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ResearcherID: G-2945-2017
Scopus Author ID: 6603933256

Keywords

Wnt signaling, stem cells, mammary gland

Countries

Netherlands

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Employment (6)

University of Amsterdam: Amsterdam, Noord-Holland, NL

2017-02 to present | Associate professor (tenured) (Swammerdam Institute for Life Sciences)
Employment
Source: Self-asserted source
Renée van Amerongen

University of Amsterdam: Amsterdam, NL

2013-11 to 2017-01 | Macgillavry fellow and assistant professor (Swammerdam Institute for Life Sciences)
Employment
Source: Self-asserted source
Renée van Amerongen

Netherlands Cancer Institute: Amsterdam, NL

2011-11 to 2013-10 | Senior postdoc
Employment
Source: Self-asserted source
Renée van Amerongen

Stanford University: Stanford, CA, US

2008-01 to 2011-08 | postdoctoral fellow with Roel Nusse
Employment
Source: Self-asserted source
Renée van Amerongen

Netherlands Cancer Institute: Amsterdam, NL

2005-11 to 2007-12 | postdoctoral fellow with Anton Berns
Employment
Source: Self-asserted source
Renée van Amerongen

Netherlands Cancer Institute: Amsterdam, NL

1999-10 to 2005-11-15 | PhD student with Anton Berns
Employment
Source: Self-asserted source
Renée van Amerongen

Education and qualifications (2)

University of Amsterdam: Amsterdam, NL

1999 to 2005 | PhD
Education
Source: Self-asserted source
Renée van Amerongen

Vrije Universiteit Amsterdam: Amsterdam, NL

1994 to 1999 | MSc
Education
Source: Self-asserted source
Renée van Amerongen

Works (50 of 59)

Items per page:
Page 1 of 2

Convergent deployment of ancestral functions during the evolution of mammalian flight membranes

Science Advances
2023 | Journal article
DOI: 10.1126/sciadv.ade7511
EID:

2-s2.0-85150945552

Part of ISSN: 23752548
Contributors: Feigin, C.Y.; Moreno, J.A.; Ramos, R.; Mereby, S.A.; Alivisatos, A.; Wang, W.; Van Amerongen, R.; Camacho, J.; Rasweiler, J.J.; Behringer, R.R. et al.
Source: Self-asserted source
Renée van Amerongen via Scopus - Elsevier

Visualizing WNT signaling in mammalian systems

Current Topics in Developmental Biology
2023 | Book chapter
DOI: 10.1016/bs.ctdb.2023.02.001
EID:

2-s2.0-85150351351

Part of ISSN: 00702153
Contributors: van der Wal, T.; van Amerongen, R.
Source: Self-asserted source
Renée van Amerongen via Scopus - Elsevier

Convergent deployment of ancestral programs during the evolution of mammalian flight membranes

bioRxiv
2022 | Other
DOI: 10.1101/2022.12.06.518272
EID:

2-s2.0-85146561507

Part of ISSN: 26928205
Contributors: Feigin, C.Y.; Moreno, J.A.; Ramos, R.; Mereby, S.A.; Alivisatos, A.; Wang, W.; van Amerongen, R.; Camacho, J.; Rasweiler, J.J.; Behringer, R.R. et al.
Source: Self-asserted source
Renée van Amerongen via Scopus - Elsevier

Erratum: MEIS-WNT5A axis regulates development of fourth ventricle choroid plexus (Development (Cambridge) (2021) 148 (dev192054 ) DOI: 10.1242/dev.192054)

Development (Cambridge)
2022 | Journal article
DOI: 10.1242/dev.200517
EID:

2-s2.0-85123974811

Part of ISSN: 14779129 09501991
Contributors: Kaiser, K.; Jang, A.; Kompanikova, P.; Lun, M.P.; Prochazka, J.; Machon, O.; Dani, N.; Prochazkova, M.; Laurent, B.; Gyllborg, D. et al.
Source: Self-asserted source
Renée van Amerongen via Scopus - Elsevier

Behind the Scenes of the Human Breast Cell Atlas Project

Journal of Mammary Gland Biology and Neoplasia
2021 | Journal article
DOI: 10.1007/s10911-021-09482-7
EID:

2-s2.0-85105442313

Part of ISSN: 15737039 10833021
Contributors: van Amerongen, R.
Source: Self-asserted source
Renée van Amerongen via Scopus - Elsevier

Connecting the Dots: Mammary Gland and Breast Cancer at Single Cell Resolution

Journal of Mammary Gland Biology and Neoplasia
2021 | Journal article
DOI: 10.1007/s10911-021-09492-5
EID:

2-s2.0-85107896864

Part of ISSN: 15737039 10833021
Contributors: van Amerongen, R.; Kordon, E.C.; Koledova, Z.
Source: Self-asserted source
Renée van Amerongen via Scopus - Elsevier

Hyperactive WNT/CTNNB1 signaling induces a competing cell proliferation and epidermal differentiation response in the mouse mammary epithelium

bioRxiv
2021 | Other
DOI: 10.1101/2021.06.22.449461
EID:

2-s2.0-85111238291

Part of ISSN: 26928205
Contributors: Mourao, L.; Zeeman, A.L.; Wiese, K.E.; Bongaarts, A.; Oudejans, L.L.; Martinez, I.M.; van de Grift, Y.B.C.; Jonkers, J.; van Amerongen, R.
Source: Self-asserted source
Renée van Amerongen via Scopus - Elsevier

MEIS-WNT5A axis regulates development of fourth ventricle choroid plexus

Development (Cambridge)
2021 | Journal article
DOI: 10.1242/DEV.192054
EID:

2-s2.0-85106965786

Part of ISSN: 14779129 09501991
Contributors: Kaiser, K.; Jang, A.; Kompanikova, P.; Lun, M.P.; Prochazka, J.; Machon, O.; Dani, N.; Prochazkova, M.; Laurent, B.; Gyllborg, D. et al.
Source: Self-asserted source
Renée van Amerongen via Scopus - Elsevier

Quantitative live-cell imaging and computational modelling shed new light on endogenous wnt/ctnnb1 signaling dynamics

eLife
2021 | Journal article
DOI: 10.7554/eLife.66440
EID:

2-s2.0-85108894992

Part of ISSN: 2050084X
Contributors: de Man, S.M.A.; Zwanenburg, G.; van der Wal, T.; Hink, M.A.; van Amerongen, R.
Source: Self-asserted source
Renée van Amerongen via Scopus - Elsevier

Zooming in on the WNT/CTNNB1 Destruction Complex: Functional Mechanistic Details with Implications for Therapeutic Targeting

Handbook of Experimental Pharmacology
2021 | Book chapter
DOI: 10.1007/164_2021_522
EID:

2-s2.0-85118550377

Part of ISSN: 18650325 01712004
Contributors: de Man, S.M.A.; van Amerongen, R.
Source: Self-asserted source
Renée van Amerongen via Scopus - Elsevier

A novel Axin2 knock-in mouse model for visualization and lineage tracing of WNT/CTNNB1 responsive cells

bioRxiv
2020 | Other
DOI: 10.1101/2020.04.03.024182
EID:

2-s2.0-85098895577

Part of ISSN: 26928205
Contributors: van de Moosdijk, A.A.A.; van de Grift, Y.B.C.; de Man, S.M.A.; Zeeman, A.L.; van Amerongen, R.
Source: Self-asserted source
Renée van Amerongen via Scopus - Elsevier

A novel Axin2 knock-in mouse model for visualization and lineage tracing of WNT/CTNNB1 responsive cells

Genesis
2020 | Journal article
DOI: 10.1002/dvg.23387
EID:

2-s2.0-85087688208

Part of ISSN: 1526968X 1526954X
Contributors: van de Moosdijk, A.A.A.; van de Grift, Y.B.C.; de Man, S.M.A.; Zeeman, A.L.; van Amerongen, R.
Source: Self-asserted source
Renée van Amerongen via Scopus - Elsevier

Aberrant WNT/CTNNB1 Signaling as a Therapeutic Target in Human Breast Cancer: Weighing the Evidence

Frontiers in Cell and Developmental Biology
2020 | Journal article
DOI: 10.3389/fcell.2020.00025
EID:

2-s2.0-85079500904

Part of ISSN: 2296634X
Contributors: van Schie, E.H.; van Amerongen, R.
Source: Self-asserted source
Renée van Amerongen via Scopus - Elsevier

Celebrating Discoveries in Wnt Signaling: How One Man Gave Wings to an Entire Field

Cell
2020 | Journal article
DOI: 10.1016/j.cell.2020.03.033
EID:

2-s2.0-85083760901

Part of ISSN: 10974172 00928674
Contributors: van Amerongen, R.
Source: Self-asserted source
Renée van Amerongen via Scopus - Elsevier

How to Use Online Tools to Generate New Hypotheses for Mammary Gland Biology Research: A Case Study for Wnt7b

Journal of Mammary Gland Biology and Neoplasia
2020 | Journal article
DOI: 10.1007/s10911-020-09474-z
EID:

2-s2.0-85099831323

Part of ISSN: 15737039 10833021
Contributors: van de Grift, Y.B.C.; Heijmans, N.; van Amerongen, R.
Source: Self-asserted source
Renée van Amerongen via Scopus - Elsevier

MEIS-WNT5A axis regulates development of 4<sup>th</sup> ventricle choroid plexus

bioRxiv
2020 | Other
DOI: 10.1101/2020.05.07.082370
EID:

2-s2.0-85102724546

Part of ISSN: 26928205
Contributors: Kaiser, K.; Jang, A.; Lun, M.P.; Procházka, J.; Machon, O.; Procházková, M.; Laurent, B.; Gyllborg, D.; van Amerongen, R.; Kompaníková, P. et al.
Source: Self-asserted source
Renée van Amerongen via Scopus - Elsevier

Quantitative live-cell imaging yields novel insight into endogenous WNT/CTNNB1 signaling dynamics

bioRxiv
2020 | Other
DOI: 10.1101/2020.05.28.120543
EID:

2-s2.0-85098905600

Part of ISSN: 26928205
Contributors: de Man, S.M.A.; Zwanenburg, G.; Hink, M.A.; van Amerongen, R.
Source: Self-asserted source
Renée van Amerongen via Scopus - Elsevier

TMEM98 is a negative regulator of FRAT mediated Wnt/ß-catenin signalling

PLoS ONE
2020 | Journal article
DOI: 10.1371/journal.pone.0227435
EID:

2-s2.0-85078150084

Part of ISSN: 19326203
Contributors: van der Wal, T.; Lambooij, J.-P.; van Amerongen, R.
Source: Self-asserted source
Renée van Amerongen via Scopus - Elsevier

Walking the tight wire between cell adhesion and WNT signalling: A balancing act for β-catenin: A balancing act for CTNNB1

Open Biology
2020 | Journal article
DOI: 10.1098/rsob.200267
EID:

2-s2.0-85097515055

Part of ISSN: 20462441
Contributors: Van Der Wal, T.; Van Amerongen, R.
Source: Self-asserted source
Renée van Amerongen via Scopus - Elsevier

TMEM98 is a negative regulator of FRAT mediated Wnt/β-catenin signalling

bioRxiv
2019 | Other
DOI: 10.1101/512426
EID:

2-s2.0-85092831571

Part of ISSN: 26928205
Contributors: van der Wal, T.; Lambooij, J.-P.; van Amerongen, R.
Source: Self-asserted source
Renée van Amerongen via Scopus - Elsevier

Wnt signalling: Conquering complexity

Development (Cambridge)
2018 | Journal article
DOI: 10.1242/dev.165902
EID:

2-s2.0-85049257560

Part of ISSN: 14779129 09501991
Contributors: Wiese, K.E.; Nusse, R.; van Amerongen, R.
Source: Self-asserted source
Renée van Amerongen via Scopus - Elsevier

Lineage tracing of mammary stem and progenitor cells

Methods in Molecular Biology
2017 | Book chapter
DOI: 10.1007/978-1-4939-6475-8_15
EID:

2-s2.0-84994259877

Part of ISSN: 10643745
Contributors: van de Moosdijk, A.A.A.; Fu, N.Y.; Rios, A.C.; Visvader, J.E.; van Amerongen, R.
Source: Self-asserted source
Renée van Amerongen via Scopus - Elsevier

