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Employment (2)

Salk Institute for Biological Studies: La Jolla, US

2021-08-01 to present | Postdoctoral Fellow (Laboratory of Genetics - Lyumkis)
Employment
Source: Self-asserted source
Tim Strutzenberg

The Scripps Research Institute: Jupiter, FL, US

2015-08-01 to 2021-05-01 | Graduate Research Fellow (Molecular Medicine)
Employment
Source: Self-asserted source
Tim Strutzenberg

Education and qualifications (3)

The Scripps Research Insitute: Jupiter, FL, US

2015-08-01 to present | Ph.D. Chemical and Biological Sciences (Molecular Medicine)
Education
Source: Self-asserted source
Tim Strutzenberg

University of Iowa: Iowa City, IA, US

2011-08-27 to 2015-05-23 | BA Chemistry (Chemistry)
Education
Source: Self-asserted source
Tim Strutzenberg

University of Iowa: Iowa City, IA, US

2011-08-27 to 2015-05-23 | BS Biochemsitry (Chemistry)
Education
Source: Self-asserted source
Tim Strutzenberg

Professional activities (1)

American Society for Mass Spectrometry: Santa Fe, New Mexico, US

2017-05-25 to present
Membership
Source: Self-asserted source
Tim Strutzenberg

Funding (2)

Interrogating the Structural Basis of Nuclear Receptor Activation on Chromatin

2022-09-16 to 2025-09-15 | Grant
National Institute of General Medical Sciences (Bethesda, US)
URL: https://app.dimensions.ai/details/grant/grant.12984823
GRANT_NUMBER: F32GM148049
Source: Self-asserted source
Tim Strutzenberg via DimensionsWizard

Determining the structural basis for ligand-mediated ROR? activation

2017-11-15 to 2019-11-14 | Grant
National Institute of General Medical Sciences (Bethesda, US)
URL: https://app.dimensions.ai/details/grant/grant.7171108
GRANT_NUMBER: F31GM126842
Source: Self-asserted source
Tim Strutzenberg via DimensionsWizard

Works (18)

Nucleosome Engagement Regulates RORγt Structure and Dynamics

2025-03-12 | Preprint
DOI: 10.1101/2025.03.10.642251
Contributors: Timothy S. Strutzenberg; Matthew D. Mann; Xiandu Li; Hyejeong Shin; Jordan Kelsey; Sriram Aiyer; Jingting Yu; Gennavieve Gray; Zeyuan Zhang; Zelin Shan et al.
Source: check_circle
Crossref

Mechanisms of HIV-1 integrase resistance to dolutegravir and potent inhibition of drug-resistant variants

Science Advances
2023-07-21 | Journal article
DOI: 10.1126/sciadv.adg5953
Contributors: Min Li; Dario Oliveira Passos; Zelin Shan; Steven J. Smith; Qinfang Sun; Avik Biswas; Indrani Choudhuri; Timothy S. Strutzenberg; Allan Haldane; Nanjie Deng et al.
Source: check_circle
Crossref

Mechanisms of HIV-1 Integrase Resistance to Dolutegravir and Potent Inhibition of Drug Resistant Variants

2022-12-05 | Preprint
DOI: 10.1101/2022.12.04.519057
Contributors: Min Li; Dario Oliveira Passos; Zelin Shan; Steven J. Smith; Qinfang Sun; Avik Biswas; Indrani Choudhuri; Timothy S. Strutzenberg; Allan Haldane; Nanjie Deng et al.
Source: check_circle
Crossref

Cryo-EM structure of human GPR158 receptor coupled to the RGS7-Gβ5 signaling complex

Science
2022-01-07 | Journal article
DOI: 10.1126/science.abl4732
Contributors: Dipak N. Patil; Shikha Singh; Thibaut Laboute; Timothy S. Strutzenberg; Xingyu Qiu; Di Wu; Scott J. Novick; Carol V. Robinson; Patrick R. Griffin; John F. Hunt et al.
Source: check_circle
Crossref

One-step construction of circularized nanodiscs using SpyCatcher-SpyTag

Nature Communications
2021-09-14 | Journal article
DOI: 10.1038/s41467-021-25737-7
Contributors: Shanwen Zhang; Qian Ren; Scott J. Novick; Timothy S. Strutzenberg; Patrick R. Griffin; Huan Bao
Source: check_circle
Crossref

