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Greece, Spain, Belgium

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Employment (7)

Université libre de Bruxelles (ULB): 1050, Brussels, BE

Employment
Source: check_circle
Université libre de Bruxelles

Université Libre de Bruxelles: Brussels, BE

2024-12 to present | Junior Group leader
Employment
Source: Self-asserted source
Panagiotis Karras

VIB-KU Leuven Center for Cancer Biology: Leuven, BE

2017-10-01 to 2024-11 | Postdoctoral researcher
Employment
Source: Self-asserted source
Panagiotis Karras

Centro Nacional de Investigaciones Oncológicas: Madrid, Madrid, ES

2011-10-10 to 2017-08-31 | PhD fellow (Molecular Oncology)
Employment
Source: Self-asserted source
Panagiotis Karras

University of Ioannina School of Medicine: Ioannina, GR

2009-09-01 to 2011-09-09 | MSc student (Biology)
Employment
Source: Self-asserted source
Panagiotis Karras

University of Ioannina School of Sciences and Technology: Ioannina, GR

2007-09-03 to 2008-08-29 | Undergraduate thesis (Biological Applications and Technologies)
Employment
Source: Self-asserted source
Panagiotis Karras

Geniko Panarkadiko Nosokomeio Tripoles: Tripoli, GR

2007-07-02 to 2007-08-31 | Laboratory Assistant (Biochemistry )
Employment
Source: Self-asserted source
Panagiotis Karras

Education and qualifications (3)

Universidad Autónoma de Madrid: Madrid, Madrid, ES

2011-10-10 to 2017-07-07 | PhD (Faculty of Medicine)
Education
Source: Self-asserted source
Panagiotis Karras

University of Ioannina School of Medicine: Ioannina, GR

2008-09-01 to 2011-09-01 | MSc in biotechnology
Education
Source: Self-asserted source
Panagiotis Karras

University of Ioannina School of Sciences and Technology: Ioannina, GR

2003-09-01 to 2008-07-11 | Diploma (Biological Applications and Technologies)
Education
Source: Self-asserted source
Panagiotis Karras

Funding (5)

Spatio-temporal functional characterization of melanoma stem cells

2021-10 to present | Salary award
Belgian Foundation against Cancer (Leuven, BE)
Source: Self-asserted source
Panagiotis Karras

Non-genetic plasticity as driver of melanoma intra-tumor heterogeneity and metastatic dissemination

2019-11 to 2022-11 | Grant
Fonds Wetenschappelijk Onderzoek (Brussels, BE)
Source: Self-asserted source
Panagiotis Karras

InHUMAN

2019-04 to 2021-04 | Contract
European Commission (Brussels, BE)
Source: Self-asserted source
Panagiotis Karras

Novel roles of melanoma scavengers in progression and metastatic dissemination

2011-10 to 2015-10 | Grant
“la Caixa” Foundation (Madrid, Madrid, ES)
Source: Self-asserted source
Panagiotis Karras

Undegraduate studies

2005-01 to 2008-07 | Salary award
Bakalas foundation (Arcadia, GR)
Source: Self-asserted source
Panagiotis Karras

Works (35)

Decoding the interplay between genetic and non-genetic drivers of metastasis.

Nature
2024-05 | Journal article
DOI: 10.1038/s41586-024-07302-6
SOURCE-WORK-ID:

4159144

PMID: 38750233
Part of ISSN: 0028-0836
Contributors: Panagiotis Karras; James R M Black; Nicholas McGranahan; Jean-Christophe Marine
Source: check_circle
KU Leuven

SECRETED APOE REWIRES MELANOMA CELL STATE VULNERABILITY TO FERROPTOSIS

Science Advances
2024-02-13 | Dissertation or Thesis
DOI: 10.1126/sciadv.adp6164
SOURCE-WORK-ID:

4140752

PMID: 39413195
Part of ISSN: 2375-2548
Contributors: Sanket Mohan More; Patrizia Agostinis
Source: check_circle
KU Leuven

A TCF4-dependent gene regulatory network confers resistance to immunotherapy in melanoma

Cell
2024-01-04 | Journal article
DOI: 10.1016/j.cell.2023.11.037
SOURCE-WORK-ID:

4133803

PMID: 38181739
Part of ISSN: 0092-8674
WOSUID:

WOS:001153173400001
Contributors: Joanna Pozniak; Dennis Pedri; Ewout Landeloos; Yannick Van Herck; Asier Antoranz; Lukas Vanwynsberghe; Ada Nowosad; Niccolo Roda; Samira Makhzami; Greet Bervoets et al.
Source: check_circle
KU Leuven

