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Other IDs

ResearcherID: N-2948-2016
Scopus Author ID: 56800932700
Scopus Author ID: 57198456425
Scopus Author ID: 57226366980

Keywords

cancer, nanoparticles, drug delivery, anticancer drugs

Countries

Ukraine

Activities

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Employment (1)

Danylo Halytsky Lviv National Medical University: Lviv, UA

1994-09-03 to present | Professor (Biochemistry)
Employment
Source: Self-asserted source
Lesya Kobylinska

Education and qualifications (1)

Ivan Franko National University of Lviv: Lviv, Lviv, UA

1989-12 to 1994-06 | Biology (Physiology )
Education
Source: Self-asserted source
Lesya Kobylinska

Professional activities (3)

Federation of European Biochemical Societies: Cambridge, GB

2014-08 to present
Membership
Source: Self-asserted source
Lesya Kobylinska

Ukrainian Biochemical Society: Lviv, UA

1994-09 to present (Lviv Division)
Membership
Source: Self-asserted source
Lesya Kobylinska

Ukrainian Physiology Society: Lviv, UA

1994 to present (Biochemistry)
Membership
Source: Self-asserted source
Lesya Kobylinska

Funding (4)

Роль COVID-19 у прогресуванні ендотеліальної дисфункції у пацієнтів з артеріальною гіпертензією, ішемічною хворобою серця і цукровим діабетом

Source: Self-asserted source
Lesya Kobylinska

Glycan biomarkers for posttraumatic stress disorder

2023 to 2025 | Grant
RECOOP HST Association (LA, CA, US)
Source: Self-asserted source
Lesya Kobylinska

Analysis of the vascular endothelial function influencing factors in the blood of high-risk patients with COVID-19-induced metabolic and cardiovascular diseases

2022 to 2026 | Grant
RECOOP HST Association (LA, CA, US)
Source: Self-asserted source
Lesya Kobylinska

Superparamagnetic iron oxide nanoparticles as bio-imaging agent and carrier of anticancer drugs

2016 to 2018 | Grant
RECOOP HST Association (Northridge, LA, US)
GRANT_NUMBER:

#006
Source: Self-asserted source
Lesya Kobylinska

Works (24)

PEG-Polymeric Nanocarriers Alleviate the Immunosuppressive Effects of Free 4-Thiazolidinone-Based Chemotherapeutics on T Lymphocyte Function and Cytokine Production

International Journal of Nanomedicine
2024-12 | Journal article
DOI: 10.2147/IJN.S479137
Contributors: Jana Tulinska; Lesya Kobylinska; Miroslava Lehotska Mikusova; Julia Babincova; Natalia Mitina; Eva Rollerova; Aurelia Liskova; Nikola Madrova; Radka Alacova; Alexander Zaichenko et al.
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Crossref

THE ROLE OF ADIPONECTIN, VISFATIN AND IRISIN IN THE PATHOGENESIS AND TREATMENT OF ARTERIAL HYPERTENSION

Medical Science of Ukraine (MSU)
2024-09-30 | Journal article
DOI: 10.32345/2664-4738.3.2024.04
Contributors: O.T. Romaniuk; H.E. Sklyarova; О.О. Tiutiunnyk; I.S. Fomenko; E.Y. Sklyarov; L.I. Kobylinska; G. VariShandor
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Crossref

УМІСТ АДИПОНЕКТИНУ, ВІСФАТИНУ, TOLL-ПОДІБНОГО РЕЦЕПТОРА-4 І АРГІНАЗИ-ІІ У МЕТАБОЛІЧНО СКОМПРОМЕТОВАНИХ ПАЦІЄНТІВ З АРТЕРІАЛЬНОЮ ГІПЕРТЕНЗІЄЮ

Актуальні проблеми профілактичної медицини
2024-09-10 | Journal article
DOI: 10.32782/2786-9067-2024-27-12
Contributors: O.E. Sklyarova; I.S. Fomenko; L.I. Kobylinska; E.Ya. Sklyarov; S.G. Vari
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Crossref

Galectin-3 in Blood Serum and Lymphocytes as a Marker of Myocardial Damage in Patients with Arterial Hypertension and COVID-19

Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry
2023-12 | Journal article
DOI: 10.2174/0118715230273606231103075632
Contributors: Nataliia Pokrovska; Nataliia Denysenko; Iryna Fomenko; Helen Sklyarova; Andrii Basylevych; Eugene Sklyarov; Sandor G. Vari; Lesya Kobylinska
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Crossref

Mentha piperita: Essential Oil and Extracts, Their Biological Activities, and Perspectives on the Development of New Medicinal and Cosmetic Products

Molecules
2023-11-06 | Journal article
DOI: 10.3390/molecules28217444
Contributors: Nataliia Hudz; Lesya Kobylinska; Katarzyna Pokajewicz; Vladimira Horčinová Sedláčková; Roman Fedin; Mariia Voloshyn; Iryna Myskiv; Ján Brindza; Piotr Paweł Wieczorek; Jacek Lipok
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Crossref
grade
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METHODICAL APPROACH TO THE DETERMINATION OF THE ANTIOXIDANT ACTIVITY OF THE ECHINACEA PURPUREA AND MONARDA FISTULOSA TINCTURES AS A QUALITY CRITERION OF THE DEVELOPMENT OF THEIR COMPOSITION AND LABORATORY TECHNOLOGY

