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Scopus Author ID: 23492624000

Keywords

spinal cord injury, plasticity, glycoscience

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Employment (5)

University of Leeds: Leeds, GB

2019-06 to present | Associate Professor (School of Biomedical Sciences)
Employment
Source: Self-asserted source
Jessica CF Kwok

Institute of Experimental Medicine: Prague, CZ

2017-01-01 to 2022-12-31 | Visiting scientist
Employment
Source: Self-asserted source
Jessica CF Kwok

University of Leeds: Leeds, GB

2016 to 2019-05 | Group leader/University Academic Fellow (School of Biomedical Sciences)
Employment
Source: Self-asserted source
Jessica CF Kwok

University of Cambridge: Cambridge, Cambridgeshire, GB

2005 to 2015 (John van Geest Centre for Brain Repair)
Employment
Source: Self-asserted source
Jessica CF Kwok

The University of Hong Kong: Hong Kong, HK, HK

2004-12-05 to 2005-05-31 | Research Assistant (Department of Biochemistry)
Employment
Source: Self-asserted source
Jessica CF Kwok

Education and qualifications (1)

The University of Hong Kong: Hong Kong, HK, HK

2000-09-22 to 2004-12-05 | PhD (Department of Biochemistry)
Education
Source: Self-asserted source
Jessica CF Kwok

Professional activities (2)

European Society for Neurochemistry: UK, GB

2023-08 to present | Council member
Service
Source: Self-asserted source
Jessica CF Kwok

International Neurotrauma Society: N/A, US

2019-06 to present | International Advisory Committee
Service
Source: Self-asserted source
Jessica CF Kwok

Works (50 of 61)

Items per page:
Page 1 of 2

Differential expression of genes in the RhoA/ROCK pathway in the hippocampus and cortex following intermittent hypoxia and high-intensity interval training

Journal of Neurophysiology
2024-08-01 | Journal article
DOI: 10.1152/jn.00422.2023
Contributors: Natalie E. Doody; Nicole J. Smith; Elizabeth C. Akam; Graham N. Askew; Jessica C. F. Kwok; Ronaldo M. Ichiyama
Source: check_circle
Crossref

Revealing the unbinding mechanics of hyaluronan·receptor interactions on live cells

Proteoglycan Research
2024-07 | Journal article
DOI: 10.1002/pgr2.70002
Contributors: Itzel Garcia‐Monge; Ashleigh Goodenough; Cihan Civan Cıvaş; Jessica C. F. Kwok; Ralf P. Richter
Source: check_circle
Crossref

Hyperactive PI3Kinase delta enables long distance regeneration of the rat corticospinal tract

2023-11-01 | Preprint
DOI: 10.1101/2023.10.27.564182
Contributors: Kristyna Karova; Zuzana Polcanova; Stepanka Suchankova; Lydia Knight; Bart Nieuwenhuis; Radovan Holota; Vit Herynek; Lucia Machova Urdzikova; Rostislav Turecek; Jessica C.F. Kwok et al.
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Crossref

4-Methylumbeliferone Treatment at a Dose of 1.2 g/kg/Day Is Safe for Long-Term Usage in Rats

International Journal of Molecular Sciences
2023-02-14 | Journal article
DOI: 10.3390/ijms24043799
Contributors: Kateřina Štěpánková; Dana Mareková; Kristýna Kubášová; Radek Sedláček; Karolína Turnovcová; Irena Vacková; Šárka Kubinová; Pavol Makovický; Michaela Petrovičová; Jessica C. F. Kwok et al.
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4-methylumbelliferone enhances neuroplasticity in the central nervous system: potential oral treatment for SCI

2023-01-23 | Preprint
DOI: 10.1101/2023.01.23.525137
Contributors: Sîan F. Irvine; Sylvain Gigout; Kateřina Štěpánková; Noelia Martinez Varea; Lucia Machová Urdzíková; Pavla Jendelová; Jessica C. F. Kwok
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Crossref

Perineuronal nets affect memory and learning after synapse withdrawal

Translational Psychiatry
2022-11-15 | Journal article
DOI: 10.1038/s41398-022-02226-z
Contributors: Jiri Ruzicka; Marketa Dalecka; Kristyna Safrankova; Diego Peretti; Pavla Jendelova; Jessica C. F. Kwok; James W. Fawcett
Source: check_circle
Crossref

