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Employment (2)

University of Helsinki: Helsinki, FI

Employment
Source: check_circle
University of Helsinki

Wellcome Trust Sanger Institute: Cambridge, Cambridgeshire, GB

2008-04-14 to 2012-07-10
Employment
Source: Self-asserted source
Kimmo Palin

Education and qualifications (3)

University of Helsinki: Helsinki, FI

2003-02-22 to 2007-12-20 | PhD. (Department of Computer Science)
Education
Source: Self-asserted source
Kimmo Palin

University of Helsinki: Helsinki, FI

2002-02-23 to 2003-02-21 | MSc. (Department of Computer Science)
Education
Source: Self-asserted source
Kimmo Palin

University of Helsinki: Helsinki, FI

1998-09-01 to 2002-02-22 (Department of Computer Science)
Education
Source: Self-asserted source
Kimmo Palin

Works (46)

Transposable elements as tissue-specific enhancers in cancers of endodermal lineage

Nature Communications
2023-09-01 | Journal article
DOI: 10.1038/s41467-023-41081-4
Contributors: Konsta Karttunen; Divyesh Patel; Jihan Xia; Liangru Fei; Kimmo Palin; Lauri Aaltonen; Biswajyoti Sahu
Source: check_circle
Crossref

Transposable elements as tissue-specific enhancers in cancers of endodermal lineage

2022-12-16 | Preprint
DOI: 10.1101/2022.12.16.520732
Contributors: Konsta Karttunen; Divyesh Patel; Jihan Xia; Liangru Fei; Kimmo Palin; Lauri Aaltonen; Biswajyoti Sahu
Source: check_circle
Crossref

Parity associates with chromosomal damage in uterine leiomyomas

Nature Communications
2021-09-14 | Journal article
DOI: 10.1038/s41467-021-25806-x
Contributors: Heli Kuisma; Simona Bramante; Kristiina Rajamäki; Lauri J. Sipilä; Eevi Kaasinen; Jaana Kaukomaa; Kimmo Palin; Netta Mäkinen; Jari Sjöberg; Nanna Sarvilinna et al.
Source: check_circle
Crossref

Human cell transformation by combined lineage conversion and oncogene expression

Oncogene
2021-09-09 | Journal article
DOI: 10.1038/s41388-021-01940-0
Part of ISSN: 0950-9232
Part of ISSN: 1476-5594
Source: Self-asserted source
Kimmo Palin
grade
Preferred source (of 2)‎

Deficient H2A.Z deposition is associated with genesis of uterine leiomyoma.

Nature
2021-08-04 | Journal article
DOI: 10.1038/s41586-021-03747-1
PMID: 34349258
Source: Self-asserted source
Kimmo Palin

Genetic and Epigenetic Characteristics of Inflammatory Bowel Disease-Associated Colorectal Cancer.

Gastroenterology
2021-04-27 | Journal article
DOI: 10.1053/j.gastro.2021.04.042
PMID: 33930428
Source: Self-asserted source
Kimmo Palin

No evidence of EMAST in whole genome sequencing data from 248 colorectal cancers.

Genes, chromosomes & cancer
2021-02-19 | Journal article
DOI: 10.1002/gcc.22941
PMID: 33527622
Source: Self-asserted source
Kimmo Palin

Lack of an association between gallstone disease and bilirubin levels with risk of colorectal cancer: a Mendelian randomisation analysis.

British journal of cancer
2021-01-07 | Journal article
DOI: 10.1038/s41416-020-01211-x
PMID: 33414539
PMC: PMC7961009
Source: Self-asserted source
Kimmo Palin

Defining eligible patients for allele-selective chemotherapies targeting NAT2 in colorectal cancer

Scientific reports
2020 | Journal article
DOI: 10.1186/1472-6750-13-66
Part of ISSN: 2045-2322
Source: Self-asserted source
Kimmo Palin

Association analyses identify 31 new risk loci for colorectal cancer susceptibility

Nature communications
2019 | Journal article
DOI: 10.1038/s41467-019-09775-w
Part of ISSN: 2041-1723
Source: Self-asserted source
Kimmo Palin

Exome and immune cell score analyses reveal great variation within synchronous primary colorectal cancers

British journal of cancer
2019 | Journal article
DOI: 10.1038/s41416-019-0427-4
Part of ISSN: 0007-0920
Source: Self-asserted source
Kimmo Palin

Retrotransposon insertions can initiate colorectal cancer and are associated with poor survival

Nature communications
2019 | Journal article
DOI: 10.1101/443580
DOI: 10.1038/s41467-019-11770-0
Part of ISSN: 2041-1723
Source: Self-asserted source
Kimmo Palin
grade
Preferred source (of 2)‎

Modifiable pathways for colorectal cancer: a mendelian randomisation analysis.

