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Uppsala Universitet: Uppsala, SE

2004-02-01 to present | Professor (Department of Cell and Molecular Biology)
Employment
Source: Self-asserted source
Staffan Svärd

Education and qualifications (2)

Uppsala Universitet: Uppsala, SE

1990-07-01 to 1995-01-21 | PhD (Microbiology)
Education
Source: Self-asserted source
Staffan Svärd

Uppsala Universitet: Uppsala, SE

1985-09-01 to 1990-06-29 | Master of science, Molecular Biology (IBG)
Education
Source: Self-asserted source
Staffan Svärd

Works (50 of 109)

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Page 1 of 3

First report ofHexamita nelsoniin blue mussel (Mytilus edulis): morphology, phylogeny, and host-parasite interaction

2024-09-22 | Preprint
DOI: 10.1101/2024.09.18.613806
Contributors: Anders Alfjorden; Jon Jerlström Hultqvist; Staffan Svärd; Fabien Burki
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Crossref

Trophozoite fitness dictates the intestinal epithelial cell response to Giardia intestinalis infection

PLOS Pathogens
2023-05-04 | Journal article
DOI: 10.1371/journal.ppat.1011372
Contributors: Jana Grüttner; Alexander R. Paredez; Jorik M. van Rijn; Petra Geiser; Alexandra Florbrant; Dominic-Luc Webb; Per M. Hellström; Magnus Sundbom; Mikael E. Sellin; Staffan G. Svärd
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Crossref

Combined nanometric and phylogenetic analysis of unique endocytic compartments in Giardia lamblia sheds light on the evolution of endocytosis in Metamonada

BMC Biology
2022-09-21 | Journal article
DOI: 10.1186/s12915-022-01402-3
Contributors: Rui Santos; Ásgeir Ástvaldsson; Shweta V. Pipaliya; Jon Paulin Zumthor; Joel B. Dacks; Staffan Svärd; Adrian B. Hehl; Carmen Faso
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Crossref

Giardia duodenalis

Trends in Parasitology
2022-07 | Journal article
DOI: 10.1016/j.pt.2022.01.001
Contributors: Laura Rojas-López; Rafael C. Marques; Staffan G. Svärd
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Crossref

Combined nanometric and phylogenetic analysis of unique endocytic compartments in Giardia lamblia sheds light on the evolution of endocytosis in Fornicata

2022-04-14 | Preprint
DOI: 10.1101/2022.04.14.488357
Contributors: Rui Santos; Ásgeir Ástvaldsson; Shweta V. Pipaliya; Jon Paulin Zumthor; Joel B. Dacks; Staffan Svärd; Adrian B. Hehl; Carmen Faso
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Crossref

High-Definition DIC Imaging Uncovers Transient Stages of Pathogen Infection Cycles on the Surface of Human Adult Stem Cell-Derived Intestinal Epithelium

mBio
2022-02-22 | Journal article
DOI: 10.1128/mbio.00022-22
Contributors: Jorik M. van Rijn; Jens Eriksson; Jana Grüttner; Magnus Sundbom; Dominic-Luc Webb; Per M. Hellström; Staffan G. Svärd; Mikael E. Sellin; Russell Vance
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Crossref

A Detailed Gene Expression Map of Giardia Encystation

Genes
2021-11-30 | Journal article
DOI: 10.3390/genes12121932
Contributors: Laura Rojas-López; Sascha Krakovka; Elin Einarsson; Ulf Ribacke; Feifei Xu; Jon Jerlström-Hultqvist; Staffan G. Svärd
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High definition DIC imaging uncovers transient stages of pathogen infection cycles on the surface of human adult stem cell-derived intestinal epithelium

2021-08-24 | Other
DOI: 10.1101/2021.08.24.457471
Contributors: Jorik M. van Rijn; Jens Eriksson; Jana Grüttner; Magnus Sundbom; Dominic-Luc Webb; Per M. Hellström; Staffan G. Svärd; Mikael E. Sellin
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Crossref

The compact genome of Giardia muris reveals important steps in the evolution of intestinal protozoan parasites

Microbial Genomics
2020-08-01 | Journal article
DOI: 10.1099/mgen.0.000402
Contributors: Feifei Xu; Alejandro Jiménez-González; Elin Einarsson; Ásgeir Ástvaldsson; Dimitra Peirasmaki; Lars Eckmann; Jan O. Andersson; Staffan G. Svärd; Jon Jerlström-Hultqvist
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Crossref

A novel high-resolution multilocus sequence typing of Giardia intestinalis Assemblage A isolates reveals zoonotic transmission, clonal outbreaks and recombination

Infection, Genetics and Evolution
2018-06 | Journal article
DOI: 10.1016/j.meegid.2018.02.012
Contributors: Johan Ankarklev; Marianne Lebbad; Elin Einarsson; Oscar Franzén; Harri Ahola; Karin Troell; Staffan G. Svärd
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Crossref

Synchronization of Pathogenic Protozoans.

