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Scopus Author ID: 55767360500
ResearcherID: N-3805-2014
Loop profile: 240790

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Employment (5)

University of Nottingham: Nottingham, Nottingham, GB

2019-10-07 to present | Nottingham Research Fellow (School of Chemistry)
Employment
Source: Self-asserted source
Ellis C. O'Neill

University of Oxford: Oxford, Oxfordshire, GB

2016-10-02 to 2019-10-01 | Glasstone Research Fellow (Department of Plant Sciences)
Employment
Source: Self-asserted source
Ellis C. O'Neill

University of Oxford: Oxford, Oxfordshire, GB

2015-01-12 to 2016-10-01 | Postdoctoral Research Assistant (Department of Plant Sciences)
Employment
Source: Self-asserted source
Ellis C. O'Neill

University of California San Diego Scripps Institution of Oceanography: La Jolla, CA, US

2014-01-02 to 2015-01-01 | Postdoctoral Scholar (CMBB)
Employment
Source: Self-asserted source
Ellis C. O'Neill

John Innes Centre: Norwich, Norfolk, GB

2013-10-01 to 2013-12-31 | PostDoctoral researcher (Biological Chemsitry)
Employment
Source: Self-asserted source
Ellis C. O'Neill

Education and qualifications (2)

John Innes Centre: Norwich, Norfolk, GB

2009-10 to 2013-09 | PhD (Biological Chemistry)
Education
Source: Self-asserted source
Ellis C. O'Neill

University of Cambridge: Cambridge, Cambridgeshire, GB

2006-09 to 2009-07 | MA (Plant Sciences)
Education
Source: Self-asserted source
Ellis C. O'Neill

Professional activities (3)

Royal Society of Chemistry: London, London, GB

Membership
Source: Self-asserted source
Ellis C. O'Neill

Biochemical Society: London, London, GB

Membership
Source: Self-asserted source
Ellis C. O'Neill

Biotechnology and Biological Sciences Research Council: Swindon, GB

2023 to present | Panel Member (Advanced Manufacturing and Clean Growth Strategic Advisory Panel)
Invited position
Source: Self-asserted source
Ellis C. O'Neill

Funding (9)

Investigating biosynthesis of the newly discovered natural product euglenatide and distribution across the breadth of Euglenoid algae

2024-01-01 to 2024-12-31 | Grant
Engineering and Physical Sciences Research Council (Swindon, GB)
URL: https://app.dimensions.ai/details/grant/grant.13905484
GRANT_NUMBER: EP/Y003314/1
Source: Self-asserted source
Ellis C. O'Neill via DimensionsWizard

A chemistry-first approach to uncovering novel natural products from a proprietary strain collection of rare and unexplored bacteria

2023-10-01 to 2027-09-30 | Grant
Biotechnology and Biological Sciences Research Council (Swindon, GB)
URL: https://app.dimensions.ai/details/grant/grant.13886294
GRANT_NUMBER: 2886339
Source: Self-asserted source
Ellis C. O'Neill via DimensionsWizard

A synthetic biology platform for sustainable, climate-friendly conversion of CO2 to products using cyanobacteria

2022-10-01 to 2026-09-30 | Grant
Biotechnology and Biological Sciences Research Council (Swindon, GB)
URL: https://app.dimensions.ai/details/grant/grant.13028342
GRANT_NUMBER: 2746407
Source: Self-asserted source
Ellis C. O'Neill via DimensionsWizard

Combinatorial metabolic engineering platform for the production of valuable compounds in the alga Euglena gracilis

2022-10-01 to 2026-09-30 | Grant
Biotechnology and Biological Sciences Research Council (Swindon, GB)
URL: https://app.dimensions.ai/details/grant/grant.13028237
GRANT_NUMBER: 2746116
Source: Self-asserted source
Ellis C. O'Neill via DimensionsWizard

Developing the Alga Euglena Gracilis as a Source of Vegan Omega Oils and Other High Value Compounds