The extracellular matrix and perineuronal nets in memory

Molecular Psychiatry
2022-08 | Journal article
DOI: 10.1038/s41380-022-01634-3
Contributors: James W. Fawcett; Marianne Fyhn; Pavla Jendelova; Jessica C. F. Kwok; Jiri Ruzicka; Barbara A. Sorg
Source: check_circle
Crossref

An in vitro neuronal model replicating the in vivo maturation and heterogeneity of perineuronal nets

2022-01-23 | Preprint
DOI: 10.1101/2022.01.22.477344
Contributors: S Dickens; A Goodenough; JCF Kwok
Source: check_circle
Crossref

Perineuronal nets affect memory and learning after synapse withdrawal

bioRvix
2021-04-14 | Other
DOI: 10.1101/2021.04.13.439599
Source: Self-asserted source
Jessica CF Kwok
grade
Preferred source (of 2)‎

Oxygen transport kinetics underpin rapid and robust diaphragm recovery following chronic spinal cord injury

The Journal of Physiology
2021-02 | Journal article
DOI: 10.1113/JP280684
Contributors: Philippa M. Warren; Roger W. P. Kissane; Stuart Egginton; Jessica C. F. Kwok; Graham N. Askew
Source: check_circle
Crossref

Systemic α-synuclein injection triggers selective neuronal pathology as seen in patients with Parkinson’s disease

Molecular Psychiatry
2021-02-22 | Journal article
DOI: 10.1038/s41380-019-0608-9
Contributors: Wei-Li Kuan; Katherine Stott; Xiaoling He; Tobias C. Wood; Sujeong Yang; Jessica C. F. Kwok; Katie Hall; Yanyan Zhao; Ole Tietz; Franklin I. Aigbirhio et al.
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Crossref

Transplantation of Neural Precursors Derived from Induced Pluripotent Cells Preserve Perineuronal Nets and Stimulate Neural Plasticity in ALS Rats

International Journal of Molecular Sciences
2020-12-16 | Journal article
DOI: 10.3390/ijms21249593
Contributors: Serhiy Forostyak; Oksana Forostyak; Jessica C. F. Kwok; Nataliya Romanyuk; Monika Rehorova; Jan Kriska; Govindan Dayanithi; Ruma Raha-Chowdhury; Pavla Jendelova; Miroslava Anderova et al.
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New Model of Ventral Spinal Cord Lesion Induced by Balloon Compression in Rats

Biomedicines
2020-11-05 | Journal article
DOI: 10.3390/biomedicines8110477
Contributors: Petr Krupa; Katerina Stepankova; Jessica CF. Kwok; James W. Fawcett; Veronika Cimermanova; Pavla Jendelova; Lucia Machova Urdzikova
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Secretion of a mammalian chondroitinase ABC aids glial integration at PNS/CNS boundaries

Scientific Reports
2020-07-09 | Journal article
DOI: 10.1038/s41598-020-67526-0
Contributors: Philippa M. Warren; Melissa R. Andrews; Marc Smith; Katalin Bartus; Elizabeth J. Bradbury; Joost Verhaagen; James W. Fawcett; Jessica C. F. Kwok
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Crossref

Immunochemical analysis of the integrin expression in retinal pigment epithelial cells

2020-06-27 | Preprint
DOI: 10.1101/2020.06.26.133553
Contributors: Janosch P Heller; Tristan G Heintz; Jessica CF Kwok; Keith R Martin; James W Fawcett
Source: check_circle
Crossref

Neuronal Pentraxin 2 Binds PNNs and Enhances PNN Formation

Neural Plasticity
2019-10-20 | Journal article
DOI: 10.1155/2019/6804575
Contributors: Heleen M. Van’t Spijker; Dáire Rowlands; Jean Rossier; Barbara Haenzi; James W. Fawcett; Jessica C. F. Kwok
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Crossref

The potential of memory enhancement through modulation of perineuronal nets

British Journal of Pharmacology
2019-09 | Journal article
DOI: 10.1111/bph.14672
Contributors: James A. Duncan; Richard Foster; Jessica C.F. Kwok
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Crossref

Glycosaminoglycans in extracellular matrix organisation: are concepts from soft matter physics key to understanding the formation of perineuronal nets?

