Personal information

Other IDs

Scopus Author ID: 55139195500

Activities

Collapse all

Employment (2)

Duke-NUS Graduate Medical School: Singapore, SG

2016-09-01 to present | Asst. Prof. (CVMD)
Employment
Source: Self-asserted source
Sebastian Schäfer

National Heart Centre Singapore: Singapore, SG

2014-12-01 to present | Senior Research Fellow (NHRIS)
Employment
Source: Self-asserted source
Sebastian Schäfer

Works (26)

Transcriptome-wide co-expression analysis identifies LRRC2 as a novel mediator of mitochondrial and cardiac function.

2017 | Journal article
PMID: 28158196
Contributors: McDermott-Roe C; Leleu M; Rowe GC; Palygin O; Bukowy JD; Kuo J; Rech M; Hermans-Beijnsberger S; Schaefer S; Adami E et al.
Source: Self-asserted source
Sebastian Schäfer via Europe PubMed Central

IL-11 is a crucial determinant of cardiovascular fibrosis.

Nature
2017-12 | Journal article
DOI: 10.1038/nature24676
PMID: 29160304
Source: Self-asserted source
Sebastian Schäfer via Europe PubMed Central

Natural genetic variation of the cardiac transcriptome in non-diseased donors and patients with dilated cardiomyopathy.

Genome biology
2017-09 | Journal article
DOI: 10.1186/s13059-017-1286-z
PMID: 28903782
PMC: PMC5598015
Source: Self-asserted source
Sebastian Schäfer via Europe PubMed Central

Titin-truncating variants affect heart function in disease cohorts and the general population.

2017-01 | Journal article
DOI: 10.1038/ng.3719
PMID: 27869827
Contributors: Schafer S; de Marvao A; Adami E; Fiedler LR; Ng B; Khin E; Rackham OJ; van Heesch S; Pua CJ; Kui M et al.
Source: Self-asserted source
Sebastian Schäfer via Europe PubMed Central
grade
Preferred source (of 2)‎

Development of a Comprehensive Sequencing Assay for Inherited Cardiac Condition Genes

Journal of Cardiovascular Translational Research
2016 | Journal article
DOI: 10.1007/s12265-016-9673-5
EID:

2-s2.0-84959167821
Contributors: Pua, C.J.; Bhalshankar, J.; Miao, K.; Walsh, R.; John, S.; Lim, S.Q.; Chow, K.; Buchan, R.; Soh, B.Y.; Lio, P.M. et al.
Source: Self-asserted source
Sebastian Schäfer via Scopus - Elsevier

A mutation in the glutamate-rich region of RNA-binding motif protein 20 causes dilated cardiomyopathy through missplicing of titin and impaired Frank-Starling mechanism.

2016-10 | Journal article
DOI: 10.1093/cvr/cvw192
PMID: 27496873
Contributors: Beqqali A; Bollen IA; Rasmussen TB; van den Hoogenhof MM; van Deutekom HW; Schafer S; Haas J; Meder B; Sørensen KE; van Oort RJ et al.
Source: Self-asserted source
Sebastian Schäfer via Europe PubMed Central
grade
Preferred source (of 2)‎

52 Genetic Loci Influencing Myocardial Mass.

2016-09 | Journal article
DOI: 10.1016/j.jacc.2016.07.729
PMID: 27659466
Contributors: van der Harst P; van Setten J; Verweij N; Vogler G; Franke L; Maurano MT; Wang X; Mateo Leach I; Eijgelsheim M; Sotoodehnia N et al.
Source: Self-asserted source
Sebastian Schäfer via Europe PubMed Central
grade
Preferred source (of 2)‎

Wars2 is a determinant of angiogenesis.

2016-07 | Journal article
DOI: 10.1038/ncomms12061
PMID: 27389904
PMC: PMC4941120
Contributors: Wang M; Sips P; Khin E; Rotival M; Sun X; Ahmed R; Widjaja AA; Schafer S; Yusoff P; Choksi PK et al.
Source: Self-asserted source
Sebastian Schäfer via Europe PubMed Central
grade
Preferred source (of 2)‎

Translational regulation shapes the molecular landscape of complex disease phenotypes.

2015 | Journal article
DOI: 10.1038/ncomms8200
PMID: 26007203
PMC: PMC4455061
Contributors: Schafer S; Adami E; Heinig M; Rodrigues KE; Kreuchwig F; Silhavy J; van Heesch S; Simaite D; Rajewsky N; Cuppen E et al.
Source: Self-asserted source
Sebastian Schäfer via Europe PubMed Central
grade
Preferred source (of 2)‎

Alternative Splicing Signatures in RNA-seq Data: Percent Spliced in (PSI).