2022-10-01 to 2026-09-30 | Grant
Biotechnology and Biological Sciences Research Council (Swindon, GB)
URL: https://app.dimensions.ai/details/grant/grant.13026060
GRANT_NUMBER: 2748026
Source: Self-asserted source
Ellis C. O'Neill via DimensionsWizard

Polyurethane-degrading enzymes: Structural analysis and development

2020-10-01 to 2024-09-30 | Grant
Engineering and Physical Sciences Research Council (Swindon, GB)
URL: https://app.dimensions.ai/details/grant/grant.9469948
GRANT_NUMBER: 2445458
Source: Self-asserted source
Ellis C. O'Neill via DimensionsWizard

Novel Natural Products in Algae: an Untapped Resource for New Chemistry, Biochemistry and Bioactivity

2020-10-01 to 2024-03-31 | Grant
Engineering and Physical Sciences Research Council (Swindon, GB)
URL: https://app.dimensions.ai/details/grant/grant.9642677
GRANT_NUMBER: 2508483
Source: Self-asserted source
Ellis C. O'Neill via DimensionsWizard

Nottingham Research Fellowship

2019-10 to present | Award
University Of Nottingham (Nottingham, GB)
Source: Self-asserted source
Ellis C. O'Neill

Glasstone Research Fellowship

2016-10 to 2019-10 | Grant
University Of Oxford (Oxford, GB)
Source: Self-asserted source
Ellis C. O'Neill

Works (43)

Advances in euglenoid genomics: unravelling the fascinating biology of a complex clade

Trends in Genetics
2025-03 | Journal article
DOI: 10.1016/j.tig.2024.07.007
Contributors: Oskar Fields; Michael J. Hammond; Xiao Xu; Ellis C. O’Neill
Source: check_circle
Crossref

Strategies for producing high value small molecules in microalgae

Plant Physiology and Biochemistry
2024-09 | Journal article
DOI: 10.1016/j.plaphy.2024.108942
Contributors: Michael H. Cagney; Ellis C. O'Neill
Source: check_circle
Crossref

Glycosylated proteins in the protozoan alga Euglena gracilis: a proteomic approach

FEMS Microbiology Letters
2023-01-17 | Journal article
DOI: 10.1093/femsle/fnac120
Contributors: Ellis C O’Neill
Source: check_circle
Crossref

Euglena International Network (EIN): Driving euglenoid biotechnology for the benefit of a challenged world

Biology Open
2022-11-01 | Journal article
DOI: 10.1242/bio.059561
Contributors: ThankGod Echezona Ebenezer; Ross S. Low; Ellis Charles O'Neill; Ishuo Huang; Antonio DeSimone; Scott C. Farrow; Robert A. Field; Michael L. Ginger; Sergio Adrián Guerrero; Michael Hammond et al.
Source: check_circle
Crossref

Glycosylated proteins identified for the first time in the alga Euglena gracilis

2021-10-28 | Preprint
DOI: 10.1101/2021.10.28.466288
Contributors: Ellis O’Neill
Source: check_circle
Crossref

A community resource for paired genomic and metabolomic data mining.

Nature chemical biology
2021-04 | Journal article
DOI: 10.1038/s41589-020-00724-z
PMID: 33589842
PMC: PMC7987574
Contributors: Schorn MA; Verhoeven S; Ridder L; Huber F; Acharya DD; Aksenov AA; Aleti G; Moghaddam JA; Aron AT; Aziz S et al.
Source: Self-asserted source
Ellis C. O'Neill via Europe PubMed Central
grade
Preferred source (of 2)‎

Using new techniques to study old favorites: A case study of Euglena

Handbook of Algal Science, Technology and Medicine
2020 | Book chapter
DOI: 10.1016/b978-0-12-818305-2.00010-3
Part of ISBN: 9780128183052
Source: Self-asserted source
Ellis C. O'Neill

Mining Natural Product Biosynthesis in Eukaryotic Algae

Marine Drugs
2020-01-30 | Journal article
DOI: 10.3390/md18020090
Part of ISSN: 1660-3397
Source: Self-asserted source
Ellis C. O'Neill
grade
Preferred source (of 2)‎

