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United Kingdom

Activities

Employment (2)

University of Cambridge: Cambridge, GB

2024-04-15 to present
Employment
Source: Self-asserted source
Sarah Teichmann

Wellcome Sanger Institute: Cambridge, Cambridgeshire, GB

2024-04-14 (Cellular Genetics)
Employment
Source: Self-asserted source
Sarah Teichmann

Education and qualifications (1)

MRC Laboratory of Molecular Biology: Cambridge, Cambridgeshire, GB

1996-10-01 to 2000-09-30 | Ph.D
Qualification
Source: Self-asserted source
Sarah Teichmann

Professional activities (1)

Canadian Institute for Advanced Research: ON, ON, CA

2023-04-17 to 2028-04-17 | Co-Director (Research Program: The Multiscale Human)
Invited position
Source: Self-asserted source
Sarah Teichmann

Funding (1)

Mapping Cells and Interactions in the Thymus Across Development and Aging

Source: Self-asserted source
Sarah Teichmann

Works (50 of 182)

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Page 1 of 4

multiDGD: A versatile deep generative model for multi-omics data

Nature Communications
2024-11-20 | Journal article
Contributors: Viktoria Schuster; Emma Dann; Anders Krogh; Sarah A. Teichmann
Source: check_circle
Crossref

The Human Cell Atlas from a cell census to a unified foundation model

Nature
2024-11-20 | Journal article
Contributors: Jennifer E. Rood; Samantha Wynne; Lucia Robson; Anna Hupalowska; John Randell; Sarah A. Teichmann; Aviv Regev
Source: check_circle
Crossref

Author Correction: A physical wiring diagram for the human immune system

Nature
2024-11-07 | Journal article
Contributors: Jarrod Shilts; Yannik Severin; Francis Galaway; Nicole MĂĽller-Sienerth; Zheng-Shan Chong; Sophie Pritchard; Sarah Teichmann; Roser Vento-Tormo; Berend Snijder; Gavin J. Wright
Source: check_circle
Crossref

Spatial genomics: mapping human steatotic liver disease

Nature Reviews Gastroenterology & Hepatology
2024-09 | Journal article
Contributors: Kylie P. Matchett; Jasmin Paris; Sarah A. Teichmann; Neil C. Henderson
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Crossref

Bin2cell reconstructs cells from high resolution Visium HD data

Bioinformatics
2024-09-02 | Journal article
Contributors: Krzysztof Polański; Raquel Bartolomé-Casado; Ioannis Sarropoulos; Chuan Xu; Nick England; Frode L Jahnsen; Sarah A Teichmann; Nadav Yayon; Anthony Mathelier
Source: check_circle
Crossref

Pan-cancer profiling of tumor-infiltrating natural killer cells through transcriptional reference mapping

Nature Immunology
2024-08 | Journal article
Contributors: Herman Netskar; Aline Pfefferle; Jodie P. Goodridge; Ebba Sohlberg; Olli Dufva; Sarah A. Teichmann; Demi Brownlie; Jakob Michaëlsson; Nicole Marquardt; Trevor Clancy et al.
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Crossref

Molecular connectomics: Placing cells into morphological tissue context

PLOS Biology
2024-08-26 | Journal article
Contributors: Stathis Megas; Nadav Yayon; Kerstin B. Meyer; Sarah A. Teichmann
Source: check_circle
Crossref

Protein Condensate Atlas from predictive models of heteromolecular condensate composition

Nature Communications
2024-07-10 | Journal article
Contributors: Kadi L. Saar; Rob M. Scrutton; Kotryna Bloznelyte; Alexey S. Morgunov; Lydia L. Good; Alpha A. Lee; Sarah A. Teichmann; Tuomas P. J. Knowles
Source: check_circle
Crossref

Multi-modal generative modeling for joint analysis of single-cell T cell receptor and gene expression data

Nature Communications
2024-07-03 | Journal article
Contributors: Felix Drost; Yang An; Irene Bonafonte-PardĂ s; Lisa M. Dratva; Rik G. H. Lindeboom; Muzlifah Haniffa; Sarah A. Teichmann; Fabian Theis; Mohammad Lotfollahi; Benjamin Schubert
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Crossref

Bin2cell reconstructs cells from high resolution Visium HD data

2024-06-22 | Preprint
Contributors: Krzysztof Polański; Raquel Bartolomé-Casado; Ioannis Sarropoulos; Chuan Xu; Nick England; Frode L. Jahnsen; Sarah A. Teichmann; Nadav Yayon
Source: check_circle
Crossref

Revisiting Cardiac Biology in the Era of Single Cell and Spatial Omics

Circulation Research
2024-06-07 | Journal article
Contributors: Jack A. Palmer; Nadia Rosenthal; Sarah A. Teichmann; Monika Litvinukova
Source: check_circle
Crossref

Immune microniches shape intestinal Treg function

Nature
2024-04-25 | Journal article
Contributors: Yisu Gu; Raquel Bartolomé-Casado; Chuan Xu; Alice Bertocchi; Alina Janney; Cornelia Heuberger; Claire F. Pearson; Sarah A. Teichmann; Emily E. Thornton; Fiona Powrie
Source: check_circle
Crossref

Estimating the impact of single-cell RNA sequencing of human tissues on drug target validation

2024-04-05 | Preprint
Contributors: Emma Dann; Erin Teeple; Rasa Elmentaite; Kerstin B Meyer; Giorgio Gaglia; Frank Nestle; Virginia Savova; Emanuele de Rinaldis; Sarah A Teichmann
Source: check_circle
Crossref

Human BioMolecular Atlas Program (HuBMAP): 3D Human Reference Atlas Construction and Usage

2024-04-02 | Preprint
Contributors: Katy Börner; Philip D. Blood; Jonathan C. Silverstein; Matthew Ruffalo; Rahul Satija; Sarah A. Teichmann; Gloria Pryhuber; Ravi S. Misra; Jeffrey Purkerson; Jean Fan et al.
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Crossref

Challenges and perspectives in computational deconvolution of genomics data

Nature Methods
2024-03 | Journal article
Contributors: Lana X. Garmire; Yijun Li; Qianhui Huang; Chuan Xu; Sarah A. Teichmann; Naftali Kaminski; Matteo Pellegrini; Quan Nguyen; Andrew E. Teschendorff
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Crossref

Characterizing Different Modes of Interplay Between Rap1 and H3 Using Inducible H3-depletion Yeast

Journal of Molecular Biology
2023-12 | Journal article
Contributors: Peerapat Khamwachirapithak; David Guillaume-Schoepfer; Pakkanan Chansongkrow; Sarah A Teichmann; Philip A Wigge; Varodom Charoensawan
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Crossref

How developmental cell atlases inform stem cell embryo models

Nature Methods
2023-12 | Journal article
Contributors: Muzlifah Haniffa; Aidan Maartens; Sarah A. Teichmann
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Crossref

Quantification of absolute transcription factor binding affinities in the native chromatin context using BANC-seq

Nature Biotechnology
2023-12 | Journal article
Contributors: Hannah K. Neikes; Katarzyna W. Kliza; Cathrin Gräwe; Roelof A. Wester; Pascal W. T. C. Jansen; Lieke A. Lamers; Marijke P. Baltissen; Simon J. van Heeringen; Colin Logie; Sarah A. Teichmann et al.
Source: check_circle
Crossref

Precise identification of cell states altered in disease using healthy single-cell references

Nature Genetics
2023-11 | Journal article
Contributors: Emma Dann; Ana-Maria Cujba; Amanda J. Oliver; Kerstin B. Meyer; Sarah A. Teichmann; John C. Marioni
Source: check_circle
Crossref

multiDGD: A versatile deep generative model for multi-omics data

2023-08-23 | Preprint
Contributors: Viktoria Schuster; Emma Dann; Anders Krogh; Sarah A. Teichmann
Source: check_circle
Crossref

Single-cell transcriptomics for the assessment of cardiac disease

Nature Reviews Cardiology
2023-05 | Journal article
Contributors: Antonio M. A. Miranda; Vaibhao Janbandhu; Henrike Maatz; Kazumasa Kanemaru; James Cranley; Sarah A. Teichmann; Norbert HĂĽbner; Michael D. Schneider; Richard P. Harvey; Michela Noseda
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Crossref

CLICK- chemoproteomics and molecular dynamics simulation reveals pregnenolone targets and their binding conformations in Th2 cells

2023-05-24 | Preprint
Contributors: Sougata Roy; Sudeep Roy; Bidesh Mahata; Jhuma Pramanik; Marco L. Hennrich; Anne-Claude Gavin; Sarah A. Teichmann
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Crossref

Gene-level alignment of single cell trajectories informs the progression ofin vitroT cell differentiation

2023-03-10 | Preprint
Contributors: Dinithi Sumanaweera; Chenqu Suo; Daniele Muraro; Emma Dann; Krzysztof Polanski; Alexander S. Steemers; Jong-Eun Park; Bianca Dumitrascu; Sarah A. Teichmann
Source: check_circle
Crossref

scMoMaT jointly performs single cell mosaic integration and multi-modal bio-marker detection

Nature Communications
2023-01-24 | Journal article
Contributors: Ziqi Zhang; Haoran Sun; Ragunathan Mariappan; Xi Chen; Xinyu Chen; Mika S. Jain; Mirjana Efremova; Sarah A. Teichmann; Vaibhav Rajan; Xiuwei Zhang
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Crossref

Impact of the Human Cell Atlas on medicine

Nature Medicine
2022-12 | Journal article
Contributors: Jennifer E. Rood; Aidan Maartens; Anna Hupalowska; Sarah A. Teichmann; Aviv Regev
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Crossref

Transcriptional signals of dedifferentiation in human cancer

2022-11-28 | Preprint
Contributors: Gerda Kildisiute; Maria Kalyva; Rasa Elmentaite; Stijn van Dongen; Christine Thevanesan; Alice Piapi; Kirsty Ambridge; Elena Prigmore; Muzlifah Haniffa; Sarah A. Teichmann et al.
Source: check_circle
Crossref

Identification of visual cortex cell types and species differences using single-cell RNA sequencing

Nature Communications
2022-11-12 | Journal article
Contributors: Jia-Ru Wei; Zhao-Zhe Hao; Chuan Xu; Mengyao Huang; Lei Tang; Nana Xu; Ruifeng Liu; Yuhui Shen; Sarah A. Teichmann; Zhichao Miao et al.
Source: check_circle
Crossref

Precise identification of cell states altered in disease with healthy single-cell references

2022-11-10 | Preprint
Contributors: Emma Dann; Sarah A. Teichmann; John C. Marioni
Source: check_circle
Crossref

scMoMaT: a unified framework for single cell mosaic integration and multi-modal bio-marker detection

2022-09-13 | Preprint
Contributors: Ziqi Zhang; Haoran Sun; Ragunathan Mariappan; Xi Chen; Xinyu Chen; Mika Sarkin Jain; Mirjana Efremova; Sarah Teichmann; Vaibhav Rajan; Xiuwei Zhang
Source: check_circle
Crossref

A physical wiring diagram for the human immune system

Nature
2022-08-11 | Journal article
Contributors: Jarrod Shilts; Yannik Severin; Francis Galaway; Nicole MĂĽller-Sienerth; Zheng-Shan Chong; Sophie Pritchard; Sarah Teichmann; Roser Vento-Tormo; Berend Snijder; Gavin J. Wright
Source: check_circle
Crossref

Single-cell atlases: shared and tissue-specific cell types across human organs

Nature Reviews Genetics
2022-07 | Journal article
Contributors: Rasa Elmentaite; Cecilia DomĂ­nguez Conde; Lu Yang; Sarah A. Teichmann
Source: check_circle
Crossref

Community voices: policy proposals to promote inclusion in academia through the lens of women in science

Nature Communications
2022-07-13 | Journal article
Contributors: Sarah A. Teichmann; Muzlifah Haniffa; Jasmin Fisher
Source: check_circle
Crossref

Differential abundance testing on single-cell data using k-nearest neighbor graphs

Nature Biotechnology
2022-02 | Journal article
Contributors: Emma Dann; Neil C. Henderson; Sarah A. Teichmann; Michael D. Morgan; John C. Marioni
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Crossref

An organoid CRISPRi screen revealed that SOX9 primes human fetal lung tip progenitors to receive WNT and RTK signals

2022-01-27 | Preprint
Contributors: Dawei Sun; Oriol Llora Batlle; Jelle van den Ameele; John C. Thomas; Peng He; Kyungtae Lim; Walfred Tang; Chufan Xu; Kerstin B. Meyer; Sarah A. Teichmann et al.
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Crossref

Completing the cancer jigsaw puzzle with single-cell multiomics

Nature Cancer
2021-12-21 | Journal article
Contributors: Song Chen; Sarah A. Teichmann
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Crossref

Anatomical structures, cell types and biomarkers of the Human Reference Atlas

Nature Cell Biology
2021-11 | Journal article
Contributors: Katy Börner; Sarah A. Teichmann; Ellen M. Quardokus; James C. Gee; Kristen Browne; David Osumi-Sutherland; Bruce W. Herr, II; Andreas Bueckle; Hrishikesh Paul; Muzlifah Haniffa et al.
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Crossref