2015-10 | Journal article
DOI: 10.1002/0471142905.hg1116s87
PMID: 26439713
Contributors: Schafer S; Miao K; Benson CC; Heinig M; Cook SA; Hubner N
Source: Self-asserted source
Sebastian Schäfer via Europe PubMed Central
grade
Preferred source (of 2)‎

The GYF domain protein CD2BP2 is critical for embryogenesis and podocyte function.

2015-10 | Journal article
DOI: 10.1093/jmcb/mjv039
PMID: 26082520
Contributors: Albert GI; Schell C; Kirschner KM; Schäfer S; Naumann R; Müller A; Kretz O; Kuropka B; Girbig M; Hübner N et al.
Source: Self-asserted source
Sebastian Schäfer via Europe PubMed Central
grade
Preferred source (of 2)‎

ZBTB17 (MIZ1) Is Important for the Cardiac Stress Response and a Novel Candidate Gene for Cardiomyopathy and Heart Failure.

2015-10 | Journal article
DOI: 10.1161/circgenetics.113.000690
PMID: 26175529
Contributors: Buyandelger B; Mansfield C; Kostin S; Choi O; Roberts AM; Ware JS; Mazzarotto F; Pesce F; Buchan R; Isaacson RL et al.
Source: Self-asserted source
Sebastian Schäfer via Europe PubMed Central
grade
Preferred source (of 2)‎

HEART DISEASE. Titin mutations in iPS cells define sarcomere insufficiency as a cause of dilated cardiomyopathy.

2015-08 | Journal article
DOI: 10.1126/science.aaa5458
PMID: 26315439
PMC: PMC4618316
Contributors: Hinson JT; Chopra A; Nafissi N; Polacheck WJ; Benson CC; Swist S; Gorham J; Yang L; Schafer S; Sheng CC et al.
Source: Self-asserted source
Sebastian Schäfer via Europe PubMed Central
grade
Preferred source (of 2)‎

Genomic landscape of rat strain and substrain variation.

2015-05 | Journal article
DOI: 10.1186/s12864-015-1594-1
PMID: 25943489
PMC: PMC4422378
Contributors: Hermsen R; de Ligt J; Spee W; Blokzijl F; Schäfer S; Adami E; Boymans S; Flink S; van Boxtel R; van der Weide RH et al.
Source: Self-asserted source
Sebastian Schäfer via Europe PubMed Central
grade
Preferred source (of 2)‎

histoneHMM: Differential analysis of histone modifications with broad genomic footprints.

2015-02 | Journal article
DOI: 10.1186/s12859-015-0491-6
PMID: 25884684
PMC: PMC4347972
Contributors: Heinig M; Colomé-Tatché M; Taudt A; Rintisch C; Schafer S; Pravenec M; Hubner N; Vingron M; Johannes F
Source: Self-asserted source
Sebastian Schäfer via Europe PubMed Central
grade
Preferred source (of 2)‎

Integrated allelic, transcriptional, and phenomic dissection of the cardiac effects of titin truncations in health and disease.

2015-01 | Journal article
DOI: 10.1126/scitranslmed.3010134
PMID: 25589632
PMC: PMC4560092
Contributors: Roberts AM; Ware JS; Herman DS; Schafer S; Baksi J; Bick AG; Buchan RJ; Walsh R; John S; Wilkinson S et al.
Source: Self-asserted source
Sebastian Schäfer via Europe PubMed Central
grade
Preferred source (of 2)‎

RNA-binding protein RBM20 represses splicing to orchestrate cardiac pre-mRNA processing

Journal of Clinical Investigation
2014 | Journal article
DOI: 10.1172/JCI74523
EID:

2-s2.0-84905460023
Contributors: Maatz, H.; Jens, M.; Liss, M.; Schafer, S.; Heinig, M.; Kirchner, M.; Adami, E.; Rintisch, C.; Dauksaite, V.; Radke, M.H. et al.
Source: Self-asserted source
Sebastian Schäfer via Scopus - Elsevier

Natural variation of histone modification and its impact on gene expression in the rat genome.