Euglena Central Metabolic Pathways and Their Subcellular Locations

Metabolites
2019-06-14 | Journal article
DOI: 10.3390/metabo9060115
Contributors: Sahutchai Inwongwan; Nicholas J. Kruger; R. George Ratcliffe; Ellis C. O’Neill
Source: check_circle
Crossref
grade
Preferred source (of 3)‎

Targeted antibiotic discovery through biosynthesis-associated resistance determinants: target directed genome mining

Critical Reviews in Microbiology
2019-05-04 | Journal article
DOI: 10.1080/1040841X.2019.1590307
Contributors: Ellis C. O’Neill; Michelle Schorn; Charles B. Larson; Natalie Millán-Aguiñaga
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Proteome of the secondary plastid of <em>Euglena gracilis</em> reveals metabolic quirks and colourful history

2019-03-20 | Other
DOI: 10.1242/prelights.9503
Contributors: Ellis O'Neill
Source: check_circle
Crossref

Transcriptome, proteome and draft genome of Euglena gracilis

2019-02-09 | Journal article
DOI: 10.1186/s12915-019-0626-8
Part of ISSN: 1741-7007
Source: Self-asserted source
Ellis C. O'Neill
grade
Preferred source (of 2)‎

Insights into toxic Prymnesium parvum blooms: the role of sugars and algal viruses

2018-04-17 | Journal article
DOI: 10.1042/bst20170393
Part of ISSN: 0300-5127
Part of ISSN: 1470-8752
Source: Self-asserted source
Ellis C. O'Neill
grade
Preferred source (of 2)‎

13C LABELLING FOR METABOLIC FLUX ANALYSIS IN HETEROTROPHIC EUGLENA GRACILIS

Phycologia
2017 | Journal article
WOSUID: WOS:000412892000175
Source: check_circle
Web of Science Researcher Profile Sync

Biomolecular Engineering of Microorganisms for Natural Products Production

Reference Module in Chemistry, Molecular Sciences and Chemical Engineering
2017 | Other
DOI: 10.1016/b978-0-12-409547-2.12791-x
Contributors: E.C. O’Neill
Source: Self-asserted source
Ellis C. O'Neill via Crossref Metadata Search
grade
Preferred source (of 2)‎

Prioritizing Natural Product Diversity in a Collection of 146 Bacterial Strains Based on Growth and Extraction Protocols

Journal of Natural Products
2017 | Journal article
DOI: 10.1021/ACSJNATPROD.6B00722
WOSUID: WOS:000397695100003
Contributors: Crusemann, Max; O'Neill, Ellis C.; Larson, Charles B.; Melnik, Alexey V.; Floros, Dimitrios J.; da Silva, Ricardo R.; Jensen, Paul R.; Dorrestein, Pieter C.; Moore, Bradley S.
Source: check_circle
Web of Science Researcher Profile Sync

Exploring the Glycans of <em>Euglena gracilis</em>

2017-12-17 | Other
DOI: 10.20944/preprints201711.0051.v2
Contributors: Ellis C. O'Neill; Sakonwan Kuhaudomlarp; Martin Rejzek; Jonatan U. Fangel; Kathirvel Alagesan; Daniel Kolarich; William G. T. Willats; Robert A. Field
Source: check_circle
Crossref

Exploring the Glycans of Euglena gracilis

Biology
2017-12-15 | Journal article
DOI: 10.3390/biology6040045
DOI: 10.20944/preprints201711.0051.v1
Part of ISSN: 2079-7737
Source: Self-asserted source
Ellis C. O'Neill
grade
Preferred source (of 5)‎

An Alternative Strategy for Trypanosome Survival in the Mammalian Bloodstream Revealed through Genome and Transcriptome Analysis of the Ubiquitous Bovine Parasite Trypanosoma (Megatrypanum) theileri

Genome Biology and Evolution
2017-08 | Journal article
DOI: 10.1093/gbe/evx152
Part of ISSN: 1759-6653
Contributors: Steven Kelly; Alasdair Ivens; G. Adam Mott; Ellis O’Neill; David Emms; Olivia Macleod; Paul Voorheis; Kevin Tyler; Matthew Clark; Jacqueline Matthews et al.
Source: Self-asserted source
Ellis C. O'Neill via Crossref Metadata Search
grade
Preferred source (of 2)‎

