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Works (23)

A blood- and brain-based EWAS of smoking

2024-05-21 | Preprint
DOI: 10.1101/2024.05.21.24307663
Contributors: Aleksandra D. Chybowska; Elena Bernabeu; Paul Yousefi; Matthew Suderman; Robert F. Hillary; Richard Clark; Louise MacGillivray; Lee Murphy; Sarah E. Harris; Janie Corley et al.
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Crossref

Discovery of shared epigenetic pathways across human phenotypes

2024-04-16 | Preprint
DOI: 10.1101/2024.04.15.589547
Contributors: Ilse Krätschmer; Hannah M. Smith; Daniel L. McCartney; Elena Bernabeu; Mahdi Mahmoudi; Archie Campbell; Janie Corley; Sarah E Harris; Simon R. Cox; Riccardo E. Marioni et al.
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Crossref

General and specific patterns of cortical gene expression as spatial correlates of complex cognitive functioning

Human Brain Mapping
2024-03 | Journal article
DOI: 10.1002/hbm.26641
Contributors: Joanna E. Moodie; Sarah E. Harris; Mathew A. Harris; Colin R. Buchanan; Gail Davies; Adele Taylor; Paul Redmond; David C. M. Liewald; Maria del C. Valdés Hernández; Susan Shenkin et al.
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Crossref

Genetic control of DNA methylation is largely shared across European and East Asian populations

Nature Communications
2024-03-28 | Journal article
DOI: 10.1038/s41467-024-47005-0
Contributors: Alesha A. Hatton; Fei-Fei Cheng; Tian Lin; Ren-Juan Shen; Jie Chen; Zhili Zheng; Jia Qu; Fan Lyu; Sarah E. Harris; Simon R. Cox et al.
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Crossref

Predictors of longitudinal cognitive ageing from age 70 to 82 including APOE e4 status, early-life and lifestyle factors: the Lothian Birth Cohort 1936

Molecular Psychiatry
2023-03 | Journal article
DOI: 10.1038/s41380-022-01900-4
Contributors: Janie Corley; Federica Conte; Sarah E. Harris; Adele M. Taylor; Paul Redmond; Tom C. Russ; Ian J. Deary; Simon R. Cox
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Crossref

General and specific patterns of cortical gene expression as spatial correlates of complex cognitive functioning

2023-03-17 | Preprint
DOI: 10.1101/2023.03.16.532915
Contributors: Joanna E. Moodie; Sarah E. Harris; Mathew A. Harris; Colin R. Buchanan; Gail Davies; Adele Taylor; Paul Redmond; David Liewald; Maria del C Valdés Hernández; Susan Shenkin et al.
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Crossref

Refining epigenetic prediction of chronological and biological age

2022-09-12 | Preprint
DOI: 10.1101/2022.09.08.507115
Contributors: Elena Bernabeu; Daniel L McCartney; Danni A Gadd; Robert F Hillary; Ake T Lu; Lee Murphy; Nicola Wrobel; Archie Campbell; Sarah E Harris; David Liewald et al.
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Crossref

Circulating Metabolome and White Matter Hyperintensities in Women and Men

Circulation
2022-04-05 | Journal article
DOI: 10.1161/CIRCULATIONAHA.121.056892
Contributors: Eeva Sliz; Jean Shin; Shahzad Ahmad; Dylan M. Williams; Stefan Frenzel; Friederike Gauß; Sarah E. Harris; Ann-Kristin Henning; Maria Valdes Hernandez; Yi-Han Hu et al.
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Crossref

Meta-GWAS Reveals Novel Genetic Variants Associated with Urinary Excretion of Uromodulin

Journal of the American Society of Nephrology
2022-03 | Journal article
DOI: 10.1681/ASN.2021040491
Contributors: Christina B. Joseph; Marta Mariniello; Ayumi Yoshifuji; Guglielmo Schiano; Jennifer Lake; Jonathan Marten; Anne Richmond; Jennifer E. Huffman; Archie Campbell; Sarah E. Harris et al.
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The genetic and epigenetic profile of serum S100β in the Lothian Birth Cohort 1936 and its relationship to Alzheimer’s disease

