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Scopus Author ID: 7103373503
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Employment (9)

Bethanian Hospital for Psychiatry, Psychosomatics, and Psychotherapy : Greifswald, DE

2020-07-01 to present | Senior attending psychiatrist
Employment
Source: Self-asserted source
Wolfgang Sommer

Zentralinstitut für Seelische Gesundheit/Universität Heidelberg: Mannheim, Baden-Württemberg, DE

2008-09-01 to present | Deputy director/Group leader (Psychopharmacology)
Employment
Source: Self-asserted source
Wolfgang Sommer

National Institute on Alcohol Abuse and Alcoholism: Bethesda, MD, US

2004-11-01 to 2008-08-31 (Laboratory of Clinical and Translational Studies)
Employment
Source: Self-asserted source
Wolfgang Sommer

Karolinska Institutet-Huddinge Campus: Huddinge, Stockholm, SE

1998 to 2004 (Neurotec)
Employment
Source: Self-asserted source
Wolfgang Sommer

Karolinska Institutet: Stockholm, SE

1996 to 1998 (Clinical Neuroscience)
Employment
Source: Self-asserted source
Wolfgang Sommer

Karolinska Institutet: Stockholm, SE

1993 to 1996 (Neuroscience)
Employment
Source: Self-asserted source
Wolfgang Sommer

Max Delbrück Centrum für Molekulare Medizin Berlin Buch: Berlin-Buch, Berlin, DE

1991 to 1992 (Molekulare Virologie)
Employment
Source: Self-asserted source
Wolfgang Sommer

Max Delbrück Centrum für Molekulare Medizin Berlin Buch: Berlin-Buch, Berlin, DE

1991 to 1992 (Max-Planck-Arbeitsgruppe)
Employment
Source: Self-asserted source
Wolfgang Sommer

Zentralinstitut für Molekularbiologie: Berlin-Buch, DE

1987 to 1990 (Molekulare Virologie)
Employment
Source: Self-asserted source
Wolfgang Sommer

Education and qualifications (1)

Ernst-Moritz-Arndt Universität Greifswald: Greifswald, Mecklenburg-Vorpommern, DE

1981 to 1987
Education
Source: Self-asserted source
Wolfgang Sommer

Professional activities (1)

Faculty Opinions: London, GB

2010-06-07 to present | Associate Faculty Member
Invited position
Source: check_circle
Faculty Opinions

Works (50 of 151)

Items per page:
Page 1 of 4

Bad habits–good goals? Meta-analysis and translation of the habit construct to alcoholism

Translational Psychiatry
2024-07-19 | Journal article
DOI: 10.1038/s41398-024-02965-1
Contributors: F. Giannone; C. Ebrahimi; T. Endrass; A. C. Hansson; F. Schlagenhauf; W. H. Sommer
Source: check_circle
Crossref

Using naltrexone to validate a human laboratory test system to screen new medications for alcoholism (TESMA)- a randomized clinical trial

Translational Psychiatry
2023-04-05 | Journal article
DOI: 10.1038/s41398-023-02404-7
Contributors: Maik Spreer; Xina Grählert; Ina-Maria Klut; Feras Al Hamdan; Wolfgang H. Sommer; Martin H. Plawecki; Sean O’Connor; Michael Böttcher; Cathrin Sauer; Michael N. Smolka et al.
Source: check_circle
Crossref

Psychedelic Targeting of Metabotropic Glutamate Receptor 2 and Its Implications for the Treatment of Alcoholism

Cells
2023-03-22 | Journal article
DOI: 10.3390/cells12060963
Contributors: Kevin Domanegg; Wolfgang H. Sommer; Marcus W. Meinhardt
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Schrooms against booze: Potential of mycotherapy for the treatment of AUD

Neuropsychopharmacology
2023-01 | Journal article
DOI: 10.1038/s41386-022-01446-7
Contributors: Marcus W. Meinhardt; Wolfgang H. Sommer
Source: check_circle
Crossref

Generalized habitual tendencies in alcohol dependent rats

2022-10-10 | Preprint
DOI: 10.1101/2022.10.04.510642
Contributors: Francesco Giannone; Arian Hach; Magda Chrószcz; Marion M. Friske; Marcus Meinhardt; Rainer Spanagel; Wolfgang H. Sommer; Anita C. Hansson
Source: check_circle
Crossref

Repetitive Transcranial Magnetic Stimulation in Alcohol Dependence: A Randomized, Double-Blind, Sham-Controlled Proof-of-Concept Trial Targeting the Medial Prefrontal and Anterior Cingulate Cortices

