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SciProfiles: 135825

Keywords

Fat taste, CD36, GPR120, obesity

Countries

France

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Employment (1)

INSERM U1231: Dijon, FR

1997-09-01 to present | Head of the research Team (Physiology)
Employment
Source: Self-asserted source
Naim Akhtar Khan

Education and qualifications (3)

Université de Limoges: Limoges, Nouvelle-Aquitaine, FR

1993 to 1995 | Habilitation à Diriger la Recherche (HDR)
Education
Source: Self-asserted source
Naim Akhtar Khan

Université de Rennes 1: Rennes, Bretagne, FR

1988 to 1993 | DSc
Education
Source: Self-asserted source
Naim Akhtar Khan

Hemwati Nandan Bahuguna Garhwal University: Srinagar, Uttarakhand, IN

1979 to 1983 | PhD
Education
Source: Self-asserted source
Naim Akhtar Khan

Professional activities (7)

The Royal Society Biology: London, London, GB

Fellow
Membership
Source: Self-asserted source
Naim Akhtar Khan

Académie Nationale de Médecine: Paris, Île-de-France, FR

2020-12-15 | Nutrition/Food sciences
Distinction
Source: Self-asserted source
Naim Akhtar Khan

Università degli Studi di Cagliari: Cagliari, Sardegna, IT

2018 | Visiting professor
Invited position
Source: Self-asserted source
Naim Akhtar Khan

Masaryk University: Brno, CZ

2014 | Linnolec Award
Distinction
Source: Self-asserted source
Naim Akhtar Khan

Masaryk University: Brno, CZ

2013 to 2013 | INNOEC Lectureship (Neurobiology)
Invited position
Source: Self-asserted source
Naim Akhtar Khan

Physiological Society FR: Paris, FR

2012 | Nobert Naquet Prize
Distinction
Source: Self-asserted source
Naim Akhtar Khan

Chiba University: Chiba, JP

2011 | Visiting professor
Invited position
Source: Self-asserted source
Naim Akhtar Khan

Works (50 of 54)

Items per page:
Page 1 of 2

Celastrol Improves Preference for a Fatty Acid, and Taste Bud and Systemic Inflammation in Diet-Induced Obese Mice

Nutrients
2025-04 | Journal article | Author
DOI: 10.3390/nu17081308
Contributors: Manal Benmouna; Chahid Benammar; Amira Sayed Khan; Fatima Zohra Djeziri; aziz hichami; Naim Akhtar Khan
Source: check_circle
Multidisciplinary Digital Publishing Institute
grade
Preferred source (of 2)‎

Cardiometabolic Markers in Algerian Obese Subjects with and Without Type 2 Diabetes: Adipocytokine Imbalance as a Risk Factor

Journal of Clinical Medicine
2025-03-06 | Journal article
DOI: 10.3390/jcm14051770
Contributors: Hassiba Benbaibeche; Abdenour Bounihi; Hamza Saidi; Elhadj Ahmed Koceir; Naim Akhtar Khan
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Distinct binding hotspots for natural and synthetic agonists of FFA4 from in silico approaches**

Molecular Informatics
2024-10 | Journal article
DOI: 10.1002/minf.202400046
Contributors: Guillaume Patient; Corentin Bedart; Naim. A Khan; Nicolas Renault; Amaury Farce
Source: check_circle
Crossref

Steviol rebaudiosides bind to four different sites of the human sweet taste receptor (T1R2/T1R3) complex explaining confusing experiments

Communications Chemistry
2024-10-18 | Journal article
DOI: 10.1038/s42004-024-01324-x
Contributors: Shuang Hao; Brian Guthrie; Soo-Kyung Kim; Sergej Balanda; Jan Kubicek; Babar Murtaza; Naim A. Khan; Pouyan Khakbaz; Judith Su; William A. Goddard, III
Source: check_circle
Crossref

Steviol Rebaudiosides bind to four different sites of the human sweet taste receptor (T1R2/T1R3) complex explaining confusing experiments

2024-01-10 | Preprint
DOI: 10.26434/chemrxiv-2024-xklj4
Contributors: Shuang Hao; Brian Guthrie; Soo-Kyung Kim; Sergej Balanda; Jan Kubicek; Babar Murtaza; Naim Khan; Pouyan Khakbaz; Judith Su; William Goddard
Source: check_circle
Crossref

In Vitro Functional Characterization of Type-I Taste Bud Cells as Monocytes/Macrophages-like Which Secrete Proinflammatory Cytokines

International Journal of Molecular Sciences
2023-06-19 | Journal article
DOI: 10.3390/ijms241210325
Contributors: Aziz Hichami; Hamza Saidi; Amira Sayed Khan; Pernelle Degbeni; Naim Akhtar Khan
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Loss of Sour Taste Is the Striking Feature among Four Basic Taste Qualities in Tunisian COVID-19 Patients

Journal of Clinical Medicine
2023-01-11 | Journal article
DOI: 10.3390/jcm12020597
Contributors: Inchirah Karmous; Amira Sayed Khan; Imen Sahnoun; Rym Ben Othman; Houda Ben Jemaa; Faten Mahjoub; Amel Gamoudi; Leila Douik El Gharbi; Tahar Mestiri; Naim Akhtar Khan et al.
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Taste of Fat and Obesity: Different Hypotheses and Our Point of View

Nutrients
2022-01-27 | Journal article
DOI: 10.3390/nu14030555
Contributors: Laurent Brondel; Didier Quilliot; Thomas Mouillot; Naim Akhtar Khan; Philip Bastable; Vincent Boggio; Corinne Leloup; Luc Pénicaud
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Cellular and Molecular Mechanisms of Fat Taste Perception

Handbook of Experimental Pharmacology
2021 | Book chapter
DOI: 10.1007/164_2021_437
Part of ISSN: 0171-2004
Part of ISSN: 1865-0325
Source: Self-asserted source
Naim Akhtar Khan

Tongue Leptin Decreases Oro-Sensory Perception of Dietary Fatty Acids

Nutrients
2021-12 | Journal article | Author
DOI: 10.3390/nu14010197
Contributors: Hameed Ullah; Amira Sayed Khan; Babar Murtaza; aziz hichami; Naim Akhtar Khan
Source: check_circle
Multidisciplinary Digital Publishing Institute
grade
Preferred source (of 2)‎

Management of Childhood Obesity—Time to Shift from Generalized to Personalized Intervention Strategies

Nutrients
2021-04-06 | Journal article
DOI: 10.3390/nu13041200
Part of ISSN: 2072-6643
Source: Self-asserted source
Naim Akhtar Khan
grade
Preferred source (of 3)‎

Zizyphus lotus L. fruit attenuates obesity-associated alterations: in vivo mechanisms

Archives of Physiology and Biochemistry
2021-03-04 | Journal article
DOI: 10.1080/13813455.2019.1621349
Part of ISSN: 1381-3455
Part of ISSN: 1744-4160
Source: Self-asserted source
Naim Akhtar Khan

DHA induces Jurkat T-cell arrest in G2/M phase of cell cycle and modulates the plasma membrane expression of TRPC3/6 channels

Biochimie
2021-02 | Journal article
DOI: 10.1016/j.biochi.2020.12.005
Part of ISSN: 0300-9084
Source: Self-asserted source
Naim Akhtar Khan

Implication of TRPC3 channel in gustatory perception of dietary lipids

Acta Physiologica
2021-02 | Journal article
DOI: 10.1111/apha.13554
Contributors: Babar Murtaza; Aziz Hichami; Amira S. Khan; Jiri Plesnik; Omar Sery; Alexander Dietrich; Lutz Birnbaumer; Naim A. Khan
Source: check_circle
Crossref

Antioxidant and Anti-Inflammatory Potential of Polyphenols Contained in Mediterranean Diet in Obesity: Molecular Mechanisms

Molecules
2021-02-12 | Journal article
DOI: 10.3390/molecules26040985
Contributors: Abdelhafid Nani; Babar Murtaza; Amira Sayed Khan; Naim Akhtar Khan; Aziz Hichami
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Single-nucleotide polymorphism rs1761667 in the CD36 gene is associated with orosensory perception of a fatty acid in obese and normal-weight Moroccan subjects

