, J.; Vanhollebeke, B.; Lukeš, J.
Source: Self-asserted source
Jan Van Den Abbeele via Scopus - Elsevier

Characterization and pharmacological analysis of two adipokinetic hormone receptor variants of the tsetse fly, Glossina morsitans morsitans

Insect Biochemistry and Molecular Biology
2016 | Journal article
DOI: 10.1016/j.ibmb.2015.11.010
EID:

2-s2.0-84951811934
Contributors: Caers, J.; Janssen, T.; Van Rompay, L.; Broeckx, V.; Van Den Abbeele, J.; Gäde, G.; Schoofs, L.; Beets, I.
Source: Self-asserted source
Jan Van Den Abbeele via Scopus - Elsevier

Characterization of a neuropeptide F receptor in the tsetse fly, Glossina morsitans morsitans

Journal of Insect Physiology
2016 | Journal article
DOI: 10.1016/j.jinsphys.2016.09.013
EID:

2-s2.0-84988944321
Contributors: Caers, J.; Van Hiel, M.B.; Peymen, K.; Zels, S.; Van Rompay, L.; Van Den Abbeele, J.; Schoofs, L.; Beets, I.
Source: Self-asserted source
Jan Van Den Abbeele via Scopus - Elsevier

Drug quality analysis through high performance liquid chromatography of isometamidium chloride hydrochloride and diminazene diaceturate purchased from official and unofficial sources in Northern Togo

Preventive Veterinary Medicine
2016 | Journal article
DOI: 10.1016/j.prevetmed.2016.02.001
EID:

2-s2.0-84959860650
Contributors: Tchamdja, E.; Kulo, A.E.; Akoda, K.; Teko-Agbo, A.; Assoumy, A.M.; Niang, E.M.M.; Batawui, K.; Adomefa, K.; Bankolé, A.A.; Kombiagou, K. et al.
Source: Self-asserted source
Jan Van Den Abbeele via Scopus - Elsevier

Immune evasion strategies of Trypanosoma brucei within the mammalian host: Progression to pathogenicity

Frontiers in Immunology
2016 | Journal article
DOI: 10.3389/fimmu.2016.00233
EID:

2-s2.0-84977510005
Contributors: Stijlemans, B.; Caljon, G.; Van Den Abbeele, J.; Van Ginderachter, J.A.; Magez, S.; De Trez, C.
Source: Self-asserted source
Jan Van Den Abbeele via Scopus - Elsevier

MIF-Mediated Hemodilution Promotes Pathogenic Anemia in Experimental African Trypanosomosis

PLoS Pathogens
2016 | Journal article
DOI: 10.1371/journal.ppat.1005862
EID:

2-s2.0-84989856462
Contributors: Stijlemans, B.; Brys, L.; Korf, H.; Bieniasz-Krzywiec, P.; Sparkes, A.; Vansintjan, L.; Leng, L.; Vanbekbergen, N.; Mazzone, M.; Caljon, G. et al.
Source: Self-asserted source
Jan Van Den Abbeele via Scopus - Elsevier

Molecular characterization of a short neuropeptide F signaling system in the tsetse fly, Glossina morsitans morsitans

General and Comparative Endocrinology
2016 | Journal article
DOI: 10.1016/j.ygcen.2016.06.005
EID:

2-s2.0-84976254635
Contributors: Caers, J.; Peymen, K.; Van Hiel, M.B.; Van Rompay, L.; Van Den Abbeele, J.; Schoofs, L.; Beets, I.
Source: Self-asserted source
Jan Van Den Abbeele via Scopus - Elsevier

The Dermis as a Delivery Site of Trypanosoma brucei for Tsetse Flies

PLoS Pathogens
2016 | Journal article
DOI: 10.1371/journal.ppat.1005744
EID:

2-s2.0-84982924029
Contributors: Caljon, G.; Van Reet, N.; De Trez, C.; Vermeersch, M.; Pérez-Morga, D.; Van Den Abbeele, J.
Source: Self-asserted source
Jan Van Den Abbeele via Scopus - Elsevier

Trypanosoma brucei Parasites Occupy and Functionally Adapt to the Adipose Tissue in Mice

Cell Host and Microbe
2016 | Journal article
DOI: 10.1016/j.chom.2016.05.002
EID:

2-s2.0-84969909575
Contributors: Trindade, S.; Rijo-Ferreira, F.; Carvalho, T.; Pinto-Neves, D.; Guegan, F.; Aresta-Branco, F.; Bento, F.; Young, S.A.; Pinto, A.; Van Den Abbeele, J. et al.
Source: Self-asserted source
Jan Van Den Abbeele via Scopus - Elsevier

Tsetse fly tolerance to T. brucei infection: Transcriptome analysis of trypanosome-associated changes in the tsetse fly salivary gland

BMC Genomics
2016 | Journal article
DOI: 10.1186/s12864-016-3283-0
EID:

2-s2.0-84997191001
Contributors: Matetovici, I.; Caljon, G.; Van Den Abbeele, J.
Source: Self-asserted source
Jan Van Den Abbeele via Scopus - Elsevier

Description of a Nanobody-based Competitive Immunoassay to Detect Tsetse Fly Exposure

