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Scopus Author ID: 8555908400

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Czech Republic

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Employment (2)

Charles University: Prague, CZ

2023-06-01 to present | researcher, teacher (First Faculty of Medicine, Department of Biochemistry and Experimental Oncology)
Employment
Source: Self-asserted source
Helena Kupcova Skalnikova

Institute of Animal Physiology and Genetics, Academy of Sciences of the Czech Republic: Libechov, CZ

2003-09-01 to present | researcher (Laboratory of Applied Proteome Analyses)
Employment
Source: Self-asserted source
Helena Kupcova Skalnikova

Works (29)

Fibrillar extracellular matrix produced by pericyte‐like cells facilitates glioma cell dissemination

Brain Pathology
2024-11 | Journal article
DOI: 10.1111/bpa.13265
Contributors: Petr Vymola; Elena Garcia‐Borja; Jakub Cervenka; Eva Balaziova; Barbora Vymolova; Jana Veprkova; Petr Vodicka; Helena Skalnikova; Robert Tomas; David Netuka et al.
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Crossref

Huntingtin Co-Isolates with Small Extracellular Vesicles from Blood Plasma of TgHD and KI-HD Pig Models of Huntington’s Disease and Human Blood Plasma

International Journal of Molecular Sciences
2022-05 | Journal article | Author
DOI: 10.3390/ijms23105598
Contributors: Hanadi Ananbeh; Jaromir Novak; Stefan Juhas; Jana Juhasova; Jiri Klempir; Kristyna Doleckova; Irena Rysankova; Karolína Turnovcová; Jaroslav Hanuš; Hana Hansikova et al.
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Multidisciplinary Digital Publishing Institute

Dextran Sulphate Sodium Acute Colitis Rat Model: A Suitable Tool for Advancing Our Understanding of Immune and Microbial Mechanisms in the Pathogenesis of Inflammatory Bowel Disease

Veterinary Sciences
2022-05-16 | Journal article
DOI: 10.3390/vetsci9050238
Contributors: Petra Adamkova; Petra Hradicka; Helena Kupcova Skalnikova; Veronika Cizkova; Petr Vodicka; Silvia Farkasova Iannaccone; Monika Kassayova; Sona Gancarcikova; Vlasta Demeckova
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Crossref
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Emerging Roles of Exosomes in Huntington’s Disease

International Journal of Molecular Sciences
2021-04-15 | Journal article
DOI: 10.3390/ijms22084085
Contributors: Hanadi Ananbeh; Petr Vodicka; Helena Kupcova Skalnikova
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Crossref
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Proteomic Characterization of Human Neural Stem Cells and Their Secretome During in vitro Differentiation.

Frontiers in cellular neuroscience
2021-01-28 | Journal article
DOI: 10.3389/fncel.2020.612560
PMID: 33584205
PMC: PMC7876319
Source: Self-asserted source
Helena Kupcova Skalnikova

A Comparative Analysis of Multipotent Mesenchymal Stromal Cells derived from Different Sources, with a Focus on Neuroregenerative Potential

Scientific Reports
2020-03-09 | Journal article
DOI: 10.1038/s41598-020-61167-z
Contributors: Yuriy Petrenko; Irena Vackova; Kristyna Kekulova; Milada Chudickova; Zuzana Koci; Karolina Turnovcova; Helena Kupcova Skalnikova; Petr Vodicka; Sarka Kubinova
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Crossref

Spinal subpial delivery of AAV9 enables widespread gene silencing and blocks motoneuron degeneration in ALS

Nature Medicine
2020-01-23 | Journal article
DOI: 10.1038/s41591-019-0674-1
Contributors: Mariana Bravo-Hernandez; Takahiro Tadokoro; Michael R. Navarro; Oleksandr Platoshyn; Yoshiomi Kobayashi; Silvia Marsala; Atsushi Miyanohara; Stefan Juhas; Jana Juhasova; Helena Skalnikova et al.
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Crossref

Melanoma-Bearing Libechov Minipig (MeLiM): The Unique Swine Model of Hereditary Metastatic Melanoma

Genes
2019-11-09 | Journal article
DOI: 10.3390/genes10110915
Contributors: Vratislav Horak; Anna Palanova; Jana Cizkova; Veronika Miltrova; Petr Vodicka; Helena Kupcova Skalnikova
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Crossref
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A Combination of Intrathecal and Intramuscular Application of Human Mesenchymal Stem Cells Partly Reduces the Activation of Necroptosis in the Spinal Cord of SOD1 G93A Rats

STEM CELLS Translational Medicine
2019-06-25 | Journal article
DOI: 10.1002/sctm.18-0223
Contributors: Monika Řehořová; Ingrid Vargová; Serhiy Forostyak; Irena Vacková; Karolína Turnovcová; Helena Kupcová Skalníková; Petr Vodička; Šárka Kubinová; Eva Syková; Pavla Jendelová
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Crossref

Isolation and Characterization of Small Extracellular Vesicles from Porcine Blood Plasma, Cerebrospinal Fluid, and Seminal Plasma

Proteomes
2019-04-25 | Journal article
DOI: 10.3390/proteomes7020017
Contributors: Helena Kupcova Skalnikova; Bozena Bohuslavova; Karolina Turnovcova; Jana Juhasova; Stefan Juhas; Marie Rodinova; Petr Vodicka
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Crossref

AAV5-miHTT Gene Therapy Demonstrates Broad Distribution and Strong Human Mutant Huntingtin Lowering in a Huntington's Disease Minipig Model.

