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Scopus Author ID: 7004351745
ResearcherID: A-4380-2012
SciProfiles: 784775

Countries

Czech Republic

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Employment (1)

Institute of Physiology CAS: Prague, CZ

1983 to present
Employment
Source: Self-asserted source
Viktorie Vlachova

Education and qualifications (1)

Charles University in Prague: Prague, CZ

1977 to 1982
Education
Source: Self-asserted source
Viktorie Vlachova

Works (50 of 87)

Items per page:
Page 1 of 2

Activity dependent inhibition of TRPC1/4/5 channels by duloxetine involves voltage sensor-like domain

Biomedicine and Pharmacotherapy
2022 | Journal article
DOI: 10.1016/j.biopha.2022.113262
EID:

2-s2.0-85132316348

Part of ISSN: 19506007 07533322
Contributors: Zimova, L.; Ptakova, A.; Mitro, M.; Krusek, J.; Vlachova, V.
Source: Self-asserted source
Viktorie Vlachova via Scopus - Elsevier

Cellular context determines primary characteristics of human TRPC5 as a cold-activated channel

Journal of Cellular Physiology
2022 | Journal article
DOI: 10.1002/jcp.30821
EID:

2-s2.0-85132880697

Part of ISSN: 10974652 00219541
Contributors: Ptakova, A.; Mitro, M.; Zimova, L.; Vlachova, V.
Source: Self-asserted source
Viktorie Vlachova via Scopus - Elsevier

Odontoblast TRPC5 channels signal cold pain in teeth

Science Advances
2021 | Journal article
DOI: 10.1126/sciadv.abf5567
EID:

2-s2.0-85103532321

Part of ISSN: 23752548
Contributors: Bernal, L.; Sotelo-Hitschfeld, P.; König, C.; Sinica, V.; Wyatt, A.; Winter, Z.; Hein, A.; Touska, F.; Reinhardt, S.; Tragl, A. et al.
Source: Self-asserted source
Viktorie Vlachova via Scopus - Elsevier

Structural mechanism of heat-induced opening of a temperature-sensitive TRP channel

Nature Structural and Molecular Biology
2021 | Journal article
DOI: 10.1038/s41594-021-00615-4
EID:

2-s2.0-85109966115

Part of ISSN: 15459985 15459993
Contributors: Nadezhdin, K.D.; Neuberger, A.; Trofimov, Y.A.; Krylov, N.A.; Sinica, V.; Kupko, N.; Vlachova, V.; Zakharian, E.; Efremov, R.G.; Sobolevsky, A.I.
Source: Self-asserted source
Viktorie Vlachova via Scopus - Elsevier

The human TRPA1 intrinsic cold and heat sensitivity involves separate channel structures beyond the N-ARD domain

bioRxiv
2021 | Other
DOI: 10.1101/2021.07.31.454589
EID:

2-s2.0-85115108321

Part of ISSN: 26928205
Contributors: Moparthi, L.; Sinica, V.; Filipovic, M.; Vlachova, V.; Zygmunt, P.M.
Source: Self-asserted source
Viktorie Vlachova via Scopus - Elsevier

Transient Receptor Potential Ankyrin 1 Channel: An Evolutionarily Tuned Thermosensor

Physiological Research
2021 | Journal article
DOI: 10.33549/physiolres.934697
EID:

2-s2.0-85112123925

Part of ISSN: 18029973 08628408
Contributors: Sinica, V.; Vlachová, V.
Source: Self-asserted source
Viktorie Vlachova via Scopus - Elsevier

Human and mouse TRPA1 are heat and cold sensors differentially tuned by voltage

Cells
2020 | Journal article
DOI: 10.3390/cells9010057
EID:

2-s2.0-85082723057

Part of ISSN: 20734409
Contributors: Sinica, V.; Zimova, L.; Barvikova, K.; Macikova, L.; Barvik, I.; Vlachova, V.
Source: Self-asserted source
Viktorie Vlachova via Scopus - Elsevier

