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Scopus Author ID: 55882698900

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Employment (5)

University of Exeter: Exeter, GB

2022-08-03 to present | Honorary Clinical Research Fellow (Faculty of Health and Life Sciences)
Employment
Source: Self-asserted source
Alice Hughes

Royal Devon and Exeter Hospital: Exeter, GB

2022-08-03 to present | Doctor
Employment
Source: Self-asserted source
Alice Hughes

University of Exeter: Exeter, Devon, GB

2019-08-07 to 2022-08-02 | Clinical Research Fellow (Institute of Biomedical and Clinical Sciences)
Employment
Source: Self-asserted source
Alice Hughes

Cambridge University Hospitals NHS Foundation Trust: Cambridge, Cambridgeshire, GB

2017-08 to 2019-08
Employment
Source: Self-asserted source
Alice Hughes

Royal Devon and Exeter Hospital: Exeter, Devon, GB

2015-07 to 2017-07 | Academic Foundation Doctor
Employment
Source: Self-asserted source
Alice Hughes

Education and qualifications (4)

University of Exeter: Exeter, GB

2019-08 to 2022-10 | PhD in Medical Sciences
Qualification
Source: Self-asserted source
Alice Hughes

University of Exeter: Exeter, Devon, GB

2016-09 to 2018-10 | MSc Genomic Medicine
Qualification
Source: Self-asserted source
Alice Hughes

University of Exeter: Exeter, Devon, GB

2009-09 to 2015-07 | Bachelor of Medicine, Bachelor of Surgery
Education
Source: Self-asserted source
Alice Hughes

Imperial College London: London, London, GB

2013-10 to 2014-06 | BSc Reproductive and Developmental Sciences
Education
Source: Self-asserted source
Alice Hughes

Funding (1)

Investigating the importance of fetal insulin in birth weight and early postnatal growth

Award
Wellcome Trust (Bristol, GB)
Source: Self-asserted source
Alice Hughes

Works (29)

Nausea and vomiting in pregnancy linked to hormone from fetus.

Nature
2024-01 | Journal article
DOI: 10.1038/d41586-023-03940-4
PMID: 38093044
Contributors: Hughes AE; Freathy RM
Source: Self-asserted source
Alice Hughes via Europe PubMed Central

Precision prognostics for cardiovascular disease in Type 2 diabetes: a systematic review and meta-analysis.

Communications medicine
2024-01 | Journal article
DOI: 10.1038/s43856-023-00429-z
PMID: 38253823
PMC: PMC10803333
Contributors: Ahmad A; Lim LL; Morieri ML; Tam CH; Cheng F; Chikowore T; Dudenhöffer-Pfeifer M; Fitipaldi H; Huang C; Kanbour S et al.
Source: Self-asserted source
Alice Hughes via Europe PubMed Central

Precision stratification of prognostic risk factors associated with outcomes in gestational diabetes mellitus: a systematic review.

Communications medicine
2024-01 | Journal article
DOI: 10.1038/s43856-023-00427-1
PMID: 38216688
PMC: PMC10786838
Contributors: Semnani-Azad Z; Gaillard R; Hughes AE; Boyle KE; Tobias DK; ADA/EASD PMDI; Perng W
Source: Self-asserted source
Alice Hughes via Europe PubMed Central

Refining the diagnosis of gestational diabetes mellitus: a systematic review and meta-analysis.

Communications medicine
2023-12 | Journal article
DOI: 10.1038/s43856-023-00393-8
PMID: 38110524
PMC: PMC10728189
Contributors: Francis EC; Powe CE; Lowe WL; White SL; Scholtens DM; Yang J; Zhu Y; Zhang C; Hivert MF; Kwak SH et al.
Source: Self-asserted source
Alice Hughes via Europe PubMed Central

Disease-modifying therapies and features linked to treatment response in type 1 diabetes prevention: a systematic review.

Communications medicine
2023-10 | Journal article
DOI: 10.1038/s43856-023-00357-y
PMID: 37794169
PMC: PMC10550983
Contributors: Felton JL; Griffin KJ; Oram RA; Speake C; Long SA; Onengut-Gumuscu S; Rich SS; Monaco GSF; Evans-Molina C; DiMeglio LA et al.
Source: Self-asserted source
Alice Hughes via Europe PubMed Central

Genotype-stratified treatment for monogenic insulin resistance: a systematic review.

Communications medicine
2023-10 | Journal article
DOI: 10.1038/s43856-023-00368-9
PMID: 37794082
PMC: PMC10550936
Contributors: Semple RK; Patel KA; Auh S; ADA/EASD PMDI; Brown RJ
Source: Self-asserted source
Alice Hughes via Europe PubMed Central

Impact of individual and environmental factors on dietary or lifestyle interventions to prevent type 2 diabetes development: a systematic review.