Molecular therapy : the journal of the American Society of Gene Therapy
2018-06 | Journal article
DOI: 10.1016/j.ymthe.2018.06.021
PMID: 30007561
Contributors: Evers MM; Miniarikova J; Juhas S; Vallès A; Bohuslavova B; Juhasova J; Skalnikova HK; Vodicka P; Valekova I; Brouwers C et al.
Source: Self-asserted source
Helena Kupcova Skalnikova via Europe PubMed Central
grade
Preferred source (of 2)‎

Advances in Proteomic Techniques for Cytokine Analysis: Focus on Melanoma Research

International Journal of Molecular Sciences
2017-12 | Journal article
DOI: 10.3390/ijms18122697
Source: check_circle
Multidisciplinary Digital Publishing Institute
grade
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Multiplex immunoassays for quantification of cytokines, growth factors, and other proteins in stem cell communication.

Methods in molecular biology (Clifton, N.J.)
2015-01 | Journal article
DOI: 10.1007/7651_2014_94
PMID: 25063502
Contributors: Valekova I; Skalnikova HK; Jarkovska K; Motlik J; Kovarova H
Source: Self-asserted source
Helena Kupcova Skalnikova via Europe PubMed Central
grade
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Proteomic techniques for characterisation of mesenchymal stem cell secretome.

Biochimie
2013-07 | Journal article
DOI: 10.1016/j.biochi.2013.07.015
PMID: 23880644
Contributors: Kupcova Skalnikova H
Source: Self-asserted source
Helena Kupcova Skalnikova via Europe PubMed Central
grade
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Signaling proteins in spinal parenchyma and dorsal root ganglion in rat with spinal injury-induced spasticity.

Journal of proteomics
2013-07 | Journal article
DOI: 10.1016/j.jprot.2013.06.028
PMID: 23835433
Contributors: Kupcova Skalnikova H; Navarro R; Marsala S; Hrabakova R; Vodicka P; Gadher SJ; Kovarova H; Marsala M
Source: Self-asserted source
Helena Kupcova Skalnikova via Europe PubMed Central
grade
Preferred source (of 2)‎

Development of ovarian hyperstimulation syndrome: interrogation of key proteins and biological processes in human follicular fluid of women undergoing in vitro fertilization.

Molecular human reproduction
2011-06 | Journal article
DOI: 10.1093/molehr/gar047
PMID: 21697218
Contributors: Jarkovska K; Kupcova Skalnikova H; Halada P; Hrabakova R; Moos J; Rezabek K; Gadher SJ; Kovarova H
Source: Self-asserted source
Helena Kupcova Skalnikova via Europe PubMed Central
grade
Preferred source (of 2)‎

Intact protein separation by one- and two-dimensional liquid chromatography for the comparative proteomic separation of partitioned serum or plasma.

Methods in molecular biology (Clifton, N.J.)
2011-01 | Journal article
DOI: 10.1007/978-1-61779-068-3_2
PMID: 21468939
Contributors: Sheng S; Skalnikova H; Meng A; Tra J; Fu Q; Everett A; Van Eyk J
Source: Self-asserted source
Helena Kupcova Skalnikova via Europe PubMed Central
grade
Preferred source (of 2)‎

Mapping of the secretome of primary isolates of mammalian cells, stem cells and derived cell lines.

Proteomics
2011-01 | Journal article
DOI: 10.1002/pmic.201000402
PMID: 21241017
Contributors: Skalnikova H; Motlik J; Gadher SJ; Kovarova H
Source: Self-asserted source
Helena Kupcova Skalnikova via Europe PubMed Central
grade
Preferred source (of 2)‎

Cancer drug-resistance and a look at specific proteins: Rho GDP-dissociation inhibitor 2, Y-box binding protein 1, and HSP70/90 organizing protein in proteomics clinical application.