Methods in molecular biology (Clifton, N.J.)
2017 | Journal article
DOI: 10.1007/978-1-4939-6603-5_15
PMID: 27815907
Contributors: Svärd S; Troell K
Source: Self-asserted source
Staffan Svärd via Europe PubMed Central

Transcriptomics Indicates Active and Passive Metronidazole Resistance Mechanisms in Three Seminal Giardia Lines.

Frontiers in microbiology
2017 | Journal article
DOI: 10.3389/fmicb.2017.00398
PMID: 28367140
PMC: PMC5355454
Contributors: Ansell BR; Baker L; Emery SJ; McConville MJ; Svärd SG; Gasser RB; Jex AR
Source: Self-asserted source
Staffan Svärd via Europe PubMed Central

Host specificity in the Giardia duodenalis species complex.

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases
2017-12 | Journal article
DOI: 10.1016/j.meegid.2017.12.001
PMID: 29225147
Contributors: Cacciò SM; Lalle M; Svärd SG
Source: Self-asserted source
Staffan Svärd via Europe PubMed Central

Characterization of the Giardia intestinalis secretome during interaction with human intestinal epithelial cells: The impact on host cells

PLOS Neglected Tropical Diseases
2017-12-11 | Journal article
DOI: 10.1371/journal.pntd.0006120
Contributors: Showgy Y. Ma’ayeh; Armando Jardim; Jingyi Liu; Dimitra Peirasmaki; Katarina Hörnaeus; Sara Bergström Lind; Manfred Grabherr; Jonas Bergquist; Staffan G. Svärd
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Crossref

Endoplasmic reticulum is the sorting core facility in the Golgi-lacking protozoan Giardia lamblia.

Traffic (Copenhagen, Denmark)
2017-09 | Journal article
DOI: 10.1111/tra.12501
PMID: 28696565
Contributors: Zamponi N; Zamponi E; Mayol GF; Lanfredi-Rangel A; Svärd SG; Touz MC
Source: Self-asserted source
Staffan Svärd via Europe PubMed Central

Recent advances in the genomic and molecular biology of Giardia.

Acta tropica
2017-09 | Journal article
DOI: 10.1016/j.actatropica.2017.09.004
PMID: 28888474
Contributors: Ortega-Pierres MG; Jex AR; Ansell BRE; Svärd SG
Source: Self-asserted source
Staffan Svärd via Europe PubMed Central

Giardia intestinalis mitosomes undergo synchronized fission but not fusion and are constitutively associated with the endoplasmic reticulum.

BMC biology
2017-04 | Journal article
DOI: 10.1186/s12915-017-0361-y
PMID: 28372543
PMC: PMC5377515
Contributors: Voleman L; Najdrová V; Ástvaldsson Á; Tůmová P; Einarsson E; Švindrych Z; Hagen GM; Tachezy J; Svärd SG; Doležal P
Source: Self-asserted source
Staffan Svärd via Europe PubMed Central

Giardia-specific cellular immune responses in post-giardiasis chronic fatigue syndrome.

BMC immunology
2017-01 | Journal article
DOI: 10.1186/s12865-017-0190-3
PMID: 28129747
PMC: PMC5279576
Contributors: Hanevik K; Kristoffersen E; Mørch K; Rye KP; Sørnes S; Svärd S; Bruserud Ø; Langeland N
Source: Self-asserted source
Staffan Svärd via Europe PubMed Central

Comparative Cell Biology and Evolution of Annexins in Diplomonads.

mSphere
2016 | Journal article
DOI: 10.1128/msphere.00032-15
PMID: 27303715
PMC: PMC4863580
Contributors: Einarsson E; Ástvaldsson Á; Hultenby K; Andersson JO; Svärd SG; Jerlström-Hultqvist J
Source: Self-asserted source
Staffan Svärd via Europe PubMed Central

Erratum to: On the reversibility of parasitism: adaptation to a free-living lifestyle via gene acquisitions in the diplomonad Trepomonas sp. PC1.