Complexity galore: 3D cultures, biomechanics and systems medicine at the eighth ENBDC workshop "Methods in Mammary Gland Development and Cancer"

Breast Cancer Research
2016 | Journal article
DOI: 10.1186/s13058-016-0777-2
EID:

2-s2.0-84997077987

Part of ISSN: 1465542X 14655411
Contributors: Lloyd-Lewis, B.; van de Moosdijk, A.A.A.; Bentires-Alj, M.; Clarke, R.B.; van Amerongen, R.
Source: Self-asserted source
Renée van Amerongen via Scopus - Elsevier

Construction and Experimental Validation of a Petri Net Model of Wnt/β-Catenin Signaling.

2016 | Journal article
DOI: 10.1371/journal.pone.0155743
PMID: 27218469
Contributors: Jacobsen A; Heijmans N; Verkaar F; Smit MJ; Heringa J; van Amerongen R; Feenstra KA
Source: Self-asserted source
Renée van Amerongen via Europe PubMed Central
grade
Preferred source (of 2)‎

Generating Cellular Diversity and Spatial Form: Wnt Signaling and the Evolution of Multicellular Animals

Developmental Cell
2016 | Journal article
DOI: 10.1016/j.devcel.2016.08.011
EID:

2-s2.0-84991780814

Part of ISSN: 18781551 15345807
Contributors: Loh, K.M.; van Amerongen, R.; Nusse, R.
Source: Self-asserted source
Renée van Amerongen via Scopus - Elsevier

Identification of reliable reference genes for qRT-PCR studies of the developing mouse mammary gland

Scientific Reports
2016 | Journal article
DOI: 10.1038/srep35595
EID:

2-s2.0-84992080127

Part of ISSN: 20452322
Contributors: Van De Moosdijk, A.A.A.; Van Amerongen, R.
Source: Self-asserted source
Renée van Amerongen via Scopus - Elsevier

PTEN Loss in E-Cadherin-Deficient Mouse Mammary Epithelial Cells Rescues Apoptosis and Results in Development of Classical Invasive Lobular Carcinoma

Cell Reports
2016 | Journal article
DOI: 10.1016/j.celrep.2016.07.059
EID:

2-s2.0-84981719749

Part of ISSN: 22111247
Contributors: Boelens, M.C.; Nethe, M.; Klarenbeek, S.; de Ruiter, J.R.; Schut, E.; Bonzanni, N.; Zeeman, A.L.; Wientjens, E.; van der Burg, E.; Wessels, L. et al.
Source: Self-asserted source
Renée van Amerongen via Scopus - Elsevier

Lineage Tracing in the Mammary Gland Using Cre/lox Technology and Fluorescent Reporter Alleles.

2015 | Journal article
DOI: 10.1007/978-1-4939-2519-3_11
PMID: 26040689
Contributors: van Amerongen R
Source: Self-asserted source
Renée van Amerongen via Europe PubMed Central
grade
Preferred source (of 2)‎

The seventh ENBDC workshop on methods in mammary gland development and cancer.

2015 | Journal article
DOI: 10.1186/s13058-015-0629-5
PMID: 26330220
PMC: PMC4557821
Contributors: Glukhova MA; Hynes N; Vivanco Md; van Amerongen R; Clarke RB; Bentires-Alj M
Source: Self-asserted source
Renée van Amerongen via Europe PubMed Central
grade
Preferred source (of 2)‎

Bipotent mammary stem cells: now in amazing 3D.

2014 | Journal article
DOI: 10.1186/s13058-014-0480-0
PMID: 25927976
PMC: PMC4429940
Contributors: van Amerongen R
Source: Self-asserted source
Renée van Amerongen via Europe PubMed Central
grade
Preferred source (of 2)‎

The influence of tamoxifen on normal mouse mammary gland homeostasis.

2014 | Journal article
DOI: 10.1186/s13058-014-0411-0
PMID: 25056669
PMC: PMC4303226
Contributors: Shehata M; van Amerongen R; Zeeman AL; Giraddi RR; Stingl J
Source: Self-asserted source
Renée van Amerongen via Europe PubMed Central
grade
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Phenotype switching: tumor cell plasticity as a resistance mechanism and target for therapy.