Biological Psychiatry
2022-06 | Journal article
DOI: 10.1016/j.biopsych.2021.11.020
Contributors: Maayan Harel; Irene Perini; Robin Kämpe; Uri Alyagon; Hadar Shalev; Itay Besser; Wolfgang H. Sommer; Markus Heilig; Abraham Zangen
Source: check_circle
Crossref

From a systems view to spotting a hidden island: A narrative review implicating insula function in alcoholism

Neuropharmacology
2022-05 | Journal article
DOI: 10.1016/j.neuropharm.2022.108989
Contributors: Wolfgang H. Sommer; Santiago Canals; Angelo Bifone; Markus Heilig; Petri Hyytiä
Source: check_circle
Crossref

Brain Network Allostasis after Chronic Alcohol Drinking Is Characterized by Functional Dedifferentiation and Narrowing

The Journal of Neuroscience
2022-05-25 | Journal article
DOI: 10.1523/JNEUROSCI.0389-21.2022
Contributors: Úrsula Pérez-Ramírez; Víctor J. López-Madrona; Andrés Pérez-Segura; Vicente Pallarés; Andrea Moreno; Roberto Ciccocioppo; Petri Hyytiä; Wolfgang H. Sommer; David Moratal; Santiago Canals
Source: check_circle
Crossref

Disrupted circadian expression of β-arrestin 2 affects reward-related µ-opioid receptor function in alcohol dependence.

Journal of neurochemistry
2021-12-16 | Journal article
DOI: 10.1111/jnc.15559
PMID: 34919270
Source: Self-asserted source
Wolfgang Sommer

Psilocybin targets a common molecular mechanism for cognitive impairment and increased craving in alcoholism.

Science advances
2021-11-17 | Journal article
DOI: 10.1126/sciadv.abh2399
PMID: 34788104
PMC: PMC8598005
Source: Self-asserted source
Wolfgang Sommer

Increased network centrality of the anterior insula in early abstinence from alcohol.

Addiction biology
2021-08-31 | Journal article
DOI: 10.1111/adb.13096
PMID: 34467604
Source: Self-asserted source
Wolfgang Sommer

Baseline severity and the prediction of placebo response in clinical trials for alcohol dependence: A meta-regression analysis to develop an enrichment strategy.

Alcoholism, clinical and experimental research
2021-08-21 | Journal article
DOI: 10.1111/acer.14670
PMID: 34418121
Source: Self-asserted source
Wolfgang Sommer

Test-retest reliability of neural alcohol cue-reactivity: Is there light at the end of the magnetic resonance imaging tube?

Addiction biology
2021-06-15 | Journal article
DOI: 10.1111/adb.13069
PMID: 34132011
Source: Self-asserted source
Wolfgang Sommer

FMRI-based prediction of naltrexone response in alcohol use disorder: a replication study.

European archives of psychiatry and clinical neuroscience
2021-04-21 | Journal article
DOI: 10.1007/s00406-021-01259-7
PMID: 33884495
PMC: PMC8236024
Source: Self-asserted source
Wolfgang Sommer

Alcohol and sweet reward are encoded by distinct meta-ensembles.

Neuropharmacology
2021-02-11 | Journal article
DOI: 10.1016/j.neuropharm.2021.108496
PMID: 33582149
Source: Self-asserted source
Wolfgang Sommer
grade
Preferred source (of 2)‎

Calcium Carbonate Attenuates Withdrawal and Reduces Craving: A Randomized Controlled Trial in Alcohol-Dependent Patients.

European addiction research
2021-02-10 | Journal article
DOI: 10.1159/000512763
PMID: 33567423
Source: Self-asserted source
Wolfgang Sommer

Chronic alcohol consumption alters extracellular space geometry and transmitter diffusion in the brain.

Science advances
2020-06-24 | Journal article
DOI: 10.1126/sciadv.aba0154
PMID: 32637601
PMC: PMC7314532
Source: Self-asserted source
Wolfgang Sommer

Anterior insula stimulation suppresses appetitive behavior while inducing forebrain activation in alcohol-preferring rats

Translational Psychiatry
2020-05-18 | Journal article
DOI: 10.1038/s41398-020-0833-7
Contributors: Mia Haaranen; Giulia Scuppa; Stefano Tambalo; Vilja Järvi; Sine M. Bertozzi; Andrea Armirotti; Wolfgang H. Sommer; Angelo Bifone; Petri Hyytiä
Source: check_circle
Crossref

Impulsivity is a heritable trait in rodents and associated with a novel quantitative trait locus on chromosome 1.