Proximal C-Terminus Serves as a Signaling Hub for TRPA1 Channel Regulation via Its Interacting Molecules and Supramolecular Complexes

Frontiers in Physiology
2020 | Journal article
DOI: 10.3389/fphys.2020.00189
EID:

2-s2.0-85082690950

Part of ISSN: 1664042X
Contributors: Zimova, L.; Barvikova, K.; Macikova, L.; Vyklicka, L.; Sinica, V.; Barvik, I.; Vlachova, V.
Source: Self-asserted source
Viktorie Vlachova via Scopus - Elsevier

Phospho-Mimetic Mutation at Ser602 Inactivates Human TRPA1 Channel

International Journal of Molecular Sciences
2020-10 | Journal article | Author
DOI: 10.3390/ijms21217995
Contributors: Kristyna Barvikova; Ivan Barvik; Viktor Sinica; Lucie Zimova; Viktorie Vlachova
Source: check_circle
Multidisciplinary Digital Publishing Institute
grade
Preferred source (of 2)‎

Contributions of basic, preclinical and clinical research to the application of induced electrical currents in the indications of rehabilitation and physical medicine,Přínosy základního, preklinického a klinického výzkumu k uplatnění indukovaných elektrických proudů v indikacích rehabilitační a fyzikální medicíny

Rehabilitace a Fyzikalni Lekarstvi
2019 | Journal article
EID:

2-s2.0-85090331555

Part of ISSN: 18054552 12112658
Contributors: Průcha, J.; Dylevský, I.; Navrátil, L.; Vlachová, V.; Krůšek, J.; Dittert, I.; Skopalik, J.; Klapalová, A.; Štengl, M.; Socha, V.
Source: Self-asserted source
Viktorie Vlachova via Scopus - Elsevier

Cytoplasmic inter-subunit interface controls use-dependence of thermal activation of TRPV3 channel

International Journal of Molecular Sciences
2019 | Journal article
DOI: 10.3390/ijms20163990
EID:

2-s2.0-85071477682
Contributors: Macikova, L.; Vyklicka, L.; Barvik, I.; Sobolevsky, A.I.; Vlachova, V.
Source: Self-asserted source
Viktorie Vlachova via Scopus - Elsevier

Putative interaction site for membrane phospholipids controls activation of TRPA1 channel at physiological membrane potentials

FEBS Journal
2019 | Journal article
DOI: 10.1111/febs.14931
EID:

2-s2.0-85067398939
Contributors: Macikova, L.; Sinica, V.; Kadkova, A.; Villette, S.; Ciaccafava, A.; Faherty, J.; Lecomte, S.; Alves, I.D.; Vlachova, V.
Source: Self-asserted source
Viktorie Vlachova via Scopus - Elsevier

Acute exposure to high-induction electromagnetic field affects activity of model peripheral sensory neurons

Journal of Cellular and Molecular Medicine
2018 | Journal article
DOI: 10.1111/jcmm.13423
EID:

2-s2.0-85037333983
Contributors: Prucha, J.; Krusek, J.; Dittert, I.; Sinica, V.; Kadkova, A.; Vlachova, V.
Source: Self-asserted source
Viktorie Vlachova via Scopus - Elsevier

Heat-resistant action potentials require TTXresistant sodium channels Na<inf>V</inf>1.8 and Na<inf>V</inf>1.9

Journal of General Physiology
2018 | Journal article
DOI: 10.1085/jgp.201711786
EID:

2-s2.0-85053845013
Contributors: Touska, F.; Turnquist, B.; Vlachova, V.; Reeh, P.W.; Leffler, A.; Zimmermann, K.
Source: Self-asserted source
Viktorie Vlachova via Scopus - Elsevier

Intracellular cavity of sensor domain controls allosteric gating of TRPA1 channel

Science Signaling
2018 | Journal article
DOI: 10.1126/scisignal.aan8621
EID:

2-s2.0-85041031781
Contributors: Zimova, L.; Sinica, V.; Kadkova, A.; Vyklicka, L.; Zima, V.; Barvik, I.; Vlachova, V.
Source: Self-asserted source
Viktorie Vlachova via Scopus - Elsevier