BMC biology
2016 | Journal article
DOI: 10.1186/s12915-016-0302-1
PMID: 27619515
PMC: PMC5018941
Contributors: Xu F; Jerlström-Hultqvist J; Kolisko M; Simpson AG; Roger AJ; Svärd SG; Andersson JO
Source: Self-asserted source
Staffan Svärd via Europe PubMed Central

An up-date on Giardia and giardiasis.

Current opinion in microbiology
2016-12 | Journal article
DOI: 10.1016/j.mib.2016.07.019
PMID: 27501461
Contributors: Einarsson E; Ma'ayeh S; Svärd SG
Source: Self-asserted source
Staffan Svärd via Europe PubMed Central

Specific histone modifications play critical roles in the control of encystation and antigenic variation in the early-branching eukaryote Giardia lamblia.

The international journal of biochemistry & cell biology
2016-12 | Journal article
DOI: 10.1016/j.biocel.2016.10.010
PMID: 27771437
Contributors: Carranza PG; Gargantini PR; Prucca CG; Torri A; Saura A; Svärd S; Lujan HD
Source: Self-asserted source
Staffan Svärd via Europe PubMed Central

Divergent Transcriptional Responses to Physiological and Xenobiotic Stress in Giardia duodenalis.

Antimicrobial agents and chemotherapy
2016-10 | Journal article
DOI: 10.1128/aac.00977-16
PMID: 27458219
PMC: PMC5038253
Contributors: Ansell BR; McConville MJ; Baker L; Korhonen PK; Emery SJ; Svärd SG; Gasser RB; Jex AR
Source: Self-asserted source
Staffan Svärd via Europe PubMed Central

On the reversibility of parasitism: adaptation to a free-living lifestyle via gene acquisitions in the diplomonad Trepomonas sp. PC1.

BMC biology
2016-08 | Journal article
DOI: 10.1186/s12915-016-0284-z
PMID: 27480115
PMC: PMC4967989
Contributors: Xu F; Jerlström-Hultqvist J; Kolisko M; Simpson AG; Roger AJ; Svärd SG; Andersson JO
Source: Self-asserted source
Staffan Svärd via Europe PubMed Central

Coordinated Changes in Gene Expression Throughout Encystation of Giardia intestinalis.

PLoS neglected tropical diseases
2016-03 | Journal article
DOI: 10.1371/journal.pntd.0004571
PMID: 27015092
PMC: PMC4807828
Contributors: Einarsson E; Troell K; Hoeppner MP; Grabherr M; Ribacke U; Svärd SG
Source: Self-asserted source
Staffan Svärd via Europe PubMed Central

Human Memory CD4+ T Cell Immune Responses against Giardia lamblia.

Clinical and vaccine immunology : CVI
2016-01 | Journal article
DOI: 10.1128/cvi.00419-15
PMID: 26376930
PMC: PMC4711086
Contributors: Saghaug CS; Sørnes S; Peirasmaki D; Svärd S; Langeland N; Hanevik K
Source: Self-asserted source
Staffan Svärd via Europe PubMed Central

Comparative genomic analyses of freshly isolated Giardia intestinalis assemblage A isolates.

BMC genomics
2015 | Journal article
DOI: 10.1186/s12864-015-1893-6
PMID: 26370391
PMC: PMC4570179
Contributors: Ankarklev J; Franzén O; Peirasmaki D; Jerlström-Hultqvist J; Lebbad M; Andersson J; Andersson B; Svärd SG
Source: Self-asserted source
Staffan Svärd via Europe PubMed Central

Time-Dependent Transcriptional Changes in Axenic Giardia duodenalis Trophozoites.

PLoS neglected tropical diseases
2015-12 | Journal article
DOI: 10.1371/journal.pntd.0004261
PMID: 26636323
PMC: PMC4670223
Contributors: Ansell BR; McConville MJ; Baker L; Korhonen PK; Young ND; Hall RS; Rojas CA; Svärd SG; Gasser RB; Jex AR
Source: Self-asserted source
Staffan Svärd via Europe PubMed Central

Transcriptional profiling of Giardia intestinalis in response to oxidative stress.

International journal for parasitology
2015-12 | Journal article
DOI: 10.1016/j.ijpara.2015.07.005
PMID: 26341007
Contributors: Ma'ayeh SY; Knörr L; Svärd SG
Source: Self-asserted source
Staffan Svärd via Europe PubMed Central

Drug resistance in Giardia duodenalis.