Scientific reports
2020-04-21 | Journal article
DOI: 10.1038/s41598-020-63646-9
PMID: 32317713
PMC: PMC7174407
Source: Self-asserted source
Wolfgang Sommer

Interaction between behavioral inhibition and neural alcohol cue-reactivity in ADHD and alcohol use disorder.

Psychopharmacology
2020-04-13 | Journal article
DOI: 10.1007/s00213-020-05492-1
PMID: 32285159
PMC: PMC7239811
Source: Self-asserted source
Wolfgang Sommer

Addiction Research Consortium: Losing and regaining control over drug intake (ReCoDe)-From trajectories to mechanisms and interventions.

Addiction biology
2019-12-20 | Journal article
DOI: 10.1111/adb.12866
PMID: 31859437
Source: Self-asserted source
Wolfgang Sommer

Developing neuroscience-based treatments for alcohol addiction: A matter of choice?

Translational Psychiatry
2019-10-08 | Journal article
DOI: 10.1038/s41398-019-0591-6
Contributors: Markus Heilig; Eric Augier; Simone Pfarr; Wolfgang H. Sommer
Source: check_circle
Crossref

Detecting Alcohol-Induced Brain Damage Noninvasively Using Diffusion Tensor Imaging.

ACS chemical neuroscience
2019-09-12 | Journal article
DOI: 10.1021/acschemneuro.9b00481
PMID: 31513372
Source: Self-asserted source
Wolfgang Sommer

Dysregulation of the histone demethylase KDM6B in alcohol dependence is associated with epigenetic regulation of inflammatory signaling pathways.

Addiction biology
2019-08-01 | Journal article
DOI: 10.1111/adb.12816
PMID: 31373129
PMC: PMC7757263
Source: Self-asserted source
Wolfgang Sommer

Microstructural White Matter Alterations in Men With Alcohol Use Disorder and Rats With Excessive Alcohol Consumption During Early Abstinence.

JAMA psychiatry
2019-04-03 | Journal article
DOI: 10.1001/jamapsychiatry.2019.0318
PMID: 30942831
Source: Self-asserted source
Wolfgang Sommer

Aberrant insular cortex connectivity in abstinent alcohol-dependent rats is reversed by dopamine D3 receptor blockade.

Addiction biology
2019-03-24 | Journal article
DOI: 10.1111/adb.12744
PMID: 30907042
Source: Self-asserted source
Wolfgang Sommer

Incubation of neural alcohol cue reactivity after withdrawal and its blockade by naltrexone.

Addiction biology
2019-02-12 | Journal article
DOI: 10.1111/adb.12717
PMID: 30748046
Source: Self-asserted source
Wolfgang Sommer

Glutamate concentration in the anterior cingulate cortex in alcohol dependence: association with alcohol withdrawal and exploration of contribution from glutamatergic candidate genes.

Psychiatric genetics
2018-10-01 | Journal article
DOI: 10.1097/YPG.0000000000000202
PMID: 29985185
PMC: PMC6133199
Source: Self-asserted source
Wolfgang Sommer
grade
Preferred source (of 2)‎

Dopamine and opioid systems adaptation in alcoholism revisited: Convergent evidence from positron emission tomography and postmortem studies.

Neuroscience and biobehavioral reviews
2018-09-19 | Journal article
DOI: 10.1016/j.neubiorev.2018.09.010
PMID: 30243576
Source: Self-asserted source
Wolfgang Sommer

Efficacy and safety of sodium oxybate in alcohol-dependent patients with a very high drinking risk level.

Addiction biology
2018-07-01 | Journal article
DOI: 10.1111/adb.12645
PMID: 30043457
Source: Self-asserted source
Wolfgang Sommer

Targeted overexpression of CRH receptor subtype 1 in central amygdala neurons: effect on alcohol-seeking behavior.

Psychopharmacology
2018-04-26 | Journal article
DOI: 10.1007/s00213-018-4908-6
PMID: 29700576
Source: Self-asserted source
Wolfgang Sommer
grade
Preferred source (of 2)‎

Choice for Drug or Natural Reward Engages Largely Overlapping Neuronal Ensembles in the Infralimbic Prefrontal Cortex.

The Journal of neuroscience : the official journal of the Society for Neuroscience
2018-02-26 | Journal article
DOI: 10.1523/jneurosci.0026-18.2018
PMID: 29483279
Source: Self-asserted source
Wolfgang Sommer

Dynorphin and κ-Opioid Receptor Dysregulation in the Dopaminergic Reward System of Human Alcoholics.