Perivascular niches: critical hubs in cancer evolution

Trends In Cancer
2023-11 | Journal article
DOI: 10.1016/j.trecan.2023.06.010
SOURCE-WORK-ID:

4093810

PMID: 37453870
Part of ISSN: 2405-8025
WOSUID:

WOS:001114809400001
Contributors: Ada Nowosad; Jean-Christophe Marine; Panagiotis Karras
Source: check_circle
KU Leuven

Aspartate signaling increases the aggressiveness of lung metastases by inducing eIF5A mediated translation

2023-08-02 | Lecture
SOURCE-WORK-ID:

4137068
Contributors: Ginevra Doglioni; Patricia Altea-Manzano; Sebastian Igelmann; Juan Fernandez-Garcia; Arnaud Blomme; Yawen Liu; Max Nobis; Tine Tricot; Sarah El Kharraz; Ning An et al.
Source: check_circle
KU Leuven

Perivascular niches dictate developmental cellular hierarchies during melanoma growth

Journal Of Investigative Dermatology
2022-12 | Lecture
SOURCE-WORK-ID:

4070554

Part of ISSN: 0022-202X
WOSUID:

WOS:000897174500417
Contributors: Panagiotis Karras; I Bordeu; J Pozniak; Ada Nowosad; Cecilia Pazzi; Nina Van Raemdonck; Ewout Landeloos; C Blanpain; F Rambow; J Marine
Source: check_circle
KU Leuven

Comparative single-cell RNA-sequencing profiling of BMP4-treated primary glioma cultures reveals therapeutic markers

Neuro-Oncology
2022-12-01 | Journal article
DOI: 10.1093/neuonc/noac143
SOURCE-WORK-ID:

3756300

PMC: PMC9713526
PMID: 35639831
Part of ISSN: 1522-8517
WOSUID:

WOS:000811788300001
Contributors: Iris S C Verploegh; Andrea Conidi; Rutger W W Brouwer; Hayri E Balcioglu; Panagiotis Karras; Samira Makhzami; Anne Korporaal; Jean-Christophe Marine; Martine Lamfers; Wilfred F J van IJcken et al.
Source: check_circle
KU Leuven

A cellular hierarchy in melanoma uncouples growth and metastasis (vol 610, pg 190, 2022)

Nature
2022-11-03 | Other
DOI: 10.1038/s41586-022-05415-4
SOURCE-WORK-ID:

3909962

PMID: 36261534
Part of ISSN: 0028-0836
WOSUID:

WOS:000870207100007
Contributors: Panagiotis Karras; Ignacio Bordeu; Joanna Pozniak; Ada Nowosad; Cecilia Pazzi; Nina Van Raemdonck; Ewout Landeloos; Yannick Van Herck; Dennis Pedri; Greet Bervoets et al.
Source: check_circle
KU Leuven

A cellular hierarchy in melanoma uncouples growth and metastasis

Nature
2022-10-06 | Journal article
DOI: 10.1038/s41586-022-05242-7
SOURCE-WORK-ID:

3838446

PMC: PMC10439739
PMID: 36131018
Part of ISSN: 0028-0836
WOSUID:

WOS:000858380500001
Contributors: Panagiotis Karras; Ignacio Bordeu; Joanna Pozniak; Ada Nowosad; Cecilia Pazzi; Nina Van Raemdonck; Ewout Landeloos; Yannick Van Herck; Dennis Pedri; Greet Bervoets et al.
Source: check_circle
KU Leuven

PHGDH heterogeneity potentiates cancer cell dissemination and metastasis (vol 605. pg 747, 2022)

Nature
2022-09-15 | Other
DOI: 10.1038/s41586-022-05226-7
SOURCE-WORK-ID:

3801448

PMC: PMC9904429
PMID: 36042336
Part of ISSN: 0028-0836
WOSUID:

WOS:000847618400002
Contributors: Matteo Rossi; Patricia Altea-Manzano; Margherita Demicco; Ginevra Doglioni; Laura Bornes; Marina Fukano; Anke Vandekeere; Juan Fernandez-Garcia; Carla Riera-Domingo et al.
Source: check_circle
KU Leuven

A TCF4/BRD4-dependent regulatory network confers cross-resistance to targeted and immune checkpoint therapy in melanoma