Biotechnology advances
2015-11 | Journal article
DOI: 10.1016/j.biotechadv.2015.04.009
PMID: 25922317
Contributors: Ansell BR; McConville MJ; Ma'ayeh SY; Dagley MJ; Gasser RB; Svärd SG; Jex AR
Source: Self-asserted source
Staffan Svärd via Europe PubMed Central

UV irradiation responses in Giardia intestinalis.

Experimental parasitology
2015-07 | Journal article
DOI: 10.1016/j.exppara.2015.03.024
PMID: 25825252
Contributors: Einarsson E; Svärd SG; Troell K
Source: Self-asserted source
Staffan Svärd via Europe PubMed Central

A real-time assemblage-specific PCR assay for the detection of Giardia duodenalis assemblages A, B and E in fecal samples.

Veterinary parasitology
2015-06 | Journal article
DOI: 10.1016/j.vetpar.2015.04.017
PMID: 25935292
Contributors: Van Lith L; Šoba B; Vizcaino VV; Svard S; Sprong H; Tosini F; Pozio E; Cacciò SM
Source: Self-asserted source
Staffan Svärd via Europe PubMed Central

Gene expression changes during Giardia-host cell interactions in serum-free medium.

Molecular and biochemical parasitology
2014-10 | Journal article
DOI: 10.1016/j.molbiopara.2014.09.007
PMID: 25286381
Contributors: Ferella M; Davids BJ; Cipriano MJ; Birkeland SR; Palm D; Gillin FD; McArthur AG; Svärd S
Source: Self-asserted source
Staffan Svärd via Europe PubMed Central

Rolf Bernander (1956-2014): pioneer of the archaeal cell cycle.

Molecular microbiology
2014-06 | Journal article
DOI: 10.1111/mmi.12608
PMID: 24865634
Contributors: Ettema TJ; Lindås AC; Hjort K; Poplawski AB; Kaessmann H; Grogan DW; Kelman Z; Andersson AF; Pelve EA; Lundgren M et al.
Source: Self-asserted source
Staffan Svärd via Europe PubMed Central

The genome of Spironucleus salmonicida highlights a fish pathogen adapted to fluctuating environments.

PLoS genetics
2014-02 | Journal article
DOI: 10.1371/journal.pgen.1004053
PMID: 24516394
PMC: PMC3916229
Contributors: Xu F; Jerlström-Hultqvist J; Einarsson E; Astvaldsson A; Svärd SG; Andersson JO
Source: Self-asserted source
Staffan Svärd via Europe PubMed Central

Hydrogenosomes in the diplomonad Spironucleus salmonicida.

Nature communications
2013 | Journal article
DOI: 10.1038/ncomms3493
PMID: 24042146
PMC: PMC3778541
Contributors: Jerlström-Hultqvist J; Einarsson E; Xu F; Hjort K; Ek B; Steinhauf D; Hultenby K; Bergquist J; Andersson JO; Svärd SG
Source: Self-asserted source
Staffan Svärd via Europe PubMed Central

The role of arginine and arginine-metabolizing enzymes during Giardia - host cell interactions in vitro.

BMC microbiology
2013 | Journal article
DOI: 10.1186/1471-2180-13-256
PMID: 24228819
PMC: PMC4225669
Contributors: Stadelmann B; Hanevik K; Andersson MK; Bruserud O; Svärd SG
Source: Self-asserted source
Staffan Svärd via Europe PubMed Central

Transcriptome profiling of Giardia intestinalis using strand-specific RNA-seq.

PLoS computational biology
2013 | Journal article
DOI: 10.1371/journal.pcbi.1003000
PMID: 23555231
PMC: PMC3610916
Contributors: Franzén O; Jerlström-Hultqvist J; Einarsson E; Ankarklev J; Ferella M; Andersson B; Svärd SG
Source: Self-asserted source
Staffan Svärd via Europe PubMed Central

Allelic sequence heterozygosity in single Giardia parasites.

BMC microbiology
2012 | Journal article
DOI: 10.1186/1471-2180-12-65
PMID: 22554281
PMC: PMC3438080
Contributors: Ankarklev J; Svärd SG; Lebbad M
Source: Self-asserted source
Staffan Svärd via Europe PubMed Central

Arginine consumption by the intestinal parasite Giardia intestinalis reduces proliferation of intestinal epithelial cells.

PloS one
2012 | Journal article
DOI: 10.1371/journal.pone.0045325
PMID: 23028934
PMC: PMC3446895
Contributors: Stadelmann B; Merino MC; Persson L; Svärd SG
Source: Self-asserted source
Staffan Svärd via Europe PubMed Central

Common coinfections of Giardia intestinalis and Helicobacter pylori in non-symptomatic Ugandan children.