Molecular basis of TRPA1 regulation in nociceptive neurons. A review

Physiological Research
2017 | Journal article
EID:

2-s2.0-85026394315
Contributors: Kádková, A.; Synytsya, V.; Krusek, J.; Zímová, L.; Vlachová, V.
Source: Self-asserted source
Viktorie Vlachova via Scopus - Elsevier

The first extracellular linker is important for several aspects of the gating mechanism of human TRPA1 channel

Frontiers in Molecular Neuroscience
2017 | Journal article
DOI: 10.3389/fnmol.2017.00016
EID:

2-s2.0-85014040711
Contributors: Marsakova, L.; Barvik, I.; Zima, V.; Zimova, L.; Vlachova, V.
Source: Self-asserted source
Viktorie Vlachova via Scopus - Elsevier

The human transient receptor potential vanilloid 3 channel is sensitized via the ERK pathway

Journal of Biological Chemistry
2017 | Journal article
DOI: 10.1074/jbc.M117.801167
EID:

2-s2.0-85039460535
Contributors: Vyklicka, L.; Boukalova, S.; Macikova, L.; Chvojka, S.; Vlachova, V.
Source: Self-asserted source
Viktorie Vlachova via Scopus - Elsevier

Comprehensive thermal preference phenotyping in mice using a novel automated circular gradient assay

Temperature
2016 | Journal article
DOI: 10.1080/23328940.2015.1135689
EID:

2-s2.0-85026662612
Contributors: Touska, F.; Winter, Z.; Mueller, A.; Vlachova, V.; Larsen, J.; Zimmermann, K.
Source: Self-asserted source
Viktorie Vlachova via Scopus - Elsevier

N-terminal tetrapeptide T/SPLH motifs contribute to multimodal activation of human TRPA1 channel

Scientific Reports
2016 | Journal article
DOI: 10.1038/srep28700
EID:

2-s2.0-84976573602
Contributors: Hynkova, A.; Marsakova, L.; Vaskova, J.; Vlachova, V.
Source: Self-asserted source
Viktorie Vlachova via Scopus - Elsevier

Interaction of a peptide derived from C-terminus of human TRPA1 channel with model membranes mimicking the inner leaflet of the plasma membrane

Biochimica et Biophysica Acta - Biomembranes
2015 | Journal article
DOI: 10.1016/j.bbamem.2015.02.003
EID:

2-s2.0-84923298018
Contributors: Witschas, K.; Jobin, M.-L.; Korkut, D.N.; Vladan, M.M.; Salgado, G.; Lecomte, S.; Vlachova, V.; Alves, I.D.
Source: Self-asserted source
Viktorie Vlachova via Scopus - Elsevier

Structural modeling and patch-clamp analysis of pain-related mutation TRPA1-N855S reveal inter-subunit salt bridges stabilizing the channel open state

Neuropharmacology
2015 | Journal article
DOI: 10.1016/j.neuropharm.2015.02.018
EID:

2-s2.0-84924042089
Contributors: Zíma, V.; Witschas, K.; Hynkova, A.; Zímová, L.; Barvík, I.; Vlachova, V.
Source: Self-asserted source
Viktorie Vlachova via Scopus - Elsevier

Gain-of-function mutations in the transient receptor potential channels TRPV1 and TRPA1: How painful?

Physiological Research
2014 | Journal article
EID:

2-s2.0-84897635350
Contributors: Boukalova, S.; Touska, F.; Marsakova, L.; Hynkova, A.; Sura, L.; Chvojka, S.; Dittert, I.; Vlachova, V.
Source: Self-asserted source
Viktorie Vlachova via Scopus - Elsevier

Gain-of-function mutations in the transient receptor potential channels TRPV1 and TRPA1: How painful?

