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Employment (2)

Biocenter / University of Würzburg: Würzburg, DE

2002-04-01 to 2004-04-30 | Associate Professor (Institute for Physiological Chemistry)
Employment
Source: Self-asserted source
Christoph Englert

Institute of Genetics and Toxicology / KIT Campus North: Karlsruhe, DE

1995-05-08 to 2001-08-31 | Group leader
Employment
Source: Self-asserted source
Christoph Englert

Education and qualifications (1)

Max-Planck-Institut für Biochemie: Martinsried, Bayern, DE

1989-05-01 to 1992-09-30 | PhD
Education
Source: Self-asserted source
Christoph Englert

Funding (9)

The impact of mitochondria on aging and lifespan in the short-lived killifish Nothobranchius furzeri

Source: Self-asserted source
Christoph Englert via DimensionsWizard

Transport, processing and regulation of the Notch receptor

2010-01-01 to present | Grant
German Research Foundation (Bonn, DE)
URL: https://grants.uberresearch.com/501100001659/175797480/Transport-processing-and-regulation-of-the-Notch-receptor
GRANT_NUMBER: 175797480
Source: Self-asserted source
Christoph Englert via DimensionsWizard

Adressing the function of the Wilms tumor gene 1 (Wt1) by conditional inactivation in the mouse

Source: Self-asserted source
Christoph Englert via DimensionsWizard

Analysis of Wilms tumour gene 1 (wt1) regulation and function in zebrafish

Source: Self-asserted source
Christoph Englert via DimensionsWizard

Eya1 as a switch between signal transduction and transcription (C07)

2005-01-01 to 2008-12-31 | Grant
German Research Foundation (Bonn, DE)
URL: https://grants.uberresearch.com/501100001659/15027867/Eya1-as-a-switch-between-signal-transduction-and-transcription-C07
GRANT_NUMBER: 15027867
Source: Self-asserted source
Christoph Englert via DimensionsWizard

Identification and characterization of target genes of the tumor suppressor WT1 during gonad

Source: Self-asserted source
Christoph Englert via DimensionsWizard

In vivo characterization of different splice variants of Wilms tumor suppressor gene WT1

Source: Self-asserted source
Christoph Englert via DimensionsWizard

GRK 639:  The Molecular and Structural Basis of Tumorinstability

2000-01-01 to 2006-12-31 | Grant
German Research Foundation (Bonn, DE)
URL: https://grants.uberresearch.com/501100001659/273153/GRK-639-The-Molecular-and-Structural-Basis-of-Tumorinstability
GRANT_NUMBER: 273153
Source: Self-asserted source
Christoph Englert via DimensionsWizard

Functional characterization of Wilms` Tumorsuppressorgenprodukts, WT1, by producing transgenic mice with dominant negative WT1 alleles

Source: Self-asserted source
Christoph Englert via DimensionsWizard

Works (50 of 110)

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Page 1 of 3

Rapid Genotyping ofNothobranchius furzeriEmbryos, Larvae, and Adult Fish via High-Resolution Melt Analysis (HRMA)

Cold Spring Harbor Protocols
2023-08 | Journal article
DOI: 10.1101/pdb.prot107744
Contributors: Johannes Krug; Annekatrin Richter; Christoph Englert
Source: check_circle
Crossref

Generation of a transparent killifish line through multiplex CRISPR/Cas9mediated gene inactivation

eLife
2023-02-23 | Journal article
DOI: 10.7554/eLife.81549
Contributors: Johannes Krug; Birgit Perner; Carolin Albertz; Hanna Mörl; Vera L Hopfenmüller; Christoph Englert
Source: check_circle
Crossref

Non-aging despite high mutation rate – genomic insights into the evolution of Hydra

2022-07-05 | Preprint
DOI: 10.21203/rs.3.rs-1670825/v1
Contributors: Arne Sahm; Konstantin Riege; Marco Groth; Martin Bens; Johann Kraus; Martin Fischer; Hans Kestler; Christoph Englert; Ralf Schaible; Matthias Platzer et al.
Source: check_circle
Crossref

