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Scopus Author ID: 6602363614

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Works (43)

A yeast-based high-throughput screen identifies inhibitors of trypanosomatid HRG heme transporters with potent leishmanicidal and trypanocidal activity

International Journal of Antimicrobial Agents
2024-03 | Journal article
DOI: 10.1016/j.ijantimicag.2024.107092
Contributors: María Cabello-Donayre; Irene Cabello-Donayre; Diego Guerra; Lina M. Orrego; Juan C. Morales; Bastien Cautain; Francisca Vicente; José M. Pérez-Victoria
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FiCRoN, a deep learning-based algorithm for the automatic determination of intracellular parasite burden from fluorescence microscopy images

Medical Image Analysis
2024-01 | Journal article
DOI: 10.1016/j.media.2023.103036
Contributors: Graciela Juez-Castillo; Brayan Valencia-Vidal; Lina M. Orrego; María Cabello-Donayre; Laura Montosa-Hidalgo; José M. Pérez-Victoria
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New Insights on Heme Uptake in Leishmania spp.

International Journal of Molecular Sciences
2022-09-10 | Journal article
DOI: 10.3390/ijms231810501
Contributors: María Cabello-Donayre; Lina M. Orrego; Elisa Herráez; Raquel García-Hernández; José M. Pérez-Victoria
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Haem-responsive gene transporter enables mobilization of host haem in ticks

Open Biology
2021-09 | Journal article
DOI: 10.1098/rsob.210048
Contributors: J. Perner; T. Hatalova; M. Cabello-Donayre; V. Urbanova; D. Sojka; H. Frantova; D. Hartmann; D. Jirsova; J. M. Pérez-Victoria; P. Kopacek
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Leishmania heme uptake involves LmFLVCRb, a novel porphyrin transporter essential for the parasite

Cellular and Molecular Life Sciences
2020-05-01 | Journal article
DOI: 10.1007/s00018-019-03258-3
Contributors: María Cabello-Donayre; Lina M. Orrego; Elisa Herráez; Paola Vargas; Marta Martínez-García; Jenny Campos-Salinas; Ignacio Pérez-Victoria; Belén Vicente; José J. G. Marín; José M. Pérez-Victoria
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Carbohydrate-naphthalene diimide conjugates as potential antiparasitic drugs: Synthesis, evaluation and structure-activity studies

European Journal of Medicinal Chemistry
2019 | Journal article
DOI: 10.1016/j.ejmech.2018.11.043
EID:

2-s2.0-85057317095
Contributors: Zuffo, M.; Stucchi, A.; Campos-Salinas, J.; Cabello-Donayre, M.; Martínez-García, M.; Belmonte-Reche, E.; Pérez-Victoria, J.M.; Mergny, J.L.; Freccero, M.; Morales, J.C. et al.
Source: Self-asserted source
José María Pérez-Victoria via Scopus - Elsevier

Autophagic-related cell death of Trypanosoma brucei induced by bacteriocin AS-48

International Journal for Parasitology: Drugs and Drug Resistance
2018 | Journal article
DOI: 10.1016/j.ijpddr.2018.03.002
EID:

2-s2.0-85045026496
Contributors: Martínez-García, M.; Bart, J.-M.; Campos-Salinas, J.; Valdivia, E.; Martínez-Bueno, M.; González-Rey, E.; Navarro, M.; Maqueda, M.; Cebrián, R.; Pérez-Victoria, J.M.
Source: Self-asserted source
José María Pérez-Victoria via Scopus - Elsevier

G-Quadruplex Identification in the Genome of Protozoan Parasites Points to Naphthalene Diimide Ligands as New Antiparasitic Agents

Journal of Medicinal Chemistry
2018 | Journal article
DOI: 10.1021/acs.jmedchem.7b01672
EID:

2-s2.0-85041920828
Contributors: Belmonte-Reche, E.; Martínez-García, M.; Guédin, A.; Zuffo, M.; Arévalo-Ruiz, M.; Doria, F.; Campos-Salinas, J.; Maynadier, M.; López-Rubio, J.J.; Freccero, M. et al.
Source: Self-asserted source
José María Pérez-Victoria via Scopus - Elsevier

Semisynthesis of ω-Hydroxyalkylcarbonate Derivatives of Hydroxytyrosol as Antitrypanosome Agents

Journal of Natural Products
2018 | Journal article
DOI: 10.1021/acs.jnatprod.8b00431
EID:

2-s2.0-85052886485
Contributors: Fernandez-Pastor, I.; Martínez-García, M.; Medina-O'Donnell, M.; Rivas, F.; Martinez, A.; Pérez-Victoria, J.M.; Parra, A.
Source: Self-asserted source
José María Pérez-Victoria via Scopus - Elsevier

Synthesis, Binding Properties, and Differences in Cell Uptake of G-Quadruplex Ligands Based on Carbohydrate Naphthalene Diimide Conjugates

Chemistry - A European Journal
2017 | Journal article
DOI: 10.1002/chem.201604886
EID:

2-s2.0-85009452997
Contributors: Arévalo-Ruiz, M.; Doria, F.; Belmonte-Reche, E.; De Rache, A.; Campos-Salinas, J.; Lucas, R.; Falomir, E.; Carda, M.; Pérez-Victoria, J.M.; Mergny, J.-L. et al.
Source: Self-asserted source
José María Pérez-Victoria via Scopus - Elsevier

LmABCB3, an atypical mitochondrial ABC transporter essential for Leishmania major virulence, acts in heme and cytosolic iron/sulfur clusters biogenesis

Parasites and Vectors
2016 | Journal article
DOI: 10.1186/s13071-015-1284-5
EID:

2-s2.0-84952815636
Contributors: Martínez-García, M.; Campos-Salinas, J.; Cabello-Donayre, M.; Pineda-Molina, E.; Gálvez, F.J.; Orrego, L.M.; Sánchez-Cañete, M.P.; Malagarie-Cazenave, S.; Koeller, D.M.; Pérez-Victoria, J.M.
Source: Self-asserted source
José María Pérez-Victoria via Scopus - Elsevier

Trypanosomatid parasites rescue heme from endocytosed hemoglobin through lysosomal HRG transporters

Molecular Microbiology
2016 | Journal article
DOI: 10.1111/mmi.13430
EID:

2-s2.0-84985919962
Contributors: Cabello-Donayre, M.; Malagarie-Cazenave, S.; Campos-Salinas, J.; Gálvez, F.J.; Rodríguez-Martínez, A.; Pineda-Molina, E.; Orrego, L.M.; Martínez-García, M.; Sánchez-Cañete, M.P.; Estévez, A.M. et al.
Source: Self-asserted source
José María Pérez-Victoria via Scopus - Elsevier

Tyrosol and hydroxytyrosol derivatives as antitrypanosomal and antileishmanial agents

European Journal of Medicinal Chemistry
2016 | Journal article
DOI: 10.1016/j.ejmech.2016.04.047
EID:

2-s2.0-84968645234
Contributors: Belmonte-Reche, E.; Martínez-García, M.; Peñalver, P.; Gómez-Pérez, V.; Lucas, R.; Gamarro, F.; Pérez-Victoria, J.M.; Morales, J.C.
Source: Self-asserted source
José María Pérez-Victoria via Scopus - Elsevier

Hemolytic activity and solubilizing capacity of raffinose and melezitose fatty acid monoesters prepared by enzymatic synthesis

European Journal of Pharmaceutics and Biopharmaceutics
2015 | Journal article
DOI: 10.1016/j.ejpb.2015.02.023
EID:

2-s2.0-84925371124
Contributors: Carvalho, L.; Morales, J.C.; Pérez-Victoria, J.M.; Pérez-Victoria, I.
Source: Self-asserted source
José María Pérez-Victoria via Scopus - Elsevier

The oral antimalarial drug tafenoquine shows activity against Trypanosoma brucei

Antimicrobial Agents and Chemotherapy
2015 | Journal article
DOI: 10.1128/AAC.00879-15
EID:

2-s2.0-84942931350
Contributors: Carvalho, L.; Martínez-García, M.; Pérez-Victoria, I.; Manzano, J.I.; Yardley, V.; Gamarro, F.; Pérez-Victoria, J.M.
Source: Self-asserted source
José María Pérez-Victoria via Scopus - Elsevier

LABCG2, a New ABC Transporter Implicated in Phosphatidylserine Exposure, Is Involved in the Infectivity and Pathogenicity of Leishmania

PLoS Neglected Tropical Diseases
2013 | Journal article
DOI: 10.1371/journal.pntd.0002179
EID:

2-s2.0-84876831551
Contributors: Campos-Salinas, J.; León-Guerrero, D.; González-Rey, E.; Delgado, M.; Castanys, S.; Pérez-Victoria, J.M.; Gamarro, F.
Source: Self-asserted source
José María Pérez-Victoria via Scopus - Elsevier

A new ATP-binding cassette protein is involved in intracellular haem trafficking in Leishmania

Molecular Microbiology
2011 | Journal article
DOI: 10.1111/j.1365-2958.2010.07531.x
EID:

2-s2.0-79952441522
Contributors: Campos-Salinas, J.; Cabello-Donayre, M.; García-Hernández, R.; Pérez-Victoria, I.; Castanys, S.; Gamarro, F.; Pérez-Victoria, J.M.
Source: Self-asserted source
José María Pérez-Victoria via Scopus - Elsevier

Increased glycolytic ATP synthesis is associated with tafenoquine resistance in Leishmania major

Antimicrobial Agents and Chemotherapy
2011 | Journal article
DOI: 10.1128/AAC.01545-10
EID:

2-s2.0-79952356991
Contributors: Manzano, J.I.; Carvalho, L.; Pérez-Victoria, J.M.; Castanys, S.; Gamarro, F.
Source: Self-asserted source
José María Pérez-Victoria via Scopus - Elsevier

Non-reducing trisaccharide fatty acid monoesters: Novel detergents in membrane biochemistry

Biochimica et Biophysica Acta - Biomembranes
2011 | Journal article
DOI: 10.1016/j.bbamem.2010.11.031
EID:

2-s2.0-78650733034
Contributors: Pérez-Victoria, I.; Pérez-Victoria, F.J.; Roldán-Vargas, S.; García-Hernández, R.; Carvalho, L.; Castanys, S.; Gamarro, F.; Morales, J.C.; Pérez-Victoria, J.M.
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José María Pérez-Victoria via Scopus - Elsevier

Sitamaquine overcomes ABC-mediated resistance to miltefosine and antimony in Leishmania

Antimicrobial Agents and Chemotherapy
2011 | Journal article
DOI: 10.1128/AAC.00065-11
EID:

2-s2.0-79960312292
Contributors: Pérez-Victoria, J.M.; Bavchvarov, B.I.; Torrecillas, I.R.; Martínez-García, M.; López-Martín, C.; Campillo, M.; Castanys, S.; Gamarro, F.
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José María Pérez-Victoria via Scopus - Elsevier

Insect cell versus bacterial overexpressed membrane proteins: an example, the human ABCG2 transporter.

Methods in molecular biology (Clifton, N.J.)
2010 | Journal article
DOI: 10.1007/978-1-60761-762-4_4
EID:

2-s2.0-78049504991
Contributors: Pozza, A.; Pérez-Victoria, J.M.; Di Pietro, A.
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José María Pérez-Victoria via Scopus - Elsevier

Corrigendum to "Overexpression of homogeneous and active ABCG2 in insect cells" [Protein Express. Purif. 63 (2009) 75-83] (DOI:10.1016/j.pep.2008.09.021)

Protein Expression and Purification
2009 | Journal article
DOI: 10.1016/j.pep.2008.12.008
EID:

2-s2.0-60349112138
Contributors: Pozza, A.; Pérez-Victoria, J.M.; Pietro, A.D.
Source: Self-asserted source
José María Pérez-Victoria via Scopus - Elsevier

Characterization of an ABCG-like transporter from the protozoan parasite Leishmania with a role in drug resistance and transbilayer lipid movement

Antimicrobial Agents and Chemotherapy
2008 | Journal article
DOI: 10.1128/AAC.00587-08
EID:

2-s2.0-54049089634
Contributors: Castanys-Muñoz, E.; Pérez-Victoria, J.M.; Gamarro, F.; Castanys, S.
Source: Self-asserted source
José María Pérez-Victoria via Scopus - Elsevier

Sitamaquine sensitivity in Leishmania species is not mediated by drug accumulation in acidocalcisomes

Antimicrobial Agents and Chemotherapy
2008 | Journal article
DOI: 10.1128/AAC.00964-08
EID:

2-s2.0-55849137267
Contributors: López-Martín, C.; Pérez-Victoria, J.M.; Carvalho, L.; Castanys, S.; Gamarro, F.
Source: Self-asserted source
José María Pérez-Victoria via Scopus - Elsevier

Combination of suboptimal doses of inhibitors targeting different domains of LtrMDR1 efficiently overcomes resistance of Leishmania spp. to miltefosine by inhibiting drug efflux

Antimicrobial Agents and Chemotherapy
2006 | Journal article
DOI: 10.1128/AAC.00423-06
EID:

2-s2.0-33748687037
Contributors: Pérez-Victoria, J.M.; Cortés-Selva, F.; Parodi-Talice, A.; Bavchvarov, B.I.; Pérez-Victoria, F.J.; Muñoz-Martínez, F.; Maitrejean, M.; Costi, M.P.; Barron, D.; Di Pietro, A. et al.
Source: Self-asserted source
José María Pérez-Victoria via Scopus - Elsevier

Inhibitors of cancer cell multidrug resistance mediated by breast cancer resistance protein (BCRP/ABCG2)

Anti-Cancer Drugs
2006 | Journal article
DOI: 10.1097/00001813-200603000-00001
EID:

2-s2.0-33646087883
Contributors: Ahmed-Belkacem, A.; Pozza, A.; Macalou, S.; Pérez-Victoria, J.M.; Boumendjel, A.; Di Pietro, A.
Source: Self-asserted source
José María Pérez-Victoria via Scopus - Elsevier

Purification of breast cancer resistance protein ABCG2 and role of arginine-482

Cellular and Molecular Life Sciences
2006 | Journal article
DOI: 10.1007/s00018-006-6159-7
EID:

2-s2.0-33747216808
Contributors: Pozza, A.; Perez-Victoria, J.M.; Sardo, A.; Ahmed-Belkacem, A.; Di Pietro, A.
Source: Self-asserted source
José María Pérez-Victoria via Scopus - Elsevier

Flavonoid structure-activity studies identify 6-prenylchrysin and tectochrysin as potent and specific inhibitors of breast cancer resistance protein ABCG2

Cancer Research
2005 | Journal article
DOI: 10.1158/0008-5472.CAN-04-1817
EID:

2-s2.0-19644378841
Contributors: Ahmed-Belkacem, A.; Pozza, A.; Muñoz-Martínez, F.; Bates, S.E.; Castanys, S.; Gamarro, F.; Pietro, A.D.; Pérez-Victoria, J.M.
Source: Self-asserted source
José María Pérez-Victoria via Scopus - Elsevier

Celastraceae sesquiterpenes as a new class of modulators that bind specifically to human P-glycoprotein and reverse cellular multidrug resistance

Cancer Research
2004 | Journal article
DOI: 10.1158/0008-5472.CAN-04-1005
EID:

2-s2.0-4944232223
Contributors: Muñoz-Martínez, F.; Lu, P.; Cortés-Selva, F.; Pérez-Victoria, J.M.; Jiménez, I.A.; Ravelo, Á.G.; Sharom, F.J.; Gamarro, F.; Castanys, S.
Source: Self-asserted source
José María Pérez-Victoria via Scopus - Elsevier

Potent competitive inhibition of drug binding to the Saccharomyces cerevisiae ABC exporter Pdr5p by the hydrophobic estradiol-derivative RU49953

Biochimica et Biophysica Acta - Biomembranes
2003 | Journal article
DOI: 10.1016/S0005-2736(03)00193-7
EID:

2-s2.0-0043207603
Contributors: Conseil, G.; Perez-Victoria, J.M.; Renoir, J.M.; Goffeau, A.; Di Pietro, A.
Source: Self-asserted source
José María Pérez-Victoria via Scopus - Elsevier

RU49953: A non-hormonal steroid derivative that potently inhibits P-glycoprotein and reverts cellular multidrug resistance

Cellular and Molecular Life Sciences
2003 | Journal article
DOI: 10.1007/s000180300044
EID:

2-s2.0-0344511821
Contributors: Perez-Victoria, F.J.; Conseil, G.; Munoz-Martinez, F.; Perez-Victoria, J.M.; Dayan, G.; Marsaud, V.; Castanys, S.; Gamarro, F.; Renoir, J.M.; Di Pietro, A.
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José María Pérez-Victoria via Scopus - Elsevier

The overexpression of a new ABC transporter in Leishmania is related to phospholipid trafficking and reduced infectivity

Biochimica et Biophysica Acta - Biomembranes
2003 | Journal article
DOI: 10.1016/S0005-2736(03)00131-7
EID:

2-s2.0-0038730501
Contributors: Parodi-Talice, A.; Araújo, J.M.; Torres, C.; Pérez-Victoria, J.M.; Gamarro, F.; Castanys, S.
Source: Self-asserted source
José María Pérez-Victoria via Scopus - Elsevier

Modulation by flavonoids of cell multidrug resistance mediated by P-glycoprotein and related ABC transporters

Cellular and Molecular Life Sciences
2002 | Journal article
DOI: 10.1007/s00018-002-8424-8
EID:

2-s2.0-18244376403
Contributors: Di Pietro, A.; Conseil, G.; Pérez-Victoria, J.M.; Dayan, G.; Baubichon-Cortay, H.; Trompier, D.; Steinfels, E.; Jault, J.-M.; De Wet, H.; Maitrejean, M. et al.
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José María Pérez-Victoria via Scopus - Elsevier

Multidrug resistance phenotype mediated by the P-glycoprotein-like transporter in Leishmania: A search for reversal agents

Current Drug Targets
2002 | Journal article
DOI: 10.2174/1389450023347588
EID:

2-s2.0-0036018927
Contributors: Pérez-Victoria, J.M.; Di Pietro, A.; Barron, D.; Ravelo, A.G.; Castanys, S.; Gamarro, F.
Source: Self-asserted source
José María Pérez-Victoria via Scopus - Elsevier

ABC transporters in the protozoan parasite Leishmania

International Microbiology
2001 | Journal article
DOI: 10.1007/S10123-001-0031-2
EID:

2-s2.0-0035468512
Contributors: Pérez-Victoria, J.M.; Torres, A.P.-T.C.; Gamarro, F.; Castanys, S.
Source: Self-asserted source
José María Pérez-Victoria via Scopus - Elsevier

Alkyl-lysophospholipid resistance in multidrug-resistant Leishmania tropica and chemosensitization by a novel P-glycoprotein-like transporter modulator

Antimicrobial Agents and Chemotherapy
2001 | Journal article
DOI: 10.1128/AAC.45.9.2468-2474.2001
EID:

2-s2.0-0034863516
Contributors: Pérez-Victoria, J.M.; Pérez-Victoria, F.J.; Parodi-Talice, A.; Jiménez, I.A.; Ravelo, A.G.; Castanys, S.; Gamarro, F.
Source: Self-asserted source
José María Pérez-Victoria via Scopus - Elsevier