Physiological Research
2014 | Journal article
EID:

2-s2.0-84919983835
Contributors: Boukalova, S.; Touska, F.; Marsakova, L.; Hynkova, A.; Sura, L.; Chvojka, S.; Dittert, I.; Vlachova, V.
Source: Self-asserted source
Viktorie Vlachova via Scopus - Elsevier

Amplified cold transduction in native nociceptors by M-channel inhibition

Journal of Neuroscience
2013 | Journal article
DOI: 10.1523/JNEUROSCI.1473-13.2013
EID:

2-s2.0-84885445206
Contributors: Vetter, I.; Hein, A.; Sattler, S.; Hessler, S.; Touska, F.; Bressan, E.; Parra, A.; Hager, U.; Leffler, A.; Boukalova, S. et al.
Source: Self-asserted source
Viktorie Vlachova via Scopus - Elsevier

Protons stabilize the closed conformation of gain-of-function mutants of the TRPV1 channel

Biochimica et Biophysica Acta - Molecular Cell Research
2013 | Journal article
DOI: 10.1016/j.bbamcr.2012.11.017
EID:

2-s2.0-84871895296
Contributors: Boukalova, S.; Teisinger, J.; Vlachova, V.
Source: Self-asserted source
Viktorie Vlachova via Scopus - Elsevier

C-terminal acidic cluster is involved in Ca<sup>2+</sup>-induced regulation of human transient receptor potential ankyrin 1 channel

Journal of Biological Chemistry
2012 | Journal article
DOI: 10.1074/jbc.M112.341859
EID:

2-s2.0-84861561860
Contributors: Sura, L.; Zíma, V.; Marsakova, L.; Hynkova, A.; Barvík, I.; Vlachova, V.
Source: Self-asserted source
Viktorie Vlachova via Scopus - Elsevier

Camphor: An effective compound with an unknown mechanism of action,Kafr: Účinná látka s neznámým mechanizmem působení

Bolest
2012 | Journal article
EID:

2-s2.0-84860710535
Contributors: Maršáková, L.; Vlachová, V.
Source: Self-asserted source
Viktorie Vlachova via Scopus - Elsevier

Ciguatoxins activate specific cold pain pathways to elicit burning pain from cooling

EMBO Journal
2012 | Journal article
DOI: 10.1038/emboj.2012.207
EID:

2-s2.0-84867100648
Contributors: Vetter, I.; Touska, F.; Hess, A.; Hinsbey, R.; Sattler, S.; Lampert, A.; Sergejeva, M.; Sharov, A.; Collins, L.S.; Eberhardt, M. et al.
Source: Self-asserted source
Viktorie Vlachova via Scopus - Elsevier

Pore helix domain is critical to camphor sensitivity of transient receptor potential vanilloid 1 channel

Anesthesiology
2012 | Journal article
DOI: 10.1097/ALN.0b013e318249cf62
EID:

2-s2.0-84859108719
Contributors: Marsakova, L.; Touska, F.; Krusek, J.; Vlachova, V.
Source: Self-asserted source
Viktorie Vlachova via Scopus - Elsevier

A "cute" desensitization of TRPV1

Current Pharmaceutical Biotechnology
2011 | Journal article
DOI: 10.2174/138920111793937826
EID:

2-s2.0-78650906660
Contributors: Touska, F.; Marsakova, L.; Teisinger, J.; Vlachova, V.
Source: Self-asserted source
Viktorie Vlachova via Scopus - Elsevier

The C-terminal basic residues contribute to the chemical- and voltage-dependent activation of TRPA1

Biochemical Journal
2011 | Journal article
DOI: 10.1042/BJ20101256
EID:

2-s2.0-79551485942
Contributors: Samad, A.; Sura, L.; Benedikt, J.; Ettrich, R.; Minofar, B.; Teisinger, J.; Vlachova, V.
Source: Self-asserted source
Viktorie Vlachova via Scopus - Elsevier

TRP channels: From understanding to action

Current Pharmaceutical Biotechnology
2011 | Journal article
DOI: 10.2174/138920111793937853
EID:

2-s2.0-78650905551
Contributors: Vlachova, V.
Source: Self-asserted source
Viktorie Vlachova via Scopus - Elsevier