Molecular neurobiology
2018-01-30 | Journal article
DOI: 10.1007/s12035-017-0844-4
PMID: 29383684
PMC: PMC6061161
Source: Self-asserted source
Wolfgang Sommer

The SyBil-AA real-time fMRI neurofeedback study: protocol of a single-blind randomized controlled trial in alcohol use disorder.

BMC psychiatry
2018-01-17 | Journal article
DOI: 10.1186/s12888-018-1604-3
PMID: 29343230
PMC: PMC5773029
Source: Self-asserted source
Wolfgang Sommer
grade
Preferred source (of 2)‎

Deep grey matter iron accumulation in alcohol use disorder

NeuroImage
2017 | Journal article
DOI: 10.1016/j.neuroimage.2017.01.007
EID:

2-s2.0-85009740982
Contributors: Juhás, M.; Sun, H.; Brown, M.R.G.; MacKay, M.B.; Mann, K.F.; Sommer, W.H.; Wilman, A.H.; Dursun, S.M.; Greenshaw, A.J.
Source: Self-asserted source
Wolfgang Sommer via Scopus - Elsevier

Differential Roles for L-Type Calcium Channel Subtypes in Alcohol Dependence

Neuropsychopharmacology
2017 | Journal article
DOI: 10.1038/npp.2016.266
EID:

2-s2.0-85008319010
Contributors: Uhrig, S.; Vandael, D.; Marcantoni, A.; Dedic, N.; Bilbao, A.; Vogt, M.A.; Hirth, N.; Broccoli, L.; Bernardi, R.E.; Schönig, K. et al.
Source: Self-asserted source
Wolfgang Sommer via Scopus - Elsevier

Early rearing history influences oxytocin receptor epigenetic regulation in rhesus macaques

Proceedings of the National Academy of Sciences of the United States of America
2017 | Journal article
DOI: 10.1073/pnas.1706206114
EID:

2-s2.0-85032733624
Contributors: Baker, M.; Lindell, S.G.; Driscoll, C.A.; Zhou, Z.; Yuan, Q.; Schwandt, M.L.; Miller-Crews, I.; Simpson, E.A.; Paukner, A.; Ferrari, P.F. et al.
Source: Self-asserted source
Wolfgang Sommer via Scopus - Elsevier

Evaluating network brain connectivity in alcohol postdependent state using Network-Based Statistic

Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
2017 | Conference paper
DOI: 10.1109/EMBC.2017.8036879
EID:

2-s2.0-85032205628
Contributors: Diaz-Parra, A.; Perez-Ramirez, U.; Pacheco-Torres, J.; Pfarr, S.; Sommer, W.H.; Moratal, D.; Canals, S.
Source: Self-asserted source
Wolfgang Sommer via Scopus - Elsevier

Genetic contribution to alcohol dependence: investigation of a heterogeneous German sample of individuals with alcohol dependence, chronic alcoholic pancreatitis, and alcohol-related cirrhosis

Genes
2017 | Journal article
DOI: 10.3390/genes8070183
EID:

2-s2.0-85025661673
Contributors: Treutlein, J.; Frank, J.; Streit, F.; Reinbold, C.S.; Juraeva, D.; Degenhardt, F.; Rietschel, L.; Witt, S.H.; Forstner, A.J.; Ridinger, M. et al.
Source: Self-asserted source
Wolfgang Sommer via Scopus - Elsevier

Multi-modal MRI classifiers identify excessive alcohol consumption and treatment effects in the brain

Addiction Biology
2017 | Journal article
DOI: 10.1111/adb.12418
EID:

2-s2.0-84973867004
Contributors: Cosa, A.; Moreno, A.; Pacheco-Torres, J.; Ciccocioppo, R.; Hyytiä, P.; Sommer, W.H.; Moratal, D.; Canals, S.
Source: Self-asserted source
Wolfgang Sommer via Scopus - Elsevier

Negative Association Between MR-Spectroscopic Glutamate Markers and Gray Matter Volume After Alcohol Withdrawal in the Hippocampus: A Translational Study in Humans and Rats

Alcoholism: Clinical and Experimental Research
2017 | Journal article
DOI: 10.1111/acer.13308
EID:

2-s2.0-85009758514
Contributors: Frischknecht, U.; Hermann, D.; Tunc-Skarka, N.; Wang, G.-Y.; Sack, M.; van Eijk, J.; Demirakca, T.; Falfan-Melgoza, C.; Krumm, B.; Dieter, S. et al.
Source: Self-asserted source
Wolfgang Sommer via Scopus - Elsevier

Reprogramming of mPFC transcriptome and function in alcohol dependence

Genes, Brain and Behavior
2017 | Journal article
DOI: 10.1111/gbb.12344
EID:

2-s2.0-85006088621
Contributors: Heilig, M.; Barbier, E.; Johnstone, A.L.; Tapocik, J.; Meinhardt, M.W.; Pfarr, S.; Wahlestedt, C.; Sommer, W.H.
Source: Self-asserted source
Wolfgang Sommer via Scopus - Elsevier

Methylation of OPRL1 mediates the effect of psychosocial stress on binge drinking in adolescents.