Current Opinion in Structural Biology
2018-06 | Journal article
DOI: 10.1016/j.sbi.2017.12.002
Contributors: Ralf P Richter; Natalia S Baranova; Anthony J Day; Jessica CF Kwok
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Crossref

Perineuronal Nets in Spinal Motoneurones: Chondroitin Sulphate Proteoglycan around Alpha Motoneurones

International Journal of Molecular Sciences
2018-04 | Journal article
DOI: 10.3390/ijms19041172
Source: check_circle
Multidisciplinary Digital Publishing Institute
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Casting a Wide Net: Role of Perineuronal Nets in Neural Plasticity

The Journal of Neuroscience
2016-11-09 | Journal article
DOI: 10.1523/JNEUROSCI.2351-16.2016
Contributors: Barbara A. Sorg; Sabina Berretta; Jordan M. Blacktop; James W. Fawcett; Hiroshi Kitagawa; Jessica C.F. Kwok; Marta Miquel
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Crossref

Full length talin stimulates integrin activation and axon regeneration

Molecular and Cellular Neuroscience
2015-09 | Journal article
DOI: 10.1016/j.mcn.2015.03.011
Contributors: Chin Lik Tan; Jessica C.F. Kwok; Janosch P.D. Heller; Rongrong Zhao; Richard Eva; James W. Fawcett
Source: check_circle
Crossref

The relationship between glial cell mechanosensitivity and foreign body reactions in the central nervous system

2014 | Journal article
DOI: 10.1016/j.biomaterials.2014.01.038
Part of ISSN: 01429612 18785905
EID:

2-s2.0-84894614410
Contributors: Moshayedi, P.; Ng, G.; Kwok, J.C.F.; Yeo, G.S.H.; Bryant, C.E.; Fawcett, J.W.; Franze, K.; Guck, J.
Source: Self-asserted source
Jessica CF Kwok via Scopus - Elsevier

Effects of digesting chondroitin sulfate proteoglycans on plasticity in cat primary visual cortex

2013 | Journal article
DOI: 10.1523/JNEUROSCI.2283-12.2013
Part of ISSN: 02706474 15292401
EID:

2-s2.0-84871803138
Contributors: Vorobyov, V.; Kwok, J.C.F.; Fawcett, J.W.; Sengpiel, F.
Source: Self-asserted source
Jessica CF Kwok via Scopus - Elsevier

Semaphorin 3A binds to the perineuronal nets via chondroitin sulfate type E motifs in rodent brains

2013 | Journal article
DOI: 10.1074/jbc.M111.310029
Part of ISSN: 00219258 1083351X
EID:

2-s2.0-84884558656
Contributors: Dick, G.; Liktan, C.; Alves, J.N.; Ehlert, E.M.E.; Miller, G.M.; Hsieh-Wilson, L.C.; Sugahara, K.; Oosterhof, A.; Van Kuppevelt, T.H.; Verhaagen, J. et al.
Source: Self-asserted source
Jessica CF Kwok via Scopus - Elsevier

The chemorepulsive axon guidance protein semaphorin3A is a constituent of perineuronal nets in the adult rodent brain

2013 | Journal article
DOI: 10.1016/j.mcn.2013.04.009
Part of ISSN: 10447431 10959327
EID:

2-s2.0-84878718336
Contributors: Vo, T.; Carulli, D.; Ehlert, E.M.E.; Kwok, J.C.F.; Dick, G.; Mecollari, V.; Moloney, E.B.; Neufeld, G.; de Winter, F.; Fawcett, J.W. et al.
Source: Self-asserted source
Jessica CF Kwok via Scopus - Elsevier

Chondroitin sulfate: A key molecule in the brain matrix

2012 | Journal article
DOI: 10.1016/j.biocel.2012.01.004
Part of ISSN: 13572725 18785875
EID:

2-s2.0-84857913115
Contributors: Kwok, J.C.F.; Warren, P.; Fawcett, J.W.
Source: Self-asserted source
Jessica CF Kwok via Scopus - Elsevier

Kindlin-1 enhances axon growth on inhibitory chondroitin sulfate proteoglycans and promotes sensory axon regeneration