The lancet. Gastroenterology & hepatology
2019-10-24 | Journal article
DOI: 10.1016/s2468-1253(19)30294-8
PMID: 31668584
PMC: PMC7026696
Source: Self-asserted source
Kimmo Palin
grade
Preferred source (of 2)‎

Discovery of potential causative mutations in human coding and noncoding genome with the interactive software BasePlayer

Nature protocols
2018 | Journal article
DOI: 10.1038/s41596-018-0052-3
Part of ISSN: 1754-2189
Source: Self-asserted source
Kimmo Palin

Exome-wide somatic mutation characterization of small bowel adenocarcinoma

PLoS genetics
2018 | Journal article
DOI: 10.1371/journal.pgen.1007200
Part of ISSN: 1553-7390
Source: Self-asserted source
Kimmo Palin

Genetic predisposition to uterine leiomyoma is determined by loci for genitourinary development and genome stability

eLife
2018 | Journal article
DOI: 10.7554/elife.37110
Part of ISSN: 2050-084X
Source: Self-asserted source
Kimmo Palin

Genome-wide association study and meta-analysis in Northern European populations replicate multiple colorectal cancer risk loci

International journal of cancer
2018 | Journal article
DOI: 10.1002/ijc.31076
Part of ISSN: 0020-7136
Source: Self-asserted source
Kimmo Palin

Contribution of allelic imbalance to colorectal cancer

Nature Communications
2018-09-10 | Journal article
DOI: 10.1038/s41467-018-06132-1
Contributors: Kimmo Palin; Esa Pitkänen; Mikko Turunen; Biswajyoti Sahu; Päivi Pihlajamaa; Teemu Kivioja; Eevi Kaasinen; Niko Välimäki; Ulrika A. Hänninen; Tatiana Cajuso et al.
Source: check_circle
Crossref

Comprehensive evaluation of coding region point mutations in microsatellite-unstable colorectal cancer.

EMBO molecular medicine
2018-09-01 | Journal article
DOI: 10.15252/emmm.201708552
PMID: 30108113
PMC: PMC6402450
Source: Self-asserted source
Kimmo Palin

Detection of subclonal L1 transductions in colorectal cancer by long-distance inverse-PCR and Nanopore sequencing

Scientific Reports
2017-11-06 | Journal article
DOI: 10.1038/s41598-017-15076-3
Contributors: Barun Pradhan; Tatiana Cajuso; Riku Katainen; Päivi Sulo; Tomas Tanskanen; Outi Kilpivaara; Esa Pitkänen; Lauri A. Aaltonen; Liisa Kauppi; Kimmo Palin
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Pro-inflammatory fatty acid profile and colorectal cancer risk

European Journal of Cancer
2017-10 | Journal article | Author
DOI: 10.1016/j.ejca.2017.07.034
SOURCE-WORK-ID:

c6c03299-0254-49e7-9935-ac1bec75708f

WOSUID:

000411333300026

EID:

2-s2.0-85027680152
Contributors: Sebastian May-Wilson; Amit Sud; Philip J. Law; Kimmo Palin; Sari Tuupanen; Alexandra Gylfe; Ulrika A. Hänninen; Tatiana Cajuso; Tomas Tanskanen; Johanna Kondelin et al.
Source: check_circle
University of Helsinki

Comprehensive Evaluation of Protein Coding Mononucleotide Microsatellites in Microsatellite-Unstable Colorectal Cancer

Cancer Research
2017-08-01 | Journal article | Author
DOI: 10.1158/0008-5472.CAN-17-0682
SOURCE-WORK-ID:

9572c67f-8c8e-4d6f-85ed-98a1bf32130b

WOSUID:

000406677800010

EID:

2-s2.0-85026746479
Contributors: Johanna Kondelin; Alexandra E. Gylfe; Sofie Lundgren; Tomas Tanskanen; Jiri Hamberg; Mervi Aavikko; Kimmo Palin; Heikki Ristolainen; Riku Katainen; Eevi Kaasinen et al.
Source: check_circle
University of Helsinki

Mendelian randomisation implicates hyperlipidaemia as a risk factor for colorectal cancer

International Journal of Cancer
2017-06-15 | Journal article | Author
DOI: 10.1002/ijc.30709
SOURCE-WORK-ID:

881214e7-d10b-4e6b-acf0-21d4bf88f10e

WOSUID:

000400158800009

EID:

2-s2.0-85017448757
Contributors: Henry Rodriguez-Broadbent; Philip J. Law; Amit Sud; Kimmo Palin; Sari Tuupanen; Alexandra Gylfe; Ulrika A. Hanninen; Tatiana Cajuso; Tomas Tanskanen; Johanna Kondelin et al.
Source: check_circle
University of Helsinki

Multiple clinical characteristics separate MED12-mutation-positive and -negative uterine leiomyomas

Scientific Reports
2017-04-21 | Journal article
DOI: 10.1038/s41598-017-01199-0
Contributors: Hanna-Riikka Heinonen; Annukka Pasanen; Oskari Heikinheimo; Tomas Tanskanen; Kimmo Palin; Jaana Tolvanen; Pia Vahteristo; Jari Sjöberg; Esa Pitkänen; Ralf Bützow et al.
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Fast motif matching revisited: high-order PWMs, SNPs and indels.

