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Scopus Author ID: 55308180900
ResearcherID: R-6774-2018
Scopus Author ID: 56545728100
SciProfiles: 683567

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Czech Republic

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Employment (1)

Palacký University, Olomouc: Olomouc, CZ

2004-08-01 to present (Faculty of medicine and dentistry)
Employment
Source: Self-asserted source
Alena Špičáková

Education and qualifications (3)

Palacký University, Olomouc: Olomouc, CZ

2012-09-01 to 2020-01-24 | Ph.D. (Faculty of medicine and dentistry)
Education
Source: Self-asserted source
Alena Špičáková

Palacký University, Olomouc: Olomouc, CZ

2006-09-01 to 2008-06-30 | Mgr. (Faculty of Science)
Education
Source: Self-asserted source
Alena Špičáková

Palacký University, Olomouc: Olomouc, CZ

2001-09-01 to 2004-06-30 | Bc. (Faculty of Science)
Education
Source: Self-asserted source
Alena Špičáková

Works (26)

<i>In Vitro</i> Interaction of Binuclear Copper Complexes with Liver Drug-Metabolizing Cytochromes P450

Pharmaceuticals
2024-09 | Journal article | Author
DOI: 10.3390/ph17091194
Contributors: Alena Špičáková; Zuzana Horáčková; Pavel Kopel; PAVEL ANZENBACHER
Source: check_circle
Multidisciplinary Digital Publishing Institute

Lipophosphonoxins—A Novel Group of Broad Spectrum Antibacterial Compounds

Pharmaceutics
2023-09 | Journal article | Author
DOI: 10.3390/pharmaceutics15102395
Contributors: Viktor Šebek; Pavel Anzenbacher; Dominik Rejman; Alena Špičáková; Milan Kolář
Source: check_circle
Multidisciplinary Digital Publishing Institute

Structure–Activity Relationship of para-Carborane Selective Estrogen Receptor β Agonists

Journal of Medicinal Chemistry
2021-07-08 | Journal article
DOI: 10.1021/acs.jmedchem.1c00555
Part of ISSN: 0022-2623
Part of ISSN: 1520-4804
Source: Self-asserted source
Alena Špičáková

in vitro and in silico studies of interaction of synthetic 2,6,9-trisubstituted purine kinase inhibitors BPA-302, BP-21 and BP-117 with liver drug-metabolizing cytochromes P450

Physiological Research
2020-12-31 | Journal article
DOI: 10.33549/physiolres.934611
Part of ISSN: 1802-9973
Part of ISSN: 0862-8408
Source: Self-asserted source
Alena Špičáková
grade
Preferred source (of 2)‎

Hepatocellular carcinoma: Gene expression profiling and regulation of xenobiotic-metabolizing cytochromes P450

Biochemical Pharmacology
2020-03-13 | Journal article
DOI: 10.1016/j.bcp.2020.113912
Part of ISSN: 0006-2952
Source: Self-asserted source
Alena Špičáková
grade
Preferred source (of 2)‎

β‐caryophyllene Oxide and Trans-nerolidol Affect Enzyme Activity of CYP3A4 – In Vitro and In Silico Studies

Physiological Research
2019-10-31 | Journal article
DOI: 10.33549/physiolres.934323
Part of ISSN: 1802-9973
Part of ISSN: 0862-8408
Source: Self-asserted source
Alena Špičáková
grade
Preferred source (of 2)‎

Nerolidol and farnesol inhibit some cytochrome P450 activities but did not affect other xenobiotic-metabolizing enzymes in rat and human hepatic subcellular fractions

Molecules
2017 | Journal article
DOI: 10.3390/molecules22040509
Source: Self-asserted source
Alena Špičáková
grade
Preferred source (of 4)‎

The inhibitory effects of β-caryophyllene, β-caryophyllene oxide and α-humulene on the activities of the main drug-metabolizing enzymes in rat and human liver in vitro

Chemico-Biological Interactions
2017 | Journal article
DOI: 10.1016/j.cbi.2017.10.021
Source: Self-asserted source
Alena Špičáková
grade
Preferred source (of 3)‎

Evaluation of possible inhibition of human liver drug metabolizing cytochromes P450 by two new acetylcholinesterase oxime-type reactivators

Food and Chemical Toxicology
2016 | Journal article
DOI: 10.1016/j.fct.2015.11.024
Source: Self-asserted source
Alena Špičáková
grade
Preferred source (of 3)‎

Interaction of rocuronium with human liver cytochromes P450

Journal of Pharmacological Sciences
2015 | Journal article
DOI: 10.1016/j.jphs.2014.12.006
Source: Self-asserted source
Alena Špičáková
grade
Preferred source (of 3)‎

Interaction of anthocyanins with human liver microsomal cytochromes P450

Biomedical Papers-Olomouc
2013 | Journal article
WOSUID:

WOS:000324728600003
Contributors: Zapletalova, Michaela Kopecna; Vanduchova, Alena; Spicakova, Alena; Anzenbacherova, Eva; Anzenbacher, Pavel
Source: Self-asserted source
Alena Špičáková via ResearcherID

Interaction of anthocyanidins with human liver microsomal cytochromes P450 1A2 and 3A4 in vitro

Febs Journal
2012 | Journal article
WOSUID:

WOS:000308128602320
Contributors: Spicakova, A.; Anzenbacherova, E.
Source: Self-asserted source
Alena Špičáková via ResearcherID

Rosuvastatin suppresses the liver microsomal CYP2C11 and CYP2C6 expression in male Wistar rats