Generation of a transparent killifish line through multiplex CRISPR/Cas9-mediated gene inactivation

2022-07-04 | Preprint
DOI: 10.1101/2022.07.04.498720
Contributors: Johannes Krug; Carolin Albertz; Vera L. Hopfenmüller; Christoph Englert
Source: check_circle
Crossref

Aging Activates the Immune System and Alters the Regenerative Capacity in the Zebrafish Heart

Cells
2022-01 | Journal article | Author
DOI: 10.3390/cells11030345
Contributors: Hanna Reuter; Birgit Perner; Florian Wahl; Luise Rohde; Philipp Koch; Marco Groth; Katrin Buder; Christoph Englert
Source: check_circle
Multidisciplinary Digital Publishing Institute
grade
Preferred source (of 2)‎

Systems Analysis Reveals Ageing-Related Perturbations in Retinoids and Sex Hormones in Alzheimer’s and Parkinson’s Diseases

Biomedicines
2021-09-24 | Journal article
DOI: 10.3390/biomedicines9101310
Contributors: Simon Lam; Nils Hartmann; Rui Benfeitas; Cheng Zhang; Muhammad Arif; Hasan Turkez; Mathias Uhlén; Christoph Englert; Robert Knight; Adil Mardinoglu
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Wt1 positive neurons in the hindbrain are essential for respiration

2019-12-20 | Preprint
DOI: 10.1101/2019.12.20.884361
Contributors: Danny Schnerwitzki; Christian Hayn; Birgit Perner; Christoph Englert
Source: check_circle
Crossref

Zebrafish Wtx is a negative regulator of Wnt signaling but is dispensable for embryonic development and organ homeostasis

Developmental Dynamics
2019-09 | Journal article
DOI: 10.1002/dvdy.84
Contributors: Andreas Große; Birgit Perner; Uta Naumann; Christoph Englert
Source: check_circle
Crossref

Temperature throws a developmental switch.

Proceedings of the National Academy of Sciences of the United States of America
2018-11 | Journal article
DOI: 10.1073/pnas.1818216115
PMID: 30487215
Contributors: Englert C
Source: Self-asserted source
Christoph Englert via Europe PubMed Central

Dispersion/reaggregation in early development of annual killifishes: Phylogenetic distribution and evolutionary significance of a unique feature

Developmental Biology
2018-10 | Journal article
DOI: 10.1016/j.ydbio.2018.07.015
Contributors: Benjamin Naumann; Christoph Englert
Source: check_circle
Crossref

Neuron-specific inactivation of Wt1 alters locomotion in mice and changes interneuron composition in the spinal cord.

Life science alliance
2018-08 | Journal article
DOI: 10.26508/lsa.201800106
PMID: 30456369
PMC: PMC6238623
Contributors: Schnerwitzki D; Perry S; Ivanova A; Caixeta FV; Cramer P; Günther S; Weber K; Tafreshiha A; Becker L; Vargas Panesso IL et al.
Source: Self-asserted source
Christoph Englert via Europe PubMed Central

Loss of Wilms tumor 1 protein is a marker for apoptosis in response to replicative stress in leukemic cells.

Archives of toxicology
2018-03 | Journal article
DOI: 10.1007/s00204-018-2202-3
PMID: 29589053
Contributors: Pons M; Reichardt CM; Hennig D; Nathan A; Kiweler N; Stocking C; Wichmann C; Christmann M; Butter F; Reichardt S et al.
Source: Self-asserted source
Christoph Englert via Europe PubMed Central

Wilms Tumor 1b defines a wound-specific sheath cell subpopulation associated with notochord repair.

eLife
2018-02 | Journal article
DOI: 10.7554/elife.30657
PMID: 29405914
PMC: PMC5811212
Contributors: Lopez-Baez JC; Simpson DJ; LLeras Forero L; Zeng Z; Brunsdon H; Salzano A; Brombin A; Wyatt C; Rybski W; Huitema LFA et al.
Source: Self-asserted source
Christoph Englert via Europe PubMed Central

Kidney regeneration in fish.

