Personal information

Emails & domains

Verified email domains

Other IDs

ResearcherID: I-5904-2017
Scopus Author ID: 8987296100

Activities

Collapse all

Employment (1)

Charles University, First Faculty of Medicine: Prague , CZ

(Institute of Pharmacology)
Employment
Source: Self-asserted source
Nikolina Kutinová Canová

Works (49)

Simple, streamlined, cost-effective cDNA synthesis method from cell cultures

Open Biology
2025-03 | Journal article
DOI: 10.1098/rsob.240226
Contributors: Daniel Stránský; Monika Šteigerová; Markéta Kuklová; Veronika Hanzíková; Nikolina Canová; Jiří Novotný; Ladislav Šenolt; Ondřej Slanař
Source: check_circle
Crossref

Effects of celastrol on the heart and liver galaninergic system expression in a mouse model of Western-type diet-induced obesity and metabolic dysfunction-associated steatotic liver disease and steatohepatitis

Frontiers in Pharmacology
2025-02-04 | Journal article
DOI: 10.3389/fphar.2025.1476994
Part of ISSN: 1663-9812
Contributors: Nikolina Canová; Jana Šípková; Mahak Arora; Zuzana Pavlíková; Tomáš Kučera; Ondřej Šeda; Tijana Šopin; Tomáš Vacík; Ondřej Slanař
Source: Self-asserted source
Nikolina Kutinová Canová

mTOR as an eligible molecular target for possible pharmacological treatment of nonalcoholic steatohepatitis

European Journal of Pharmacology
2022-04 | Journal article
DOI: 10.1016/j.ejphar.2022.174857
Contributors: Mahak Arora; Nikolina Kutinová Canová; Hassan Farghali
Source: check_circle
Crossref

SIRT1 Modulators in Experimentally Induced Liver Injury

Oxidative Medicine and Cellular Longevity
2019-06-02 | Journal article
DOI: 10.1155/2019/8765954
Contributors: Hassan Farghali; Mighty Kgalalelo Kemelo; Nikolina Kutinová Canová
Source: check_circle
Crossref

The involvement of sirtuin 1 and heme oxygenase 1 in the hepatoprotective effects of quercetin against carbon tetrachloride-induced sub-chronic liver toxicity in rats

Chemico-Biological Interactions
2017 | Journal article
DOI: 10.1016/j.cbi.2017.03.014
EID:

2-s2.0-85016146558
Contributors: Kemelo, M.K.; Pierzynová, A.; Kutinová Canová, N.; Kučera, T.; Farghali, H.
Source: Self-asserted source
Nikolina Kutinová Canová via Scopus - Elsevier

Comparative effects of Quercetin and SRT1720 against D-galactosamine/lipopolysaccharide-induced hepatotoxicity in rats: biochemical and molecular biological investigations

European Review For Medical and Pharmacological Sciences
2016 | Journal article
WOSUID:

WOS:000371305200028
Contributors: Kemelo, M. K.; Horinek, A.; Canova, N. K.; Farghali, H.
Source: Self-asserted source
Nikolina Kutinová Canová via ResearcherID

Comparative effects of Quercetin and SRT1720 against D-galactosamine/lipopolysaccharideinduced hepatotoxicity in rats: Biochemical and molecular biological investigations

European Review for Medical and Pharmacological Sciences
2016 | Journal article
EID:

2-s2.0-84981523389
Contributors: Kemelo, M.K.; Horinek, A.; Canová, N.K.; Farghali, H.
Source: Self-asserted source
Nikolina Kutinová Canová via Scopus - Elsevier

In vitro and in vivo experimental hepatotoxic models in liver research: Applications to the assessment of potential hepatoprotective drugs

Physiological Research
2016 | Journal article
EID:

2-s2.0-85009961415
Contributors: Farghali, H.; Kgalalelo Kemelo, M.; Wojnarová, L.; Kutinová Canová, N.
Source: Self-asserted source
Nikolina Kutinová Canová via Scopus - Elsevier

In Vitro and In Vivo Experimental Hepatotoxic Models in Liver Research: Applications to the Assessment of Potential Hepatoprotective Drugs

Physiological Research
2016 | Journal article
WOSUID:

WOS:000392029200002
Contributors: Farghali, H.; Kemelo, M. Kgalalelo; Wojnarova, L.; Canova, N. Kutinova
Source: Self-asserted source
Nikolina Kutinová Canová via ResearcherID

Hepatoprotective properties of extensively studied medicinal plant active constituents: Possible common mechanisms