Xenobiotica
2012 | Journal article
DOI: 10.3109/00498254.2012.661099
Source: Self-asserted source
Alena Špičáková
grade
Preferred source (of 3)‎

Effects of Lactobacillus casei on the expression and activity of cytochromes P450 in the liver and the intestine of male rat

Febs Journal
2011 | Journal article
WOSUID:

WOS:000292333101306
Contributors: Matuskova, Z.; Tunkova, A.; Anzenbacherova, E.; Zacharova, A.; Tlaskalova-Hogenova, H.; Zidek, Z.; Anzenbacher, P.
Source: Self-asserted source
Alena Špičáková via ResearcherID

Effects of Lactobacillus casei on the expression and the activity of cytochromes P450 and on the CYP mRNA level in the intestine and the liver of male rats

Neuroendocrinology Letters
2011 | Journal article
WOSUID:

WOS:000300544100002
Contributors: Matuskova, Zuzana; Siller, Michal; Tunkova, Alena; Anzenbacherova, Eva; Zacharova, Alice; Hogenova, Helena Tlaskalova; Zidek, Zdenek; Anzenbacher, Pavel
Source: Self-asserted source
Alena Špičáková via ResearcherID

Effects of probiotic Escherichia coli Nissle 1917 on expression of cytochromes P450 along the gastrointestinal tract of male rats

Neuroendocrinology Letters
2010 | Journal article
WOSUID:

WOS:000288061000009
Contributors: Matuskova, Zuzana; Tunkova, Alena; Anzenbacherova, Eva; Vecera, Rostislav; Siller, Michal; Tlaskalova-Hogenova, Helena; Zidek, Zdenek; Anzenbacher, Pavel
Source: Self-asserted source
Alena Špičáková via ResearcherID

Effect of acetylcholinesterase oxime-type reactivators K-48 and HI-6 on human liver microsomal cytochromes P450 in vitro

Chemico-Biological Interactions
2009 | Journal article
DOI: 10.1016/j.cbi.2009.03.016
Source: Self-asserted source
Alena Špičáková
grade
Preferred source (of 2)‎

Influence of probiotics on rat Liver biotransformation enzymes

Neuroendocrinology Letters
2009 | Journal article
WOSUID:

WOS:000275266600010
Contributors: Matuskova, Zuzana; Tunkova, Alena; Anzenbacherova, Eva; Zidek, Zdenek; Tlaskalova-Hogenova, Helena; Anzenbacher, Pavel
Source: Self-asserted source
Alena Špičáková via ResearcherID

Isolation of two cytochrome P450 forms, CYP2A19 and CYP1A, from pig liver microsomes

Journal of Veterinary Pharmacology and Therapeutics
2009 | Journal article
DOI: 10.1111/j.1365-2885.2009.01076.x
Source: Self-asserted source
Alena Špičáková
grade
Preferred source (of 2)‎

On the possibility of interactions of rocuronium with liver microsomal cytochromes P450 [Možné interakce rokuronia s jaterními mikrosomálními cytochromy P450]

Klinicka Farmakologie a Farmacie
2009 | Journal article
Source: Self-asserted source
Alena Špičáková

Porcine CYP2A19, CYP2E1 and CYP1A2 forms are responsible for skatole biotransformation in the reconstituted system

Neuroendocrinology Letters
2009 | Journal article
WOSUID:

WOS:000275266600009
Contributors: Matal, Jaroslav; Matuskova, Zuzana; Tunkova, Alena; Anzenbacherova, Eva; Anzenbacher, Pavel
Source: Self-asserted source
Alena Špičáková via ResearcherID

In Vivo Study of the Effect of Antiviral Acyclic Nucleotide Phosphonate (R)-9-[2-(phosphonomethoxy)propyl]adenine (PMPA, tenofovir) and Its Prodrug Tenofovir Disoproxil Fumarate on Rat Microsomal Cytochrome P450

Physiological Research
2008 | Journal article
WOSUID:

WOS:000260893500013
Contributors: Anzenbacherova, E.; Anzenbacher, P.; Zidek, Z.; Buchar, E.; Kmonickova, E.; Potmesil, P.; Nekvindova, J.; Veinlichova, A.; Holy, A.
Source: Self-asserted source
Alena Špičáková via ResearcherID

Silybin is metabolized by cytochrome P450 2C8 in vitro

Drug Metabolism and Disposition
2007 | Journal article
DOI: 10.1124/dmd.107.016410
Source: Self-asserted source
Alena Špičáková
grade
Preferred source (of 2)‎

Experimental approaches to studies on drug metabolism and drug interactions in man: interaction of acyclic nucleoside phosphonates with human liver cytochromes P450 and flavin-containing monooxygenase 3

Neuroendocrinology Letters
2006 | Journal article
WOSUID:

WOS:000245442600007
Contributors: Matal, Jaroslav; Orsag, Jiri; Nekvindova, Jana; Anzenbacherova, Eva; Veinlichova, Alena; Anzenbacher, Pavel; Zidek, Zdenek; Holy, Antonin
Source: Self-asserted source
Alena Špičáková via ResearcherID

Inhibition of human liver microsomal cytochrome P450 activities by adefovir and tenofovir

Xenobiotica
2006 | Journal article
DOI: 10.1080/00498250600839344
Source: Self-asserted source
Alena Špičáková
grade
Preferred source (of 2)‎

Comparison of "high throughput" micromethods for determination of cytochrome P450 activities with classical methods using HPLC for product identification.

Biomedical papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia
2005 | Journal article
DOI: 10.5507/bp.2005.057
Source: Self-asserted source
Alena Špičáková
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