2022-08-13 | Preprint
DOI: 10.1101/2022.08.11.502598
Contributors: Joanna Pozniak; Dennis Pedri; Ewout Landeloos; Yannick Van Herck; Asier Antoranz; Panagiotis Karras; Ada Nowosad; Samira Makhzami; Greet Bervoets; Michael Dewaele et al.
Source: check_circle
Crossref
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A stromal Integrated Stress Response activates perivascular cancer-associated fibroblasts to drive angiogenesis and tumour progression

Nature Cell Biology
2022-06 | Journal article
DOI: 10.1038/s41556-022-00918-8
SOURCE-WORK-ID:

3756458

PMC: PMC9203279
PMID: 35654839
Part of ISSN: 1465-7392
WOSUID:

WOS:000805081300001
Contributors: Ioannis I Verginadis; Harris Avgousti; James Monslow; Giorgos Skoufos; Frank Chinga; Kyle Kim; Nektaria Maria Leli; Ilias V Karagounis; Brett I Bell; Anastasia Velalopoulou et al.
Source: check_circle
KU Leuven

Finding Geo-Social Cohorts in Location-Based Social Networks

Lecture Notes in Artificial Intelligence
2021 | Conference paper
DOI: 10.1007/978-3-030-85899-5_27
SOURCE-WORK-ID:

4032421

Part of ISSN: 0302-9743
WOSUID:

WOS:000781765500027
Contributors: Muhammad Aamir Saleem; Toon Calders; Torben Bach Pedersen; Panagiotis Karras; U L Hou; M Spaniol; Y Sakurai; J Chen
Source: check_circle
KU Leuven

Cancer stem cells: advances in biology and clinical translation-a Keystone Symposia report

Annals Of The New York Academy Of Sciences
2021-12 | Journal article
DOI: 10.1111/nyas.14719
SOURCE-WORK-ID:

3647384

PMC: PMC9153245
PMID: 34850398
Part of ISSN: 0077-8923
WOSUID:

WOS:000723830500001
Contributors: Jennifer Cable; Duanqing Pei; Lola M Reid; Xin Wei Wang; Sonam Bhatia; Panagiotis Karras; Jan Joseph Melenhorst; Markus Grompe; Justin D Lathia; Erwei Song et al.
Source: check_circle
KU Leuven

A developmental cellular hierarchy in melanoma uncouples growth and metastatic phenotypes

Journal Of Investigative Dermatology
2021-10 | Lecture
SOURCE-WORK-ID:

3621432

Part of ISSN: 0022-202X
WOSUID:

WOS:000706854500248
Contributors: Panagiotis Karras; I Bordeu; J Pozniak; Cecilia Pazzi; Dennis Pedri; Ewout Landeloos; Nina Van Raemdonck; Yannick Van Herck; Francesca Maria Bosisio; Oliver Bechter et al.
Source: check_circle
KU Leuven

Activation of the integrated stress response confers vulnerability to mitoribosome-targeting antibiotics in melanoma

Journal of Experimental Medicine
2021-09-06 | Journal article
DOI: 10.1084/jem.20210571
Contributors: Roberto Vendramin; Vicky Katopodi; Sonia Cinque; Angelina Konnova; Zorica Knezevic; Sara Adnane; Yvessa Verheyden; Panagiotis Karras; Ewout Demesmaeker; Francesca M. Bosisio et al.
Source: check_circle
Crossref
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Evolutionary predictability of genetic versus nongenetic resistance to anticancer drugs in melanoma

Cancer Cell
2021-08-09 | Journal article
DOI: 10.1016/j.ccell.2021.05.015
SOURCE-WORK-ID:

3473590

PMID: 34143978
Part of ISSN: 1535-6108
WOSUID:

WOS:000684448300021
Contributors: Oskar Marin-Bejar; Aljosja Rogiers; Michael Dewaele; Julia Femel; Panagiotis Karras; Joanna Pozniak; Greet Bervoets; Nina Van Raemdonck; Dennis Pedri; Toon Swings et al.
Source: check_circle
KU Leuven

Epithelial-to-mesenchymal-like transition events in melanoma.