Pharmaceutical Biology
2015 | Journal article
DOI: 10.3109/13880209.2014.950387
WOSUID:

WOS:000352077600001
Contributors: Farghali, Hassan; Canova, Nikolina Kutinova; Zakhari, Samir
Source: Self-asserted source
Nikolina Kutinová Canová via ResearcherID
grade
Preferred source (of 2)‎

Sirtuin 1 modulation in rat model of acetaminophen-induced hepatotoxicity

Physiological Research
2015 | Journal article
EID:

2-s2.0-84983119746
Contributors: Wojnarová, L.; Kutinová Canová, N.; Farghali, H.; Kučera, T.
Source: Self-asserted source
Nikolina Kutinová Canová via Scopus - Elsevier

Sirtuin 1 Modulation in Rat Model of Acetaminophen-Induced Hepatotoxicity

Physiological Research
2015 | Journal article
WOSUID:

WOS:000367548600006
Contributors: Wojnarova, L.; Canova, N. Kutinova; Farghali, H.; Kucera, T.
Source: Self-asserted source
Nikolina Kutinová Canová via ResearcherID

D-galactosamine/lipopolysaccharide-induced hepatotoxicity downregulates sirtuin 1 in rat liver: Role of sirtuin 1 modulation in hepatoprotection

Physiological Research
2014 | Journal article
EID:

2-s2.0-84920008183
Contributors: Kemelo, M.K.; Wojnarová, L.; Kutinová Canová, N.; Farghali, H.
Source: Self-asserted source
Nikolina Kutinová Canová via Scopus - Elsevier

D-Galactosamine/Lipopolysaccharide-Induced Hepatotoxicity Downregulates Sirtuin 1 in Rat Liver: Role of Sirtuin 1 Modulation in Hepatoprotection

Physiological Research
2014 | Journal article
WOSUID:

WOS:000345590100012
Contributors: Kemelo, M. K.; Wojnarova, L.; Canova, N. Kutinova; Farghali, H.
Source: Self-asserted source
Nikolina Kutinová Canová via ResearcherID

New findings on the role of calcium-sensing receptor in the treatment of bone and mineral homeostasis disorders | Nové poznatky o úloze calcium-sensing receptoru při léčbě poruch kostní a minerálové homeostázy

Klinicka Farmakologie a Farmacie
2014 | Journal article
EID:

2-s2.0-84892605718
Contributors: Kameníková, L.; Canová, N.K.; Farghali, H.
Source: Self-asserted source
Nikolina Kutinová Canová via Scopus - Elsevier

Potential interactions between drugs and dietary supplements | Potenciální interakce mezi léčivy a doplnky stravy rostlinného původu

Casopis Lekaru Ceskych
2014 | Journal article
EID:

2-s2.0-84900525543
Contributors: Farghali, H.; Kameníková, L.; Hodis, J.; Canová, N.K.
Source: Self-asserted source
Nikolina Kutinová Canová via Scopus - Elsevier

Allosteric Binding Sites as Molecular Targets in Development, Design and Action of Drugs

Chemicke Listy
2013 | Journal article
WOSUID:

WOS:000324159500002
Contributors: Farghali, Hassan; Canova, Nikolina Kutinova
Source: Self-asserted source
Nikolina Kutinová Canová via ResearcherID

Allosteric binding sites as molecular targets in development, design and action of drugs | Allosterická vazebná místa jako molekulární cíle pro vývoj, design a působení nových léčiv

Chemicke Listy
2013 | Journal article
EID:

2-s2.0-84879707215
Contributors: Farghali, H.; Kutinová Canová, N.
Source: Self-asserted source
Nikolina Kutinová Canová via Scopus - Elsevier

Resveratrol and related compounds as antioxidants with an allosteric mechanism of action in epigenetic drug targets

Physiological Research
2013 | Journal article
EID:

2-s2.0-84876045065
Contributors: Farghali, H.; Kutinová Canová, N.; Lekić, N.
Source: Self-asserted source
Nikolina Kutinová Canová via Scopus - Elsevier

Resveratrol and Related Compounds as Antioxidants With an Allosteric Mechanism of Action in Epigenetic Drug Targets

Physiological Research
2013 | Journal article
WOSUID:

WOS:000317958500002
Contributors: Farghali, H.; Canova, N. Kutinova; Lekic, N.
Source: Self-asserted source
Nikolina Kutinová Canová via ResearcherID