Acta Medica Leopoliensia
2022-06-30 | Journal article
DOI: 10.25040/aml2022.1-2.089
Contributors: Oksana Yezerska; Nataliia Hudz; Lesya Kobylinska; Anna Filipska; Vira Turkina; Jan Brindza; Piotr Pawel Wieczorek
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Crossref

LIFE DEVOTED TO SCIENCE (on the occasion of Prof. Rostyslav Stoyka’s anniversary)

Proceedings of the Shevchenko Scientific Society. Medical Sciences
2020-07-01 | Journal article
DOI: 10.25040/ntsh2020.01.18
Contributors: Lesya Kobylinska
Source: check_circle
Crossref

Biodistribution and Anticancer Characteristics of Les-3833, A Novel 4-thiazolidinone-Based Lead Compound

Scientia Pharmaceutica
2020-03-30 | Journal article
DOI: 10.3390/scipharm88020018
Contributors: Lesya Kobylinska; Andrii Lozynskii; Roman Lesyk; Rostyslav Stoika; Sandor G. Vari
Source: check_circle
Crossref
grade
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Targeting of the pro-oxidant-antioxidant balance in vitro and in vivo by 4-thiazolidinone-based chemotherapeutics with anticancer potential

Ukrainian Biochemical Journal
2019 | Journal article
DOI: 10.15407/ubj91.02.007
EID:

2-s2.0-85069660159
Contributors: Kobylinska, L.; Klyuchivska, O.; Lesyk, R.; Stoika, R.
Source: Self-asserted source
Lesya Kobylinska via Scopus - Elsevier

Enhanced Proapoptotic Effects of Water Dispersed Complexes of 4-Thiazolidinone-Based Chemotherapeutics with a PEG-Containing Polymeric Nanocarrier

Nanoscale Research Letters
2019-12 | Journal article
DOI: 10.1186/s11671-019-2945-7
Contributors: L. Kobylinska; I. Ivasechko; N. Skorokhyd; R. Panchuk; A. Riabtseva; N. Mitina; A. Zaichenko; R. Lesyk; B. Zimenkovsky; R. Stoika et al.
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Crossref
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Biological and analytical studies of peritoneal dialysis solutions

Ukrainian Biochemical Journal
2018 | Journal article
DOI: 10.15407/ubj90.02.034
EID:

2-s2.0-85045508442
Contributors: Hudz, N.; Kobylinska, L.; Dmytrukha, N.; Korytniuk, R.; Wieczorek, P.P.
Source: Self-asserted source
Lesya Kobylinska via Scopus - Elsevier

Increased antitumor efficiency and reduced negative side effects of 4-thiazolidinone derivatives in complexes with PEG-containing polymeric nanocarrier

Biopolymers and Cell
2018 | Journal article
DOI: 10.7124/bc.000985
EID:

2-s2.0-85059518555
Contributors: Kobylinska, L.I.; Skorohyd, N.R.; Klyuchivska, O.V.; Mitina, N.Y.; Zaichenko, A.S.; Lesyk, R.B.; Zimenkovsky, B.S.; Stoika, R.S.
Source: Self-asserted source
Lesya Kobylinska via Scopus - Elsevier

Comb-like PEG-containing polymeric composition as low toxic drug nanocarrier

Cancer Nanotechnology
2018-12 | Journal article
DOI: 10.1186/s12645-018-0045-5
Contributors: Lesya Kobylinska; Igor Patereha; Natalia Finiuk; Natalia Mitina; Anna Riabtseva; Igor Kotsyumbas; Rostyslav Stoika; Alexander Zaichenko; Sandor G. Vari
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Crossref
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Cytotoxicity of doxorubicin-conjugated poly[N-(2-hydroxypropyl)methacrylamide]-modified γ-Fe2O3 nanoparticles towards human tumor cells

Beilstein Journal of Nanotechnology
2018-09-25 | Journal article
DOI: 10.3762/bjnano.9.236
Contributors: Zdeněk Plichta; Yulia Kozak; Rostyslav Panchuk; Viktoria Sokolova; Matthias Epple; Lesya Kobylinska; Pavla Jendelová; Daniel Horák
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Crossref
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4-Thiazolidinone derivative Les-3833 effectively inhibits viability of human melanoma cells through activating apoptotic mechanisms

Croatian Medical Journal
2017 | Journal article
DOI: 10.3325/cmj.2017.58.129
EID:

2-s2.0-85017540842
Contributors: Finiuk, N.; Boiko, N.; Klyuchivska, O.; Kobylinska, L.; Kril, I.; Zimenkovsky, B.; Lesyk, R.; Stoika, R.
Source: Self-asserted source
Lesya Kobylinska via Scopus - Elsevier

Complex of synthetic 4-thiazolidinone derivatives with PEG-containing polymeric nanocarrier improve of biocompatibility and protects against toxicity in laboratory rats