The International journal of developmental biology
2018-01 | Journal article
DOI: 10.1387/ijdb.170335ce
PMID: 29938754
Contributors: Bates T; Naumann U; Hoppe B; Englert C
Source: Self-asserted source
Christoph Englert via Europe PubMed Central

Transcriptomic alterations during ageing reflect the shift from cancer to degenerative diseases in the elderly.

Nature communications
2018-01 | Journal article
DOI: 10.1038/s41467-017-02395-2
PMID: 29382830
PMC: PMC5790807
Contributors: Aramillo Irizar P; Schäuble S; Esser D; Groth M; Frahm C; Priebe S; Baumgart M; Hartmann N; Marthandan S; Menzel U et al.
Source: Self-asserted source
Christoph Englert via Europe PubMed Central

Wilms Tumor 1bdefines a wound-specific sheath cell subpopulation associated with notochord repair

2017-08 | Other
DOI: 10.1101/172288
OTHER-ID:

PPR16154
Contributors: Lopez-Baez JC; Zeng Z; Rybski W; Huitema LFA; Brombin A; Dale RM; Kawakami K; Englert C; Schulte-Merker S; Hastie ND et al.
Source: Self-asserted source
Christoph Englert via Europe PubMed Central

The Wilms tumor protein Wt1 contributes to female fertility by regulating oviductal proteostasis.

Human molecular genetics
2017-05 | Journal article
DOI: 10.1093/hmg/ddx075
PMID: 28334862
PMC: PMC5411738
Source: Self-asserted source
Christoph Englert via Europe PubMed Central

Fluorescence-Activated Cell Sorting (FACS) Protocol for Podocyte Isolation in Adult Zebrafish.

Methods in molecular biology (Clifton, N.J.)
2016 | Journal article
DOI: 10.1007/978-1-4939-4023-3_12
PMID: 27417966
Source: Self-asserted source
Christoph Englert via Europe PubMed Central

Function and Regulation of the Wilms' Tumor Suppressor 1 (WT1) Gene in Fish.

Methods in molecular biology (Clifton, N.J.)
2016 | Journal article
DOI: 10.1007/978-1-4939-4023-3_10
PMID: 27417964
Source: Self-asserted source
Christoph Englert via Europe PubMed Central

Immunofluorescence Staining of Wt1 on Sections of Zebrafish Embryos and Larvae.

Methods in molecular biology (Clifton, N.J.)
2016 | Journal article
DOI: 10.1007/978-1-4939-4023-3_11
PMID: 27417965
Source: Self-asserted source
Christoph Englert via Europe PubMed Central

Nothobranchius furzeri: A Model for Aging Research and More.

Trends in genetics : TIG
2016-09 | Journal article
DOI: 10.1016/j.tig.2016.06.006
PMID: 27427533
Source: Self-asserted source
Christoph Englert via Europe PubMed Central

Analysis of Zebrafish Kidney Development with Time-lapse Imaging Using a Dissecting Microscope Equipped for Optical Sectioning.

Journal of visualized experiments : JoVE
2016-04 | Journal article
DOI: 10.3791/53921
PMID: 27078207
PMC: PMC4841363
Source: Self-asserted source
Christoph Englert via Europe PubMed Central

Longitudinal RNA-Seq Analysis of Vertebrate Aging Identifies Mitochondrial Complex I as a Small-Molecule-Sensitive Modifier of Lifespan.

Cell systems
2016-02 | Journal article
DOI: 10.1016/j.cels.2016.01.014
PMID: 27135165
Source: Self-asserted source
Christoph Englert via Europe PubMed Central

MiR-21 is required for efficient kidney regeneration in fish.

BMC developmental biology
2015 | Journal article
DOI: 10.1186/s12861-015-0089-2
PMID: 26577279
PMC: PMC4650918
Source: Self-asserted source
Christoph Englert via Europe PubMed Central

Branched-chain amino acid catabolism is a conserved regulator of physiological ageing.