The FEBS journal
2021-05 | Journal article
DOI: 10.1111/febs.16021
PMID: 33999497
Contributors: Pedri D; Karras P; Landeloos E; Marine JC; Rambow F
Source: Self-asserted source
Panagiotis Karras via Europe PubMed Central
grade
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The primary tumor secretome alters the metabolism of the pre-metastatic niche and promotes metastasis

2021-04-22 | Lecture
SOURCE-WORK-ID:

4137063
Contributors: Ginevra Doglioni; Juan Fernandez-Garcia; Carla Riera-Domingo; Patricia Altea-Manzano; Gianmarco Rinaldi; H Furkan Alkan; Panagiotis Karras; Joke Van Elsen; Ines Vermeire; Dorien Broekaert et al.
Source: check_circle
KU Leuven

Cross-species analysis of enhancer logic using deep learning

Genome Research
2020-12 | Journal article
DOI: 10.1101/gr.260844.120
SOURCE-WORK-ID:

3097215

PMC: PMC7706731
PMID: 32732264
Part of ISSN: 1088-9051
WOSUID:

WOS:000596027700003
Contributors: Liesbeth Minnoye; Ibrahim Ihsan Taskiran; David Mauduit; Maurizio Fazio; Linde van Aerschot; Gert Hulselmans; Valerie Christiaens; Samira Makhzami; Monika Seltenhammer; Panagiotis Karras et al.
Source: check_circle
KU Leuven

A neural crest stem cell-like state drives nongenetic resistance to targeted therapy in melanoma

bioRxiv
2020-12-16 | Other
DOI: 10.1101/2020.12.15.422929
SOURCE-WORK-ID:

3353622
Contributors: Oskar Marin-Bejar; Aljosja Rogiers; Michael Dewaele; Julia Femel; Panagiotis Karras; Joanna Pozniak; Greet Bervoets; Nina Van Raemdonck; Dennis Pedri; Toon Swings et al.
Source: check_circle
KU Leuven

Disseminated Melanoma Cells Transdifferentiate into Endothelial Cells in Intravascular Niches at Metastatic Sites

Cell Reports
2020-06 | Journal article
DOI: 10.1016/j.celrep.2020.107765
Part of ISSN: 2211-1247
Source: Self-asserted source
Panagiotis Karras
grade
Preferred source (of 2)‎

Activation of the Integrated Stress Response in drug-tolerant melanoma cells confers vulnerability to mitoribosome-targeting antibiotics

2020-06-26 | Preprint
DOI: 10.1101/2020.06.26.173492
Contributors: Roberto Vendramin; Angelina Konnova; Sara Adnane; Sonia Cinque; Vicky Katopodi; Zorica Knezevic; Panangiotis Karras; Ewout Demesmaeker; Francesca M Bosisio; Lara Rizzotto et al.
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Cross-species analysis of melanoma enhancer logic using deep learning

bioRxiv
2019 | Other
DOI: 10.1101/2019.12.21.885715
SOURCE-WORK-ID:

2916177
Contributors: Liesbeth Minnoye; Ibrahim Ihsan Taskiran; David Mauduit; Maurizio Fazio; Linde Van Aerschot; Gert Hulsemans; Valerie Christiaens; Samira Makhzami; Monika Seltenhammer; Panagiotis Karras et al.
Source: check_circle
KU Leuven

Peritumoral activation of the Hippo pathway effectors YAP and TAZ suppresses liver cancer in mice.

Science (New York, N.Y.)
2019-11 | Journal article
DOI: 10.1126/science.aaw9886
PMID: 31754005
Contributors: Moya IM; Castaldo SA; Van den Mooter L; Soheily S; Sansores-Garcia L; Jacobs J; Mannaerts I; Xie J; Verboven E; Hillen H et al.
Source: Self-asserted source
Panagiotis Karras via Europe PubMed Central
grade
Preferred source (of 2)‎

p62/SQSTM1 Fuels Melanoma Progression by Opposing mRNA Decay of a Selective Set of Pro-metastatic Factors.

Cancer cell
2018-12 | Journal article
DOI: 10.1016/j.ccell.2018.11.008
PMID: 30581152
Contributors: Karras P; Riveiro-Falkenbach E; Cañón E; Tejedo C; Calvo TG; Martínez-Herranz R; Alonso-Curbelo D; Cifdaloz M; Perez-Guijarro E; Gómez-López G et al.
Source: Self-asserted source
Panagiotis Karras via Europe PubMed Central
grade
Preferred source (of 2)‎

Toward minimal residual disease-directed therapy in melanoma

2018-10-27 | Lecture
SOURCE-WORK-ID:

2321729
Contributors: florian rambow; A Rogiers; Oskar Marin-Bejar; S Aibar; J Femel; M Dewaele; Panagiotis Karras; D Brown; Young Hwan Chang; Maria Debiec-Rychter et al.
Source: check_circle
KU Leuven

Toward Minimal Residual Disease-Directed Therapy in Melanoma.