2014-06 | Journal article
DOI: 10.1101/gr.169029.113
PMID: 24793478
PMC: PMC4032858
Contributors: Rintisch C; Heinig M; Bauerfeind A; Schafer S; Mieth C; Patone G; Hummel O; Chen W; Cook S; Cuppen E et al.
Source: Self-asserted source
Sebastian Schäfer via Europe PubMed Central
grade
Preferred source (of 2)‎

Protease inhibitor 15, a candidate gene for abdominal aortic internal elastic lamina ruptures in the rat.

2014-06 | Journal article
DOI: 10.1152/physiolgenomics.00004.2014
PMID: 24790086
PMC: PMC4060037
Contributors: Falak S; Schafer S; Baud A; Hummel O; Schulz H; Gauguier D; Hubner N; Osborne-Pellegrin M
Source: Self-asserted source
Sebastian Schäfer via Europe PubMed Central
grade
Preferred source (of 2)‎

Recessive TTN truncating mutations define novel forms of core myopathy with heart disease.

2014-02 | Journal article
DOI: 10.1093/hmg/ddt494
PMID: 24105469
PMC: PMC3954110
Contributors: Chauveau C; Bonnemann CG; Julien C; Kho AL; Marks H; Talim B; Maury P; Arne-Bes MC; Uro-Coste E; Alexandrovich A et al.
Source: Self-asserted source
Sebastian Schäfer via Europe PubMed Central
grade
Preferred source (of 2)‎

Quantitative and qualitative proteome characteristics extracted from in-depth integrated genomics and proteomics analysis.

2013-12 | Journal article
DOI: 10.1016/j.celrep.2013.10.041
PMID: 24290761
Contributors: Low TY; van Heesch S; van den Toorn H; Giansanti P; Cristobal A; Toonen P; Schafer S; Hübner N; van Breukelen B; Mohammed S et al.
Source: Self-asserted source
Sebastian Schäfer via Europe PubMed Central
grade
Preferred source (of 2)‎

Fine mapping of the 1p36 deletion syndrome identifies mutation of PRDM16 as a cause of cardiomyopathy.

2013-07 | Journal article
DOI: 10.1016/j.ajhg.2013.05.015
PMID: 23768516
PMC: PMC3710750
Contributors: Arndt AK; Schafer S; Drenckhahn JD; Sabeh MK; Plovie ER; Caliebe A; Klopocki E; Musso G; Werdich AA; Kalwa H et al.
Source: Self-asserted source
Sebastian Schäfer via Europe PubMed Central
grade
Preferred source (of 2)‎

RBM20, a gene for hereditary cardiomyopathy, regulates titin splicing.

2012-05 | Journal article
DOI: 10.1038/nm.2693
PMID: 22466703
PMC: PMC3569865
Contributors: Guo W; Schafer S; Greaser ML; Radke MH; Liss M; Govindarajan T; Govindarajan T; Maatz H; Schulz H; Li S et al.
Source: Self-asserted source
Sebastian Schäfer via Europe PubMed Central
grade
Preferred source (of 2)‎

Engineered cell homing.

2011-12 | Journal article
DOI: 10.1182/blood-2010-10-311464
PMID: 22034631
PMC: PMC3242725
Contributors: Sarkar D; Spencer JA; Phillips JA; Zhao W; Schafer S; Spelke DP; Mortensen LJ; Ruiz JP; Vemula PK; Sridharan R et al.
Source: Self-asserted source
Sebastian Schäfer via Europe PubMed Central
grade
Preferred source (of 2)‎

Mimicking the inflammatory cell adhesion cascade by nucleic acid aptamer programmed cell-cell interactions.

2011-09 | Journal article
DOI: 10.1096/fj.10-178384
PMID: 21653192
PMC: PMC3157693
Contributors: Zhao W; Loh W; Droujinine IA; Teo W; Kumar N; Schafer S; Cui CH; Zhang L; Sarkar D; Karnik R et al.
Source: Self-asserted source
Sebastian Schäfer via Europe PubMed Central
grade
Preferred source (of 2)‎

Cell-surface sensors for real-time probing of cellular environments.

2011-07 | Journal article
DOI: 10.1038/nnano.2011.101
PMID: 21765401
PMC: PMC3163485
Contributors: Zhao W; Schafer S; Choi J; Yamanaka YJ; Lombardi ML; Bose S; Carlson AL; Phillips JA; Teo W; Droujinine IA et al.
Source: Self-asserted source
Sebastian Schäfer via Europe PubMed Central
grade
Preferred source (of 2)‎
How many people are using ORCID?