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Works (28)

estiMAge: development of a DNA methylation clock to estimate the methylation age of single cells

Bioinformatics Advances
2024-12-26 | Journal article
DOI: 10.1093/bioadv/vbaf005
Contributors: Zoe Saßmannshausen; Lisa Blank; Llorenç Solé-Boldo; Frank Lyko; Günter Raddatz; Magnus Rattray
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Crossref

Refining the role of N6-methyladenosine in cancer

Current Opinion in Genetics & Development
2024-10 | Journal article
DOI: 10.1016/j.gde.2024.102242
Contributors: Jonas Koch; Frank Lyko
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Skin Rejuvenation by Modulation of DNA Methylation

Experimental Dermatology
2024-10 | Journal article
DOI: 10.1111/exd.70005
Contributors: Elke Grönniger; Heiner Max; Frank Lyko
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Time-resolved, integrated analysis of clonally evolving genomes

PLOS Genetics
2023-12-14 | Journal article
DOI: 10.1371/journal.pgen.1011085
Contributors: Carine Legrand; Ville Mustonen; Ranja Andriantsoa; Peter Lichter; Günter Raddatz; Frank Lyko
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Functionally distinct cancer-associated fibroblast subpopulations establish a tumor promoting environment in squamous cell carcinoma

Nature Communications
2023-09-05 | Journal article
DOI: 10.1038/s41467-023-41141-9
Contributors: Sabrina Schütz; Llorenç Solé-Boldo; Carlota Lucena-Porcel; Jochen Hoffmann; Alexander Brobeil; Anke S. Lonsdorf; Manuel Rodríguez-Paredes; Frank Lyko
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Distal memory in wound healing and cancer

Nature Cell Biology
2023-05 | Journal article
DOI: 10.1038/s41556-023-01132-w
Contributors: Frank Lyko
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Targeting epigenetic age to prevent cancer

Nature Reviews Bioengineering
2023-02-22 | Journal article
DOI: 10.1038/s44222-023-00046-4
Contributors: Marc Winnefeld; Frank Lyko
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Pathogen-Induced Epigenetic Modifications in Cancers: Implications for Prevention, Detection and Treatment of Cancers in Africa

Cancers
2021-12-01 | Journal article
DOI: 10.3390/cancers13236051
Contributors: Alexandra Lindsey Djomkam Zune; Charles Ochieng’ Olwal; Kesego Tapela; Oloche Owoicho; Nora Nghochuzie Nganyewo; Frank Lyko; Lily Paemka
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Phylogeographic reconstruction of the marbled crayfish origin

Communications Biology
2021-09-17 | Journal article
DOI: 10.1038/s42003-021-02609-w
Contributors: Julian Gutekunst; Olena Maiakovska; Katharina Hanna; Panagiotis Provataris; Hannes Horn; Stephan Wolf; Christopher E. Skelton; Nathan J. Dorn; Frank Lyko
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DAZAP2 acts as specifier of the p53 response to DNA damage

Nucleic Acids Research
2021-03-18 | Journal article
DOI: 10.1093/nar/gkab084
Contributors: Magdalena C Liebl; Jutta Moehlenbrink; Huong Becker; Günter Raddatz; Suhaib K Abdeen; Rami I Aqeilan; Frank Lyko; Thomas G Hofmann
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A chicken DNA methylation clock for the prediction of broiler health

Communications Biology
2021-01-18 | Journal article
DOI: 10.1038/s42003-020-01608-7
Contributors: Günter Raddatz; Ryan J. Arsenault; Bridget Aylward; Rose Whelan; Florian Böhl; Frank Lyko
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Rapid Epigenetic Adaptation in Animals and Its Role in Invasiveness

Integrative and Comparative Biology
2020-08-01 | Journal article
DOI: 10.1093/icb/icaa023
Contributors: Vitor Coutinho Carneiro; Frank Lyko
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Perceived socio-economic impacts of the marbled crayfish invasion in Madagascar

PLOS ONE
2020-04-15 | Journal article
DOI: 10.1371/journal.pone.0231773
Contributors: Ranja Andriantsoa; Francisco X Aguilar; Julia P. G. Jones; Vlad Achimescu; Heriniaina Randrianarison; Miary Raselimanana; Manjary Andriatsitohaina; Jeanne Rasamy; Frank Lyko
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Physiological properties and tailored feeds to support aquaculture of marbled crayfish in closed systems

2020-02-26 | Preprint
DOI: 10.1101/2020.02.25.964114
Contributors: Sina Tönges; Karthik Masagounder; Julian Gutekunst; Jasmin Lohbeck; Aubry K. Miller; Florian Böhl; Frank Lyko
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Ecological plasticity and commercial impact of invasive marbled crayfish populations in Madagascar