Communications medicine
2023-10 | Journal article
DOI: 10.1038/s43856-023-00363-0
PMID: 37794109
PMC: PMC10551013
Contributors: Bodhini D; Morton RW; Santhakumar V; Nakabuye M; Pomares-Millan H; Clemmensen C; Fitzpatrick SL; Guasch-Ferre M; Pankow JS; Ried-Larsen M et al.
Source: Self-asserted source
Alice Hughes via Europe PubMed Central

Participant characteristics in the prevention of gestational diabetes as evidence for precision medicine: a systematic review and meta-analysis.

Communications medicine
2023-10 | Journal article
DOI: 10.1038/s43856-023-00366-x
PMID: 37794119
PMC: PMC10551015
Contributors: Lim S; Takele WW; Vesco KK; Redman LM; Hannah W; Bonham MP; Chen M; Chivers SC; Fawcett AJ; Grieger JA et al.
Source: Self-asserted source
Alice Hughes via Europe PubMed Central

Precision gestational diabetes treatment: a systematic review and meta-analyses.

Communications medicine
2023-10 | Journal article
DOI: 10.1038/s43856-023-00371-0
PMID: 37794196
PMC: PMC10550921
Contributors: Benham JL; Gingras V; McLennan NM; Most J; Yamamoto JM; Aiken CE; Ozanne SE; Reynolds RM; ADA/EASD PMDI
Source: Self-asserted source
Alice Hughes via Europe PubMed Central

Precision subclassification of type 2 diabetes: a systematic review.

Communications medicine
2023-10 | Journal article
DOI: 10.1038/s43856-023-00360-3
PMID: 37798471
PMC: PMC10556101
Contributors: Misra S; Wagner R; Ozkan B; Schön M; Sevilla-Gonzalez M; Prystupa K; Wang CC; Kreienkamp RJ; Cromer SJ; Rooney MR et al.
Source: Self-asserted source
Alice Hughes via Europe PubMed Central

Second international consensus report on gaps and opportunities for the clinical translation of precision diabetes medicine.

Nature medicine
2023-10 | Journal article
DOI: 10.1038/s41591-023-02502-5
PMID: 37794253
Contributors: Tobias DK; Merino J; Ahmad A; Aiken C; Benham JL; Bodhini D; Clark AL; Colclough K; Corcoy R; Cromer SJ et al.
Source: Self-asserted source
Alice Hughes via Europe PubMed Central

The use of precision diagnostics for monogenic diabetes: a systematic review and expert opinion.

Communications medicine
2023-10 | Journal article
DOI: 10.1038/s43856-023-00369-8
PMID: 37794142
PMC: PMC10550998
Contributors: Murphy R; Colclough K; Pollin TI; Ikle JM; Svalastoga P; Maloney KA; Saint-Martin C; Molnes J; ADA/EASD PMDI; Misra S et al.
Source: Self-asserted source
Alice Hughes via Europe PubMed Central

Treatment effect heterogeneity following type 2 diabetes treatment with GLP1-receptor agonists and SGLT2-inhibitors: a systematic review.

Communications medicine
2023-10 | Journal article
DOI: 10.1038/s43856-023-00359-w
PMID: 37794166
PMC: PMC10551026
Contributors: Young KG; McInnes EH; Massey RJ; Kahkoska AR; Pilla SJ; Raghavan S; Stanislawski MA; Tobias DK; McGovern AP; Dawed AY et al.
Source: Self-asserted source
Alice Hughes via Europe PubMed Central

Utility and precision evidence of technology in the treatment of type 1 diabetes: a systematic review.

Communications medicine
2023-10 | Journal article
DOI: 10.1038/s43856-023-00358-x
PMID: 37794113
PMC: PMC10550996
Contributors: Jacobsen LM; Sherr JL; Considine E; Chen A; Peeling SM; Hulsmans M; Charleer S; Urazbayeva M; Tosur M; Alamarie S et al.
Source: Self-asserted source
Alice Hughes via Europe PubMed Central

Bringing precision medicine to the management of pregnancy in women with glucokinase-MODY: a study of diagnostic accuracy and feasibility of non-invasive prenatal testing.

Diabetologia
2023-08 | Journal article
DOI: 10.1007/s00125-023-05982-9
PMID: 37653058
PMC: PMC10542291
Contributors: Hughes AE; Houghton JAL; Bunce B; Chakera AJ; Spyer G; Shepherd MH; Flanagan SE; Hattersley AT
Source: Self-asserted source
Alice Hughes via Europe PubMed Central

Monogenic disease analysis establishes that fetal insulin accounts for half of human fetal growth.

The Journal of clinical investigation
2023-03-15 | Journal article
DOI: 10.1172/jci165402
PMID: 36808723
PMC: PMC10014100
Contributors: Hughes AE; Elisa De Franco; Rachel Freathy; Sarah Flanagan; Andrew Hattersley; Hattersley AT
Source: Self-asserted source
Alice Hughes

Assessing whether genetic scores explain extra variation in birthweight, when added to clinical and anthropometric measures.

BMC pediatrics
2022-08-25 | Journal article
DOI: 10.1186/s12887-022-03554-1
PMID: 36008798
PMC: PMC9414111
Contributors: Haulder M; Hughes AE; Beaumont RN; Knight BA; Hattersley AT; Shields BM; