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Scopus Author ID: 6508222325
ResearcherID: B-9799-2009
ResearcherID: E-7171-2014

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United States

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Employment (1)

University of Washington: Seattle, WA, US

2012-09-01 to present (Department of Biology)
Employment
Source: Self-asserted source
Alexander Paredez

Education and qualifications (3)

Stanford University: Stanford, CA, US

2006-09 | PhD (Biological Sciences)
Education
Source: Self-asserted source
Alexander Paredez

University of California San Diego: La Jolla, CA, US

1999-06 | M.S. (Biology)
Education
Source: Self-asserted source
Alexander Paredez

University of California San Diego: La Jolla, CA, US

1998-06 | BS
Education
Source: Self-asserted source
Alexander Paredez

Funding (2)

Rac: a critical regulator of the cytoskeleton and membrane trafficking in Giardia

2015-02-01 to 2020-01-31 | Grant
National Institute of Allergy and Infectious Diseases (Bethesda, US)
URL: https://grants.uberresearch.com/100000060/R01AI110708/Rac-a-critical-regulator-of-the-cytoskeleton-and-membrane-trafficking-in-Giardia
GRANT_NUMBER: 5R01AI110708-02
Source: Self-asserted source
Alexander Paredez via DimensionsWizard

Minority PostDoctoral Fellowship FY2007

2007-07-01 to 2010-06-30 | Grant
National Science Foundation - Directorate for Biological Sciences (Arlington, US)
URL: https://grants.uberresearch.com/100000076/0705351/Minority-PostDoctoral-Fellowship-FY2007
GRANT_NUMBER: 0705351
Source: Self-asserted source
Alexander Paredez via DimensionsWizard

Works (30)

Unraveling the role of cAMP signaling in Giardia : insights into PKA-mediated regulation of encystation and subcellular interactions

mSphere
2024-11-21 | Journal article
DOI: 10.1128/msphere.00723-24
Contributors: Han-Wei Shih; Germain C. M. Alas; Alexander R. Paredez; Katherine S. Ralston
Source: check_circle
Crossref

Unraveling the Role of cAMP Signaling inGiardia: Insights into PKA-Mediated Regulation of Encystation and Subcellular Interactions

2024-04-29 | Preprint
DOI: 10.1101/2024.04.26.591389
Contributors: Han-Wei Shih; Germain C.M. Alas; Alexander R. Paredez
Source: check_circle
Crossref

Encystation stimuli sensing is mediated by adenylate cyclase AC2-dependent cAMP signaling in Giardia

Nature Communications
2023-11-09 | Journal article
DOI: 10.1038/s41467-023-43028-1
Contributors: Han-Wei Shih; Germain C. M. Alas; Alexander R. Paredez
Source: check_circle
Crossref

Encystation stimuli sensing mediated by adenylate cyclase AC2-dependent cAMP signaling in Giardia

2023-04-25 | Preprint
DOI: 10.21203/rs.3.rs-2818450/v1
Contributors: Alexander Paredez; Han-Wei Shih; Germain Alas
Source: check_circle
Crossref

A cell-cycle–dependent GARP-like transcriptional repressor regulates the initiation of differentiation in Giardia lamblia

Proceedings of the National Academy of Sciences
2022-05-31 | Journal article
DOI: 10.1073/pnas.2204402119
Contributors: Han-Wei Shih; Germain C. M. Alas; Alexander R. Paredez
Source: check_circle
Crossref

Disc and Actin Associated Protein 1 influences attachment in the intestinal parasite Giardia lamblia

PLOS Pathogens
2022-03-25 | Journal article
DOI: 10.1371/journal.ppat.1010433
Contributors: Melissa C. Steele-Ogus; Carmen Faso; Ava M. Obenaus; Nathan J. Sniadecki; Alexander R. Paredez
Source: check_circle
Crossref

Identification of Actin Filament-Associated Proteins in Giardia lamblia

Microbiology Spectrum
2021-09-03 | Journal article
DOI: 10.1128/Spectrum.00558-21
Contributors: Melissa C. Steele-Ogus; Richard S. Johnson; Michael J. MacCoss; Alexander R. Paredez; Christina A. Cuomo
Source: check_circle
Crossref

A cell cycle-dependent GARP-like transcriptional repressor regulates the initiation of differentiation in Giardia lamblia

2021-05-28 | Preprint
DOI: 10.1101/2021.05.27.446072
Contributors: Han-Wei Shih; Germain C.M. Alas; Alexander R. Paredez
Source: check_circle
Crossref

Identification of Actin Filament Interactors in Giardia lamblia

2021-05-20 | Other
DOI: 10.1101/2021.05.19.444898
Contributors: Melissa C. Steele-Ogus; Richard Johnson; Michael MacCoss; Alexander R. Paredez
Source: check_circle
Crossref

A Curious Case for Development of Kinase Inhibitors as Antigiardiasis Treatments Using Advanced Drug Techniques

ACS Infectious Diseases
2021-05-14 | Journal article
DOI: 10.1021/acsinfecdis.0c00919
Contributors: Samantha A. Michaels; Kelly M. Hennessey; Neal Paragas; Alexander R. Paredez; Kayode K. Ojo
Source: check_circle
Crossref

Stage-specific, morphological and molecular markers of encystation inGiardia lamblia

2021-02-02 | Preprint
DOI: 10.1101/2021.02.01.429238
Contributors: Elizabeth B. Thomas; Renaldo Sutanto; Richard S. Johnson; Han-Wei Shih; Jana Krtková; Michael J. MacCoss; Alexander R. Paredez
Source: check_circle
Crossref

Nek8445, a protein kinase required for microtubule regulation and cytokinesis in Giardia lamblia

2019-07-30 | Other
DOI: 10.1101/719005
Contributors: Kelly M. Hennessey; Germain C.M. Alas; Ilse Rogiers; Renyu Li; Ethan A. Merritt; Alexander R. Paredez
Source: check_circle
Crossref

Hybrid Structured Illumination Expansion Microscopy Reveals Microbial Cytoskeleton Organization

ACS Nano
2017-12-26 | Journal article
DOI: 10.1021/acsnano.7b07200
Contributors: Aaron R. Halpern; Germain C. M. Alas; Tyler J. Chozinski; Alexander R. Paredez; Joshua C. Vaughan
Source: check_circle
Crossref

14-3-3 Regulates Actin Filament Formation in the Deep-Branching Eukaryote Giardia lamblia

mSphere
2017-10-25 | Journal article
DOI: 10.1128/mSphere.00248-17
Contributors: Jana Krtková; Jennifer Xu; Marco Lalle; Melissa Steele-Ogus; Germain C. M. Alas; David Sept; Alexander R. Paredez; Ira J. Blader
Source: check_circle
Crossref

Myosin-independent cytokinesis in Giardia utilizes flagella to coordinate force generation and direct membrane trafficking

Proceedings of the National Academy of Sciences
2017-07-18 | Journal article
DOI: 10.1073/pnas.1705096114
Contributors: William R. Hardin; Renyu Li; Jason Xu; Andrew M. Shelton; Germain C. M. Alas; Vladimir N. Minin; Alexander R. Paredez
Source: check_circle
Crossref

14-3-3 Negatively Regulates Actin Filament Formation in the Deep Branching EukaryoteGiardia lamblia

2017-05-26 | Preprint
DOI: 10.1101/142505
Contributors: Jana Krtková; Jennifer Xu; Marco Lalle; Melissa Steele-Ogus; Germain C. M. Alas; David Sept; Alexander R. Paredez
Source: check_circle
Crossref

Identification and Validation of Small-Gatekeeper Kinases as Drug Targets in Giardia lamblia

PLOS Neglected Tropical Diseases
2016-11-02 | Journal article
DOI: 10.1371/journal.pntd.0005107
Contributors: Kelly M. Hennessey; Tess R. Smith; Jennifer W. Xu; Germain C. M. Alas; Kayode K. Ojo; Ethan A. Merritt; Alexander R. Paredez; Timothy G. Geary
Source: Self-asserted source
Alexander Paredez via Crossref Metadata Search
grade
Preferred source (of 2)‎

Rac RegulatesGiardia lambliaEncystation by Coordinating Cyst Wall Protein Trafficking and Secretion

mBio
2016-08 | Journal article
DOI: 10.1128/mbio.01003-16
Contributors: Jana Krtková; Elizabeth B. Thomas; Germain C. M. Alas; Elisabeth M. Schraner; Habib R. Behjatnia; Adrian B. Hehl; Alexander R. Paredez
Source: Self-asserted source
Alexander Paredez via Crossref Metadata Search

Identification of Obscure yet Conserved Actin-Associated Proteins in Giardia lamblia

Eukaryotic Cell
2014 | Journal article
DOI: 10.1128/EC.00041-14
WOSUID:

WOS:000337350000009
Contributors: Paredez, Alexander R.; Nayeri, Arash; Xu, Jennifer W.; Krtkova, Jana; Cande, W. Zacheus
Source: Self-asserted source
Alexander Paredez via ResearcherID

Alternative cytoskeletal landscapes: cytoskeletal novelty and evolution in basal excavate protists

Current Opinion in Cell Biology
2013 | Journal article
DOI:

10.1016/j.ceb.2012.11.005
Source: Self-asserted source
Alexander Paredez via Scopus - Elsevier

An actin cytoskeleton with evolutionarily conserved functions in the absence of canonical actin-binding proteins

Proceedings of the National Academy of Sciences of the United States of America
2011 | Journal article
DOI:

10.1073/pnas.1018593108

Part of ISSN:

0027-8424
Contributors: Paredez, Alexander R.; Assaf, Zoe June; Sept, David; Timofejeva, Ljudmilla; Dawson, Scott C.; Wang, Chung-Ju Rachel; Cande, W. Z.
Source: Self-asserted source
Alexander Paredez via ResearcherID

The Genome of Naegleria gruberi Illuminates Early Eukaryotic Versatility

Cell
2010 | Journal article
DOI:

10.1016/j.cell.2010.01.032
Source: Self-asserted source
Alexander Paredez via Scopus - Elsevier

Arabidopsis cortical microtubules position cellulose synthase delivery to the plasma membrane and interact with cellulose synthase trafficking compartments

Nature Cell Biology
2009 | Journal article
DOI:

10.1038/ncb1886
Source: Self-asserted source
Alexander Paredez via Scopus - Elsevier

Organization of cellulose synthase trafficking and motility in the plasma membrane by the cortical microtubule array

Microscopy and Microanalysis
2009 | Journal article
DOI:

10.1017/S1431927609099358
Source: Self-asserted source
Alexander Paredez via Scopus - Elsevier

Genetic evidence that cellulose synthase activity influences microtubule cortical array organization

Plant Physiology
2008 | Journal article
DOI:

10.1104/pp.108.120196
Source: Self-asserted source
Alexander Paredez via Scopus - Elsevier

Prefoldin 6 is required for normal microtubule dynamics and organization in Arabidopsis

Proceedings of the National Academy of Sciences of the United States of America
2008 | Journal article
DOI:

10.1073/pnas.0808652105
Source: Self-asserted source
Alexander Paredez via Scopus - Elsevier

Genetic evidence for three unique components in primary cell-wall cellulose synthase complexes in Arabidopsis

Proceedings of the National Academy of Sciences of the United States of America
2007 | Journal article
DOI:

10.1073/pnas.0706592104
Source: Self-asserted source
Alexander Paredez via Scopus - Elsevier

Visualization of cellulose synthase demonstrates functional association with microtubules

Science
2006 | Journal article
DOI:

10.1126/science.1126551
Source: Self-asserted source
Alexander Paredez via Scopus - Elsevier

Toward a systems approach to understanding plant cell walls

Science
2004 | Journal article
DOI:

10.1126/science.1102765
Source: Self-asserted source
Alexander Paredez via Scopus - Elsevier

The coronin-like protein POD-1 is required for anterior-posterior axis formation and cellular architecture in the nematode Caenorhabditis elegans

Genes and Development
1999 | Journal article
DOI:

10.1101/gad.13.21.2838
Source: Self-asserted source
Alexander Paredez via Scopus - Elsevier

Peer review (3 reviews for 1 publication/grant)

Review activity for PLOS pathogens : (3)
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