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Scopus Author ID: 57219434947

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Employment (1)

Charles University: Prague, CZ

2019 to present | Researcher (Faculty of Pharmacy)
Employment
Source: Self-asserted source
Václav Pflégr

Education and qualifications (2)

Charles University: Hradec Králové, CZ

2018 to present | PhD. (Faculty of Pharmacy)
Education
Source: Self-asserted source
Václav Pflégr

Jan Evangelista Purkyně University in Ústí nad Labem: Ústí nad Labem, CZ

2013 to 2018 | MSc. (Faculty of Science)
Education
Source: Self-asserted source
Václav Pflégr

Works (10)

Enhancing the antimycobacterial efficacy of pyridine-4-carbohydrazide: linkage to additional antimicrobial agents via oxocarboxylic acids

RSC Medicinal Chemistry
2025 | Journal article
DOI: 10.1039/D4MD00663A
Contributors: Václav Pflégr; Klára Konečná; Jiřina Stolaříková; Jan Ősterreicher; Ondřej Janďourek; Martin Krátký
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Novel Pyrimidine-1,3,4-Oxadiazole Hybrids and Their Precursors As Potential Antimycobacterial Agents

Future Medicinal Chemistry
2023-06 | Journal article
DOI: 10.4155/fmc-2023-0096
Contributors: Václav Pflégr; Jiřina Stolaříková; Adrián Pál; Jana Korduláková; Martin Krátký
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Crossref

Novel Inhibitors of Acetyl- and Butyrylcholinesterase Derived from Benzohydrazides: Synthesis, Evaluation and Docking Study

Pharmaceuticals
2023-01-24 | Journal article
DOI: 10.3390/ph16020172
Contributors: Neto-Honorius Houngbedji; Šárka Štěpánková; Václav Pflégr; Katarína Svrčková; Markéta Švarcová; Jarmila Vinšová; Martin Krátký
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Synthesis and Antimycobacterial Activity of Isoniazid Derivatives Tethered with Aliphatic Amines

Current Topics in Medicinal Chemistry
2022-12 | Journal article
DOI: 10.2174/1568026622666220805152811
Contributors: Václav Pflégr; Jiřina Stolaříková; Jarmila Vinšová; Martin Krátký
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5-Aryl-1,3,4-oxadiazol-2-amines Decorated with Long Alkyl and Their Analogues: Synthesis, Acetyl- and Butyrylcholinesterase Inhibition and Docking Study

Pharmaceuticals
2022-03 | Journal article | Author
DOI: 10.3390/ph15040400
Contributors: Václav Pflégr; Šárka Štěpánková; Katarina Svrckova; Markéta Švarcová; Jarmila Vinšová; Martin Kratky
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Multidisciplinary Digital Publishing Institute
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Design and Synthesis of Highly Active Antimycobacterial Mutual Esters of 2-(2-Isonicotinoylhydrazineylidene)propanoic Acid

Pharmaceuticals
2021-12-14 | Journal article
DOI: 10.3390/ph14121302
Contributors: Václav Pflégr; Jana Maixnerová; Jiřina Stolaříková; Adrián Pál; Jana Korduláková; František Trejtnar; Jarmila Vinšová; Martin Krátký
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Crossref
grade
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Design and synthesis of 2-(2-isonicotinoylhydrazineylidene)propanamides as InhA inhibitors with high antitubercular activity

European Journal of Medicinal Chemistry
2021-11 | Journal article
DOI: 10.1016/j.ejmech.2021.113668
Part of ISSN: 0223-5234
Source: Self-asserted source
Václav Pflégr
grade
Preferred source (of 2)‎

Novel propargylamine-based inhibitors of cholinesterases and monoamine oxidases: Synthesis, biological evaluation and docking study

Bioorganic Chemistry
2021-11 | Journal article
DOI: 10.1016/j.bioorg.2021.105301
Part of ISSN: 0045-2068
Source: Self-asserted source
Václav Pflégr

Iodinated 1,2-diacylhydrazines, benzohydrazide-hydrazones and their analogues as dual antimicrobial and cytotoxic agents

Bioorganic & Medicinal Chemistry
2021-07 | Journal article
DOI: 10.1016/j.bmc.2021.116209
Part of ISSN: 0968-0896
Source: Self-asserted source
Václav Pflégr
grade
Preferred source (of 2)‎

N-[3,5-Bis(trifluoromethyl)phenyl]-5-bromo-2-hydroxybenzamide Analogues: Novel Acetyl- and Butyrylcholinesterase Inhibitors

Current Topics in Medicinal Chemistry
2020-10-12 | Journal article
DOI: 10.2174/1568026620666200819154722
Contributors: Martin Krátký; Karolína Jaklová; Šárka Štěpánková; Katarína Svrčková; Václav Pflégr; Jarmila Vinšová
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Crossref
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