2014-11 | Journal article
DOI: 10.1158/0008-5472.CAN-14-1174
PMID: 25320006
Contributors: Kemper K; de Goeje PL; Peeper DS; van Amerongen R
Source: Self-asserted source
Renée van Amerongen via Europe PubMed Central
grade
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In vivo clonal analysis reveals lineage-restricted progenitor characteristics in mammalian kidney development, maintenance, and regeneration.

2014-05 | Journal article
DOI: 10.1016/j.celrep.2014.04.018
PMID: 24835991
PMC: PMC4425291
Contributors: Rinkevich Y; Montoro DT; Contreras-Trujillo H; Harari-Steinberg O; Newman AM; Tsai JM; Lim X; Van-Amerongen R; Bowman A; Januszyk M et al.
Source: Self-asserted source
Renée van Amerongen via Europe PubMed Central
grade
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The role of Ryk and Ror receptor tyrosine kinases in Wnt signal transduction.

2014-02 | Journal article
DOI: 10.1101/cshperspect.a009175
PMID: 24370848
PMC: PMC3941236
Contributors: Green J; Nusse R; van Amerongen R
Source: Self-asserted source
Renée van Amerongen via Europe PubMed Central
grade
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Erratum: Transient, afferent input-dependent, postnatal niche for neural progenitor cells in the cochlear nucleus (Proceedings of the National Academy of Sciences of the United States of America (2013) 110 (14456-14461) DOI: 10.1073/pnas.1307376110)

Proceedings of the National Academy of Sciences of the United States of America
2013 | Journal article
DOI: 10.1073/pnas.1317787110
EID:

2-s2.0-84885726784

Part of ISSN: 00278424 10916490
Contributors: Volkenstein, S.; Oshima, K.; Sinkkonen, S.T.; Corrales, C.E.; Most, S.P.; Chai, R.; Jan, T.A.; Van Amerongen, R.; Cheng, A.G.; Heller, S.
Source: Self-asserted source
Renée van Amerongen via Scopus - Elsevier

Interfollicular epidermal stem cells self-renew via autocrine Wnt signaling.

2013-12 | Journal article
DOI: 10.1126/science.1239730
PMID: 24311688
PMC: PMC4081860
Contributors: Lim X; Tan SH; Koh WL; Chau RM; Yan KS; Kuo CJ; van Amerongen R; Klein AM; Nusse R
Source: Self-asserted source
Renée van Amerongen via Europe PubMed Central
grade
Preferred source (of 2)‎

Transient, afferent input-dependent, postnatal niche for neural progenitor cells in the cochlear nucleus.

2013-08 | Journal article
DOI: 10.1073/pnas.1307376110
PMID: 23940359
PMC: PMC3761577
Contributors: Volkenstein S; Oshima K; Sinkkonen ST; Corrales CE; Most SP; Chai R; Jan TA; van Amerongen R; Cheng AG; Heller S
Source: Self-asserted source
Renée van Amerongen via Europe PubMed Central

Break the loop, escape the cycle?

2013-07 | Journal article
DOI: 10.1038/emboj.2013.137
PMID: 23749211
PMC: PMC3715859
Contributors: van Amerongen R; Berns A
Source: Self-asserted source
Renée van Amerongen via Europe PubMed Central
grade
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Lineage tracing with Axin2 reveals distinct developmental and adult populations of Wnt/β-catenin-responsive neural stem cells.

2013-04 | Journal article
DOI: 10.1073/pnas.1305411110
PMID: 23589866
PMC: PMC3645553
Contributors: Bowman AN; van Amerongen R; Palmer TD; Nusse R
Source: Self-asserted source
Renée van Amerongen via Europe PubMed Central
grade
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Tympanic border cells are Wnt-responsive and can act as progenitors for postnatal mouse cochlear cells.

2013-03 | Journal article
DOI: 10.1242/dev.087528
PMID: 23444352
PMC: PMC3585657
Contributors: Jan TA; Chai R; Sayyid ZN; van Amerongen R; Xia A; Wang T; Sinkkonen ST; Zeng YA; Levin JR; Heller S et al.
Source: Self-asserted source
Renée van Amerongen via Europe PubMed Central
grade
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Alternative Wnt pathways and receptors.