Cell type ontologies of the Human Cell Atlas

Nature Cell Biology
2021-11 | Journal article
Contributors: David Osumi-Sutherland; Chuan Xu; Maria Keays; Adam P. Levine; Peter V. Kharchenko; Aviv Regev; Ed Lein; Sarah A. Teichmann
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Crossref

High-throughput full-length single-cell RNA-seq automation

Nature Protocols
2021-06 | Journal article
Contributors: Lira Mamanova; Zhichao Miao; Ayesha Jinat; Peter Ellis; Lesley Shirley; Sarah A. Teichmann
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Crossref

Acquisition of alveolar fate and differentiation competence by human fetal lung epithelial progenitor cells

2021-06-30 | Other
Contributors: Kyungtae Lim; Walfred Tang; Dawei Sun; Peng He; Sarah A. Teichmann; John C. Marioni; Kerstin B. Meyer; Emma L. Rawlins
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Crossref

Integrating T-cell receptor and transcriptome for large-scale single-cell immune profiling analysis

2021-06-25 | Preprint
Contributors: Felix Drost; Yang An; Lisa M Dratva; Rik GH Lindeboom; Muzlifah Haniffa; Sarah A Teichmann; Fabian Theis; Mohammad Lotfollahi; Benjamin Schubert
Source: check_circle
Crossref

Anatomical Structures, Cell Types, and Biomarkers Tables Plus 3D Reference Organs in Support of a Human Reference Atlas

2021-06-01 | Other
Contributors: Katy Börner; Sarah A. Teichmann; Ellen M. Quardokus; James Gee; Kristen Browne; David Osumi-Sutherland; Bruce W. Herr, II; Andreas Bueckle; Hrishikesh Paul; Muzlifah A. Haniffa et al.
Source: check_circle
Crossref

In vivo negative regulation of SARS-CoV-2 receptor, ACE2, by interferons and its genetic control [version 1; peer review: 1 approved with reservations]

2021-03-03 | Journal article
Part of ISSN: 2398-502X
Contributors: M. Azim Ansari; Emanuele Marchi; Narayan Ramamurthy; Dominik Aschenbrenner; Sophie Morgan; Carl-Philipp Hackstein; STOP-HCV consortium; ISARIC-4C Investigators; Shang-Kuan Lin; Rory Bowden et al.
Source: check_circle
Wellcome Open Research

INSIGHT: A population-scale COVID-19 testing strategy combining point-of-care diagnosis with centralized high-throughput sequencing

Science Advances
2021-02-12 | Journal article
Contributors: Qianxin Wu; Chenqu Suo; Tom Brown; Tengyao Wang; Sarah A. Teichmann; Andrew R. Bassett
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Crossref

Single-cell analysis of human B cell maturation predicts how antibody class switching shapes selection dynamics

Science Immunology
2021-02-12 | Journal article
Contributors: Hamish W. King; Nara Orban; John C. Riches; Andrew J. Clear; Gary Warnes; Sarah A. Teichmann; Louisa K. James
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Crossref

Milo:differential abundance testing on single-cell data using k-NN graphs

2020-11-23 | Preprint
Contributors: Emma Dann; Neil C. Henderson; Sarah A. Teichmann; Michael D. Morgan; John C. Marioni
Source: check_circle
Crossref

The network effect: studying COVID-19 pathology with the Human Cell Atlas

Nature Reviews Molecular Cell Biology
2020-08-30 | Journal article
Contributors: Sarah Teichmann; Aviv Regev
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Crossref

Mosquito cellular immunity at single-cell resolution

Science
2020-08-28 | Journal article
Contributors: Gianmarco Raddi; Ana Beatriz F. Barletta; Mirjana Efremova; Jose Luis Ramirez; Rafael Cantera; Sarah A. Teichmann; Carolina Barillas-Mury; Oliver Billker
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Crossref

Single cell transcriptomics comes of age

Nature Communications
2020-08-27 | Journal article
Contributors: Sarah Aldridge; Sarah A. Teichmann
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Crossref

Putative cell type discovery from single-cell gene expression data

Nature Methods
2020-06-18 | Journal article
Contributors: Zhichao Miao; Pablo Moreno; Ni Huang; Irene Papatheodorou; Alvis Brazma; Sarah A. Teichmann
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Crossref

INSIGHT: a population scale COVID-19 testing strategy combining point-of-care diagnosis with centralised high-throughput sequencing

2020-06-02 | Preprint
Contributors: Qianxin Wu; Chenqu Suo; Tom Brown; Tengyao Wang; Sarah A. Teichmann; Andrew R. Bassett
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Crossref
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