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ResearcherID: G-9142-2018
ResearcherID: G-9142-2018

Keywords

retroviruses, flavivirises, capsid, assembly, RNA, interaction, coronavirus

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Czech Republic

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Employment (1)

Vysoká škola chemicko-technologická v Praze: Praha, Praha, CZ

Head of Molecular Biology lab (Biotechnology)
Employment
Source: Self-asserted source
Michaela Rumlova

Works (50 of 96)

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Developing Allosteric Inhibitors of SARS-CoV-2 RNA-Dependent RNA Polymerase

ChemMedChem
2024 | Journal article
DOI: 10.1002/CMDC.202400367
WOSUID: WOS:001328249800001
Contributors: Chayka, Artem; Danda, Matej; Dostalkova, Alzbeta; Spiwok, Vojtech; Klimesova, Anna; Kapisheva, Marina; Zgarbova, Michala; Weber, Jan; Ruml, Tomas; Rumlova, Michaela et al.
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PEGylated Molybdenum-Iodine Nanocluster as a Promising Radiodynamic Agent against Prostatic Adenocarcinoma

Inorganic Chemistry
2024 | Journal article
DOI: 10.1021/ACS.INORGCHEM.4C00084
WOSUID: WOS:001166802200001
Contributors: Pribyl, Tomas; Rumlova, Michaela; Mikyskova, Romana; Reinis, Milan; Kana, Antonin; Skoch, Karel; Zelenka, Jaroslav; Kirakci, Kaplan; Ruml, Tomas; Lang, Kamil
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Unveiling the DHX15-G-patch interplay in retroviral RNA packaging

Proceedings of the National Academy of Sciences
2024 | Journal article
DOI: 10.1073/PNAS.2407990121
WOSUID: WOS:001348579900005
Contributors: Dostalkova, Alzbeta; Krizova, Ivana; Junkova, Petra; Rackova, Jana; Kapisheva, Marina; Novotny, Radim; Danda, Matej; Zvonarova, Karolina; Sinkovec, Larisa; Vecerkova, Katerina et al.
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Biochemical characterization of naturally occurring mutations in SARS‐CoV‐2 RNA‐dependent RNA polymerase

Protein Science
2024-09 | Journal article
DOI: 10.1002/pro.5103
Contributors: Matěj Danda; Anna Klimešová; Klára Kušková; Alžběta Dostálková; Aneta Pagáčová; Jan Prchal; Marina Kapisheva; Tomáš Ruml; Michaela Rumlová
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Biochemical characterization of naturally occurring mutations in SARS-CoV-2 RNA-dependent RNA polymerase

2024-02-26 | Preprint
DOI: 10.1101/2024.02.24.581855
Contributors: Matěj Danda; Anna Klimešová; Klára Kušková; Alžběta Dostálková; Aneta Pagáčová; Jan Prchal; Marina Kapisheva; Tomáš Ruml; Michaela Rumlová
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Design, Synthesis, Biological Evaluation, and Crystallographic Study of Novel Purine Nucleoside Phosphorylase Inhibitors

Journal of Medicinal Chemistry
2023 | Journal article
DOI: 10.1021/ACS.JMEDCHEM.2C02097
WOSUID: WOS:000985510500001
Contributors: Skacel, Jan; Djukic, Stefan; Baszczynski, Ondrej; Kalcic, Filip; Bilek, Tadeas; Chalupsky, Karel; Kozak, Jaroslav; Dvorakova, Alexandra; Tloust'ova, Eva; Kral'ova, Zuzana et al.
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Monitoring of monkeypox viral DNA in Prague wastewater

Science of the Total Environment
2023 | Journal article
DOI: 10.1016/J.SCITOTENV.2023.166110
WOSUID: WOS:001057942100001
Contributors: Bartackova, Jana; Kouba, Vojtech; Dostalkova, Alzbeta; Cermakova, Eliska; Marin, Marco A. Lopez; Chmel, Martin; Milanova, Marcela; Demnerova, Katerina; Rumlova, Michaela; Sykora, Petr et al.
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National Institute of Virology and Bacteriology - a Reaction to Threats of Future Pandemics

Chemicke Listy
2023 | Journal article
DOI: 10.54779/CHL20230393
WOSUID: WOS:001034283700001
Contributors: Rumlova, Michaela; Ruml, Tomas
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A Cell Membrane Targeting Molybdenum-Iodine Nanocluster:Rational Ligand Design toward Enhanced Photodynamic Activity

Inorganic Chemistry
2022 | Journal article
DOI: 10.1021/ACS.INORGCHEM.2C00040
WOSUID: WOS:000779822100028
Contributors: Kirakci, Kaplan; Kubanova, Michaela; Pribyl, Tomas; Rumlova, Michaela; Zelenka, Jaroslav; Ruml, Tomas; Lang, Kamil
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Alteration in DNA-binding affinity of Wilms tumor 1 protein due to <i>WT1</i> genetic variants associated with steroid - resistant nephrotic syndrome in children

Scientific Reports
2022 | Journal article
DOI: 10.1038/S41598-022-12760-X
WOSUID: WOS:000799975800091
Contributors: Bezdicka, Martin; Kaufman, Filip; Krizova, Ivana; Dostalkova, Alzbeta; Rumlova, Michaela; Seeman, Tomas; Vondrak, Karel; Fencl, Filip; Zieg, Jakub; Soucek, Ondrej
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Avenue to X-ray-induced photodynamic therapy of prostatic carcinoma with octahedral molybdenum cluster nanoparticles

Journal of Materials Chemistry B
2022 | Journal article
DOI: 10.1039/D2TB00141A
WOSUID: WOS:000778336400001
Contributors: Koncosova, Martina; Rumlova, Michaela; Mikyskova, Romana; Reinis, Milan; Zelenka, Jaroslav; Ruml, Tomas; Kirakci, Kaplan; Lang, Kamil
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Fullerene Derivatives Prevent Packaging of Viral Genomic RNA into HIV-1 Particles by Binding Nucleocapsid Protein (vol 13, 2451, 2021)

Viruses
2022 | Journal article
DOI: 10.3390/V14061187
WOSUID: WOS:000817492600001
Contributors: Krizova, Ivana; Dostalkova, Alzbeta; Castro, Edison; Prchal, Jan; Hadravova, Romana; Kaufman, Filip; Hrabal, Richard; Ruml, Tomas; Llano, Manuel; Echegoyen, Luis et al.
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Integrative RNA profiling of TBEV-infected neurons and astrocytes reveals potential pathogenic effectors

Computational and Structural Biotechnology Journal
2022 | Journal article
DOI: 10.1016/J.CSBJ.2022.05.052
WOSUID: WOS:000814828600004
Contributors: Selinger, Martin; Vechtova, Pavlina; Tykalova, Hana; Oslejskova, Petra; Rumlova, Michaela; Sterba, Jan; Grubhoffer, Libor
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Monitoring COVID-19 spread in Prague local neighborhoods based on the presence of SARS-CoV-2 RNA in wastewater collected throughout the sewer network

Water Research
2022 | Journal article
DOI: 10.1016/J.WATRES.2022.118343
WOSUID: WOS:000795159400005
Contributors: Zdenkova, Kamila; Bartackova, Jana; Cermakova, Eliska; Demnerova, Katerina; Dostalkova, Alzbeta; Janda, Vaclav; Jarkovsky, Jiri; Marin, Marco Antonio Lopez; Novakova, Zuzana; Rumlova, Michaela et al.
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The analysis of differential expression and interactions of host and virus derived RNAs in human primary neural cells reveals candidate effectors of TBEV-induced neuropathogenesis

FEBS Open Bio
2022 | Journal article
WOSUID: WOS:000821444602003
Contributors: Selinger, M.; Vechtova, P.; Tykalova, H.; Oslejskova, P.; Rumlova, M.; Sterba, J.; Grubhoffer, L.
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Tick-borne encephalitis virus capsid protein induces translational shutoff as revealed by its structural-biological analysis

Journal of Biological Chemistry
2022 | Journal article
DOI: 10.1016/J.JBC.2022.102585
WOSUID: WOS:000917299600007
Contributors: Selinger, Martin; Novotny, Radim; Sys, Jakub; Roby, Justin A.; Tykalova, Hana; Ranjani, Ganji Sri; Vancova, Marie; Jaklova, Katerina; Kaufman, Filip; Bloom, Marshall E. et al.
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Betulinic Acid Decorated with Polar Groups and Blue Emitting BODIPY Dye: Synthesis, Cytotoxicity, Cell-Cycle Analysis and Anti-HIV Profiling

Biomedicines
2021 | Journal article
DOI: 10.3390/BIOMEDICINES9091104
WOSUID: WOS:000699283700001
Contributors: Kodr, David; Stankova, Jarmila; Rumlova, Michaela; Dzubak, Petr; Rehulka, Jiri; Zimmermann, Tomas; Krizova, Ivana; Gurska, Sona; Hajduch, Marian; Drasar, Pavel B. et al.
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Effect of Small Polyanions on In Vitro Assembly of Selected Members of Alpha-, Beta- and Gammaretroviruses

Viruses
2021 | Journal article
DOI: 10.3390/V13010129
WOSUID: WOS:000610811900001
Contributors: Dostalkova, Alzbeta; Vokata, Barbora; Kaufman, Filip; Ulbrich, Pavel; Ruml, Tomas; Rumlova, Michaela
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Fullerene Derivatives Prevent Packaging of Viral Genomic RNA into HIV-1 Particles by Binding Nucleocapsid Protein

Viruses
2021 | Journal article
DOI: 10.3390/V13122451
WOSUID: WOS:000737471500001
Contributors: Krizova, Ivana; Dostalkova, Alzbeta; Castro, Edison; Prchal, Jan; Hadravova, Romana; Kaufman, Filip; Hrabal, Richard; Ruml, Tomas; Llano, Manuel; Echegoyen, Luis et al.
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Heterocyclic Cathinones as Inhibitors of Kynurenine Aminotransferase II-Design, Synthesis, and Evaluation

Pharmaceuticals
2021 | Journal article
DOI: 10.3390/PH14121291
WOSUID: WOS:000736869700001
Contributors: Maryska, Michal; Svobodova, Lucie; Dehaen, Wim; Hrabinova, Martina; Rumlova, Michaela; Soukup, Ondrej; Kuchar, Martin
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Inhibition of Mitochondrial Metabolism Leads to Selective Eradication of Cells Adapted to Acidic Microenvironment

International Journal of Molecular Sciences
2021 | Journal article
DOI: 10.3390/IJMS221910790
WOSUID: WOS:000713203300001
Contributors: Koncosova, Martina; Vrzackova, Nikola; Krizova, Ivana; Tomasova, Petra; Rimpelova, Silvie; Dvorak, Ales; Vitek, Libor; Rumlova, Michaela; Ruml, Tomas; Zelenka, Jaroslav
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<i>In Vitro</i> Quantification of the Effects of IP6 and Other Small Polyanions on Immature HIV-1 Particle Assembly and Core Stability

Journal of Virology
2020 | Journal article
DOI: 10.1128/JVI.00991-20
WOSUID: WOS:000579827700010
Contributors: Dostalkova, Alzbeta; Kaufman, Filip; Krizova, Ivana; Vokata, Barbora; Ruml, Tomas; Rumlova, Michaela
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ANTITUMOR AND ANTI-HIV DERIVATIVES OF BETULINIC ACID

Chemicke Listy
2020 | Journal article
WOSUID: WOS:000580652400005
Contributors: Kodr, David; Rumlova, Michaela; Zimmermann, Tomas; Dzubak, Petr; Drasar, Pavel; Jurasek, Michal
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Characterization and <i>in vitro</i> assembly of tick-borne encephalitis virus C protein

FEBS Letters
2020 | Journal article
DOI: 10.1002/1873-3468.13857
WOSUID: WOS:000541746300013
Contributors: Kaufman, Filip; Dostalkova, Alzbeta; Pekarek, Lukas; Thanh, Tung Dinh; Kapisheva, Marina; Hadravova, Romana; Bednarova, Lucie; Novotny, Radim; Krizova, Ivana; Cerny, Jiri et al.
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Characterization of AMBN I and II Isoforms and Study of Their Ca2+-Binding Properties

International Journal of Molecular Sciences
2020 | Journal article
DOI: 10.3390/IJMS21239293
WOSUID: WOS:000597881700001
Contributors: Vetyskova, Veronika; Zouharova, Monika; Bednarova, Lucie; Vanek, Ondrej; Sazelova, Petra; Kasicka, Vaclav; Vymetal, Jiri; Srp, Jaroslav; Rumlova, Michaela; Charnavets, Tatsiana et al.
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PF74 and Its Novel Derivatives Stabilize Hexameric Lattice of HIV-1 Mature-Like Particles

Molecules
2020-04-20 | Journal article
DOI: 10.3390/molecules25081895
Contributors: Alžběta Dostálková; Kryštof Škach; Filip Kaufman; Ivana Křížová; Romana Hadravová; Martin Flegel; Tomáš Ruml; Richard Hrabal; Michaela Rumlová
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Cationic octahedral molybdenum cluster complexes functionalized with mitochondria-targeting ligands: photodynamic anticancer and antibacterial activities

Biomaterials Science
2019 | Journal article
DOI: 10.1039/C8BM01564C
WOSUID: WOS:000463746600011
Contributors: Kirakci, Kaplan; Zelenka, Jaroslav; Rumlova, Michaela; Cvacka, Josef; Ruml, Tomas; Lang, Kamil
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Phosphinate Apical Ligands: A Route to a Water-Stable Octahedral Molybdenum Cluster Complex

Inorganic Chemistry
2019 | Journal article
DOI: 10.1021/ACS.INORGCHEM.9B02569
WOSUID: WOS:000503330800025
Contributors: Kirakci, Kaplan; Demel, Jan; Hynek, Jan; Zelenka, Jaroslav; Rumlova, Michaela; Ruml, Tomas; Lang, Kamil
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Various AKIP1 Expression Levels Affect Its Subcellular Localization but Have no Effect on NF-κB Activation

Physiological Research
2019 | Journal article
DOI: 10.33549/PHYSIOLRES.933961
WOSUID: WOS:000476830200009
Contributors: Keprova, A.; Korinkova, L.; Krizova, I; Hadravova, R.; Kaufman, F.; Pichova, I; Ruml, T.; Rumlova, M.
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A simple, high-throughput stabilization assay to test HIV-1 uncoating inhibitors.

Scientific reports
2019-11-19 | Journal article
DOI: 10.1038/s41598-019-53483-w
PMID: 31745222
PMC: PMC6863892
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Michaela Rumlova
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Nuclear transport of nicotinamide phosphoribosyltransferase is cell cycle-dependent in mammalian cells, and its inhibition slows cell growth.

The Journal of biological chemistry
2019-04-11 | Journal article
DOI: 10.1074/jbc.ra118.003505
PMID: 30975903
PMC: PMC6552417
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Michaela Rumlova
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A Mason-Pfizer monkey virus Env-mCherry fusion vector allows visualization of viral precursors transport in cells using fluorescent microscopy

FEBS Open Bio
2018 | Journal article
WOSUID: WOS:000437674105042
Contributors: Grznarova, P.; Kolibova, S.; Lipov, J.; Hadravova, R.; Rumlova, M.; Hunter, E.; Ruml
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Conserved cysteines in Mason-Pfizer monkey virus capsid protein are essential for infectious mature particle formation

Virology
2018 | Journal article
DOI: 10.1016/J.VIROL.2018.06.001
WOSUID: WOS:000439956400012
Contributors: Pichalova, Ruzena; Fuzik, Tibor; Vokata, Barbora; Rumlova, Michaela; Llano, Manuel; Dostalkova, Alzbeta; Krizova, Ivana; Ruml, Tomas; Ulbrich, Pavel
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Heart Rate Variability During Long-Term Air Traffic Control in Cadets

International Conference on Telecommunications and Signal Processing (TSP)
2018 | Conference paper
DOI: 10.1109/TSP.2018.8441257
WOSUID: WOS:000454845100131
Contributors: Volf, Petr; Kutilek, Patrik; Hejda, Jan; Smrcka, Pavel; Krivanek, Vaclav; Doskocil, Radek; Farlik, Jan; Casar, Josef; Klikova, Michaela
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Mason-Pfizer Monkey Virus Envelope Glycoprotein Cycling and Its Vesicular Co-Transport with Immature Particles

Viruses
2018 | Journal article
DOI: 10.3390/V10100575
WOSUID: WOS:000448821200063
Contributors: Proksova, Petra Grznarova; Lipov, Jan; Zelenka, Jaroslav; Hunter, Eric; Langerova, Hana; Rumlova, Michaela; Ruml, Tomas
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Mutations of selected amino acids of Mason-Pfizer monkey virus capsid protein and their effects on its life cycle

FEBS Open Bio
2018 | Journal article
WOSUID: WOS:000437674102316
Contributors: Ctvrteckova, L.; Vokata, B.; Pichalova, R.; Todorovova, V.; Klimova, P.; Dostalkova, A.; Krizova, I.; Rumlova, M.; Ulbrich, P.; Ruml, T.
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New approach for testing inhibitors of HIV-1 uncoating

FEBS Open Bio
2018 | Journal article
WOSUID: WOS:000437674101001
Contributors: Dostalkova, A.; Hadravova, R.; Krizova, I.; Kaufman, F.; Ruml, T.; Rumlova, M.
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Octahedral molybdenum clusters as radiosensitizers for X-ray induced photodynamic therapy

Journal of Materials Chemistry B
2018 | Journal article
DOI: 10.1039/C8TB00893K
WOSUID: WOS:000437470100003
Contributors: Kirakci, Kaplan; Zelenka, Jaroslav; Rumlova, Michaela; Martincik, Jiri; Nikl, Martin; Ruml, Tomas; Lang, Kamil
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Proteomic analysis of host-cell proteins in Mason-Pfizer monkey virus

FEBS Open Bio
2018 | Journal article
WOSUID: WOS:000437674105181
Contributors: Blahova, T.; Junkova, P.; Moravcova, J.; Langerova, H.; Dostalkova, A.; Hynek, R.; Rumlova, M.
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Study of the role of cysteines present in Mason-Pfizer monkey virus capsid protein

FEBS Open Bio
2018 | Journal article
WOSUID: WOS:000437674102317
Contributors: Vokata, B.; Pichalova, R.; Fuzik, T.; Dostalkova, A.; Krizova, I.; Ulbrich, P.; Rumlova, M.; Ruml, T.
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Structure and architecture of immature and mature murine leukemia virus capsids.

Proceedings of the National Academy of Sciences of the United States of America
2018-11-26 | Journal article
DOI: 10.1073/pnas.1811580115
PMID: 30478053
PMC: PMC6294937
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Michaela Rumlova
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In vitro methods for testing antiviral drugs

Biotechnology Advances
2018-05 | Journal article
DOI: 10.1016/j.biotechadv.2017.12.016
Part of ISSN: 0734-9750
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Michaela Rumlova
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Mutations in the Basic Region of the Mason-Pfizer Monkey Virus Nucleocapsid Protein Affect Reverse Transcription, Genomic RNA Packaging, and the Virus Assembly Site.

Journal of virology
2018-04-27 | Journal article
DOI: 10.1128/jvi.00106-18
PMID: 29491167
PMC: PMC5923082
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Michaela Rumlova
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Does BCA3 Play a Role in the HIV-1 Replication Cycle?

Viruses
2018-04-20 | Journal article
DOI: 10.3390/v10040212
PMID: 29677171
PMC: PMC5923506
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Michaela Rumlova
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Conjugation of chlorins with spermine enhances phototoxicity to cancer cells in vitro

Journal of Photochemistry and Photobiology B: Biology
2017 | Journal article
DOI: 10.1016/J.JPHOTOBIOL.2017.02.012
WOSUID: WOS:000397689500022
Contributors: Darmostuk, Mariia; Jurasek, Michal; Lengyel, Kamila; Zelenka, Jaroslav; Rumlova, Michaela; Drasar, Pavel; Ruml, Tomas
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Methodology for screening of HIV inhibitors applicable for <i>in silico</i> designed molecules and empirical testing of traditional medicinal materials

Environmental Technology & Innovation
2017 | Journal article
WOSUID: WOS:000460265400005
Contributors: Rumlova, M.; Spiwok, V.; Ruml, T.; Hadravova, R.
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Optimized method for isolation of immature intracytoplasmic retroviral particles from mammalian cells

Journal of Virological Methods
2017 | Journal article
DOI: 10.1016/J.JVIROMET.2017.06.003
WOSUID: WOS:000412616900003
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Functional and Structural Characterization of Novel Type of Linker Connecting Capsid and Nucleocapsid Protein Domains in Murine Leukemia Virus

Journal of Biological Chemistry
2016 | Journal article
DOI: 10.1074/JBC.M116.746461
WOSUID: WOS:000384574800027
Contributors: Dolezal, Michal; Hadravova, Romana; Kozisek, Milan; Bednarova, Lucie; Langerova, Hana; Ruml, Tomas; Rumlova, Michaela
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Membrane Interactions of the Mason-Pfizer Monkey Virus Matrix Protein and Its Budding Deficient Mutants

Journal of Molecular Biology
2016 | Journal article
DOI: 10.1016/J.JMB.2016.10.010
WOSUID: WOS:000389110300009
Contributors: Kroupa, Tomas; Langerova, Hana; Dolezal, Michal; Prchal, Jan; Spiwok, Vojtech; Hunter, Eric; Rumlova, Michaela; Hrabal, Richard; Ruml, Tomas
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Nucleic Acid Binding by Mason-Pfizer Monkey Virus CA Promotes Virus Assembly and Genome Packaging

Journal of Virology
2016 | Journal article
DOI: 10.1128/JVI.03197-15
WOSUID: WOS:000375125400030
Contributors: Fuezik, Tibor; Pichalova, Ruzena; Schur, Florian K. M.; Strohalmova, Karolina; Krizova, Ivana; Hadravova, Romana; Rumlova, Michaela; Briggs, John A. G.; Ulbrich, Pavel; Ruml, Tomas
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Peer review (4 reviews for 3 publications/grants)

Review activity for International journal of molecular sciences. (1)
Review activity for PloS one. (1)
Review activity for Viruses. (2)
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