2016-12 | Journal article
DOI: 10.1093/bioinformatics/btw683
PMID: 28011774
Contributors: Korhonen JH; Palin K; Taipale J; Ukkonen E
Source: Self-asserted source
Kimmo Palin via Europe PubMed Central
grade
Preferred source (of 2)‎

Mendelian randomisation analysis strongly implicates adiposity with risk of developing colorectal cancer.

2016-06 | Journal article
DOI: 10.1038/bjc.2016.188
PMID: 27336604
Contributors: Jarvis D; Mitchell JS; Law PJ; Palin K; Tuupanen S; Gylfe A; Hänninen UA; Cajuso T; Tanskanen T; Kondelin J et al.
Source: Self-asserted source
Kimmo Palin via Europe PubMed Central
grade
Preferred source (of 2)‎

Variation at 2q35 (PNKD and TMBIM1) influences colorectal cancer risk and identifies a pleiotropic effect with inflammatory bowel disease

Human Molecular Genetics
2016-06-01 | Journal article
DOI: 10.1093/hmg/ddw087
SOURCE-WORK-ID:

68bbf3ad-f1fb-4533-b01f-96c6922e043d

WOSUID:

000388554700019

EID:

2-s2.0-84998636380

PMID: 27005424
Source: Self-asserted source
Kimmo Palin
grade
Preferred source (of 3)‎

Systematic search for rare variants in Finnish early-onset colorectal cancer patients.

2015 | Journal article
DOI:

10.1016/j.cancergen.2014.12.004

PMID:

25749350
Contributors: Tanskanen T; Gylfe AE; Katainen R; Taipale M; Renkonen-Sinisalo L; Järvinen H; Mecklin JP; Böhm J; Kilpivaara O; Pitkänen E et al.
Source: Self-asserted source
Kimmo Palin via Europe PubMed Central
grade
Preferred source (of 2)‎

CTCF/cohesin-binding sites are frequently mutated in cancer.

2015-07 | Journal article
DOI: 10.1038/ng.3335
PMID: 26053496
Contributors: Katainen R; Dave K; Pitkänen E; Palin K; Kivioja T; Välimäki N; Gylfe AE; Ristolainen H; Hänninen UA; Cajuso T et al.
Source: Self-asserted source
Kimmo Palin via Europe PubMed Central
grade
Preferred source (of 3)‎

Frequent L1 retrotranspositions originating from TTC28 in colorectal cancer

Oncotarget
2014 | Journal article
SOURCE-WORK-ID:

01ce8568-cbcd-4dba-a2c1-07b33fdd4464

WOSUID:

000332701300024

EID:

2-s2.0-84896893831

PMID: 24553397
Source: Self-asserted source
Kimmo Palin
grade
Preferred source (of 3)‎

Clinical characterization, genetic mapping and whole-genome sequence analysis of a novel autosomal recessive intellectual disability syndrome.

2014-10 | Journal article
DOI:

10.1016/j.ejmg.2014.07.002

PMID:

25078763
Contributors: Kaasinen E; Rahikkala E; Koivunen P; Miettinen S; Wamelink MM; Aavikko M; Palin K; Myllyharju J; Moilanen JS; Pajunen L et al.
Source: Self-asserted source
Kimmo Palin via Europe PubMed Central
grade
Preferred source (of 2)‎

Uterine leiomyoma-linked MED12 mutations disrupt mediator-associated CDK activity.

2014-05 | Journal article
DOI:

10.1016/j.celrep.2014.03.047

PMID:

24746821

PMC:

PMC4041330
Contributors: Turunen M; Spaeth JM; Keskitalo S; Park MJ; Kivioja T; Clark AD; Mäkinen N; Gao F; Palin K; Nurkkala H et al.
Source: Self-asserted source
Kimmo Palin via Europe PubMed Central
grade
Preferred source (of 2)‎

Identification of candidate oncogenes in human colorectal cancers with microsatellite instability.