PLoS Neglected Tropical Diseases
2015 | Journal article
DOI: 10.1371/journal.pntd.0003456
EID:

2-s2.0-84924079000
Contributors: Caljon, G.; Hussain, S.; Vermeiren, L.; Van Den Abbeele, J.
Source: Self-asserted source
Jan Van Den Abbeele via Scopus - Elsevier

Paternal transmission of a secondary symbiont during mating in the viviparous tsetse fly

Molecular Biology and Evolution
2015 | Journal article
DOI: 10.1093/molbev/msv077
EID:

2-s2.0-84965182365
Contributors: De Vooght, L.; Caljon, G.; Van Hees, J.; Van Den Abbeele, J.
Source: Self-asserted source
Jan Van Den Abbeele via Scopus - Elsevier

PCR and microsatellite analysis of diminazene aceturate resistance of bovine trypanosomes correlated to knowledge, attitude and practice of livestock keepers in South-Western Ethiopia

Acta Tropica
2015 | Journal article
DOI: 10.1016/j.actatropica.2015.02.015
EID:

2-s2.0-84925115576
Contributors: Moti, Y.; De Deken, R.; Thys, E.; Van Den Abbeele, J.; Duchateau, L.; Delespaux, V.
Source: Self-asserted source
Jan Van Den Abbeele via Scopus - Elsevier

Peptidomics of Neuropeptidergic Tissues of the Tsetse Fly Glossina morsitans morsitans

Journal of the American Society for Mass Spectrometry
2015 | Journal article
DOI: 10.1007/s13361-015-1248-1
EID:

2-s2.0-84947557043
Contributors: Caers, J.; Boonen, K.; Van Den Abbeele, J.; Van Rompay, L.; Schoofs, L.; Van Hiel, M.B.
Source: Self-asserted source
Jan Van Den Abbeele via Scopus - Elsevier

African trypanosome control in the insect vector and mammalian host

Trends in Parasitology
2014 | Journal article
DOI: 10.1016/j.pt.2014.08.006
EID:

2-s2.0-84908214264
Contributors: Beschin, A.; Van Den Abbeele, J.; De Baetselier, P.; Pays, E.
Source: Self-asserted source
Jan Van Den Abbeele via Scopus - Elsevier

Delivery of a functional anti-trypanosome nanobody in different tsetse fly tissues via a bacterial symbiont, sodalis glossinidius

Microbial Cell Factories
2014 | Journal article
DOI: 10.1186/s12934-014-0156-6
EID:

2-s2.0-84964316070
Contributors: De Vooght, L.; Caljon, G.; De Ridder, K.; Van Den Abbeele, J.
Source: Self-asserted source
Jan Van Den Abbeele via Scopus - Elsevier

Detection of african animal trypanosomes: The haematocrit centrifugation technique compared to PCR with samples stored on filter paper or in DNA protecting buffer

Veterinary Parasitology
2014 | Journal article
DOI: 10.1016/j.vetpar.2014.04.014
EID:

2-s2.0-84901608749
Contributors: Moti, Y.; Fikru, R.; Büscher, P.; Van Den Abbeele, J.; Duchateau, L.; Delespaux, V.
Source: Self-asserted source
Jan Van Den Abbeele via Scopus - Elsevier

Genome sequence of the tsetse fly (Glossina morsitans ): Vector of African trypanosomiasis

Science
2014 | Journal article
DOI: 10.1126/science.1249656
EID:

2-s2.0-84899560044
Contributors: Watanabe, J.; Hattori, M.; Berriman, M.; Lehane, M.J.; Hall, N.; Solano, P.; Aksoy, S.; Hide, W.; Touré, Y.; Attardo, G.M. et al.
Source: Self-asserted source
Jan Van Den Abbeele via Scopus - Elsevier

Hematopoietic stem/progenitor cell sources to generate reticulocytes for Plasmodium vivax culture

PLoS ONE
2014 | Journal article
DOI: 10.1371/journal.pone.0112496
EID:

2-s2.0-84911905912
Contributors: Noulin, F.; Manesia, J.K.; Rosanas-Urgell, A.; Erhart, A.; Borlon, C.; Van Den Abbeele, J.; D'Alessandro, U.; Verfaillie, C.M.
Source: Self-asserted source
Jan Van Den Abbeele via Scopus - Elsevier

MIF Contributes to Trypanosoma brucei Associated Immunopathogenicity Development

PLoS Pathogens
2014 | Journal article
DOI: 10.1371/journal.ppat.1004414
EID:

2-s2.0-84907584412
Contributors: Stijlemans, B.; Leng, L.; Brys, L.; Sparkes, A.; Vansintjan, L.; Caljon, G.; Raes, G.; Van Den Abbeele, J.; Van Ginderachter, J.A.; Beschin, A. et al.
Source: Self-asserted source
Jan Van Den Abbeele via Scopus - Elsevier
Items per page:
Page 1 of 3

Peer review (5 reviews for 4 publications/grants)

Review activity for Nature communications (1)
Review activity for Parasites & vectors. (1)
Review activity for PLoS neglected tropical diseases (2)
Review activity for Tropical animal health and production. (1)
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