2012 | Journal article
DOI: 10.1101/cshperspect.a007914
PMID: 22935904
PMC: PMC3475174
Contributors: van Amerongen R
Source: Self-asserted source
Renée van Amerongen via Europe PubMed Central
grade
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Celebrating 30 years of Wnt signaling.

2012-12 | Journal article
DOI: 10.1126/scisignal.2003714
PMID: 23233527
Contributors: Verkaar F; Cadigan KM; van Amerongen R
Source: Self-asserted source
Renée van Amerongen via Europe PubMed Central
grade
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Frat2 mediates the oncogenic activation of Rac by MLL fusions.

2012-12 | Journal article
DOI: 10.1182/blood-2012-05-432534
PMID: 23074275
Contributors: Walf-Vorderwülbecke V; de Boer J; Horton SJ; van Amerongen R; Proost N; Berns A; Williams O
Source: Self-asserted source
Renée van Amerongen via Europe PubMed Central
grade
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Developmental stage and time dictate the fate of Wnt/β-catenin-responsive stem cells in the mammary gland.

2012-09 | Journal article
DOI: 10.1016/j.stem.2012.05.023
PMID: 22863533
Contributors: van Amerongen R; Bowman AN; Nusse R
Source: Self-asserted source
Renée van Amerongen via Europe PubMed Central
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Wnt5a can both activate and repress Wnt/β-catenin signaling during mouse embryonic development.

2012-09 | Journal article
DOI: 10.1016/j.ydbio.2012.06.020
PMID: 22771246
PMC: PMC3435145
Contributors: van Amerongen R; Fuerer C; Mizutani M; Nusse R
Source: Self-asserted source
Renée van Amerongen via Europe PubMed Central
grade
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Frat oncoproteins act at the crossroad of canonical and noncanonical Wnt-signaling pathways

Oncogene
2010 | Journal article
DOI: 10.1038/onc.2009.310
EID:

2-s2.0-73849115661

Part of ISSN: 09509232 14765594
Contributors: Van Amerongen, R.; Nawijn, M.C.; Lambooij, J.-P.; Proost, N.; Jonkers, J.; Berns, A.
Source: Self-asserted source
Renée van Amerongen via Scopus - Elsevier

Towards an integrated view of Wnt signaling in development.

2009-10 | Journal article
DOI: 10.1242/dev.033910
PMID: 19736321
Contributors: van Amerongen R; Nusse R
Source: Self-asserted source
Renée van Amerongen via Europe PubMed Central
grade
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Alternative wnt signaling is initiated by distinct receptors.

2008 | Journal article
DOI: 10.1126/scisignal.135re9
PMID: 18765832
Contributors: van Amerongen R; Mikels A; Nusse R
Source: Self-asserted source
Renée van Amerongen via Europe PubMed Central
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Targeted Anticancer Therapies: Mouse Models Help Uncover the Mechanisms of Tumor Escape (DOI:10.1016/j.ccr.2007.12.019)

Cancer Cell
2008 | Journal article
DOI: 10.1016/j.ccr.2008.02.012
EID:

2-s2.0-39849098910

Part of ISSN: 15356108
Contributors: van Amerongen, R.; Berns, A.
Source: Self-asserted source
Renée van Amerongen via Scopus - Elsevier

Targeted anticancer therapies: mouse models help uncover the mechanisms of tumor escape.

2008-01 | Journal article
DOI: 10.1016/j.ccr.2007.12.019
PMID: 18167334
Contributors: van Amerongen R; Berns A
Source: Self-asserted source
Renée van Amerongen via Europe PubMed Central
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Peer review (20 reviews for 12 publications/grants)

Review activity for Cell stem cell. (2)
Review activity for Cell. (2)
Review activity for Cells and development. (1)
Review activity for Communications biology. (1)
Review activity for Developmental cell. (1)
Review activity for eLife (2)
Review activity for Journal of mammary gland biology and neoplasia. (5)
Review activity for Nature (1)
Review activity for Nature cancer. (1)
Review activity for Nature communications (2)
Review activity for Review Commons (1)
Review activity for Stem cell reports. (1)
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