2013-09 | Journal article
DOI:

10.1053/j.gastro.2013.05.015

PMID:

23684749
Contributors: Gylfe AE; Kondelin J; Turunen M; Ristolainen H; Katainen R; Pitkänen E; Kaasinen E; Rantanen V; Tanskanen T; Varjosalo M et al.
Source: Self-asserted source
Kimmo Palin via Europe PubMed Central
grade
Preferred source (of 2)‎

DNA-binding specificities of human transcription factors.

2013-01 | Journal article
DOI:

10.1016/j.cell.2012.12.009

PMID:

23332764
Contributors: Jolma A; Yan J; Whitington T; Toivonen J; Nitta KR; Rastas P; Morgunova E; Enge M; Taipale M; Wei G et al.
Source: Self-asserted source
Kimmo Palin via Europe PubMed Central
grade
Preferred source (of 2)‎

Bayesian refinement of association signals for 14 loci in 3 common diseases.

2012-12 | Journal article
DOI:

10.1038/ng.2435

PMID:

23104008

PMC:

PMC3791416
Contributors: Wellcome Trust Case Control Consortium; Maller JB; McVean G; Byrnes J; Vukcevic D; Palin K; Su Z; Howson JM; Auton A; Myers S et al.
Source: Self-asserted source
Kimmo Palin via Europe PubMed Central
grade
Preferred source (of 2)‎

Identity-by-descent-based phasing and imputation in founder populations using graphical models

Genetic Epidemiology
2011-12 | Journal article
DOI: 10.1002/gepi.20635
Part of ISSN: 0741-0395
Source: Self-asserted source
Kimmo Palin
grade
Preferred source (of 2)‎

Genome-wide analysis of ETS-family DNA-binding in vitro and in vivo

2010-07-07 | Journal article
DOI:

10.1038/emboj.2010.106
Source: Self-asserted source
Kimmo Palin

Multiplexed massively parallel SELEX for characterization of human transcription factor binding specificities.

2010-06 | Journal article
DOI:

10.1101/gr.100552.109

PMID:

20378718

PMC:

PMC2877582
Contributors: Jolma A; Kivioja T; Toivonen J; Cheng L; Wei G; Enge M; Taipale M; Vaquerizas JM; Yan J; Sillanpää MJ et al.
Source: Self-asserted source
Kimmo Palin via Europe PubMed Central

Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls

2010-04-01 | Journal article
DOI:

10.1038/nature08979
Source: Self-asserted source
Kimmo Palin

Integrating sequence, evolution and functional genomics in regulatory genomics

Genome Biology
2009 | Journal article
DOI: 10.1186/gb-2009-10-1-202
Part of ISSN: 1465-6906
Source: Self-asserted source
Kimmo Palin

The common colorectal cancer predisposition SNP rs6983267 at chromosome 8q24 confers potential to enhanced Wnt signaling

2009-08-28 | Journal article
DOI:

10.1038/ng.406
Source: Self-asserted source
Kimmo Palin

Computational methods for locating and analyzing conserved gene regulatory DNA elements

2007 | Dissertation or Thesis | Author
SOURCE-WORK-ID:

c76b7b7d-2af1-4e96-931f-7f649aea5576

ISBN: 978-952-10-4352-9
Contributors: Kimmo Palin
Source: check_circle
University of Helsinki

Genome-wide prediction of mammalian enhancers based on analysis of transcription-factor binding affinity

Cell
2006 | Journal article | Author
DOI: 10.1016/j.cell.2005.10.042
SOURCE-WORK-ID:

8978866a-fce7-49c0-8760-1c2944f553d2

WOSUID:

000234969600009

EID:

2-s2.0-30344439849
Contributors: Outi Hallikas; Kimmo Palin; Natalia Sinjushina; Reetta Rautiainen; Juha Matti Partanen; Esko Juhani Ukkonen; Jussi Taipale
Source: check_circle
University of Helsinki
grade
Preferred source (of 2)‎

Locating potential enhancer elements by comparative genomics using the EEL software

2006-06 | Journal article
DOI:

10.1038/nprot.2006.56
Source: Self-asserted source
Kimmo Palin

From gene networks to gene function.

2003-12 | Journal article
DOI:

10.1101/gr.1111403

PMID:

14656964

PMC:

PMC403798
Contributors: Schlitt T; Palin K; Rung J; Dietmann S; Lappe M; Ukkonen E; Brazma A
Source: Self-asserted source
Kimmo Palin via Europe PubMed Central

Correlating gene promoters and expression in gene disruption experiments.

2002 | Journal article
PMID:

12386000
Contributors: Palin K; Ukkonen E; Brazma A; Vilo J
Source: Self-asserted source
Kimmo Palin via Europe PubMed Central

Peer review (5 reviews for 4 publications/grants)

Review activity for BMC cancer (1)
Review activity for Heliyon. (1)
Review activity for Nature communications (2)
Review activity for npj genomic medicine. (1)
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