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SOD1 is a synthetic lethal target in PPM1D-mutant leukemia cells

2024-04-04 | Preprint
DOI: 10.7554/eLife.91611
Contributors: Linda Zhang; Joanne I. Hsu; Etienne D. Braekeleer; Chun-Wei Chen; Tajhal D. Patel; Alejandra G. Martell; Anna G. Guzman; Katharina Wohlan; Sarah M. Waldvogel; Hidetaka Urya et al.
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SOD1 is a synthetic lethal target in PPM1D-mutant leukemia cells

2024-04-04 | Preprint
DOI: 10.7554/eLife.91611.2
Contributors: Linda Zhang; Joanne I. Hsu; Etienne D. Braekeleer; Chun-Wei Chen; Tajhal D. Patel; Alejandra G. Martell; Anna G. Guzman; Katharina Wohlan; Sarah M. Waldvogel; Hidetaka Urya et al.
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TET2 modulates spatial relocalization of heterochromatin in aged hematopoietic stem and progenitor cells.

Nature aging
2023-10-26 | Journal article
DOI: 10.1038/s43587-023-00505-y
PMID: 37884767
Contributors: Hong T; Li J; Guo L; Maryn Cavalier; Wang T; Dou Y; DeLaFuente A; Fang S; Guzman A; Wohlan K et al.
Source: Self-asserted source
Katharina Wohlan

<i>SOD1</i>is a synthetic lethal target in<i>PPM1D</i>-mutant leukemia cells

2023-09-01 | Preprint | Author
DOI: 10.1101/2023.08.31.555634
Contributors: Linda Zhang; Joanne Hsu; Etienne De Braekeleer; Chun-Wei Chen; Tajhal D. Patel; Alejandra G. Martell; Anna G. Guzman; Katharina Wohlan; Sarah Waldvogel; Hidetaka Urya et al.
Source: Self-asserted source
Katharina Wohlan
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Data from SWI/SNF Blockade Disrupts PU.1-Directed Enhancer Programs in Normal Hematopoietic Cells and Acute Myeloid Leukemia

2023-04-04 | Preprint
DOI: 10.1158/0008-5472.c.6487384.v2
Contributors: Courtney Chambers; Katerina Cermakova; Yuen San Chan; Kristen Kurtz; Katharina Wohlan; Andrew Henry Lewis; Christiana Wang; Anh Pham; Milan Dejmek; Michal Sala et al.
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Supplementary Data from SWI/SNF Blockade Disrupts PU.1-Directed Enhancer Programs in Normal Hematopoietic Cells and Acute Myeloid Leukemia

2023-04-04 | Preprint
DOI: 10.1158/0008-5472.22549670.v1
Contributors: Courtney Chambers; Katerina Cermakova; Yuen San Chan; Kristen Kurtz; Katharina Wohlan; Andrew Henry Lewis; Christiana Wang; Anh Pham; Milan Dejmek; Michal Sala et al.
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Supplementary Data from SWI/SNF Blockade Disrupts PU.1-Directed Enhancer Programs in Normal Hematopoietic Cells and Acute Myeloid Leukemia

2023-04-04 | Preprint
DOI: 10.1158/0008-5472.22549670
Contributors: Courtney Chambers; Katerina Cermakova; Yuen San Chan; Kristen Kurtz; Katharina Wohlan; Andrew Henry Lewis; Christiana Wang; Anh Pham; Milan Dejmek; Michal Sala et al.
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Supplementary Dataset 1 from SWI/SNF Blockade Disrupts PU.1-Directed Enhancer Programs in Normal Hematopoietic Cells and Acute Myeloid Leukemia

2023-04-04 | Preprint
DOI: 10.1158/0008-5472.22549667.v1
Contributors: Courtney Chambers; Katerina Cermakova; Yuen San Chan; Kristen Kurtz; Katharina Wohlan; Andrew Henry Lewis; Christiana Wang; Anh Pham; Milan Dejmek; Michal Sala et al.
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Crossref

Supplementary Dataset 1 from SWI/SNF Blockade Disrupts PU.1-Directed Enhancer Programs in Normal Hematopoietic Cells and Acute Myeloid Leukemia

2023-04-04 | Preprint
DOI: 10.1158/0008-5472.22549667
Contributors: Courtney Chambers; Katerina Cermakova; Yuen San Chan; Kristen Kurtz; Katharina Wohlan; Andrew Henry Lewis; Christiana Wang; Anh Pham; Milan Dejmek; Michal Sala et al.
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Supplementary Dataset 2 from SWI/SNF Blockade Disrupts PU.1-Directed Enhancer Programs in Normal Hematopoietic Cells and Acute Myeloid Leukemia

2023-04-04 | Preprint
DOI: 10.1158/0008-5472.22549664.v1
Contributors: Courtney Chambers; Katerina Cermakova; Yuen San Chan; Kristen Kurtz; Katharina Wohlan; Andrew Henry Lewis; Christiana Wang; Anh Pham; Milan Dejmek; Michal Sala et al.
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Supplementary Dataset 2 from SWI/SNF Blockade Disrupts PU.1-Directed Enhancer Programs in Normal Hematopoietic Cells and Acute Myeloid Leukemia

2023-04-04 | Preprint
DOI: 10.1158/0008-5472.22549664
Contributors: Courtney Chambers; Katerina Cermakova; Yuen San Chan; Kristen Kurtz; Katharina Wohlan; Andrew Henry Lewis; Christiana Wang; Anh Pham; Milan Dejmek; Michal Sala et al.
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Supplementary Dataset 3 from SWI/SNF Blockade Disrupts PU.1-Directed Enhancer Programs in Normal Hematopoietic Cells and Acute Myeloid Leukemia

2023-04-04 | Preprint
DOI: 10.1158/0008-5472.22549661.v1
Contributors: Courtney Chambers; Katerina Cermakova; Yuen San Chan; Kristen Kurtz; Katharina Wohlan; Andrew Henry Lewis; Christiana Wang; Anh Pham; Milan Dejmek; Michal Sala et al.
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Crossref

Supplementary Dataset 3 from SWI/SNF Blockade Disrupts PU.1-Directed Enhancer Programs in Normal Hematopoietic Cells and Acute Myeloid Leukemia

2023-04-04 | Preprint
DOI: 10.1158/0008-5472.22549661
Contributors: Courtney Chambers; Katerina Cermakova; Yuen San Chan; Kristen Kurtz; Katharina Wohlan; Andrew Henry Lewis; Christiana Wang; Anh Pham; Milan Dejmek; Michal Sala et al.
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Supplementary Dataset 4 from SWI/SNF Blockade Disrupts PU.1-Directed Enhancer Programs in Normal Hematopoietic Cells and Acute Myeloid Leukemia

2023-04-04 | Preprint
DOI: 10.1158/0008-5472.22549658
Contributors: Courtney Chambers; Katerina Cermakova; Yuen San Chan; Kristen Kurtz; Katharina Wohlan; Andrew Henry Lewis; Christiana Wang; Anh Pham; Milan Dejmek; Michal Sala et al.
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Supplementary Dataset 4 from SWI/SNF Blockade Disrupts PU.1-Directed Enhancer Programs in Normal Hematopoietic Cells and Acute Myeloid Leukemia

2023-04-04 | Preprint
DOI: 10.1158/0008-5472.22549658.v1
Contributors: Courtney Chambers; Katerina Cermakova; Yuen San Chan; Kristen Kurtz; Katharina Wohlan; Andrew Henry Lewis; Christiana Wang; Anh Pham; Milan Dejmek; Michal Sala et al.
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SWI/SNF Blockade Disrupts PU.1-Directed Enhancer Programs in Normal Hematopoietic Cells and Acute Myeloid Leukemia.

Cancer research
2023-04-01 | Journal article | Author
DOI: 10.1158/0008-5472.can-22-2129
PMID: 36662812
PMC: PMC10071820
Contributors: Courtney Chambers; Katerina Cermakova; Yuen San Chan; Kristen Kurtz; Katharina Wohlan; Andrew Lewis; Christiana Wang; Anh Pham; Milan Dejmek; Michal Šála et al.
Source: Self-asserted source
Katharina Wohlan
grade
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Data from SWI/SNF Blockade Disrupts PU.1-Directed Enhancer Programs in Normal Hematopoietic Cells and Acute Myeloid Leukemia

2023-03-30 | Preprint
DOI: 10.1158/0008-5472.c.6487384
Contributors: Courtney Chambers; Katerina Cermakova; Yuen San Chan; Kristen Kurtz; Katharina Wohlan; Andrew Henry Lewis; Christiana Wang; Anh Pham; Milan Dejmek; Michal Sala et al.
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Crossref

Data from SWI/SNF Blockade Disrupts PU.1-Directed Enhancer Programs in Normal Hematopoietic Cells and Acute Myeloid Leukemia

2023-03-30 | Preprint
DOI: 10.1158/0008-5472.c.6487384.v1
Contributors: Courtney Chambers; Katerina Cermakova; Yuen San Chan; Kristen Kurtz; Katharina Wohlan; Andrew Henry Lewis; Christiana Wang; Anh Pham; Milan Dejmek; Michal Sala et al.
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Crossref

Supplementary Data from SWI/SNF Blockade Disrupts PU.1-Directed Enhancer Programs in Normal Hematopoietic Cells and Acute Myeloid Leukemia

2023-03-30 | Preprint
DOI: 10.1158/0008-5472.22361387
Contributors: Courtney Chambers; Katerina Cermakova; Yuen San Chan; Kristen Kurtz; Katharina Wohlan; Andrew Henry Lewis; Christiana Wang; Anh Pham; Milan Dejmek; Michal Sala et al.
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Crossref

Supplementary Data from SWI/SNF Blockade Disrupts PU.1-Directed Enhancer Programs in Normal Hematopoietic Cells and Acute Myeloid Leukemia

2023-03-30 | Preprint
DOI: 10.1158/0008-5472.22361387.v1
Contributors: Courtney Chambers; Katerina Cermakova; Yuen San Chan; Kristen Kurtz; Katharina Wohlan; Andrew Henry Lewis; Christiana Wang; Anh Pham; Milan Dejmek; Michal Sala et al.
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Crossref

Supplementary Dataset 1 from SWI/SNF Blockade Disrupts PU.1-Directed Enhancer Programs in Normal Hematopoietic Cells and Acute Myeloid Leukemia

2023-03-30 | Preprint
DOI: 10.1158/0008-5472.22361392.v1
Contributors: Courtney Chambers; Katerina Cermakova; Yuen San Chan; Kristen Kurtz; Katharina Wohlan; Andrew Henry Lewis; Christiana Wang; Anh Pham; Milan Dejmek; Michal Sala et al.
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Crossref

Supplementary Dataset 1 from SWI/SNF Blockade Disrupts PU.1-Directed Enhancer Programs in Normal Hematopoietic Cells and Acute Myeloid Leukemia

2023-03-30 | Preprint
DOI: 10.1158/0008-5472.22361392
Contributors: Courtney Chambers; Katerina Cermakova; Yuen San Chan; Kristen Kurtz; Katharina Wohlan; Andrew Henry Lewis; Christiana Wang; Anh Pham; Milan Dejmek; Michal Sala et al.
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Crossref

Supplementary Dataset 1 from SWI/SNF Blockade Disrupts PU.1-Directed Enhancer Programs in Normal Hematopoietic Cells and Acute Myeloid Leukemia

2023-03-30 | Preprint
DOI: 10.1158/0008-5472.22361381.v1
Contributors: Courtney Chambers; Katerina Cermakova; Yuen San Chan; Kristen Kurtz; Katharina Wohlan; Andrew Henry Lewis; Christiana Wang; Anh Pham; Milan Dejmek; Michal Sala et al.
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Crossref

Supplementary Dataset 1 from SWI/SNF Blockade Disrupts PU.1-Directed Enhancer Programs in Normal Hematopoietic Cells and Acute Myeloid Leukemia

2023-03-30 | Preprint
DOI: 10.1158/0008-5472.22361381
Contributors: Courtney Chambers; Katerina Cermakova; Yuen San Chan; Kristen Kurtz; Katharina Wohlan; Andrew Henry Lewis; Christiana Wang; Anh Pham; Milan Dejmek; Michal Sala et al.
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Supplementary Dataset 2 from SWI/SNF Blockade Disrupts PU.1-Directed Enhancer Programs in Normal Hematopoietic Cells and Acute Myeloid Leukemia

2023-03-30 | Preprint
DOI: 10.1158/0008-5472.22361372
Contributors: Courtney Chambers; Katerina Cermakova; Yuen San Chan; Kristen Kurtz; Katharina Wohlan; Andrew Henry Lewis; Christiana Wang; Anh Pham; Milan Dejmek; Michal Sala et al.
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Crossref

Supplementary Dataset 2 from SWI/SNF Blockade Disrupts PU.1-Directed Enhancer Programs in Normal Hematopoietic Cells and Acute Myeloid Leukemia

2023-03-30 | Preprint
DOI: 10.1158/0008-5472.22361383
Contributors: Courtney Chambers; Katerina Cermakova; Yuen San Chan; Kristen Kurtz; Katharina Wohlan; Andrew Henry Lewis; Christiana Wang; Anh Pham; Milan Dejmek; Michal Sala et al.
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Crossref

Supplementary Dataset 2 from SWI/SNF Blockade Disrupts PU.1-Directed Enhancer Programs in Normal Hematopoietic Cells and Acute Myeloid Leukemia

2023-03-30 | Preprint
DOI: 10.1158/0008-5472.22361383.v1
Contributors: Courtney Chambers; Katerina Cermakova; Yuen San Chan; Kristen Kurtz; Katharina Wohlan; Andrew Henry Lewis; Christiana Wang; Anh Pham; Milan Dejmek; Michal Sala et al.
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Crossref

Supplementary Dataset 2 from SWI/SNF Blockade Disrupts PU.1-Directed Enhancer Programs in Normal Hematopoietic Cells and Acute Myeloid Leukemia

2023-03-30 | Preprint
DOI: 10.1158/0008-5472.22361372.v1
Contributors: Courtney Chambers; Katerina Cermakova; Yuen San Chan; Kristen Kurtz; Katharina Wohlan; Andrew Henry Lewis; Christiana Wang; Anh Pham; Milan Dejmek; Michal Sala et al.
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Crossref

Supplementary Dataset 3 from SWI/SNF Blockade Disrupts PU.1-Directed Enhancer Programs in Normal Hematopoietic Cells and Acute Myeloid Leukemia

2023-03-30 | Preprint
DOI: 10.1158/0008-5472.22361380.v1
Contributors: Courtney Chambers; Katerina Cermakova; Yuen San Chan; Kristen Kurtz; Katharina Wohlan; Andrew Henry Lewis; Christiana Wang; Anh Pham; Milan Dejmek; Michal Sala et al.
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Crossref

Supplementary Dataset 3 from SWI/SNF Blockade Disrupts PU.1-Directed Enhancer Programs in Normal Hematopoietic Cells and Acute Myeloid Leukemia

2023-03-30 | Preprint
DOI: 10.1158/0008-5472.22361369.v1
Contributors: Courtney Chambers; Katerina Cermakova; Yuen San Chan; Kristen Kurtz; Katharina Wohlan; Andrew Henry Lewis; Christiana Wang; Anh Pham; Milan Dejmek; Michal Sala et al.
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Crossref

Supplementary Dataset 3 from SWI/SNF Blockade Disrupts PU.1-Directed Enhancer Programs in Normal Hematopoietic Cells and Acute Myeloid Leukemia

2023-03-30 | Preprint
DOI: 10.1158/0008-5472.22361380
Contributors: Courtney Chambers; Katerina Cermakova; Yuen San Chan; Kristen Kurtz; Katharina Wohlan; Andrew Henry Lewis; Christiana Wang; Anh Pham; Milan Dejmek; Michal Sala et al.
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Crossref

Supplementary Dataset 3 from SWI/SNF Blockade Disrupts PU.1-Directed Enhancer Programs in Normal Hematopoietic Cells and Acute Myeloid Leukemia

2023-03-30 | Preprint
DOI: 10.1158/0008-5472.22361369
Contributors: Courtney Chambers; Katerina Cermakova; Yuen San Chan; Kristen Kurtz; Katharina Wohlan; Andrew Henry Lewis; Christiana Wang; Anh Pham; Milan Dejmek; Michal Sala et al.
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Crossref

Supplementary Dataset 4 from SWI/SNF Blockade Disrupts PU.1-Directed Enhancer Programs in Normal Hematopoietic Cells and Acute Myeloid Leukemia

2023-03-30 | Preprint
DOI: 10.1158/0008-5472.22361366.v1
Contributors: Courtney Chambers; Katerina Cermakova; Yuen San Chan; Kristen Kurtz; Katharina Wohlan; Andrew Henry Lewis; Christiana Wang; Anh Pham; Milan Dejmek; Michal Sala et al.
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Crossref

Supplementary Dataset 4 from SWI/SNF Blockade Disrupts PU.1-Directed Enhancer Programs in Normal Hematopoietic Cells and Acute Myeloid Leukemia

2023-03-30 | Preprint
DOI: 10.1158/0008-5472.22361374.v1
Contributors: Courtney Chambers; Katerina Cermakova; Yuen San Chan; Kristen Kurtz; Katharina Wohlan; Andrew Henry Lewis; Christiana Wang; Anh Pham; Milan Dejmek; Michal Sala et al.
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Crossref

Supplementary Dataset 4 from SWI/SNF Blockade Disrupts PU.1-Directed Enhancer Programs in Normal Hematopoietic Cells and Acute Myeloid Leukemia

2023-03-30 | Preprint
DOI: 10.1158/0008-5472.22361374
Contributors: Courtney Chambers; Katerina Cermakova; Yuen San Chan; Kristen Kurtz; Katharina Wohlan; Andrew Henry Lewis; Christiana Wang; Anh Pham; Milan Dejmek; Michal Sala et al.
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Crossref

Supplementary Dataset 4 from SWI/SNF Blockade Disrupts PU.1-Directed Enhancer Programs in Normal Hematopoietic Cells and Acute Myeloid Leukemia

2023-03-30 | Preprint
DOI: 10.1158/0008-5472.22361366
Contributors: Courtney Chambers; Katerina Cermakova; Yuen San Chan; Kristen Kurtz; Katharina Wohlan; Andrew Henry Lewis; Christiana Wang; Anh Pham; Milan Dejmek; Michal Sala et al.
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Murine Models of Acute Myeloid Leukemia.

Frontiers in oncology
2022-06-08 | Journal article
DOI: 10.3389/fonc.2022.854973
PMID: 35756660
PMC: PMC9214208
Contributors: Kurtz KJ; Conneely SE; O'Keefe M; Wohlan K; Rau RE
Source: Self-asserted source
Katharina Wohlan

Chemotherapy-Free Targeted Anti-BCR-ABL+ Acute Lymphoblastic Leukemia Therapy May Benefit the Heart.

Cancers
2022-02-15 | Journal article
DOI: 10.3390/cancers14040983
PMID: 35205731
PMC: PMC8870618
Contributors: Kirchhoff H; Melanie Ricke-Hoch; Wohlan K; Pietzsch S; Ümran Karsli; Erschow S; Robert Zweigerdt; Arnold Ganser; Eder M; Scherr M et al.
Source: Self-asserted source
Katharina Wohlan

Anthracycline-free tumor elimination in mice leads to functional and molecular cardiac recovery from cancer-induced alterations in contrast to long-lasting doxorubicin treatment effects.

Basic research in cardiology
2021-10-20 | Journal article
DOI: 10.1007/s00395-021-00902-7
PMID: 34669013
PMC: PMC8528750
Contributors: Pietzsch S; Wohlan K; Thackeray JT; Heimerl M; Schuchardt S; Scherr M; Melanie Ricke-Hoch; Hilfiker-Kleiner D
Source: Self-asserted source
Katharina Wohlan

Stable depletion of RUNX1-ETO in Kasumi-1 cells induces expression and enhanced proteolytic activity of Cathepsin G and Neutrophil Elastase.

PloS one
2019-12-11 | Journal article
DOI: 10.1371/journal.pone.0225977
PMID: 31826021
PMC: PMC6905530
Contributors: Schoenherr C; Wohlan K; Dallmann I; Pich A; Hegermann J; Arnold Ganser; Hilfiker-Kleiner D; Heidenreich O; Michaela Scherr; Eder M
Source: Self-asserted source
Katharina Wohlan

Optimized induction of mitochondrial apoptosis for chemotherapy-free treatment of BCR-ABL+acute lymphoblastic leukemia.

Leukemia
2018-12-13 | Journal article
DOI: 10.1038/s41375-018-0315-6
PMID: 30546081
PMC: PMC6756054
Contributors: Scherr M; Kirchhoff H; Battmer K; Wohlan K; Lee CW; Ricke-Hoch M; Erschow S; Law E; Kloos A; Heuser M et al.
Source: Self-asserted source
Katharina Wohlan

Suppression of RUNX1/ETO oncogenic activity by a small molecule inhibitor of tetramerization.

Haematologica
2017-02-02 | Journal article
DOI: 10.3324/haematol.2016.161570
PMID: 28154087
PMC: PMC5685283
Contributors: Schanda J; Lee CW; Wohlan K; Müller-Kuller U; Kunkel H; Coco IQ; Stein S; Metz A; Koch J; Lausen J et al.
Source: Self-asserted source
Katharina Wohlan

miR-181a Expression in Donor T Cells Modulates Graft-versus-Host Disease after Allogeneic Bone Marrow Transplantation.

Journal of immunology (Baltimore, Md. : 1950)
2016-03-23 | Journal article
DOI: 10.4049/jimmunol.1502152
PMID: 27009493
Contributors: Lee CW; Wohlan K; Dallmann I; Reinhold Forster; Ganser A; Andreas Krueger; Scherr M; Eder M; Christian Koenecke
Source: Self-asserted source
Katharina Wohlan

Pyknotic cell death induced by Clostridium difficile TcdB: chromatin condensation and nuclear blister are induced independently of the glucosyltransferase activity.

Cellular microbiology
2014-08-04 | Journal article
DOI: 10.1111/cmi.12317
PMID: 24898616
Contributors: Wohlan K; Goy S; Olling A; Srivaratharajan S; Tatge H; Genth H; Gerhard R
Source: Self-asserted source
Katharina Wohlan
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