Structure of an AMPK complex in an inactive, ATP-bound state

Science
2021-07-23 | Journal article
DOI: 10.1126/science.abe7565
Contributors: Yan Yan; Somnath Mukherjee; Kaleeckal G. Harikumar; Timothy S. Strutzenberg; X. Edward Zhou; Kelly Suino-Powell; Ting-Hai Xu; Ryan D. Sheldon; Jared Lamp; Joseph S. Brunzelle et al.
Source: check_circle
Crossref

Conformational Changes of RORγ During Response Element Recognition and Coregulator Engagement

2021-05-26 | Other
DOI: 10.1101/2021.05.25.445650
Contributors: Timothy S. Strutzenberg; Scott J. Novick; Ruben D. Garcia-Ordonez; Christelle Doebelin; Yuanjun He; Mi Ra Chang; Theodore M. Kamenecka; Patrick R. Griffin
Source: check_circle
Crossref

Structural basis for heme-dependent NCoR binding to the transcriptional repressor REV-ERBβ

Science Advances
2021-01-29 | Journal article
DOI: 10.1126/sciadv.abc6479
Contributors: Sarah A. Mosure; Timothy S. Strutzenberg; Jinsai Shang; Paola Munoz-Tello; Laura A. Solt; Patrick R. Griffin; Douglas J. Kojetin
Source: check_circle
Crossref

HDX-MS reveals structural determinants for RORγ hyperactivation by synthetic agonists

eLife
2019 | Journal article
DOI: 10.7554/eLife.47172
Source: Self-asserted source
Tim Strutzenberg
grade
Preferred source (of 2)‎

Recommendations for performing, interpreting and reporting hydrogen deuterium exchange mass spectrometry (HDX-MS) experiments

Nature methods
2019 | Journal article
DOI: 10.1038/s41592-019-0459-y
Source: Self-asserted source
Tim Strutzenberg

Unique Polypharmacology Nuclear Receptor Modulator Blocks Inflammatory Signaling Pathways

ACS chemical biology
2019 | Journal article
DOI: 10.1021/acschembio.9b00236
Source: Self-asserted source
Tim Strutzenberg

Correction: HDX-MS reveals structural determinants for RORγ hyperactivation by synthetic agonists

eLife
2019-10-18 | Journal article
DOI: 10.7554/eLife.52847
Contributors: Timothy S Strutzenberg; Ruben D Garcia-Ordonez; Scott J Novick; HaJeung Park; Mi Ra Chang; Christelle Doebellin; Yuanjun He; Rémi Patouret; Theodore M Kamenecka; Patrick R Griffin
Source: check_circle
Crossref

Bacterial versus human thymidylate synthase: Kinetics and functionality

PloS one
2018 | Journal article
DOI: 10.1371/journal.pone.0196506
Source: Self-asserted source
Tim Strutzenberg

Discovery of Hydrolysis-Resistant Isoindoline N-Acyl Amino Acid Analogues that Stimulate Mitochondrial Respiration

Journal of medicinal chemistry
2018 | Journal article
DOI: 10.1021/acs.jmedchem.8b00029
Source: Self-asserted source
Tim Strutzenberg

Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors

Cell
2018 | Journal article
DOI: 10.1016/j.cell.2018.10.025
Source: Self-asserted source
Tim Strutzenberg

Structural Basis for the RNA-Guided Ribonuclease Activity of CRISPR-Cas13d

Cell
2018 | Journal article
DOI: 10.1016/j.cell.2018.09.001
Source: Self-asserted source
Tim Strutzenberg

Activation of Two Sequential H-transfers in the Thymidylate Synthase Catalyzed Reaction

ACS catalysis
2015 | Journal article
DOI: 10.1021/acscatal.5b01332
Source: Self-asserted source
Tim Strutzenberg

Concerted versus stepwise mechanism in thymidylate synthase

Journal of the American Chemical Society
2014 | Journal article
DOI: 10.1021/ja504341g
Source: Self-asserted source
Tim Strutzenberg
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