2012 | Journal article
DOI: 10.1523/JNEUROSCI.5472-11.2012
Part of ISSN: 02706474 15292401
EID:

2-s2.0-84861325297
Contributors: Tan, C.L.; Andrews, M.R.; Kwok, J.C.F.; Heintz, T.G.P.; Gumy, L.F.; Fässler, R.; Fawcett, J.W.
Source: Self-asserted source
Jessica CF Kwok via Scopus - Elsevier

6-Sulphated chondroitins have a positive influence on axonal regeneration

2011 | Journal article
DOI: 10.1371/journal.pone.0021499
Part of ISSN: 19326203
EID:

2-s2.0-79959776499
Contributors: Lin, R.; Rosahl, T.W.; Whiting, P.J.; Fawcett, J.W.; Kwok, J.C.F.
Source: Self-asserted source
Jessica CF Kwok via Scopus - Elsevier

Integrin activation promotes axon growth on inhibitory chondroitin sulfate proteoglycans by enhancing integrin signaling

2011 | Journal article
DOI: 10.1523/JNEUROSCI.0008-11.2011
Part of ISSN: 02706474 15292401
EID:

2-s2.0-79955766629
Contributors: Tan, C.L.; Kwok, J.C.F.; Patani, R.; Ffrench-Constant, C.; Chandran, S.; Fawcett, J.W.
Source: Self-asserted source
Jessica CF Kwok via Scopus - Elsevier

Lentiviral vectors express chondroitinase ABC in cortical projections and promote sprouting of injured corticospinal axons

2011 | Journal article
DOI: 10.1016/j.jneumeth.2011.08.003
Part of ISSN: 01650270 1872678X
EID:

2-s2.0-80052339651
Contributors: Zhao, R.-R.; Muir, E.M.; Alves, J.N.; Rickman, H.; Allan, A.Y.; Kwok, J.C.; Roet, K.C.D.; Verhaagen, J.; Schneider, B.L.; Bensadoun, J.-C. et al.
Source: Self-asserted source
Jessica CF Kwok via Scopus - Elsevier

Animals lacking link protein have attenuated perineuronal nets and persistent plasticity

2010 | Journal article
DOI: 10.1093/brain/awq145
Part of ISSN: 00068950 14602156
EID:

2-s2.0-77955148070
Contributors: Carulli, D.; Pizzorusso, T.; Kwok, J.C.F.; Putignano, E.; Poli, A.; Forostyak, S.; Andrews, M.R.; Deepa, S.S.; Glant, T.T.; Fawcett, J.W.
Source: Self-asserted source
Jessica CF Kwok via Scopus - Elsevier

Astrocyte-produced ephrins inhibit Schwann cell migration via VAV2 signaling

2010 | Journal article
DOI: 10.1523/JNEUROSCI.3351-09.2010
Part of ISSN: 02706474 15292401
EID:

2-s2.0-77949806552
Contributors: Afshari, F.T.; Kwok, J.C.; Fawcett, J.W.
Source: Self-asserted source
Jessica CF Kwok via Scopus - Elsevier

Controlled release of chondroitinase ABC from fibrin gel reduces the level of inhibitory glycosaminoglycan chains in lesioned spinal cord

2010 | Journal article
DOI: 10.1016/j.jconrel.2010.06.026
Part of ISSN: 01683659
EID:

2-s2.0-79955064792
Contributors: Hyatt, A.J.T.; Wang, D.; Kwok, J.C.; Fawcett, J.W.; Martin, K.R.
Source: Self-asserted source
Jessica CF Kwok via Scopus - Elsevier

In vitro modeling of perineuronal nets: Hyaluronan synthase and link protein are necessary for their formation and integrity

2010 | Journal article
DOI: 10.1111/j.1471-4159.2010.06878.x
Part of ISSN: 00223042 14714159
EID:

2-s2.0-77955145653
Contributors: Kwok, J.C.F.; Carulli, D.; Fawcett, J.W.
Source: Self-asserted source
Jessica CF Kwok via Scopus - Elsevier

Integrin activation or alpha9 expression allows retinal pigmented epithelial cell adhesion on Bruch's membrane in wet age-related macular degeneration

2010 | Journal article
DOI: 10.1093/brain/awp319
Part of ISSN: 00068950 14602156
EID:

2-s2.0-77249154049
Contributors: Afshari, F.T.; Kwok, J.C.; Andrews, M.R.; Blits, B.; Martin, K.R.; Faissner, A.; Ffrench-Constant, C.; Fawcett, J.W.
Source: Self-asserted source
Jessica CF Kwok via Scopus - Elsevier

Distribution and synthesis of extracellular matrix proteoglycans, hyaluronan, link proteins and tenascin-R in the rat spinal cord

2008 | Journal article
DOI: 10.1111/j.1460-9568.2008.06108.x
Part of ISSN: 0953816X 14609568
EID:

2-s2.0-40949113724
Contributors: Galtrey, C.M.; Kwok, J.C.F.; Carulli, D.; Rhodes, K.E.; Fawcett, J.W.
Source: Self-asserted source
Jessica CF Kwok via Scopus - Elsevier

Heparan sulphate proteoglycans in glia and in the normal and injured CNS: Expression of sulphotransferases and changes in sulphation

2008 | Journal article
DOI: 10.1111/j.1460-9568.2008.06042.x
Part of ISSN: 0953816X 14609568
EID:

2-s2.0-39049110132
Contributors: Properzi, F.; Lin, R.; Kwok, J.; Naidu, M.; Van Kuppevelt, T.H.; Ten Dam, G.B.; Camargo, L.M.; Raha-Chowdhury, R.; Furukawa, Y.; Mikami, T. et al.
Source: Self-asserted source
Jessica CF Kwok via Scopus - Elsevier

Proteoglycans in the central nervous system: Plasticity, regeneration and their stimulation with chondroitinase ABC

2008 | Journal article
Part of ISSN: 09226028
EID:

2-s2.0-52649142042
Contributors: Kwok, J.C.F.; Afshari, F.; García-Alías, G.; Fawcett, J.W.
Source: Self-asserted source
Jessica CF Kwok via Scopus - Elsevier

11. Controlled release of chondroitinase ABC from fibrin gel reduces the level of inhibitory glycosaminoglycan chains in lesioned spinal cord

Journal article
Contributors: Jessica CF Kwok
Source: Self-asserted source
Jessica CF Kwok

16. Schwann cell migration is integrin-dependent and inhibited by astrocyte-produced aggrecan

Journal article
Contributors: Jessica CF Kwok
Source: Self-asserted source
Jessica CF Kwok

19. Distribution and synthesis of extracellular matrix proteoglycans, hyaluronan, link proteins and tenascin-R in the rat spinal cord

Journal article
Contributors: Jessica CF Kwok
Source: Self-asserted source
Jessica CF Kwok

6-Sulphated chondroitins have a positive influence on axonal regeneration

Journal article
Contributors: Jessica CF Kwok
Source: Self-asserted source
Jessica CF Kwok

Analysis of Schwann-astrocyte Interactions Using <em>In Vitro</em> Assays
Source: Self-asserted source
Jessica CF Kwok
grade
Preferred source (of 2)‎

Animals lacking link protein have attenuated perineuronal nets and persistent plasticity

Journal article
Contributors: Jessica CF Kwok
Source: Self-asserted source
Jessica CF Kwok

Astrocyte-produced ephrins inhibit schwann cell migration via VAV2 signaling

Journal article
Contributors: Jessica CF Kwok
Source: Self-asserted source
Jessica CF Kwok

Chondroitin sulfate: a key molecule in the brain matrix

Journal article
Contributors: Jessica CF Kwok
Source: Self-asserted source
Jessica CF Kwok

Chondroitin Sulfates in Axon Regeneration and Plasticity
Source: Self-asserted source
Jessica CF Kwok
grade
Preferred source (of 2)‎

Chondroitin sulfates in the developing rat hindbrain confine commissural projections of vestibular nuclear neurons
Source: Self-asserted source
Jessica CF Kwok
grade
Preferred source (of 2)‎

Chondroitinase ABC has a long-lasting effect on chondroitin sulphate glycosaminoglycan content in the injured rat brain
Source: Self-asserted source
Jessica CF Kwok
grade
Preferred source (of 2)‎

Effects of digesting chondroitin sulfate proteoglycans on plasticity in cat primary visual cortex

Journal article
Contributors: Jessica CF Kwok
Source: Self-asserted source
Jessica CF Kwok
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