Chemosensitization of a multidrug-resistant Leishmania tropica line by new sesquiterpenes from Maytenus magellanica and Maytenus chubutensis

Journal of Medicinal Chemistry
2001 | Journal article
DOI: 10.1021/jm010970c
EID:

2-s2.0-0035924221
Contributors: Kennedy, M.L.; Cortés-Selva, F.; Pérez-Victoria, J.M.; Jiménez, I.A.; González, A.G.; Muñoz, O.M.; Gamarro, F.; Castanys, S.; Ravelo, A.G.
Source: Self-asserted source
José María Pérez-Victoria via Scopus - Elsevier

High-affinity binding of silybin derivatives to the nucleotide-binding domain of a Leishmania tropica P-glycoprotein-like transporter and chemosensitization of a multidrug-resistant parasite to daunomycin

Antimicrobial Agents and Chemotherapy
2001 | Journal article
DOI: 10.1128/AAC.45.2.439-446.2001
EID:

2-s2.0-0035139550
Contributors: Pérez-Victoria, J.M.; Pérez-Victoria, F.J.; Conseil, G.; Maitrejean, M.; Comte, G.; Barron, D.; Di Pietro, A.; Castanys, S.; Gamarro, F.
Source: Self-asserted source
José María Pérez-Victoria via Scopus - Elsevier

Protein kinase C effectors bind to multidrug ABC transporters and inhibit their activity

Biochemistry
2001 | Journal article
DOI: 10.1021/bi002453m
EID:

2-s2.0-0035957082
Contributors: Conseil, G.; Perez-Victoria, J.M.; Jault, J.-M.; Gamarro, F.; Goffeau, A.; Hofmann, J.; Di Pietro, A.
Source: Self-asserted source
José María Pérez-Victoria via Scopus - Elsevier

Correlation between the affinity of flavonoids binding to the cytosolic site of Leishmania tropica multidrug transporter and their efficiency to revert parasite resistance to daunomycin

Biochemistry
1999 | Journal article
DOI: 10.1021/bi982455v
EID:

2-s2.0-0039552151
Contributors: Pérez-Victoria, J.M.; Chiquero, M.J.; Conseil, G.; Dayan, G.; Pietro, A.D.; Barron, D.; Castanys, S.; Gamarro, F.
Source: Self-asserted source
José María Pérez-Victoria via Scopus - Elsevier

New natural sesquiterpenes as modulators of daunomycin resistance in a multidrug-resistant Leishmania tropica line

Journal of Medicinal Chemistry
1999 | Journal article
DOI: 10.1021/jm991066b
EID:

2-s2.0-0043064086
Contributors: Pérez-Victoria, J.M.; Tincusi, B.M.; Jiménez, I.A.; Bazzocchi, I.L.; Gupta, M.P.; Castanys, S.; Gamarro, F.; Ravelo, A.G.
Source: Self-asserted source
José María Pérez-Victoria via Scopus - Elsevier

Altered drug membrane permeability in a multidrug-resistant Leishmania tropica line

Biochemical Pharmacology
1998 | Journal article
DOI: 10.1016/S0006-2952(97)00385-7
EID:

2-s2.0-0344333486
Contributors: Chiquero, M.J.; Pérez-Victoria, J.M.; O'Valle, F.; González-Ros, J.M.; Del Moral, R.G.; Ferragut, J.A.; Castanys, S.; Gamarro, F.
Source: Self-asserted source
José María Pérez-Victoria via Scopus - Elsevier

Involvement of thiol metabolism in resistance to glucantime in Leishmania tropica

Biochemical Pharmacology
1998 | Journal article
DOI: 10.1016/S0006-2952(98)00129-4
EID:

2-s2.0-0345055821
Contributors: Arana, F.E.; Pérez-Victoria, J.M.; Repetto, Y.; Morello, A.; Castanys, S.; Gamarro, F.
Source: Self-asserted source
José María Pérez-Victoria via Scopus - Elsevier
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