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Works (21)

EPSILON: a method for pulse-chase labeling to probe synaptic AMPAR exocytosis during memory formation

Nature Neuroscience
2025-03-31 | Journal article
DOI: 10.1038/s41593-025-01922-5
Contributors: Doyeon Kim; Pojeong Park; Xiuyuan Li; J. David Wong-Campos; He Tian; Eric M. Moult; Jonathan B. Grimm; Luke D. Lavis; Adam E. Cohen
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Dendritic excitations govern back-propagation via a spike-rate accelerometer

Nature Communications
2025-02-04 | Journal article
DOI: 10.1038/s41467-025-55819-9
Contributors: Pojeong Park; J. David Wong-Campos; Daniel G. Itkis; Byung Hun Lee; Yitong Qi; Hunter C. Davis; Benjamin Antin; Amol Pasarkar; Jonathan B. Grimm; Sarah E. Plutkis et al.
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Evaluation of the Cytosolic Uptake of HaloTag Using a pH-Sensitive Dye

ACS Chemical Biology
2024-04-19 | Journal article
DOI: 10.1021/acschembio.3c00713
Contributors: JoLynn B. Giancola; Jonathan B. Grimm; Joomyung V. Jun; Yana D. Petri; Luke D. Lavis; Ronald T. Raines
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A series of spontaneously blinking dyes for super-resolution microscopy

2024-02-24 | Preprint
DOI: 10.1101/2024.02.23.581625
Contributors: Katie L. Holland; Sarah E. Plutkis; Timothy A. Daugird; Abhishek Sau; Jonathan B. Grimm; Brian P. English; Qinsi Zheng; Sandeep Dave; Fariha Rahman; Liangqi Xie et al.
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Optimized Red-Absorbing Dyes for Imaging and Sensing

Journal of the American Chemical Society
2023-10-25 | Journal article
DOI: 10.1021/jacs.3c05273
Contributors: Jonathan B. Grimm; Ariana N. Tkachuk; Ronak Patel; S. Thomas Hennigan; Alina Gutu; Peng Dong; Valentina Gandin; Anastasia M. Osowski; Katie L. Holland; Zhe J. Liu et al.
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A modular chemigenetic calcium indicator enables in vivo functional imaging with near-infrared light

2023-07-19 | Preprint
DOI: 10.1101/2023.07.18.549527
Contributors: Helen Farrants; Yichun Shuai; William C. Lemon; Christian Monroy Hernandez; Shang Yang; Ronak Patel; Guanda Qiao; Michelle S. Frei; Jonathan B. Grimm; Timothy L. Hanson et al.
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Time-tagged ticker tapes for intracellular recordings

Nature Biotechnology
2023-05 | Journal article
DOI: 10.1038/s41587-022-01524-7
Contributors: Dingchang Lin; Xiuyuan Li; Eric Moult; Pojeong Park; Benjamin Tang; Hao Shen; Jonathan B. Grimm; Natalie Falco; Bill Z. Jia; David Baker et al.
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Brain-wide measurement of synaptic protein turnover reveals localized plasticity during learning

2022-11-13 | Preprint
DOI: 10.1101/2022.11.12.516226
Contributors: Boaz Mohar; Gabriela Michel; Yi-Zhi Wang; Veronica Hernandez; Jonathan B. Grimm; Jin-Yong Park; Ronak Patel; Morgan Clarke; Timothy A. Brown; Cornelius Bergmann et al.
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Optimizing multifunctional fluorescent ligands for intracellular labeling

2022-07-03 | Preprint
DOI: 10.1101/2022.07.02.498544
Contributors: Pratik Kumar; Jason D. Vevea; Ariana N. Tkachuk; Kirby Campbell; Emma T. Watson; Anthony X. Ayala; Jonathan B. Grimm; Edwin R. Chapman; David J. Solecki; Luke D. Lavis
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Caveat fluorophore: an insiders’ guide to small-molecule fluorescent labels

Nature Methods
2022-02 | Journal article
DOI: 10.1038/s41592-021-01338-6
Contributors: Jonathan B. Grimm; Luke D. Lavis
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Biosensors based on peptide exposure show single molecule conformations in live cells

Cell
2021-10 | Journal article
DOI: 10.1016/j.cell.2021.09.026
Contributors: Bei Liu; Orrin J. Stone; Michael Pablo; J. Cody Herron; Ana T. Nogueira; Onur Dagliyan; Jonathan B. Grimm; Luke D. Lavis; Timothy C. Elston; Klaus M. Hahn
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Enabling In Vivo Photocatalytic Activation of Rapid Bioorthogonal Chemistry by Repurposing Silicon-Rhodamine Fluorophores as Cytocompatible Far-Red Photocatalysts