Cellodextrin phosphorylase from Ruminiclostridium thermocellum : X-ray crystal structure and substrate specificity analysis

Carbohydrate Research
2017-07 | Journal article
DOI: 10.1016/j.carres.2017.07.005
Contributors: Ellis C. O'Neill; Giulia Pergolizzi; Clare E.M. Stevenson; David M. Lawson; Sergey A. Nepogodiev; Robert A. Field
Source: Self-asserted source
Ellis C. O'Neill via Crossref Metadata Search
grade
Preferred source (of 2)‎

Fluorescent mannosides serve as acceptor substrates for glycosyltransferase and sugar-1-phosphate transferase activities in Euglena gracilis membranes.

2017-01 | Journal article
DOI: 10.1016/j.carres.2016.11.017
PMID: 27960097
PMC: PMC5240791
Contributors: Ivanova IM; Nepogodiev SA; Saalbach G; O'Neill EC; Urbaniak MD; Ferguson MA; Gurcha SS; Besra GS; Field RA
Source: Self-asserted source
Ellis C. O'Neill via Europe PubMed Central
grade
Preferred source (of 2)‎

Prioritizing Natural Product Diversity in a Collection of 146 Bacterial Strains Based on Growth and Extraction Protocols

Journal of Natural Products
2016-11-11 | Journal article
DOI: 10.1021/acs.jnatprod.6b00722
Source: Self-asserted source
Ellis C. O'Neill

Engineering biosynthesis of high-value compounds in photosynthetic organisms

Critical Reviews in Biotechnology
2016-10-04 | Journal article
DOI: 10.1080/07388551.2016.1237467
Source: Self-asserted source
Ellis C. O'Neill
grade
Preferred source (of 4)‎

Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking

Nat Biotechnol
2016-08-09 | Journal article
DOI: 10.1038/nbt.3597
Contributors: Mingxun Wang; Jeremy J Carver; Vanessa V Phelan; Laura M Sanchez; Neha Garg; Yao Peng; Don Duy Nguyen; Jeramie Watrous; Clifford A Kapono; Tal Luzzatto-Knaan et al.
Source: Self-asserted source
Ellis C. O'Neill via Crossref Metadata Search
grade
Preferred source (of 2)‎

Gene Discovery for Synthetic Biology: Exploring the Novel Natural Product Biosynthetic Capacity of Eukaryotic Microalgae

Methods in Enzymology
2016-04-05 | Journal article
DOI: 10.1016/bs.mie.2016.03.005
Source: Self-asserted source
Ellis C. O'Neill
grade
Preferred source (of 2)‎

Crystal structure of a novel two domain GH78 family α-rhamnosidase from Klebsiella oxytoca with rhamnose bound

Proteins: Structure, Function, and Bioinformatics
2015 | Journal article
DOI: 10.1002/prot.24807
Contributors: O'Neill, Ellis C.; Stevenson, Clare E. M.; Paterson, Michael J.; Rejzek, Martin; Chauvin, Anne-Laure; Lawson, David M.; Field, Robert A.
Source: Self-asserted source
Ellis C. O'Neill via ResearcherID
grade
Preferred source (of 2)‎

Discovery of fatty acid synthase inhibitors and their biosynthetic pathways by a novel target-directed genome mining strategy

Planta Medica
2015 | Journal article
DOI: 10.1055/S-0035-1556168
WOSUID: WOS:000359967000084
Contributors: Li, J.; Tang, X.; Zhang, J. J.; O'Neill, E. C.; Mantovani, S. M.; Moore, B. S.
Source: check_circle
Web of Science Researcher Profile Sync

Discovery of fatty acid synthase inhibitors and their biosynthetic pathways by a novel target-directed genome mining strategy