BMC Ecology
2019-12 | Journal article
DOI: 10.1186/s12898-019-0224-1
Contributors: Ranja Andriantsoa; Sina Tönges; Jörn Panteleit; Kathrin Theissinger; Vitor Coutinho Carneiro; Jeanne Rasamy; Frank Lyko
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Limited antibody specificity compromises epitranscriptomic analyses

Nature Communications
2019-12-11 | Journal article
DOI: 10.1038/s41467-019-13684-3
Contributors: Mark Helm; Frank Lyko; Yuri Motorin
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The importance of non-histone protein methylation in cancer therapy

Nature Reviews Molecular Cell Biology
2019-10-03 | Journal article
DOI: 10.1038/s41580-019-0147-x
Contributors: Manuel Rodríguez-Paredes; Frank Lyko
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DNA (de)methylation in embryonic stem cells controls CTCF-dependent chromatin boundaries

Genome Research
2019-05-04 | Journal article
DOI: 10.1101/gr.239707.118
Contributors: Laura Wiehle; Graeme J. Thorn; Günter Raddatz; Christopher T. Clarkson; Karsten Rippe; Frank Lyko; Achim Breiling; Vladimir B. Teif
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Crossref

BisAMP: A web-based pipeline for targeted RNA cytosine-5 methylation analysis

Methods
2019-03 | Journal article
DOI: 10.1016/j.ymeth.2018.10.013
Contributors: Felix Bormann; Francesca Tuorto; Cansu Cirzi; Frank Lyko; Carine Legrand
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The methylome of the marbled crayfish links gene body methylation to stable expression of poorly accessible genes

Epigenetics & Chromatin
2018-12 | Journal article
DOI: 10.1186/s13072-018-0229-6
Contributors: Fanny Gatzmann; Cassandra Falckenhayn; Julian Gutekunst; Katharina Hanna; Günter Raddatz; Vitor Coutinho Carneiro; Frank Lyko
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Dnmt1 has an essential function despite the absence of CpG DNA methylation in the red flour beetle Tribolium castaneum

Scientific Reports
2018-11-07 | Journal article
DOI: 10.1038/s41598-018-34701-3
Contributors: Nora K. E. Schulz; C. Isabel Wagner; Julia Ebeling; Günter Raddatz; Maike F. Diddens-de Buhr; Frank Lyko; Joachim Kurtz
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Dnmt1 has an essential function despite the absence of CpG DNA methylation in the red flour beetle Tribolium castaneum

2018-09-27 | Other
DOI: 10.1101/426890
Contributors: Nora KE Schulz; C Isabel Wagner; Julia Ebeling; Günter Raddatz; Maike F Diddens-de Buhr; Frank Lyko; Joachim Kurtz
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Queuosine‐modified tRNAs confer nutritional control of protein translation

The EMBO Journal
2018-09-14 | Journal article
DOI: 10.15252/embj.201899777
Contributors: Francesca Tuorto; Carine Legrand; Cansu Cirzi; Giuseppina Federico; Reinhard Liebers; Martin Müller; Ann E Ehrenhofer‐Murray; Gunnar Dittmar; Hermann‐Josef Gröne; Frank Lyko
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Clonal genome evolution and rapid invasive spread of the marbled crayfish

Nature Ecology & Evolution
2018-02-05 | Journal article
DOI: 10.1038/s41559-018-0467-9
Contributors: Julian Gutekunst; Ranja Andriantsoa; Cassandra Falckenhayn; Katharina Hanna; Wolfgang Stein; Jeanne Rasamy; Frank Lyko
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E-MTAB-5255 - Methylation profiling by array of a solitary Peutz-Jeghers colon polyp in a healthy individual

2017 | Dataset
OTHER-ID:

E-MTAB-5255
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EMBL-EBI

Statistically robust methylation calling for whole-transcriptome bisulfite sequencing reveals distinct methylation patterns for mouse RNAs

Genome Research
2017-09-06 | Journal article
DOI: 10.1101/gr.210666.116
Contributors: Carine Legrand; Francesca Tuorto; Mark Hartmann; Reinhard Liebers; Dominik Jacob; Mark Helm; Frank Lyko
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Genome recoding by tRNA modifications

Open Biology
2016-12 | Journal article
DOI: 10.1098/rsob.160287
Contributors: Francesca Tuorto; Frank Lyko
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De Novo assembly and annotation of the freshwater crayfish Astacus astacus transcriptome

Marine Genomics
2016-08 | Journal article
DOI: 10.1016/j.margen.2016.02.006
Contributors: Kathrin Theissinger; Cassandra Falckenhayn; Daniel Blande; Anna Toljamo; Julian Gutekunst; Jenny Makkonen; Japo Jussila; Frank Lyko; Anne Schrimpf; Ralf Schulz et al.
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Peer review (1 review for 1 publication/grant)

Review activity for Nature (1)
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