Journal of the American Chemical Society
2021-07-21 | Journal article
DOI: 10.1021/jacs.1c05547
Contributors: Chuanqi Wang; He Zhang; Tao Zhang; Xiaoyu Zou; Hui Wang; Julia E. Rosenberger; Raghu Vannam; William S. Trout; Jonathan B. Grimm; Luke D. Lavis et al.
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A General Method to Improve Fluorophores Using Deuterated Auxochromes

JACS Au
2021-05-24 | Journal article
DOI: 10.1021/jacsau.1c00006
Contributors: Jonathan B. Grimm; Liangqi Xie; Jason C. Casler; Ronak Patel; Ariana N. Tkachuk; Natalie Falco; Heejun Choi; Jennifer Lippincott-Schwartz; Timothy A. Brown; Benjamin S. Glick et al.
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Novel Fluorescent Ligands Enable Single-Molecule Localization Microscopy of the Dopamine Transporter

ACS Chemical Neuroscience
2020-10-21 | Journal article
DOI: 10.1021/acschemneuro.0c00397
Contributors: Daryl A. Guthrie; Carmen Klein Herenbrink; Matthew Domenic Lycas; Therese Ku; Alessandro Bonifazi; Brian T. DeVree; Signe Mathiasen; Jonathan A. Javitch; Jonathan B. Grimm; Luke Lavis et al.
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A general method to optimize and functionalize red-shifted rhodamine dyes

Nature Methods
2020-08 | Journal article
DOI: 10.1038/s41592-020-0909-6
Contributors: Jonathan B. Grimm; Ariana N. Tkachuk; Liangqi Xie; Heejun Choi; Boaz Mohar; Natalie Falco; Kathy Schaefer; Ronak Patel; Qinsi Zheng; Zhe Liu et al.
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Rational Design of Bioavailable Photosensitizers for Manipulation and Imaging of Biological Systems

Cell Chemical Biology
2020-08 | Journal article
DOI: 10.1016/j.chembiol.2020.07.001
Contributors: Thomas C. Binns; Anthony X. Ayala; Jonathan B. Grimm; Ariana N. Tkachuk; Guillaume A. Castillon; Sebastien Phan; Lixia Zhang; Timothy A. Brown; Zhe Liu; Stephen R. Adams et al.
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Deuteration improves small-molecule fluorophores

2020-08-17 | Preprint
DOI: 10.1101/2020.08.17.250027
Contributors: Jonathan B. Grimm; Liangqi Xie; Jason C. Casler; Ronak Patel; Ariana N. Tkachuk; Heejun Choi; Jennifer Lippincott-Schwartz; Timothy A. Brown; Benjamin S. Glick; Zhe Liu et al.
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Optimization and functionalization of red-shifted rhodamine dyes

2019-12-20 | Preprint
DOI: 10.1101/2019.12.20.881227
Contributors: Jonathan B. Grimm; Ariana N. Tkachuk; Heejun Choi; Boaz Mohar; Natalie Falco; Ronak Patel; Jennifer Lippincott-Schwartz; Timothy A. Brown; Luke D. Lavis
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Rational Design of Fluorogenic and Spontaneously Blinking Labels for Super-Resolution Imaging

ACS Central Science
2019-09-25 | Journal article
DOI: 10.1021/acscentsci.9b00676
Contributors: Qinsi Zheng; Anthony X. Ayala; Inhee Chung; Aubrey V. Weigel; Anand Ranjan; Natalie Falco; Jonathan B. Grimm; Ariana N. Tkachuk; Carl Wu; Jennifer Lippincott-Schwartz et al.
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Whole-Cell, 3D, and Multicolor STED Imaging with Exchangeable Fluorophores

Nano Letters
2019-01-09 | Journal article
DOI: 10.1021/acs.nanolett.8b04385
Contributors: Christoph Spahn; Jonathan B. Grimm; Luke D. Lavis; Marko Lampe; Mike Heilemann
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Cell-Specific Chemical Delivery Using a Selective Nitroreductase–Nitroaryl Pair

ACS Chemical Biology
2018-10-19 | Journal article
DOI: 10.1021/acschembio.8b00524
Contributors: Todd D. Gruber; Chithra Krishnamurthy; Jonathan B. Grimm; Michael R. Tadross; Laura M. Wysocki; Zev J. Gartner; Luke D. Lavis
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