Proceedings of the 2017 IEEE 7th International Conference on Nanomaterials: Applications and Properties, NAP 2017
2017 | Conference paper
DOI: 10.1109/NAP.2017.8190321
EID:

2-s2.0-85046286916
Contributors: Kobylinska, L.; Zimenkovsky, B.; Panchuk, R.; Skorohyd, N.; Boiko, N.; Stoika, R.; Zaichenko, A.
Source: Self-asserted source
Lesya Kobylinska via Scopus - Elsevier

Conjugation of anticancer drugs with novel PEG-containing nanocarrier provides circumvention of drug-resistance mechanisms in vitro and protects against general toxicity in vivo

Advanced Materials - TechConnect Briefs 2017
2017 | Conference paper
EID:

2-s2.0-85029374455
Contributors: Kobylinska, L.; Panchuk, R.; Skorohyd, N.; Senkiv, Y.; Heffeter, P.; Berger, W.; Boiko, N.; Mitina, N.; Zaichenko, A.; Lesyk, R. et al.
Source: Self-asserted source
Lesya Kobylinska via Scopus - Elsevier

Differential pro-apoptotic effects of synthetic 4-thiazolidinone derivative Les-3288, doxorubicin and temozolomide in human glioma U251 cells

Croatian Medical Journal
2017 | Journal article
DOI: 10.3325/cmj.2017.58.150
EID:

2-s2.0-85017559806
Contributors: Kobylinska, L.I.; Klyuchivska, O.Y.; Grytsyna, I.I.; Finiuk, N.; Panchuk, R.R.; Starykovych, M.O.; Lehka, L.; Lesyk, R.B.; Zimenkovsky, B.S.; Stoika, R.S.
Source: Self-asserted source
Lesya Kobylinska via Scopus - Elsevier

Indicators of oxidative and nitrosative stress and activity of enzymes of nitric oxide metabolism in rats treated with 4-thiazolidinone derivatives possessing antineoplastic activity

Ukrainian Biochemical Journal
2017 | Journal article
DOI: 10.15407/ubj89.05.077
EID:

2-s2.0-85032803380
Contributors: Kobylinska, L.I.; Panchuk, R.R.; Lesyk, R.B.; Zimenkovsky, B.S.; Stoika, R.S.
Source: Self-asserted source
Lesya Kobylinska via Scopus - Elsevier

The optoelectronic sensor creatinine and urea

Proceedings of SPIE - The International Society for Optical Engineering
2017 | Conference paper
DOI: 10.1117/12.2280990
EID:

2-s2.0-85029500057
Contributors: Vistak, M.V.; Dmytrakh, V.Y.; Diskovskyu, I.S.; Kobylinska, L.I.; Mikityuk, Z.M.; Petryshak, V.S.; Barylo, H.I.; Holyaka, R.L.; Amirgaliyev, Y.; Surtel, W. et al.
Source: Self-asserted source
Lesya Kobylinska via Scopus - Elsevier

4-Thiazolidinone derivative Les-3833 effectively inhibits viability of human melanoma cells through activating apoptotic mechanisms

Croatian Medical Journal
2017-04 | Journal article
Source: Self-asserted source
Lesya Kobylinska

Biochemical indicators of nephrotoxicity in blood serum of rats treated with novel 4-thiazolidinone derivatives or their complexes with polyethylene glycol-containing nanoscale polymeric carrier

Ukrainian Biochemical Journal
2016 | Journal article
DOI: 10.15407/ubj88.01.051
EID:

2-s2.0-84974577334
Contributors: Kobylinska, L.I.; Havrylyuk, D.Y.; Mitina, N.E.; Zaichenko, A.S.; Lesyk, R.B.; Zimenkovsky, B.S.; Stoika, R.S.
Source: Self-asserted source
Lesya Kobylinska via Scopus - Elsevier

Putative anticancer potential of novel 4-thiazolidinone derivatives: Cytotoxicity toward rat C6 glioma in vitro and correlation of general toxicity with the balance of free radical oxidation in rats

Croatian Medical Journal
2016 | Journal article
DOI: 10.3325/cmj.2016.57.151
EID:

2-s2.0-84971505153
Contributors: Kobylinska, L.I.; Boiko, N.M.; Panchuk, R.R.; Grytsyna, I.I.; Klyuchivska, O.Y.; Biletska, L.P.; Lesyk, R.B.; Zimenkovsky, B.S.; Stoika, R.S.
Source: Self-asserted source
Lesya Kobylinska via Scopus - Elsevier

Biochemical indicators of hepatotoxicity in blood serum of rats under the effect of novel 4-thiazolidinone derivatives and doxorubicin and their complexes with polyethyleneglycol-containing nanoscale polymeric carrier

Ukrainian Biochemical Journal
2015 | Journal article
EID:

2-s2.0-84940029286
Contributors: Kobylinska, L.I.; Havrylyuk, D.Y.; Ryabtseva, A.O.; Mitina, N.E.; Zaichenko, O.S.; Lesyk, R.B.; Zimenkovsky, B.S.; Stoika, R.S.
Source: Self-asserted source
Lesya Kobylinska via Scopus - Elsevier
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