Sven Bergmann (0000-0002-6785-9034)

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Sven Bergmann heads the Computational Biology Group in the Department of Computational Biology at the University of Lausanne. He joined the Faculty of Biology and Medicine in 2005 as Assistant Professor and became Associate Professor in 2010 after successfully completing his tenure track. He is also affiliated with the Swiss Institute of Bioinformatics since 2006.
Sven studied theoretical particle physics with Prof. Yosef Nir at the Weizmann Institute of Science (Israel) where he received his PhD in 2001 for studies of neutrino oscillations and CP violation. He then joined the laboratory of Prof. Naama Barkai in the Department of Molecular Genetics at the same institute, where he first worked as a Koshland postdoctoral fellow and later as staff scientist.
His work in the field of computational biology includes designing and applying novel algorithms for the analysis of large-scale biological and medical data, as well as modeling of genetic networks pertaining to the development of the Drosophila embryo and the response of plants to environmental changes.

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Comparing tangible retinal image characteristics with deep learning features reveals their complementarity for gene association and disease prediction

2025-04-07 | Preprint

DOI: 10.21203/rs.3.rs-6130721/v1

Contributors: David Presby; Michael Beyeler; Olga Trofimova; Dennis Bontempi; Leah Bottger; Sacha Bors; Ilaria Iuliani; Ian Quintas; Sofia Ortin Vela; Sven Bergmann

Sven Bergmann

https://orcid.org/0000-0002-6785-9034

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Works (50 of 183)

Comparing tangible retinal image characteristics with deep learning features reveals their complementarity for gene association and disease prediction

Cross-organ Analysis Reveals Associations between Vascular Properties of the Retina, the Carotid and Aortic Artery, and the Brain

Genetic Insights from Automated Lumen Diameter Measurements in Carotid Ultrasounds of the UK Biobank

Cross-organ Analysis Reveals Associations between Vascular Properties of the Retina, the Carotid and Aortic Artery, and the Brain

Disentangling genetic effects on transcriptional and post-transcriptional gene regulation through integrating exon and intron expression QTLs

Estimating Quality of OCT Cubes using Phase-Level Unified Metric Evaluation (PLUME-OCT)

Phenotypic and Genetic Characteristics of Retinal Vascular Parameters and their Association with Diseases

Phenotypic and Genetic Characteristics of Retinal Vascular Parameters and their Association with Diseases

Disentangling genetic effects on transcriptional and post-transcriptional gene regulation through integrating exon and intron expression QTLs

Genome-wide Association Studies of Retinal Vessel Tortuosity Identify Numerous Novel Loci Revealing Genes and Pathways Associated With Ocular and Cardiometabolic Diseases.

Cross-GWAS coherence test at the gene and pathway level

Untargeted Metabolome- and Transcriptome-Wide Association Study Suggests Causal Genes Modulating Metabolite Concentrations in Urine.

Cross-GWAS coherence test at the gene and pathway level

Mechanical forces drive ordered patterning of hair cells in the mammalian inner ear

GWAS of retinal vessel tortuosity identifies 85 novel loci recovering variants associated with disease

Assessment of network module identification across complex diseases.

High capacity in G protein-coupled receptor signaling

cis-Acting Complex-Trait-Associated lincRNA Expression Correlates with Modulation of Chromosomal Architecture

Genome-Wide Association between Transcription Factor Expression and Chromatin Accessibility Reveals Regulators of Chromatin Accessibility

Rare and low-frequency coding variants alter human adult height

Metabomatching: Using genetic association to identify metabolites in proton NMR spectroscopy

Interoperable and scalable data analysis with microservices: Applications in Metabolomics

Genome-Wide Association between Transcription Factor Expression and Chromatin Accessibility Reveals Regulators of Chromatin Accessibility

A genome-wide association meta-analysis on apolipoprotein A-IV concentrations

A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape

Evidence for three genetic loci involved in both anorexia nervosa risk and variation of body mass index

Fast and rigorous computation of gene and pathway scores from SNP-based summary statistics

Genome-wide analysis identifies 12 loci influencing human reproductive behavior

Genome-wide analysis reveals novel regulators of growth in Drosophila melanogaster

Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels

RNAseq analysis of heart tissue from mice treated with atenolol and isoproterenol reveals a reciprocal transcriptional response

Tissue-specific regulatory circuits reveal variable modular perturbations across complex diseases

Genome-wide association between transcription factor expression and chromatin accessibility reveals chromatin state regulators

A genetic risk score combining 32 SNPs is associated with body mass index and improves obesity prediction in people with major depressive disorder

Genome-wide association studies identify genetic loci associated with albuminuria in diabetes

Genome-wide association study with targeted and non-targeted NMR metabolomics identifies 15 novel loci of urinary human metabolic individuality

Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair

Pom1 gradient buffering through intermolecular auto-phosphorylation

Sox4 participates in the modulation of Schwann cell myelination

The influence of age and sex on genetic associations with adult body size and shape: a large-scale genome-wide interaction study

The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

A higher mutational burden in females supports a “female protective model” in neurodevelopmental disorders

Defining the role of common variation in the genomic and biological architecture of adult human height

Distinct levels in Pom1 gradients limit Cdr2 activity and localization to time and position division

Fifteen years SIB Swiss Institute of Bioinformatics: life science databases, tools and support

Genome-wide association study of metabolic traits reveals novel gene-metabolite-disease links

Light intensity modulates the regulatory network of the shade avoidance response in Arabidopsis

Novel approach identifies SNPs in SLC2A10 and KCNK9 with evidence for parent-of-origin effect on body mass index

Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche

Plasma membrane H+-ATPase regulation is required for auxin gradient formation preceding phototropic growth