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Works (12)

The modern human aryl hydrocarbon receptor is more active when ancestralized by genome editing

Proceedings of the National Academy of Sciences
2024-05-28 | Journal article
DOI: 10.1073/pnas.2402159121
Contributors: Nelly Helmbrecht; Martin Lackner; Tomislav Maricic; Svante Pääbo
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Efficient high-precision homology-directed repair-dependent genome editing by HDRobust

Nature Methods
2023-09 | Journal article
DOI: 10.1038/s41592-023-01949-1
Contributors: Stephan Riesenberg; Philipp Kanis; Dominik Macak; Damian Wollny; Dorothee Düsterhöft; Johannes Kowalewski; Nelly Helmbrecht; Tomislav Maricic; Svante Pääbo
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Response to Comment on “Human TKTL1 implies greater neurogenesis in frontal neocortex of modern humans than Neanderthals”

Science
2023-03-10 | Journal article
DOI: 10.1126/science.adf2212
Contributors: Anneline Pinson; Tomislav Maricic; Hugo Zeberg; Svante Pääbo; Wieland B. Huttner
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The evolutionary history of human spindle genes includes back-and-forth gene flow with Neandertals

eLife
2022-07-11 | Journal article
DOI: 10.7554/eLife.75464
Contributors: Stéphane Peyrégne; Janet Kelso; Benjamin M Peter; Svante Pääbo
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Improved gRNA secondary structures allow editing of target sites resistant to CRISPR-Cas9 cleavage

Nature Communications
2022-01-25 | Journal article
DOI: 10.1038/s41467-022-28137-7
Contributors: Stephan Riesenberg; Nelly Helmbrecht; Philipp Kanis; Tomislav Maricic; Svante Pääbo
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A substitution in the glutathione reductase lowers electron leakage and inflammation in modern humans

Science Advances
2022-01-07 | Journal article
DOI: 10.1126/sciadv.abm1148
Contributors: Lucia Coppo; Pradeep Mishra; Nora Siefert; Arne Holmgren; Svante Pääbo; Hugo Zeberg
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The evolutionary history of human spindle genes includes back-and-forth gene flow with Neandertals

2021-11-30 | Preprint
DOI: 10.1101/2021.11.29.470407
Contributors: Stéphane Peyrégne; Janet Kelso; Benjamin M. Peter; Svante Pääbo
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The earliest Denisovans and their cultural adaptation

Nature Ecology & Evolution
2021-11-25 | Journal article
DOI: 10.1038/s41559-021-01581-2
Contributors: Samantha Brown; Diyendo Massilani; Maxim B. Kozlikin; Michael V. Shunkov; Anatoly P. Derevianko; Alexander Stoessel; Blair Jope-Street; Matthias Meyer; Janet Kelso; Svante Pääbo et al.
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Comment on “Reintroduction of the archaic variant of NOVA1 in cortical organoids alters neurodevelopment”

Science
2021-10-15 | Journal article
DOI: 10.1126/science.abi6060
Contributors: Tomislav Maricic; Nelly Helmbrecht; Stephan Riesenberg; Dominik Macak; Philipp Kanis; Martin Lackner; Agrafena Daria Pugach-Matveeva; Svante Pääbo
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Point-of-care bulk testing for SARS-CoV-2 by combining hybridization capture with improved colorimetric LAMP

Nature Communications
2021-03-05 | Journal article
DOI: 10.1038/s41467-021-21627-0
Contributors: Lukas Bokelmann; Olaf Nickel; Tomislav Maricic; Svante Pääbo; Matthias Meyer; Stephan Borte; Stephan Riesenberg
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A genomic region associated with protection against severe COVID-19 is inherited from Neandertals

Proceedings of the National Academy of Sciences
2021-03-02 | Journal article
DOI: 10.1073/pnas.2026309118
Contributors: Hugo Zeberg; Svante Pääbo
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The major genetic risk factor for severe COVID-19 is inherited from Neanderthals

Nature
2020-11-26 | Journal article
DOI: 10.1038/s41586-020-2818-3
Contributors: Hugo Zeberg; Svante Pääbo
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