PLoS neglected tropical diseases
2012 | Journal article
DOI: 10.1371/journal.pntd.0001780
PMID: 22953010
PMC: PMC3429385
Contributors: Ankarklev J; Hestvik E; Lebbad M; Lindh J; Kaddu-Mulindwa DH; Andersson JO; Tylleskär T; Tumwine JK; Svärd SG
Source: Self-asserted source
Staffan Svärd via Europe PubMed Central

Detection of Giardia duodenalis assemblages A and B in human feces by simple, assemblage-specific PCR assays.

PLoS neglected tropical diseases
2012 | Journal article
DOI: 10.1371/journal.pntd.0001776
PMID: 22953009
PMC: PMC3429382
Contributors: Vanni I; Cacciò SM; van Lith L; Lebbad M; Svärd SG; Pozio E; Tosini F
Source: Self-asserted source
Staffan Svärd via Europe PubMed Central

Stable transfection of the diplomonad parasite Spironucleus salmonicida.

Eukaryotic cell
2012-11 | Journal article
DOI: 10.1128/ec.00179-12
PMID: 22983987
PMC: PMC3486028
Contributors: Jerlström-Hultqvist J; Einarsson E; Svärd SG
Source: Self-asserted source
Staffan Svärd via Europe PubMed Central

Alpha-1 giardin is an annexin with highly unusual calcium-regulated mechanisms.

Journal of molecular biology
2012-10 | Journal article
DOI: 10.1016/j.jmb.2012.06.041
PMID: 22796298
Contributors: Weeratunga SK; Osman A; Hu NJ; Wang CK; Mason L; Svärd S; Hope G; Jones MK; Hofmann A
Source: Self-asserted source
Staffan Svärd via Europe PubMed Central

Plasmid vectors for proteomic analyses in Giardia: purification of virulence factors and analysis of the proteasome.

Eukaryotic cell
2012-07 | Journal article
DOI: 10.1128/ec.00092-12
PMID: 22611020
PMC: PMC3416501
Contributors: Jerlström-Hultqvist J; Stadelmann B; Birkestedt S; Hellman U; Svärd SG
Source: Self-asserted source
Staffan Svärd via Europe PubMed Central

Laboratory cryo soft X-ray microscopy.

Journal of structural biology
2012-02 | Journal article
DOI: 10.1016/j.jsb.2011.11.015
PMID: 22119891
Contributors: Hertz HM; von Hofsten O; Bertilson M; Vogt U; Holmberg A; Reinspach J; Martz D; Selin M; Christakou AE; Jerlström-Hultqvist J et al.
Source: Self-asserted source
Staffan Svärd via Europe PubMed Central

Synchronization of pathogenic protozoans.

Methods in molecular biology (Clifton, N.J.)
2011 | Journal article
DOI: 10.1007/978-1-61779-182-6_13
PMID: 21755450
Contributors: Svärd S; Troell K
Source: Self-asserted source
Staffan Svärd via Europe PubMed Central

Human cellular immune response against Giardia lamblia 5 years after acute giardiasis.

The Journal of infectious diseases
2011-12 | Journal article
DOI: 10.1093/infdis/jir639
PMID: 21990423
Contributors: Hanevik K; Kristoffersen E; Svard S; Bruserud O; Ringqvist E; Sørnes S; Langeland N
Source: Self-asserted source
Staffan Svärd via Europe PubMed Central

Α1-giardin based live heterologous vaccine protects against Giardia lamblia infection in a murine model.

Vaccine
2011-11 | Journal article
DOI: 10.1016/j.vaccine.2011.09.126
PMID: 22001876
PMC: PMC4045459
Contributors: Jenikova G; Hruz P; Andersson MK; Tejman-Yarden N; Ferreira PC; Andersen YS; Davids BJ; Gillin FD; Svärd SG; Curtiss R et al.
Source: Self-asserted source
Staffan Svärd via Europe PubMed Central

Multilocus genotyping of human Giardia isolates suggests limited zoonotic transmission and association between assemblage B and flatulence in children.

PLoS neglected tropical diseases
2011-08 | Journal article
DOI: 10.1371/journal.pntd.0001262
PMID: 21829745
PMC: PMC3149019
Contributors: Lebbad M; Petersson I; Karlsson L; Botero-Kleiven S; Andersson JO; Svenungsson B; Svärd SG
Source: Self-asserted source
Staffan Svärd via Europe PubMed Central
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