Nature communications
2015-12 | Journal article
DOI: 10.1038/ncomms10043
PMID: 26620638
PMC: PMC4686672
Source: Self-asserted source
Christoph Englert via Europe PubMed Central

Insights into Sex Chromosome Evolution and Aging from the Genome of a Short-Lived Fish.

Cell
2015-12 | Journal article
DOI: 10.1016/j.cell.2015.10.071
PMID: 26638077
Source: Self-asserted source
Christoph Englert via Europe PubMed Central

Age-dependent decline in fin regenerative capacity in the short-lived fish Nothobranchius furzeri.

Aging cell
2015-10 | Journal article
DOI: 10.1111/acel.12367
PMID: 26121607
PMC: PMC4568973
Source: Self-asserted source
Christoph Englert via Europe PubMed Central

Towards an understanding of kidney diseases associated with WT1 mutations.

Kidney international
2015-10 | Journal article
DOI: 10.1038/ki.2015.198
PMID: 26154924
PMC: PMC4687464
Source: Self-asserted source
Christoph Englert via Europe PubMed Central

Integration of Cistromic and Transcriptomic Analyses Identifies Nphs2, Mafb, and Magi2 as Wilms' Tumor 1 Target Genes in Podocyte Differentiation and Maintenance.

Journal of the American Society of Nephrology : JASN
2015-09 | Journal article
DOI: 10.1681/asn.2014080819
PMID: 25556170
PMC: PMC4552121
Source: Self-asserted source
Christoph Englert via Europe PubMed Central

BOR-syndrome-associated Eya1 mutations lead to enhanced proteasomal degradation of Eya1 protein.

PloS one
2014 | Journal article
DOI: 10.1371/journal.pone.0087407
PMID: 24489909
PMC: PMC3906160
Source: Self-asserted source
Christoph Englert via Europe PubMed Central

Alternative splicing of Wilms tumor suppressor 1 (Wt1) exon 4 results in protein isoforms with different functions.

Developmental biology
2014-09 | Journal article
DOI: 10.1016/j.ydbio.2014.06.026
PMID: 25014653
Source: Self-asserted source
Christoph Englert via Europe PubMed Central

Physiological state co-regulates thousands of mammalian mRNA splicing events at tandem splice sites and alternative exons.

Nucleic acids research
2014-08 | Journal article
DOI: 10.1093/nar/gku532
PMID: 25030907
PMC: PMC4132704
Source: Self-asserted source
Christoph Englert via Europe PubMed Central

The Wilms' tumor suppressor WT1 enhances CD95L expression and promotes activation-induced cell death in leukemic T cells.

International journal of cancer
2014-01 | Journal article
DOI: 10.1002/ijc.28379
PMID: 23832418
Source: Self-asserted source
Christoph Englert via Europe PubMed Central

LMX1B is essential for the maintenance of differentiated podocytes in adult kidneys.

Journal of the American Society of Nephrology : JASN
2013-11 | Journal article
DOI: 10.1681/asn.2012080788
PMID: 23990680
PMC: PMC3810075
Source: Self-asserted source
Christoph Englert via Europe PubMed Central

Focal segmental glomerulosclerosis is induced by microRNA-193a and its downregulation of WT1.

Nature medicine
2013-04 | Journal article
DOI: 10.1038/nm.3142
PMID: 23502960
Source: Self-asserted source
Christoph Englert via Europe PubMed Central

Absence of replicative senescence in cultured cells from the short-lived killifish Nothobranchius furzeri.

Experimental gerontology
2013-01 | Journal article
DOI: 10.1016/j.exger.2012.02.012
PMID: 22445733
Source: Self-asserted source
Christoph Englert via Europe PubMed Central

Ciliated sensory hair cell formation and function require the F-BAR protein syndapin I and the WH2 domain-based actin nucleator Cobl.

Journal of cell science
2013-01 | Journal article
DOI: 10.1242/jcs.111674
PMID: 23203810
Source: Self-asserted source
Christoph Englert via Europe PubMed Central

Kcnh1 voltage-gated potassium channels are essential for early zebrafish development.