Ankyrin receptor - Ion channel in nociceptive pathways,Ankyrinový receptor - Iontový kanál v nocicepčních drahách

Bolest
2010 | Journal article
EID:

2-s2.0-78049383830
Contributors: Surá, L.; Zíma, V.; Touška, F.; Vlachová, V.
Source: Self-asserted source
Viktorie Vlachova via Scopus - Elsevier

Conserved residues within the putative S4-S5 region serve distinct functions among thermosensitive vanilloid transient receptor potential (TRPV) channels

Journal of Biological Chemistry
2010 | Journal article
DOI: 10.1074/jbc.M110.145466
EID:

2-s2.0-78650638892
Contributors: Boukalova, S.; Marsakova, L.; Teisinger, J.; Vlachova, V.
Source: Self-asserted source
Viktorie Vlachova via Scopus - Elsevier

Basic milestones in the neurophysiological research of pain,Základní mezníky neurofyziologického výzkumu bolesti

Bolest
2009 | Journal article
EID:

2-s2.0-67650351922
Contributors: Vyklický, L.; Vlachová, V.
Source: Self-asserted source
Viktorie Vlachova via Scopus - Elsevier

Essential role for the putative S6 inner pore region in the activation gating of the human TRPA1 channel

Biochimica et Biophysica Acta - Molecular Cell Research
2009 | Journal article
DOI: 10.1016/j.bbamcr.2009.04.014
EID:

2-s2.0-67649400332
Contributors: Benedikt, J.; Samad, A.; Ettrich, R.; Teisinger, J.; Vlachova, V.
Source: Self-asserted source
Viktorie Vlachova via Scopus - Elsevier

Calcium-dependent desensitization of vanilloid receptor TRPV1: A mechanism possibly involved in analgesia induced by topical application of capsaicin

Physiological Research
2008 | Journal article
EID:

2-s2.0-45949105064
Contributors: Vyklický, L.; Nováková-Toušová, K.; Benedikt, J.; Samad, A.; Touška, F.; Vlachova, V.
Source: Self-asserted source
Viktorie Vlachova via Scopus - Elsevier

Calcium-dependent desensitization of vanilloid receptor TRPV1: a mechanism possibly involved in analgesia induced by topical application of capsaicin.

Physiological research / Academia Scientiarum Bohemoslovaca
2008 | Journal article
EID:

2-s2.0-62149140981
Contributors: Vyklický, L.; Nováková-Tousová, K.; Benedikt, J.; Samad, A.; Touska, F.; Vlachová, V.
Source: Self-asserted source
Viktorie Vlachova via Scopus - Elsevier

TRP receptors as transduction molecules of nociceptive stimuli,TRP receptory jako transdukční molekuly nociceptivních podnětů

Bolest
2008 | Journal article
EID:

2-s2.0-58149335332
Contributors: Boukalová, S.; Vlachová, V.
Source: Self-asserted source
Viktorie Vlachova via Scopus - Elsevier

Analgesic effects of capsaicin - 10 Years of searching for molecular mechanisms,Analgetické účinky kapsaicinu - 10 Let hledání molekulárních mechanizmů

Psychiatrie
2007 | Journal article
EID:

2-s2.0-35148871803
Contributors: Toušová, K.; Benedikt, J.; Samad, A.; Vyklický, L.; Vlachová, V.
Source: Self-asserted source
Viktorie Vlachova via Scopus - Elsevier

Analgesic effects of Capsaicin: Mechanism undetermined for thousands of years,Analgetické účinky kapsaicinu: Tisíce let nepoznaný mechanizmus

Bolest
2007 | Journal article
EID:

2-s2.0-35548975180
Contributors: Toušová, K.; Benedikt, J.; Samad, A.; Vyklický, L.; Vlachová, V.
Source: Self-asserted source
Viktorie Vlachova via Scopus - Elsevier

ATP binding site on the C-terminus of the vanilloid receptor

Archives of Biochemistry and Biophysics
2007 | Journal article
DOI: 10.1016/j.abb.2007.06.035
EID:

2-s2.0-34548436165
Contributors: Grycova, L.; Lansky, Z.; Friedlova, E.; Vlachova, V.; Kubala, M.; Obsilova, V.; Obsil, T.; Teisinger, J.
Source: Self-asserted source
Viktorie Vlachova via Scopus - Elsevier

Contribution of the putative inner-pore region to the gating of the transient receptor potential vanilloid subtype 1 channel (TRPV1)

Journal of Neuroscience
2007 | Journal article
DOI: 10.1523/JNEUROSCI.1956-07.2007
EID:

2-s2.0-34447515681
Contributors: Susankova, K.; Ettrich, R.; Vyklicky, L.; Teisinger, J.; Vlachova, V.
Source: Self-asserted source
Viktorie Vlachova via Scopus - Elsevier

Ethanol inhibits cold-menthol receptor TRPM8 by modulating its interaction with membrane phosphatidylinositol 4,5-bisphosphate

Journal of Neurochemistry
2007 | Journal article
DOI: 10.1111/j.1471-4159.2006.04192.x
EID:

2-s2.0-33846169081
Contributors: Benedikt, J.; Teisinger, J.; Vyklicky, L.; Vlachova, V.
Source: Self-asserted source
Viktorie Vlachova via Scopus - Elsevier

Functional changes in the vanilloid receptor subtype 1 channel during and after acute desensitization

Neuroscience
2007 | Journal article
DOI: 10.1016/j.neuroscience.2007.07.039
EID:

2-s2.0-34848889243
Contributors: Novakova-Tousova, K.; Vyklicky, L.; Susankova, K.; Benedikt, J.; Samad, A.; Teisinger, J.; Vlachova, V.
Source: Self-asserted source
Viktorie Vlachova via Scopus - Elsevier

Improved superfusion technique for rapid cooling or heating of cultured cells under patch-clamp conditions

Journal of Neuroscience Methods
2006 | Journal article
DOI: 10.1016/j.jneumeth.2005.07.005
EID:

2-s2.0-33644511744
Contributors: Dittert, I.; Benedikt, J.; Vyklický, L.; Zimmermann, K.; Reeh, P.W.; Vlachová, V.
Source: Self-asserted source
Viktorie Vlachova via Scopus - Elsevier

Molecular mechanisms of the modulation of vanilloid receptor TRPV1,Molekulární mechanizmy modulace vaniloidního receptoru TRPV1

Bolest
2006 | Journal article
EID:

2-s2.0-35549000957
Contributors: Sušánková, K.; Vlachová, V.
Source: Self-asserted source
Viktorie Vlachova via Scopus - Elsevier

Reducing and oxidizing agents sensitize heat-activated vanilloid receptor (TRPV1) current

Molecular Pharmacology
2006 | Journal article
DOI: 10.1124/mol.106.023069
EID:

2-s2.0-33745263762
Contributors: Susankova, K.; Tousova, K.; Vyklicky, L.; Teisinger, J.; Vlachova, V.
Source: Self-asserted source
Viktorie Vlachova via Scopus - Elsevier

Gadolinium activates and sensitizes the vanilloid receptor TRPV1 through the external protonation sites

Molecular and Cellular Neuroscience
2005 | Journal article
DOI: 10.1016/j.mcn.2005.07.004
EID:

2-s2.0-24944546513
Contributors: Tousova, K.; Vyklicky, L.; Susankova, K.; Benedikt, J.; Vlachova, V.
Source: Self-asserted source
Viktorie Vlachova via Scopus - Elsevier
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Peer review (15 reviews for 9 publications/grants)

Review activity for Biomolecules. (1)
Review activity for Communications biology. (1)
Review activity for Heliyon. (1)
Review activity for International journal of molecular sciences. (5)
Review activity for Life sciences. (2)
Review activity for Life. (1)
Review activity for Molecules. (2)
Review activity for Nature communications (1)
Review activity for PloS one. (1)
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