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Employment (1)

Institute of Chemical Sciences: Košice, Slovak Republic, SK

scientist/RNDr., PhD. (Department of Organic Chemistry)
Employment
Source: Self-asserted source
Slavka Hamulakova

Works (19)

Design and synthesis of novel tacrine-indole hybrids as potential multitarget-directed ligands for the treatment of Alzheimer's disease

Future Medicinal Chemistry
2021 | Journal article
DOI: 10.4155/fmc-2020-0184
EID:

2-s2.0-85105221156

Part of ISSN: 17568927 17568919
Source: Self-asserted source
Slavka Hamulakova
grade
Preferred source (of 2)‎

Tacrine-coumarin derivatives as topoisomerase inhibitors with antitumor effects on a549 human lung carcinoma cancer cell lines

Molecules
2021 | Journal article
DOI: 10.3390/molecules26041133
EID:

2-s2.0-85102543205

Part of ISSN: 14203049
Source: Self-asserted source
Slavka Hamulakova
grade
Preferred source (of 2)‎

Synthesis of New Biscoumarin Derivatives, In Vitro Cholinesterase Inhibition, Molecular Modelling and Antiproliferative Effect in A549 Human Lung Carcinoma Cells

International Journal of Molecular Sciences
2021-04 | Journal article
DOI: 10.3390/ijms22083830
Source: Self-asserted source
Slavka Hamulakova
grade
Preferred source (of 3)‎

In vitro investigating of anticancer activity of new 7-MEOTA-tacrine heterodimers

Journal of Enzyme Inhibition and Medicinal Chemistry
2019 | Journal article
DOI: 10.1080/14756366.2019.1593159
EID:

2-s2.0-85063866757

Part of ISSN: 14756374 14756366
Source: Self-asserted source
Slavka Hamulakova
grade
Preferred source (of 2)‎

Proliferation inhibition of novel diphenylamine derivatives

Bioorganic Chemistry
2019 | Journal article
DOI: 10.1016/j.bioorg.2018.10.063
EID:

2-s2.0-85056661749

Part of ISSN: 10902120 00452068
Source: Self-asserted source
Slavka Hamulakova
grade
Preferred source (of 2)‎

Anti-cancer effect of tacrine-coumarin derivatives on diverse human and mouse cancer cell lines

Acta Chimica Slovenica
2018 | Journal article
DOI: 10.17344/acsi.2018.4519
EID:

2-s2.0-85061302115

Part of ISSN: 15803155 13180207
Source: Self-asserted source
Slavka Hamulakova
grade
Preferred source (of 2)‎

Lysozyme amyloid fibrillization in presence of tacrine/acridone-coumarin heterodimers

Colloids and Surfaces B: Biointerfaces
2018 | Journal article
DOI: 10.1016/j.colsurfb.2018.03.010
EID:

2-s2.0-85043606837

Part of ISSN: 18734367 09277765
Source: Self-asserted source
Slavka Hamulakova
grade
Preferred source (of 2)‎

Tacrine-coumarin and tacrine-7-chloroquinoline hybrids with thiourea linkers: Cholinesterase inhibition properties, kinetic study, molecular docking and permeability assay for blood-brain barrier

Current Alzheimer Research
2018 | Journal article
DOI: 10.2174/1567205015666180711110750
EID:

2-s2.0-85054409255

Part of ISSN: 18755828 15672050
Source: Self-asserted source
Slavka Hamulakova
grade
Preferred source (of 2)‎

Coumarin derivatives in pharmacotherapy of Alzheimer’s disease

Current Organic Chemistry
2017 | Journal article
DOI: 10.2174/1385272820666160601155411
EID:

2-s2.0-85013963746

Part of ISSN: 13852728
Source: Self-asserted source
Slavka Hamulakova
grade
Preferred source (of 2)‎

Synthesis, in vitro acetylcholinesterase inhibitory activity and molecular docking of new acridine-coumarin hybrids

International Journal of Biological Macromolecules
2017 | Journal article
DOI: 10.1016/j.ijbiomac.2017.06.006
EID:

2-s2.0-85020659867

Part of ISSN: 18790003 01418130
Source: Self-asserted source
Slavka Hamulakova
grade
Preferred source (of 2)‎

Targeting copper(II)-induced oxidative stress and the acetylcholinesterase system in Alzheimer's disease using multifunctional tacrine-coumarin hybrid molecules

Journal of Inorganic Biochemistry
2016 | Journal article
DOI: 10.1016/j.jinorgbio.2016.05.001
EID:

2-s2.0-84971623020

Part of ISSN: 18733344 01620134
Source: Self-asserted source
Slavka Hamulakova
grade
Preferred source (of 2)‎

Novel tacrine/acridine anticholinesterase inhibitors with piperazine and thiourea linkers

International Journal of Biological Macromolecules
2014 | Journal article
DOI: 10.1016/j.ijbiomac.2014.06.064
EID:

2-s2.0-84905271033

Part of ISSN: 18790003 01418130
Source: Self-asserted source
Slavka Hamulakova
grade
Preferred source (of 2)‎

Synthesis and biological evaluation of novel tacrine derivatives and tacrine-coumarin hybrids as cholinesterase inhibitors

Journal of Medicinal Chemistry
2014 | Journal article
DOI: 10.1021/jm5008648
EID:

2-s2.0-84906888262

Part of ISSN: 15204804 00222623
Source: Self-asserted source
Slavka Hamulakova
grade
Preferred source (of 2)‎

DNA binding acridine-thiazolidinone agents affecting intracellular glutathione

Bioorganic and Medicinal Chemistry
2012 | Journal article
DOI: 10.1016/j.bmc.2012.09.068
EID:

2-s2.0-84870057579

Part of ISSN: 09680896 14643391
Source: Self-asserted source
Slavka Hamulakova
grade
Preferred source (of 2)‎

Synthesis, design and biological evaluation of novel highly potent tacrine congeners for the treatment of Alzheimer's disease

European Journal of Medicinal Chemistry
2012 | Journal article
DOI: 10.1016/j.ejmech.2012.06.051
EID:

2-s2.0-84865770492

Part of ISSN: 02235234 17683254
Source: Self-asserted source
Slavka Hamulakova
grade
Preferred source (of 2)‎

Neuroactive multifunctional tacrine congeners with cholinesterase, anti-amyloid aggregation and neuroprotective properties

Pharmaceuticals
2011 | Journal article
DOI: 10.3390/ph4020382
EID:

2-s2.0-79952140384

Part of ISSN: 14248247
Source: Self-asserted source
Slavka Hamulakova
grade
Preferred source (of 2)‎

Synthesis, structure, and cholinergic effect of novel neuroprotective compounds bearing the tacrine pharmacophore

Heterocycles
2008 | Journal article
DOI: 10.3987/COM-08-S(N)83
EID:

2-s2.0-61349142543

Part of ISSN: 03855414
Source: Self-asserted source
Slavka Hamulakova
grade
Preferred source (of 2)‎

Configuration and E/Z interconversion mechanism of O(S)-allyl-S(O)-methyl- N-(acridin-9-yl)-iminothiocarbonate

Magnetic Resonance in Chemistry
2005 | Journal article
DOI: 10.1002/mrc.1564
EID:

2-s2.0-20544432162

Part of ISSN: 07491581
Source: Self-asserted source
Slavka Hamulakova
grade
Preferred source (of 2)‎

Synthesis of acetylcholinesterase inhibitors on the basis of 9-isothiocyanato-1,2,3,4-tetrahydroacridine: 2-[(1,2, 3,4-tetrahydroacridin-9-yl)imino]-3-substituted 1,3-thiazolidin-4-ones

Heterocycles
1998 | Journal article
DOI: 10.3987/COM-98-S16
EID:

2-s2.0-0032585391

Part of ISSN: 03855414
Source: Self-asserted source
Slavka Hamulakova
grade
Preferred source (of 2)‎
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