Journal of Nutritional Science
2020 | Journal article
DOI: 10.1017/jns.2020.18
Part of ISSN: 2048-6790
Source: Self-asserted source
Naim Akhtar Khan

July-December 2020

The North African Journal of Food and Nutrition Research
2020-12-27 | Journal article
DOI: 10.51745/najfnr.4.08.336-342
Contributors: Abdelhafid Nani; Meriem Belarbi; Naim Akhtar Khan; Aziz Hichami
Source: check_circle
Crossref

Nutritional properties and plausible benefits of Pearl millet (Pennisetum glaucum) on bone metabolism and osteoimmunology : a mini-review

The North African Journal of Food and Nutrition Research
2020-12-27 | Journal article
DOI: 10.51745/najfnr.4.8.336-342
Contributors: Abdelhafid Nani; Meriem Belarbi; Naim Akhtar Khan; Aziz Hichami
Source: check_circle
Crossref

Study of Clinical and Biological Characteristics of Moroccan Covid-19 Patients With and Without Olfactory and/or Gustatory Dysfunction

Frontiers in Physiology
2020-11-19 | Journal article
DOI: 10.3389/fphys.2020.595005
Part of ISSN: 1664-042X
Source: Self-asserted source
Naim Akhtar Khan

Anakinra for severe forms of COVID-19

The Lancet Rheumatology
2020-10 | Journal article
DOI: 10.1016/s2665-9913(20)30273-3
Part of ISSN: 2665-9913
Source: Self-asserted source
Naim Akhtar Khan

Obesity and COVID-19: Oro-Naso-Sensory Perception

Journal of Clinical Medicine
2020-07-08 | Journal article
DOI: 10.3390/jcm9072158
Contributors: Amira Sayed Khan; Aziz Hichami; Naim Akhtar Khan
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

CD36 and GPR120 Methylation Associates with Orosensory Detection Thresholds for Fat and Bitter in Algerian Young Obese Children

Journal of Clinical Medicine
2020-06-23 | Journal article
DOI: 10.3390/jcm9061956
Contributors: Moustafa Berrichi; Aziz Hichami; Lynda Addou-Klouche; Amira Sayed Khan; Naim Akhtar Khan
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Circulating mir-21 and mir-146a are associated with increased cytokines and CD36 in Algerian obese male participants

Archives of Physiology and Biochemistry
2020-06-13 | Journal article
DOI: 10.1080/13813455.2020.1775655
Part of ISSN: 1381-3455
Part of ISSN: 1744-4160
Source: Self-asserted source
Naim Akhtar Khan

Preference for dietary fat: From detection to disease

Progress in Lipid Research
2020-04 | Journal article
DOI: 10.1016/j.plipres.2020.101032
Part of ISSN: 0163-7827
Source: Self-asserted source
Naim Akhtar Khan

Spirulina reduces diet-induced obesity through downregulation of lipogenic genes expression inPsammomys obesus

Archives of Physiology and Biochemistry
2020-03-24 | Journal article
DOI: 10.1080/13813455.2020.1743724
Part of ISSN: 1381-3455
Part of ISSN: 1744-4160
Source: Self-asserted source
Naim Akhtar Khan

Bile acid receptor TGR5 is critically involved in preference for dietary lipids and obesity

The Journal of Nutritional Biochemistry
2020-02 | Journal article
DOI: 10.1016/j.jnutbio.2019.108298
Part of ISSN: 0955-2863
Source: Self-asserted source
Naim Akhtar Khan

Novel GPR120 agonist TUG891 modulates fat taste perception and preference and activates tongue-brain-gut axis in mice

Journal of Lipid Research
2020-02-05 | Journal article
DOI: 10.1194/jlr.RA119000142
Contributors: Babar Murtaza; Aziz Hichami; Amira S. Khan; Bharat Shimpukade; Trond Ulven; Mehmet Hakan Ozdener; Naim A. Khan
Source: check_circle
Crossref