The involvement of heme oxygenase 1 but not nitric oxide synthase 2 in a hepatoprotective action of quercetin in lipopolysaccharide-induced hepatotoxicity of D-galactosamine sensitized rats

Fitoterapia
2013 | Journal article
DOI: 10.1016/j.fitote.2013.03.016
WOSUID:

WOS:000319953100004
Contributors: Lekic, Natasa; Canova, Nikolina Kutinova; Horinek, Ales; Farghali, Hassan
Source: Self-asserted source
Nikolina Kutinová Canová via ResearcherID
grade
Preferred source (of 2)‎

Cryopreservation of precision cut tissue slices (PCTS): Investigation of morphology and reactivity

Experimental and Toxicologic Pathology
2011 | Journal article
DOI: 10.1016/j.etp.2010.04.010
WOSUID:

WOS:000294695000009
Contributors: Kasper, Hans-Udo; Konze, Elisabeth; Canova, Nikolina Kutinova; Dienes, Hans Peter; Dries, Volker
Source: Self-asserted source
Nikolina Kutinová Canová via ResearcherID
grade
Preferred source (of 2)‎

Effects of resveratrol pretreatment on tert-butylhydroperoxide induced hepatocyte toxicity in immobilized perifused hepatocytes: Involvement of inducible nitric oxide synthase and hemoxygenase-1

Nitric Oxide-Biology and Chemistry
2009 | Journal article
DOI: 10.1016/j.niox.2008.08.006
WOSUID:

WOS:000261231600001
Contributors: Cerny, Dalibor; Canova, Nikolina Kutinova; Martinek, Jindrich; Horinek, Ales; Kmonickova, Eva; Zidek, Zdenek; Farghali, Hassan
Source: Self-asserted source
Nikolina Kutinová Canová via ResearcherID
grade
Preferred source (of 2)‎

Glucose release as a response to glucagon in rat hepatocyte culture: Involvement of NO signaling

Physiological Research
2008 | Journal article
EID:

2-s2.0-50449100657
Contributors: Farghali, H.; Hodis, J.; Kutinová-Canová, N.; Potměšil, P.; Kmoníčková, E.; Zídek, Z.
Source: Self-asserted source
Nikolina Kutinová Canová via Scopus - Elsevier

Glucose release as a response to glucagon in rat hepatocyte culture: Involvement of NO signaling

Physiological Research
2008 | Journal article
WOSUID:

WOS:000259157300010
Contributors: Farghali, H.; Hodis, J.; Kutinova-Canova, N.; Potmesil, P.; Kmonickova, E.; Zidek, Z.
Source: Self-asserted source
Nikolina Kutinová Canová via ResearcherID

Modulation of spontaneous and lipopolysaccharide-induced nitric oxide production and apoptosis by d-galactosamine in rat hepatocyte culture: The significance of combinations of different methods

Toxicology Mechanisms and Methods
2008 | Journal article
DOI: 10.1080/15376510701738421
WOSUID:

WOS:000252580100008
Contributors: Canova, Nikolina Kutinova; Martinek, Jindrich; Kmonickova, Eva; Zidek, Zdenek; Kamenikova, Ludmila; Farghali, Hassan
Source: Self-asserted source
Nikolina Kutinová Canová via ResearcherID
grade
Preferred source (of 2)‎

Protective activity of resveratrol on tert-butylhydrperoxide and D-galactosamine induced heptocyte apoptosis and necrosis in vitro and in vivo

Journal of Hepatology
2008 | Journal article
DOI: 10.1016/S0168-8278(08)60427-4
WOSUID:

WOS:000256683200424
Contributors: Farghali, H.; Cerny, D.; Canova, N. Kutinova; Martinek, J.
Source: Self-asserted source
Nikolina Kutinová Canová via ResearcherID

Caspase-3 and other markers in hepatocyte apoptotic and necrotic studies

Chemicke Listy
2007 | Journal article
EID:

2-s2.0-38349120722
Contributors: Černý, D.; Stiaková, Z.; Kmoníčková, E.; Zídek, Z.; Canová, N.K.; Farghali, H.
Source: Self-asserted source
Nikolina Kutinová Canová via Scopus - Elsevier

Thapsigargin, a selective inhibitor of sarco-endoplasmic reticulum Ca2+-ATPases, modulates nitric oxide production and cell death of primary rat hepatocytes in culture

Cell Biology and Toxicology
2007 | Journal article
DOI: 10.1007/s10565-007-0185-6
WOSUID:

WOS:000247725800004
Contributors: Canova, N. Kutinova; Kmonickova, E.; Martinek, J.; Zidek, Z.; Farghali, H.
Source: Self-asserted source
Nikolina Kutinová Canová via ResearcherID
grade
Preferred source (of 2)‎

The role of adrenergic agonists on glycogenolysis in rat hepatocyte cultures and possible involvement of NO

Physiological Research
2007 | Journal article
EID:

2-s2.0-35648973685
Contributors: Hodis, J.; Kutinová-Canová, N.; Potměšil, P.; Kameníková, L.; Kmoníčková, E.; Zídek, Z.; Farghali, H.
Source: Self-asserted source
Nikolina Kutinová Canová via Scopus - Elsevier

The role of adrenergic agonists on glycogenolysis in rat hepatocyte cultures and possible involvement of NO

Physiological Research
2007 | Journal article
WOSUID:

WOS:000249415500006
Contributors: Hodis, J.; Kutinova-Canova, N.; Potmesil, P.; Kamenikova, L.; Kmonickova, E.; Zidek, Z.; Farghali, H.
Source: Self-asserted source
Nikolina Kutinová Canová via ResearcherID

An increase in intracellular free calcium induced by thapsigargin modulates nitric oxide production and apoptotic injury in rat hepatocytes

Journal of Hepatology
2006 | Journal article
WOSUID:

WOS:000237328100294
Contributors: Canova, N. Kutinova; Kmonickova, E.; Zidek, Z.; Martinek, J.; Farghali, H.
Source: Self-asserted source
Nikolina Kutinová Canová via ResearcherID

Nitric oxide production from rat adipocytes is modulated by beta(3)-adrenergic receptor agonists and is involved in a cyclic AMP-dependent lipolysis in adipocytes

Nitric Oxide-Biology and Chemistry
2006 | Journal article
DOI: 10.1016/j.niox.2005.06.006
WOSUID:

WOS:000237043300002
Contributors: Canova, NK; Lincova, D; Kmonickova, E; Kamenikova, L; Farghali, H
Source: Self-asserted source
Nikolina Kutinová Canová via ResearcherID
grade
Preferred source (of 2)‎

The effect of lipopolysaccharide and tumor necrosis factor alpha on D-galactosamine-induced apoptosis in rat hepatocyte culture

Acta Pharmacologica Sinica
2006 | Journal article
WOSUID:

WOS:000239590003150
Contributors: Farghali, H.; Canova, N. Kutinova; Martinek, J.; Kmonikova, E.; Zidek, Z.
Source: Self-asserted source
Nikolina Kutinová Canová via ResearcherID

The morphological and immunocytochemical evaluation of primary rat hepatocytes undergoing spontaneous cell death: modulation by the nitric oxide donor S-nitroso-N-acetylpenicillamine.

Biomedical papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia
2006 | Journal article
EID:

2-s2.0-36048962678
Contributors: Kucera, T.; Canova, N.K.; Farghali, H.; Martinek, J.
Source: Self-asserted source
Nikolina Kutinová Canová via Scopus - Elsevier

Inconsistent effect of nitric oxide on lipolysis in isolated rat adipocytes

Physiological Research
2005 | Journal article
EID:

2-s2.0-24044543271
Contributors: Canová, N.; Lincová, D.; Farghali, H.
Source: Self-asserted source
Nikolina Kutinová Canová via Scopus - Elsevier

Inconsistent effect of nitric oxide on lipolysis in isolated rat adipocytes

Physiological Research
2005 | Journal article
WOSUID:

WOS:000231539100005
Contributors: Canova, N; Lincova, D; Farghali, H
Source: Self-asserted source
Nikolina Kutinová Canová via ResearcherID

Modulator of intracellular Ca(2+), thapsigargin, interferes with in vitro secretion of cytokines and nitric oxide.

Biomedical papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia
2005 | Journal article
EID:

2-s2.0-34250353645
Contributors: Kmonícková, E.; Canová, N.K.; Farghali, H.; Holý, A.; Zídek, Z.
Source: Self-asserted source
Nikolina Kutinová Canová via Scopus - Elsevier

Possible involvement of NO in beta3-adrenoceptor-camp dependent lipolysis in adipocytes

Atherosclerosis Supplements
2005 | Journal article
WOSUID:

WOS:000228739000122
Contributors: Farghali, H; Canova, N; Lincova, D
Source: Self-asserted source
Nikolina Kutinová Canová via ResearcherID

Endotoxin stimulates NOSII in apidocytes: Implications in lipolysis signalling

Toxicology and Applied Pharmacology
2004 | Journal article
WOSUID:

WOS:000222348900820
Contributors: Farghali, H; Lincova, D; Kamenikova, L; Gaier, N; Canova, N
Source: Self-asserted source
Nikolina Kutinová Canová via ResearcherID

Evaluation of a flat membrane hepatocyte bioreactor for pharmacotoxicological applications: Evidence that inhibition of spontaneously produced nitric oxide improves cell functionality

Atla-Alternatives To Laboratory Animals
2004 | Journal article
WOSUID:

WOS:000220916400018
Contributors: Canova, N; Kmonicova, E; Lincova, D; Vitek, L; Farghali, H
Source: Self-asserted source
Nikolina Kutinová Canová via ResearcherID

Evaluation of a Flat Membrane Hepatocyte Bioreactor for Pharmacotoxicological Applications: Evidence that Inhibition of Spontaneously Produced Nitric Oxide Improves Cell Functionality

ATLA Alternatives to Laboratory Animals
2004 | Journal article
EID:

2-s2.0-1942451939
Contributors: Canová, N.; Kmoníčková, E.; Lincová, D.; Vítek, L.; Farghali, H.
Source: Self-asserted source
Nikolina Kutinová Canová via Scopus - Elsevier

Nitric oxide synthase inhibitors modulate lipopolysaccharide-induced hepatocyte injury: dissociation between in vivo and in vitro effects

International Immunopharmacology
2003 | Journal article
DOI: 10.1016/S1567-5769(03)00185-1
WOSUID:

WOS:000186287800008
Contributors: Farghali, H; Canova, N; Kucera, T; Martinek, J; Masek, K
Source: Self-asserted source
Nikolina Kutinová Canová via ResearcherID
grade
Preferred source (of 2)‎

Effect of nitric oxide donors on isoprenaline-induced lipolysis in rat epididymal adipose tissue: Studies in isolated adipose tissues and immobilized perfused adipocytes

Physiological Research
2002 | Journal article
EID:

2-s2.0-0036408325
Contributors: Lincová, D.; Mišeková, D.; Kmoníčková, E.; Canová, N.; Farghali, H.
Source: Self-asserted source
Nikolina Kutinová Canová via Scopus - Elsevier

Effect of nitric oxide donors on isoprenaline-induced lipolysis in rat epididymal adipose tissue: Studies in isolated adipose tissues and immobilized perfused adipocytes

Physiological Research
2002 | Journal article
WOSUID:

WOS:000179140300009
Contributors: Lincova, D; Misekova, D; Kmonickova, E; Canova, N; Farghali, H
Source: Self-asserted source
Nikolina Kutinová Canová via ResearcherID

Evaluation of the functionality and cyclosporin A biotransformation in laboratory scale hepatocyte bioreactors

Journal of Hepatology
2002 | Journal article
WOSUID:

WOS:000175704700514
Contributors: Canova, N; Kmonickova, E; Lincova, D; Farghali, H
Source: Self-asserted source
Nikolina Kutinová Canová via ResearcherID

Inhibition of endotoxemia-induced nitric oxide synthase expression by cyclosporin A enhances hepatocyte injury in rats: amelioration by NO donors

International Immunopharmacology
2002 | Journal article
DOI: 10.1016/S1567-5769(01)00159-X
WOSUID:

WOS:000173019900011
Contributors: Farghali, H; Canova, N; Gaier, N; Lincova, D; Kmonickova, E; Strestikova, P; Masek, K
Source: Self-asserted source
Nikolina Kutinová Canová via ResearcherID
grade
Preferred source (of 2)‎

Urea synthesis and cyclosporin a biotransformation in a laboratory scale hepatocyte bioreactor model

Pharmacological Research
2002 | Journal article
DOI: 10.1016/S1043661802002347
WOSUID:

WOS:000179892000006
Contributors: Farghali, H; Lincova, D; Gaier, N; Kmoniekova, E; Kamenikova, L; Canova, N; Vitek, L
Source: Self-asserted source
Nikolina Kutinová Canová via ResearcherID
grade
Preferred source (of 2)‎

Inhibition of endotoxemia-induced nitric oxide synthase expression by cyclosporin A enhances hepatocyte injury in rat

Journal of Hepatology
2001 | Journal article
WOSUID:

WOS:000169243400711
Contributors: Farhali, H; Strestikova, P; Canova, N; Gaier, N; Lincova, D
Source: Self-asserted source
Nikolina Kutinová Canová via ResearcherID
How many people are using ORCID?