Planta Medica
2015 | Journal article
DOI: 10.1055/S-0035-1556330
WOSUID: WOS:000359967000246
Contributors: Li, J.; Tang, X.; Zhang, J. J.; O'Neill, E. C.; Mantovani, S. M.; Moore, B. S.
Source: check_circle
Web of Science Researcher Profile Sync

Enzymatic synthesis of nucleobase-modified UDP-sugars: Scope and limitations

2015 | Journal article
DOI: 10.1016/j.carres.2014.12.005
EID:

2-s2.0-84922656988
Contributors: Wagstaff, B.A.; Rejzek, M.; Pesnot, T.; Tedaldi, L.M.; Caputi, L.; O'Neill, E.C.; Benini, S.; Wagner, G.K.; Field, R.A.
Source: Self-asserted source
Ellis C. O'Neill via Scopus - Elsevier
grade
Preferred source (of 2)‎

Identification of Thiotetronic Acid Antibiotic Biosynthetic Pathways by Target-directed Genome Mining

ACS Chemical Biology
2015 | Journal article
DOI: 10.1021/ACSCHEMBIO.5B00658
WOSUID: WOS:000366875400019
Contributors: Tang, Xiaoyu; Li, Jie; Millan-Aguinaga, Natalie; Zhang, Jia Jia; O'Neill, Ellis C.; Ugalde, Juan A.; Jensen, Paul R.; Mantovani, Simone M.; Moore, Bradley S.
Source: check_circle
Web of Science Researcher Profile Sync

Structural Dissection of the Maltodextrin Disproportionation Cycle of the Arabidopsis Plastidial Disproportionating Enzyme 1 (DPE1)

Journal of Biological Chemistry
2015 | Journal article
DOI: 10.1074/JBC.M115.682245
WOSUID: WOS:000366614700018
Contributors: O'Neill, Ellis C.; Stevenson, Clare E. M.; Tantanarat, Krit; Latousakis, Dimitrios; Donaldson, Matthew I.; Rejzek, Martin; Nepogodiev, Sergey A.; Limpaseni, Tipaporn; Field, Robert A.; Lawson, David M.
Source: check_circle
Web of Science Researcher Profile Sync

The transcriptome of Euglena gracilis reveals unexpected metabolic capabilities for carbohydrate and natural product biochemistry

Molecular BioSystems
2015 | Journal article
DOI: 10.1039/C5MB00319A
Contributors: O'Neill, Ellis C.; Trick, Martin; Hill, Lionel; Rejzek, Martin; Dusi, Renata G.; Hamilton, Chris J.; Zimba, Paul V.; Henrissat, Bernard; Field, Robert A.
Source: Self-asserted source
Ellis C. O'Neill via ResearcherID
grade
Preferred source (of 3)‎

Underpinning Starch Biology with in vitro Studies on Carbohydrate-Active Enzymes and Biosynthetic Glycomaterials.

2015 | Journal article
DOI: 10.3389/fbioe.2015.00136
PMID: 26442250
PMC: PMC4561517
Contributors: O'Neill EC; Field RA
Source: Self-asserted source
Ellis C. O'Neill via Europe PubMed Central
grade
Preferred source (of 2)‎

Identification of Thiotetronic Acid Antibiotic Biosynthetic Pathways by Target-directed Genome Mining.

2015-10 | Journal article
PMID: 26458099
Contributors: Tang X; Li J; Millán-Aguiñaga N; Zhang JJ; O'Neill EC; Ugalde JA; Jensen PR; Mantovani SM; Moore BS
Source: Self-asserted source
Ellis C. O'Neill via Europe PubMed Central

Structural Dissection of the Maltodextrin Disproportionation Cycle of the Arabidopsis Plastidial Enzyme DPE1.