Journal of child psychology and psychiatry, and allied disciplines
2017-12-02 | Journal article
DOI: 10.1111/jcpp.12843
PMID: 29197086
Source: Self-asserted source
Wolfgang Sommer
grade
Preferred source (of 2)‎

Oxytocin Reduces Alcohol Cue-Reactivity in Alcohol-Dependent Rats and Humans.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology
2017-11-01 | Journal article
DOI: 10.1038/npp.2017.257
PMID: 29090683
PMC: PMC5916348
Source: Self-asserted source
Wolfgang Sommer

Low μ-Opioid Receptor Status in Alcohol Dependence Identified by Combined Positron Emission Tomography and Post-Mortem Brain Analysis

Neuropsychopharmacology
2017-02-11 | Journal article
DOI: 10.1038/npp.2016.145
Contributors: Derik Hermann; Natalie Hirth; Matthias Reimold; Anil Batra; Michael N Smolka; Sabine Hoffmann; Falk Kiefer; Hamid R Noori; Wolfgang H Sommer; Gerald Reischl et al.
Source: check_circle
Crossref

A gene-by-sex interaction for nicotine reward: Evidence from humanized mice and epidemiology

Translational Psychiatry
2016 | Journal article
DOI: 10.1038/tp.2016.132
EID:

2-s2.0-85028381306
Contributors: Bernardi, R.E.; Zohsel, K.; Hirth, N.; Treutlein, J.; Heilig, M.; Laucht, M.; Spanagel, R.; Sommer, W.H.
Source: Self-asserted source
Wolfgang Sommer via Scopus - Elsevier

A translational systems biology approach in both animals and humans identifies a functionally related module of accumbal genes involved in the regulation of reward processing and binge drinking in males

Journal of Psychiatry and Neuroscience
2016 | Journal article
DOI: 10.1503/jpn.150138
EID:

2-s2.0-84964733921
Contributors: Stacey, D.; Lourdusamy, A.; Ruggeri, B.; Maroteaux, M.; Jia, T.; Cattrell, A.; Nymberg, C.; Banaschewski, T.; Bhattacharyya, S.; Band, H. et al.
Source: Self-asserted source
Wolfgang Sommer via Scopus - Elsevier

Alcohol: Neurobiology of alcohol addiction

Neuroscience in the 21st Century: From Basic to Clinical, Second Edition
2016 | Book
DOI: 10.1007/978-1-4939-3474-4_107
EID:

2-s2.0-85018899740
Contributors: Spanagel, R.; Zink, M.; Sommer, W.H.
Source: Self-asserted source
Wolfgang Sommer via Scopus - Elsevier

Convergent evidence from alcohol-dependent humans and rats for a hyperdopaminergic state in protracted abstinence

Proceedings of the National Academy of Sciences of the United States of America
2016 | Journal article
DOI: 10.1073/pnas.1506012113
EID:

2-s2.0-84962512421
Contributors: Hirth, N.; Meinhardt, M.W.; Noori, H.R.; Salgado, H.; Torres-Ramirez, O.; Uhrig, S.; Broccoli, L.; Vengeliene, V.; Roßmanith, M.; Perreau-Lenz, S. et al.
Source: Self-asserted source
Wolfgang Sommer via Scopus - Elsevier

Modulation of nucleus accumbens connectivity by alcohol drinking and naltrexone in alcohol-preferring rats: A manganese-enhanced magnetic resonance imaging study

European Neuropsychopharmacology
2016 | Journal article
DOI: 10.1016/j.euroneuro.2016.01.003
EID:

2-s2.0-84956662322
Contributors: Dudek, M.; Canals, S.; Sommer, W.H.; Hyytiä, P.
Source: Self-asserted source
Wolfgang Sommer via Scopus - Elsevier
Items per page:
Page 1 of 4

Peer review (17 reviews for 6 publications/grants)

Review activity for Molecular psychiatry. (1)
Review activity for Nature communications (1)
Review activity for Neuropsychopharmacology. (9)
Review activity for Neuroscience and biobehavioral reviews. (2)
Review activity for Psychopharmacologia. (1)
Review activity for Translational psychiatry. (3)
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