The Journal of Biological Chemistry
2012-10 | Journal article
DOI: 10.1074/jbc.m112.363978
PMID: 22927438
PMC: PMC3471731
Source: Self-asserted source
Christoph Englert via Europe PubMed Central

A microinjection protocol for the generation of transgenic killifish (Species: Nothobranchius furzeri).

Developmental dynamics : an official publication of the American Association of Anatomists
2012-06 | Journal article
DOI: 10.1002/dvdy.23789
PMID: 22473915
Source: Self-asserted source
Christoph Englert via Europe PubMed Central

Mapping of quantitative trait loci controlling lifespan in the short-lived fish Nothobranchius furzeri--a new vertebrate model for age research.

Aging cell
2012-04 | Journal article
DOI: 10.1111/j.1474-9726.2011.00780.x
PMID: 22221414
PMC: PMC3437503
Source: Self-asserted source
Christoph Englert via Europe PubMed Central

Mitochondrial DNA copy number and function decrease with age in the short-lived fish Nothobranchius furzeri.

Aging cell
2011-10 | Journal article
DOI: 10.1111/j.1474-9726.2011.00723.x
PMID: 21624037
Source: Self-asserted source
Christoph Englert via Europe PubMed Central

Identification of adult nephron progenitors capable of kidney regeneration in zebrafish.

Nature
2011-02 | Journal article
DOI: 10.1038/nature09669
PMID: 21270795
PMC: PMC3170921
Source: Self-asserted source
Christoph Englert via Europe PubMed Central

Cofilin-1 inactivation leads to proteinuria--studies in zebrafish, mice and humans.

PloS one
2010 | Journal article
DOI: 10.1371/journal.pone.0012626
PMID: 20838616
PMC: PMC2935884
Source: Self-asserted source
Christoph Englert via Europe PubMed Central

Gender separation increases somatic growth in females but does not affect lifespan in Nothobranchius furzeri.

PloS one
2010 | Journal article
DOI: 10.1371/journal.pone.0011958
PMID: 20689818
PMC: PMC2914755
Source: Self-asserted source
Christoph Englert via Europe PubMed Central

Sipl1 and Rbck1 are novel Eya1-binding proteins with a role in craniofacial development.

Molecular and cellular biology
2010-12 | Journal article
DOI: 10.1128/mcb.01645-09
PMID: 20956555
PMC: PMC3004267
Source: Self-asserted source
Christoph Englert via Europe PubMed Central

Characterization of mesonephric development and regeneration using transgenic zebrafish.

American journal of physiology. Renal physiology
2010-11 | Journal article
DOI: 10.1152/ajprenal.00394.2010
PMID: 20810610
PMC: PMC2980409
Source: Self-asserted source
Christoph Englert via Europe PubMed Central

The small RNA expression profile of the developing murine urinary and reproductive systems.

FEBS letters
2010-11 | Journal article
DOI: 10.1016/j.febslet.2010.09.050
PMID: 20933514
Source: Self-asserted source
Christoph Englert via Europe PubMed Central

An unusual peptide from Conus villepinii: synthesis, solution structure, and cardioactivity.

Peptides
2010-07 | Journal article
DOI: 10.1016/j.peptides.2010.04.002
PMID: 20385188
Source: Self-asserted source
Christoph Englert via Europe PubMed Central

A novel Wilms tumor 1 (WT1) target gene negatively regulates the WNT signaling pathway.

The Journal of biological chemistry
2010-05 | Journal article
DOI: 10.1074/jbc.m109.094334
PMID: 20220130
PMC: PMC2863207
Source: Self-asserted source
Christoph Englert via Europe PubMed Central

Wt1 and retinoic acid signaling in the subcoelomic mesenchyme control the development of the pleuropericardial membranes and the sinus horns.

Circulation research
2010-04 | Journal article
DOI: 10.1161/circresaha.110.217455
PMID: 20185795
PMC: PMC2862253
Source: Self-asserted source
Christoph Englert via Europe PubMed Central
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Peer review (2 reviews for 2 publications/grants)

Review activity for Communications biology. (1)
Review activity for Nature aging. (1)
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