Personal information

Countries

United States

Biography

B. S., Biochemistry and Molecular Biology with Honors in Biochemistry and Molecular Biology, The Pennsylvania State University, 2010
Ph. D. in Biochemistry, Molecular, and Cell Biology, Minor in Microbiology, Cornell University, 2010-May 2016

Activities

Collapse all

Works (15)

Golgi stress induces SIRT2 to counteract Shigella infection via defatty-acylation

Nature Communications
2022-08-02 | Journal article | Author
DOI: 10.1038/s41467-022-32227-x
Part of ISSN: 2041-1723
Contributors: Miao Wang; Yugang Zhang; Garrison P. Komaniecki; Xuan Lu; Ji Cao; Mingming Zhang; Tao Yu; Dan Hou; Nicole A. Spiegelman; Ming Yang et al.
Source: Self-asserted source
Ian Price

Long-chain fatty acyl coenzyme A inhibits NME1/2 and regulates cancer metastasis

Proceedings of the National Academy of Sciences
2022-03-15 | Journal article
DOI: 10.1073/pnas.2117013119
Contributors: Shuai Zhang; Ornella D. Nelson; Ian R. Price; Chengliang Zhu; Xuan Lu; Irma R. Fernandez; Robert S. Weiss; Hening Lin
Source: check_circle
Crossref

Binding Affinity Determines Substrate Specificity and Enables Discovery of Substrates for N-Myristoyltransferases

ACS Catalysis
2021-12-17 | Journal article | Author
DOI: 10.1021/acscatal.1c03330
Part of ISSN: 2155-5435
Part of ISSN: 2155-5435
Contributors: Dan Su; Tatsiana Kosciuk; Min Yang; Ian Price; Hening Lin
Source: Self-asserted source
Ian Price
grade
Preferred source (of 2)‎

Simultaneous Inhibition of SIRT2 Deacetylase and Defatty-Acylase Activities via a PROTAC Strategy

ACS Medicinal Chemistry Letters
2020-11-12 | Journal article | Author
DOI: 10.1021/acsmedchemlett.0c00423
Part of ISSN: 1948-5875
Part of ISSN: 1948-5875
Contributors: Jun Young Hong; Hui Jing; Ian Price; Ji Cao; Jessica Jingyi Bai; Hening Lin
Source: Self-asserted source
Ian Price
grade
Preferred source (of 2)‎

NMT1 and NMT2 are lysine myristoyltransferases regulating the ARF6 GTPase cycle

Nature Communications
2020-02-26 | Journal article
DOI: 10.1038/s41467-020-14893-x
Contributors: Tatsiana Kosciuk; Ian R. Price; Xiaoyu Zhang; Chengliang Zhu; Kayla N. Johnson; Shuai Zhang; Steve L. Halaby; Garrison P. Komaniecki; Min Yang; Caroline J. DeHart et al.
Source: check_circle
Crossref

ATP/ADP modulates gp16–pRNA conformational change in the Phi29 DNA packaging motor

Nucleic Acids Research
2019-10-10 | Journal article
DOI: 10.1093/nar/gkz692
Contributors: Rujie Cai; Ian R Price; Fang Ding; Feifei Wu; Ting Chen; Yunlong Zhang; Guangfeng Liu; Paul J Jardine; Changrui Lu; Ailong Ke
Source: check_circle
Crossref

Local-to-global signal transduction at the core of a Mn2+ sensing riboswitch

Nature Communications
2019-09-20 | Journal article
DOI: 10.1038/s41467-019-12230-5
Contributors: Krishna C. Suddala; Ian R. Price; Shiba S. Dandpat; Michal Janeček; Petra Kührová; Jiří Šponer; Pavel Banáš; Ailong Ke; Nils G. Walter
Source: check_circle
Crossref

A Glycoconjugated SIRT2 Inhibitor with Aqueous Solubility Allows Structure-Based Design of SIRT2 Inhibitors

ACS Chemical Biology
2019-08-16 | Journal article
DOI: 10.1021/acschembio.9b00384
Part of ISSN: 1554-8929
Part of ISSN: 1554-8937
Contributors: Jun Young Hong; Ian Robert Price; Jessica Jingyi Bai; Hening Lin
Source: Self-asserted source
Ian Price

Novel Lysine-Based Thioureas as Mechanism-Based Inhibitors of Sirtuin 2 (SIRT2) with Anticancer Activity in a Colorectal Cancer Murine Model

Journal of Medicinal Chemistry
2019-04-25 | Journal article
DOI: 10.1021/acs.jmedchem.9b00191
Part of ISSN: 0022-2623
Part of ISSN: 1520-4804
Contributors: Ali Farooqi; Jun Young Hong; Ji Cao; Xuan Lu; Ian Robert Price; Qingjie Zhao; Tatsiana Kosciuk; Min Yang; Jessica Jingyi Bai; Hening Lin
Source: Self-asserted source
Ian Price

A Small‐Molecule SIRT2 Inhibitor That Promotes K‐Ras4a Lysine Fatty‐Acylation

ChemMedChem
2019-04-03 | Journal article
DOI: 10.1002/cmdc.201800715
Contributors: Nicole A. Spiegelman; Jun Young Hong; Jing Hu; Hui Jing; Miao Wang; Ian R. Price; Ji Cao; Min Yang; Xiaoyu Zhang; Hening Lin
Source: check_circle
Crossref

Direct Comparison of SIRT2 Inhibitors: Potency, Specificity, Activity‐Dependent Inhibition, and On‐Target Anticancer Activities

ChemMedChem
2018-09-19 | Journal article
DOI: 10.1002/cmdc.201800391
Part of ISSN: 1860-7179
Part of ISSN: 1860-7187
Contributors: Nicole A. Spiegelman; Ian R. Price; Hui Jing; Miao Wang; Min Yang; Ji Cao; Jun Young Hong; Xiaoyu Zhang; Pornpun Aramsangtienchai; Sushabhan Sadhukhan et al.
Source: Self-asserted source
Ian Price

Functional characterization and crystal structure of thermostable amylase from Thermotoga petrophila , reveals high thermostability and an unusual form of dimerization

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics
2017-10 | Journal article
DOI: 10.1016/j.bbapap.2017.06.015
Part of ISSN: 1570-9639
Contributors: Uzma Hameed; Ian Price; Ikram-Ul-Haq; Ailong Ke; David B. Wilson; Osman Mirza
Source: Self-asserted source
Ian Price

Structural basis for guanidine sensing by the <i>ykkC</i> family of riboswitches

RNA
2017-04 | Journal article
DOI: 10.1261/rna.060186.116
Part of ISSN: 1355-8382
Part of ISSN: 1469-9001
Contributors: Robert A. Battaglia; Ian R. Price; Ailong Ke
Source: Self-asserted source
Ian Price

Mn2+-Sensing Mechanisms of yybP-ykoY Orphan Riboswitches

Molecular Cell
2015-03 | Journal article
DOI: 10.1016/j.molcel.2015.02.016
Part of ISSN: 1097-2765
Contributors: Ian R. Price; Ahmed Gaballa; Fang Ding; John D. Helmann; Ailong Ke
Source: Self-asserted source
Ian Price

Common themes and differences in SAM recognition among SAM riboswitches

Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms
2014-10 | Journal article | Author
DOI: 10.1016/j.bbagrm.2014.05.013
Part of ISSN: 1874-9399
Contributors: Ian Price; Jason C. Grigg; Ailong Ke
Source: Self-asserted source
Ian Price
How many people are using ORCID?