Wellcome Open Research
2022-01-27 | Journal article
DOI: 10.12688/wellcomeopenres.17322.2
Contributors: Danni A Gadd; Robert I McGeachan; Robert F Hillary; Daniel L McCartney; Sarah E Harris; Roy A Sherwood; N Joan Abbott; Simon R Cox; Riccardo E Marioni
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Crossref

DNA Methylation and Protein Markers of Chronic Inflammation and Their Associations With Brain and Cognitive Aging

Neurology
2021-12-07 | Journal article
DOI: 10.1212/WNL.0000000000012997
Contributors: Eleanor L.S. Conole; Anna J. Stevenson; Susana Muñoz Maniega; Sarah E. Harris; Claire Green; Maria del C. Valdés Hernández; Mathew A. Harris; Mark E. Bastin; Joanna M. Wardlaw; Ian J. Deary et al.
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Crossref

Association between plasma phospho-tau181 and cognitive change from age 73 to 82: Lothian Birth Cohort 1936

2021-11-25 | Other
DOI: 10.1101/2021.11.24.469836
Contributors: Tyler S. Saunders; Amanda Heslegrave; Declan King; Sarah Harris; Craig Ritchie; Graciela Muniz-Terrera; Ian J. Deary; Simon R. Cox; Henrik Zetterberg; Tara Spires-Jones
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Crossref

The genetic and epigenetic profile of serum S100β in the Lothian Birth Cohort 1936 and its relationship to Alzheimer’s disease [version 1; peer review: 2 approved]

2021-11-10 | Journal article
DOI: 10.12688/wellcomeopenres.17322.1
Part of ISSN: 2398-502X
Funded by GRANT_NUMBER:

(Pilot Fund award)

Funded by GRANT_NUMBER:

108890/Z/15/Z

Funded by GRANT_NUMBER:

221890/Z/20/Z

Funded by GRANT_NUMBER:

ARUK-PG2017B−10

Funded by GRANT_NUMBER:

AS-PG-19b-010

Funded by GRANT_NUMBER:

BB/F019394/1

Funded by GRANT_NUMBER:

G0701120, G1001245, MR/M013111/1, MR/R024065/1

Funded by GRANT_NUMBER:

MR/K026992/1

Funded by GRANT_NUMBER:

R01AG054628 and R01AG05462802S1

Funded by GRANT_NUMBER:

[Grant code unknown]
Contributors: Danni A Gadd; Robert I McGeachan; Robert F Hillary; Daniel L McCartney; Sarah E Harris; Roy A Sherwood; N Joan Abbott; Simon R Cox; Riccardo E Marioni; A Gadd Danni et al.
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Wellcome Open Research
grade
Preferred source (of 2)‎

An epigenetic predictor of death captures multi-modal measures of brain health

Molecular Psychiatry
2021-08-03 | Journal article
DOI: 10.1038/s41380-019-0616-9
Contributors: Robert F. Hillary; Anna J. Stevenson; Simon R. Cox; Daniel L. McCartney; Sarah E. Harris; Anne Seeboth; Jon Higham; Duncan Sproul; Adele M. Taylor; Paul Redmond et al.
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Crossref

Plasma lipid and liporotein biomarkers in LBC1936: Do they predict general cognitive ability and brain structure?