Cell
2018-07 | Journal article
DOI: 10.1016/j.cell.2018.06.025
PMID: 30017245
Contributors: Rambow F; Rogiers A; Marin-Bejar O; Aibar S; Femel J; Dewaele M; Karras P; Brown D; Chang YH; Debiec-Rychter M et al.
Source: Self-asserted source
Panagiotis Karras via Europe PubMed Central
grade
Preferred source (of 2)‎

Systems analysis identifies melanoma-enriched pro-oncogenic networks controlled by the RNA binding protein CELF1.

Nature communications
2017-12 | Journal article
DOI: 10.1038/s41467-017-02353-y
PMID: 29269732
PMC: PMC5740069
Contributors: Cifdaloz M; Osterloh L; Graña O; Riveiro-Falkenbach E; Ximénez-Embún P; Muñoz J; Tejedo C; Calvo TG; Karras P; Olmeda D et al.
Source: Self-asserted source
Panagiotis Karras via Europe PubMed Central

Lineage-specific roles of the cytoplasmic polyadenylation factor CPEB4 in the regulation of melanoma drivers.

Nature communications
2016-11 | Journal article
DOI: 10.1038/ncomms13418
PMID: 27857118
PMC: PMC5120223
Contributors: Pérez-Guijarro E; Karras P; Cifdaloz M; Martínez-Herranz R; Cañón E; Graña O; Horcajada-Reales C; Alonso-Curbelo D; Calvo TG; Gómez-López G et al.
Source: Self-asserted source
Panagiotis Karras via Europe PubMed Central

Metastatic risk and resistance to BRAF inhibitors in melanoma defined by selective allelic loss of ATG5.

Autophagy
2016-07 | Journal article
DOI: 10.1080/15548627.2016.1199301
PMID: 27464255
PMC: PMC5079679
Contributors: García-Fernández M; Karras P; Checinska A; Cañón E; Calvo GT; Gómez-López G; Cifdaloz M; Colmenar A; Espinosa-Hevia L; Olmeda D et al.
Source: Self-asserted source
Panagiotis Karras via Europe PubMed Central
grade
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Vascular endothelial-cadherin downregulation as a feature of endothelial transdifferentiation in monocrotaline-induced pulmonary hypertension.

American journal of physiology. Lung cellular and molecular physiology
2016-05 | Journal article
DOI: 10.1152/ajplung.00156.2014
PMID: 27233997
Contributors: Nikitopoulou I; Orfanos SE; Kotanidou A; Maltabe V; Manitsopoulos N; Karras P; Kouklis P; Armaganidis A; Maniatis NA
Source: Self-asserted source
Panagiotis Karras via Europe PubMed Central
grade
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RAB7 counteracts PI3K-driven macropinocytosis activated at early stages of melanoma development.

Oncotarget
2015-05 | Journal article
DOI: 10.18632/oncotarget.4055
PMID: 26008978
PMC: PMC4494909
Contributors: Alonso-Curbelo D; Osterloh L; Cañón E; Calvo TG; Martínez-Herranz R; Karras P; Martínez S; Riveiro-Falkenbach E; Romero PO; Rodríguez-Peralto JL et al.
Source: Self-asserted source
Panagiotis Karras via Europe PubMed Central
grade
Preferred source (of 2)‎

RAB7 controls melanoma progression by exploiting a lineage-specific wiring of the endolysosomal pathway

Cancer Cell
2014-07-14 | Journal article
SOURCE-WORK-ID:

1934575

Part of ISSN: 1535-6108
Contributors: Direna Alonso-Curbelo; Erica Riveiro-Falkenbach; Eva Perez-Guijarro; Metehan Cifdaloz; Karras Panagiotis; Lisa Osterloh; Diego Megias; Estela Cañon; Tonantzin G Calvo; David Olmeda et al.
Source: check_circle
KU Leuven

RAB7 controls melanoma progression by exploiting a lineage-specific wiring of the endolysosomal pathway.

Cancer cell
2014-06 | Journal article
DOI: 10.1016/j.ccr.2014.04.030
PMID: 24981740
Contributors: Alonso-Curbelo D; Riveiro-Falkenbach E; Pérez-Guijarro E; Cifdaloz M; Karras P; Osterloh L; Megías D; Cañón E; Calvo TG; Olmeda D et al.
Source: Self-asserted source
Panagiotis Karras via Europe PubMed Central
grade
Preferred source (of 2)‎

Peer review (4 reviews for 3 publications/grants)

Review activity for Cell death and differentiation. (1)
Review activity for Cell death and disease. (2)
Review activity for Nature communications (1)
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