Journal of proteome research
2010-12 | Journal article
DOI: 10.1021/pr100468w
PMID: 21067243
Contributors: Skalnikova H; Martinkova J; Hrabakova R; Halada P; Dziechciarkova M; Hajduch M; Gadher SJ; Hammar A; Enetoft D; Ekefjard A et al.
Source: Self-asserted source
Helena Kupcova Skalnikova via Europe PubMed Central
grade
Preferred source (of 2)‎

Cyclin-Dependent Kinase Inhibitors and Cancer: Usefulness of Proteomic Approaches in Assessment of the Molecular Mechanisms and Efficacy of Novel Therapeutics

Clinical Proteomics: From Diagnosis to Therapy
2008 | Book
Part of DOI: 10.1002/9783527622153.ch13
EID:

2-s2.0-66749118093
Contributors: Hajduch, M.; Skalnikova, H.; Halada, P.; Vydra, D.; Dzubak, P.; Dziechciarkova, M.; Stmad, M.; Radioch, D.; Gadher, S.J.; Kovarova, H.
Source: Self-asserted source
Helena Kupcova Skalnikova via Scopus - Elsevier

Protein signaling pathways in differentiation of neural stem cells.

Proteomics
2008-11 | Journal article
DOI: 10.1002/pmic.200800096
PMID: 18837464
Contributors: Skalnikova H; Vodicka P; Pelech S; Motlik J; Gadher SJ; Kovarova H
Source: Self-asserted source
Helena Kupcova Skalnikova via Europe PubMed Central
grade
Preferred source (of 2)‎

Proteomics of neural stem cells.

Expert review of proteomics
2008-04 | Journal article
DOI: 10.1586/14789450.5.2.175
PMID: 18466050
Contributors: Skalnikova H; Vodicka P; Gadher SJ; Kovarova H
Source: Self-asserted source
Helena Kupcova Skalnikova via Europe PubMed Central
grade
Preferred source (of 2)‎

Relative quantitation of proteins fractionated by the ProteomeLab PF 2D system using isobaric tags for relative and absolute quantitation (iTRAQ).

Analytical and bioanalytical chemistry
2007-08 | Journal article
DOI: 10.1007/s00216-007-1547-x
PMID: 17724578
Contributors: Skalnikova H; Rehulka P; Chmelik J; Martinkova J; Zilvarova M; Gadher SJ; Kovarova H
Source: Self-asserted source
Helena Kupcova Skalnikova via Europe PubMed Central
grade
Preferred source (of 2)‎

A proteomic approach to studying the differentiation of neural stem cells.

Proteomics
2007-06 | Journal article
DOI: 10.1002/pmic.200600867
PMID: 17474145
Contributors: Skalnikova H; Halada P; Vodicka P; Motlik J; Rehulka P; Hørning O; Chmelik J; Nørregaard Jensen O; Kovarova H
Source: Self-asserted source
Helena Kupcova Skalnikova via Europe PubMed Central
grade
Preferred source (of 2)‎

The characterization of stem cell proteomes

Current Opinion in Molecular Therapeutics
2006 | Journal article
EID:

2-s2.0-33744927186
Contributors: Vodicka, P.; Skalnikova, H.; Kovarova, H.
Source: Self-asserted source
Helena Kupcova Skalnikova via Scopus - Elsevier

The characterization of stem cell proteomes.

Current opinion in molecular therapeutics
2006-06 | Journal article
PMID: 16774043
Contributors: Vodicka P; Skalnikova H; Kovarova H
Source: Self-asserted source
Helena Kupcova Skalnikova via Europe PubMed Central

A system based on principle of two-dimensional liquid chromatography of proteins as an alternative to two-dimensional electrophoresis,Systém pracující na principu dvojrozmě rné kapalinové chromatografie proteinů jako alternativa k dvojrozměrné gelové elektroforéze

Chemicke Listy
2005 | Journal article
EID:

2-s2.0-31544480072
Contributors: Skalníková, H.; Kovářová, H.; Moos, J.; Filová, V.; Halada, P.
Source: Self-asserted source
Helena Kupcova Skalnikova via Scopus - Elsevier

Protein fingerprints of anti-cancer effects of cyclin-dependent kinase inhibition: identification of candidate biomarkers using 2-D liquid phase separation coupled to mass spectrometry.

Technology in cancer research & treatment
2005-08 | Journal article
DOI: 10.1177/153303460500400412
PMID: 16029063
Contributors: Skalnikova H; Halada P; Dzubak P; Hajduch M; Kovarova H
Source: Self-asserted source
Helena Kupcova Skalnikova via Europe PubMed Central
grade
Preferred source (of 2)‎

Cost-effective genotyping of human MBL2 gene mutations using multiplex PCR.

Journal of immunological methods
2004-11 | Journal article
DOI: 10.1016/j.jim.2004.10.007
PMID: 15627619
Contributors: Skalníková H; Freiberger T; Chumchalová J; Grombiríková H; Sedivá A
Source: Self-asserted source
Helena Kupcova Skalnikova via Europe PubMed Central
grade
Preferred source (of 2)‎

Peer review (1 review for 1 publication/grant)

Review activity for Communications biology. (1)
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