2020-07-10 | Preprint
DOI: 10.1101/2020.07.09.194688
Contributors: Sarah E. Harris; Stuart J Ritchie; Gonçalo D S Correia; Beatriz Jiménez; Chloe Fawns-Ritchie; Alison Pattie; Janie Corley; Susana Muñoz Maniega; Maria Valdés Hernández; John M. Starr et al.
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Crossref

Variants associated with HHIP expression have sex-differential effects on lung function [version 1; peer review: 2 approved]

2020-06-01 | Journal article
DOI: 10.12688/wellcomeopenres.15846.1
Part of ISSN: 2398-502X
Contributors: Katherine A. Fawcett; Ma'en Obeidat; Carl Melbourne; Nick Shrine; Anna L. Guyatt; Catherine John; Jian'an Luan; Anne Richmond; Marta R. Moksnes; Raquel Granell et al.
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Wellcome Open Research

Neurology-related protein biomarkers are associated with cognitive ability and brain volume in older age

Nature Communications
2020-02-10 | Journal article
DOI: 10.1038/s41467-019-14161-7
Contributors: Sarah E. Harris; Simon R. Cox; Steven Bell; Riccardo E. Marioni; Bram P. Prins; Alison Pattie; Janie Corley; Susana Muñoz Maniega; Maria Valdés Hernández; Zoe Morris et al.
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Crossref

Using regulatory variants to detect gene–gene interactions identifies networks of genes linked to cell immortalisation

Nature Communications
2020-01-17 | Journal article
DOI: 10.1038/s41467-019-13762-6
Contributors: D. Wragg; Q. Liu; Z. Lin; V. Riggio; C. A. Pugh; A. J. Beveridge; H. Brown; D. A. Hume; S. E. Harris; I. J. Deary et al.
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Crossref

Epigenetic signatures of smoking associate with cognitive function, brain structure, and mental and physical health outcomes in the Lothian Birth Cohort 1936

Translational Psychiatry
2019-10-07 | Journal article
DOI: 10.1038/s41398-019-0576-5
Contributors: Janie Corley; Simon R. Cox; Sarah E. Harris; Maria Valdéz Hernandez; Susana Muñoz Maniega; Mark E. Bastin; Joanna M. Wardlaw; John M. Starr; Riccardo E. Marioni; Ian J. Deary
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Crossref

Meta-analysis of exome array data identifies six novel genetic loci for lung function [version 3; referees: 2 approved]

2018-08-07 | Journal article
DOI: 10.12688/wellcomeopenres.12583.3
Part of ISSN: 2398-502X
Contributors: Victoria E. Jackson; Jeanne C. Latourelle; Louise V. Wain; Albert V. Smith; Megan L. Grove; Traci M. Bartz; Ma'en Obeidat; Michael A. Province; Wei Gao; Beenish Qaiser et al.
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Wellcome Open Research

Reversal of endothelial dysfunction reduces white matter vulnerability in cerebral small vessel disease in rats

Science Translational Medicine
2018-07-04 | Journal article
DOI: 10.1126/scitranslmed.aam9507
Contributors: Rikesh M. Rajani; Sophie Quick; Silvie R. Ruigrok; Delyth Graham; Sarah E. Harris; Benjamin F. J. Verhaaren; Myriam Fornage; Sudha Seshadri; Santosh S. Atanur; Anna F. Dominiczak et al.
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Crossref

Meta-analysis of exome array data identifies six novel genetic loci for lung function [version 2; referees: 1 approved, 1 approved with reservations]

2018-06-21 | Journal article
DOI: 10.12688/wellcomeopenres.12583.2
Part of ISSN: 2398-502X
Contributors: Victoria E. Jackson; Jeanne C. Latourelle; Louise V. Wain; Albert V. Smith; Megan L. Grove; Traci M. Bartz; Ma'en Obeidat; Michael A. Province; Wei Gao; Beenish Qaiser et al.
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Wellcome Open Research

Linked mutations at adjacent nucleotides have shaped human population differentiation and protein evolution

2018-05-23 | Other
DOI: 10.1101/329292
Contributors: James G. D. Prendergast; Carys Pugh; Sarah E. Harris; David A. Hume; Ian J. Deary; Allan Beveridge
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Crossref

Peer review (5 reviews for 4 publications/grants)

Review activity for Molecular brain (1)
Review activity for Nature communications (1)
Review activity for Neurobiology of aging. (2)
Review activity for Neuropsychopharmacology. (1)
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