Fat Addiction: Psychological and Physiological Trajectory

Nutrients
2019-11-15 | Journal article
DOI: 10.3390/nu11112785
Contributors: Siddharth Sarkar; Kanwal Preet Kochhar; Naim Akhtar Khan
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

A cross-talk between fat and bitter taste modalities

Biochimie
2019-04 | Journal article
DOI: 10.1016/j.biochi.2018.06.013
Part of ISSN: 0300-9084
Source: Self-asserted source
Naim Akhtar Khan

Th1/Th2 Dichotomy in Obese Women with Gestational Diabetes and Their Macrosomic Babies

Journal of Diabetes Research
2018-11-14 | Journal article
DOI: 10.1155/2018/8474617
Contributors: A. Seck; A. Hichami; S. Doucouré; F. Diallo Agne; H. Bassène; A. Ba; C. Sokhna; N. A. Khan; A. Samb
Source: check_circle
Crossref

Oleanolic acid improves diet-induced obesity by modulating fat preference and inflammation in mice

Biochimie
2018-09 | Journal article
DOI: 10.1016/j.biochi.2018.06.025
Part of ISSN: 0300-9084
Source: Self-asserted source
Naim Akhtar Khan

Taste perception and its effects on oral nutritional supplements in younger life phases

Current Opinion in Clinical Nutrition & Metabolic Care
2018-09 | Journal article
DOI: 10.1097/mco.0000000000000492
Part of ISSN: 1363-1950
Source: Self-asserted source
Naim Akhtar Khan

Orosensory Detection of Dietary Fatty Acids Is Altered in CB1R−/− Mice

Nutrients
2018-09-21 | Journal article
DOI: 10.3390/nu10101347
Part of ISSN: 2072-6643
Source: Self-asserted source
Naim Akhtar Khan

Fatty Acid Lingual Application Activates Gustatory and Reward Brain Circuits in the Mouse

Nutrients
2018-09-06 | Journal article
DOI: 10.3390/nu10091246
Part of ISSN: 2072-6643
Source: Self-asserted source
Naim Akhtar Khan

Effect of cadmium exposure on essential omega-3 fatty acids in the edible bivalve Donax trunculus

Environmental Science and Pollution Research
2018-07 | Journal article
DOI: 10.1007/s11356-017-9031-4
Part of ISSN: 0944-1344
Part of ISSN: 1614-7499
Source: Self-asserted source
Naim Akhtar Khan
grade
Preferred source (of 2)‎

Orosensory detection of bitter in fat-taster healthy and obese participants: Genetic polymorphism of CD36 and TAS2R38

Clinical Nutrition
2018-02 | Journal article
DOI: 10.1016/j.clnu.2017.06.004
Part of ISSN: 0261-5614
Source: Self-asserted source
Naim Akhtar Khan

The rs1527483, but not rs3212018, CD36 polymorphism associates with linoleic acid detection and obesity in Czech young adults

British Journal of Nutrition
2018-02-28 | Journal article
DOI: 10.1017/s0007114517003981
Part of ISSN: 0007-1145
Part of ISSN: 1475-2662
Source: Self-asserted source
Naim Akhtar Khan

CD36 gene is associated with intraocular pressure elevation after intravitreal application of anti-VEGF agents in patients with age-related macular degeneration: Implications for the safety of the therapy

Ophthalmic Genetics
2018-01-02 | Journal article
DOI: 10.1080/13816810.2017.1326508
Part of ISSN: 1381-6810
Part of ISSN: 1744-5094
Source: Self-asserted source
Naim Akhtar Khan

Protective effects of polyphenol-rich infusions from carob (Ceratonia siliqua) leaves and cladodes of Opuntia ficus-indica against inflammation associated with diet-induced obesity and DSS-induced colitis in Swiss mice

Biomedicine & Pharmacotherapy
2017-12 | Journal article
DOI: 10.1016/j.biopha.2017.11.125
Part of ISSN: 0753-3322
Source: Self-asserted source
Naim Akhtar Khan

Enteroendocrine L Cells Sense LPS after Gut Barrier Injury to Enhance GLP-1 Secretion