2015-10 | Journal article
PMID: 26504082
Contributors: O'Neill EC; Stevenson CE; Tantanarat K; Latousakis D; Donaldson MI; Rejzek M; Nepogodiev SA; Limpaseni T; Field RA; Lawson DM
Source: Self-asserted source
Ellis C. O'Neill via Europe PubMed Central
grade
Preferred source (of 2)‎

Euglena in time: Evolution, control of central metabolic processes and multi-domain proteins in carbohydrate and natural product biochemistry

Perspectives in Science
2015-10-23 | Journal article
DOI: 10.1016/j.pisc.2015.07.002
Source: Self-asserted source
Ellis C. O'Neill
grade
Preferred source (of 2)‎

Enzymatic synthesis using glycoside phosphorylases

2014 | Journal article
DOI: 10.1016/j.carres.2014.06.010
EID:

2-s2.0-84904273576
Contributors: O'Neill, E.C.; Field, R.A.
Source: Self-asserted source
Ellis C. O'Neill via Scopus - Elsevier
grade
Preferred source (of 2)‎

Expression and characterization of 4-α-glucanotransferase genes from Manihot esculenta Crantz and Arabidopsis thaliana and their use for the production of cycloamyloses

2014 | Journal article
DOI: 10.1016/j.procbio.2013.10.009
EID:

2-s2.0-84891826789
Contributors: Tantanarat, K.; O'Neill, E.C.; Rejzek, M.; Field, R.A.; Limpaseni, T.
Source: Self-asserted source
Ellis C. O'Neill via Scopus - Elsevier
grade
Preferred source (of 3)‎

Sugar-coated sensor chip and nanoparticle surfaces for the in vitro enzymatic synthesis of starch-like materials

Chemical Science
2014 | Journal article
DOI: 10.1039/c3sc51829a
Contributors: O'Neill, Ellis C.; Rashid, Abdul M.; Stevenson, Clare E. M.; Hetru, Anne-Claire; Gunning, A. Patrick; Rejzek, Martin; Nepogodiev, Sergey A.; Bornemann, Stephen; Lawson, David M.; Field, Robert A.
Source: Self-asserted source
Ellis C. O'Neill via ResearcherID
grade
Preferred source (of 3)‎

A one-pot enzymatic approach to the O-fluoroglucoside of N-methylanthranilate.

2013 | Journal article
DOI: 10.1016/j.bmc.2013.05.057
Contributors: Caputi L; Field RA; Hill L; Louveau T; O'Neill EC; Osbourn A; Rejzek M
Source: Self-asserted source
Ellis C. O'Neill via ResearcherID
grade
Preferred source (of 3)‎

Antibiotics: Blocking bacterial defences.

2013-08 | Journal article
DOI: 10.1038/nchem.1718
PMID: 23881489
Contributors: Field RA; O'Neill EC
Source: Self-asserted source
Ellis C. O'Neill via Europe PubMed Central
grade
Preferred source (of 3)‎

An expedient enzymatic route to isomeric 2-, 3- and 6-monodeoxy-monofluoro- maltose derivatives

2012 | Journal article
DOI: 10.1016/j.carres.2012.05.026
EID:

2-s2.0-84865050325
Contributors: Tantanarat, K.; Rejzek, M.; O'Neill, E.; Ruzanski, C.; Hill, L.; Fairhurst, S.A.; Limpaseni, T.; Field, R.A.
Source: Self-asserted source
Ellis C. O'Neill via Scopus - Elsevier
grade
Preferred source (of 2)‎

<em>Euglena</em> Central Metabolic Pathways and Their Subcellular Locations
Source: check_circle
Multidisciplinary Digital Publishing Institute
grade
Preferred source (of 2)‎

Peer review (33 reviews for 19 publications/grants)

Review activity for ACS chemical biology. (1)
Review activity for Algal research. (3)
Review activity for Biochimie. (1)
Review activity for Biology open (2)
Review activity for Biotechnology reports. (2)
Review activity for BMC genomics (6)
Review activity for Carbohydrate polymers. (2)
Review activity for Carbohydrate research. (3)
Review activity for Catalysts. (2)
Review activity for Environmental science & technology. (1)
Review activity for Journal of agricultural and food chemistry. (1)
Review activity for Journal of applied phycology. (1)
Review activity for Journal of phycology. (2)
Review activity for Nucleic acids research. (1)
Review activity for Plant science. (1)
Review activity for Planta. (1)
Review activity for PloS one. (1)
Review activity for Scientific reports. (1)
Review activity for Water. (1)
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