Cell Reports
2017-10 | Journal article
DOI: 10.1016/j.celrep.2017.10.008
Part of ISSN: 2211-1247
Source: Self-asserted source
Naim Akhtar Khan

Zizyphin modulates calcium signalling in human taste bud cells and fat taste perception in the mouse

Fundamental & Clinical Pharmacology
2017-10 | Journal article
DOI: 10.1111/fcp.12289
Contributors: Babar Murtaza; Meryem Berrichi; Chahid Bennamar; Thierry Tordjmann; Fatima Z. Djeziri; Aziz Hichami; Julia Leemput; Meriem Belarbi; Hakan Ozdener; Naim A. Khan
Source: check_circle
Crossref

ERK1 and ERK2 activation modulates diet-induced obesity in mice

Biochimie
2017-06 | Journal article
DOI: 10.1016/j.biochi.2017.03.004
Part of ISSN: 0300-9084
Source: Self-asserted source
Naim Akhtar Khan

CD36 gene polymorphism is associated with Alzheimer's disease

Biochimie
2017-04 | Journal article
DOI: 10.1016/j.biochi.2017.01.009
Part of ISSN: 0300-9084
Source: Self-asserted source
Naim Akhtar Khan

Alteration in Taste Perception in Cancer: Causes and Strategies of Treatment

Frontiers in Physiology
2017-03-08 | Journal article
DOI: 10.3389/fphys.2017.00134
Part of ISSN: 1664-042X
Source: Self-asserted source
Naim Akhtar Khan

The desert gerbil Psammomys obesus as a model for metformin-sensitive nutritional type 2 diabetes to protect hepatocellular metabolic damage: Impact of mitochondrial redox state

PLOS ONE
2017-02-21 | Journal article
DOI: 10.1371/journal.pone.0172053
Part of ISSN: 1932-6203
Source: Self-asserted source
Naim Akhtar Khan
grade
Preferred source (of 2)‎

Phenolic extract from oleaster (Olea europaea var. Sylvestris) leaves reduces colon cancer growth and induces caspase-dependent apoptosis in colon cancer cells via the mitochondrial apoptotic pathway

PLOS ONE
2017-02-17 | Journal article
DOI: 10.1371/journal.pone.0170823
Part of ISSN: 1932-6203
Source: Self-asserted source
Naim Akhtar Khan
grade
Preferred source (of 3)‎

Nutrition: From Bench to Bedside

Journal of Nutrition and Metabolism
2016 | Journal article
DOI: 10.1155/2016/4295179
Part of ISSN: 2090-0724
Part of ISSN: 2090-0732
Source: Self-asserted source
Naim Akhtar Khan

Role of T-Cell Polarization and Inflammation and Their Modulation by n-3 Fatty Acids in Gestational Diabetes and Macrosomia

Journal of Nutrition and Metabolism
2016 | Journal article
DOI: 10.1155/2016/3124960
Part of ISSN: 2090-0724
Part of ISSN: 2090-0732
Source: Self-asserted source
Naim Akhtar Khan

Grape seed and skin extract reduces pancreas lipotoxicity, oxidative stress and inflammation in high fat diet fed rats

Biomedicine & Pharmacotherapy
2016-12 | Journal article
DOI: 10.1016/j.biopha.2016.11.017
Part of ISSN: 0753-3322
Source: Self-asserted source
Naim Akhtar Khan
grade
Preferred source (of 3)‎

Peroxisome proliferator-activated receptor alpha deficiency impairs regulatory T cell functions: Possible application in the inhibition of melanoma tumor growth in mice

Biochimie
2016-12 | Journal article
DOI: 10.1016/j.biochi.2016.09.001
Part of ISSN: 0300-9084
Source: Self-asserted source
Naim Akhtar Khan
grade
Preferred source (of 2)‎
Items per page:
Page 1 of 2

Peer review (7 reviews for 5 publications/grants)

Review activity for Cellular and molecular life sciences (1)
Review activity for Communications biology. (1)
Review activity for Lipids in health and disease (1)
Review activity for Molecules. (1)
Review activity for npj science of food. (3)
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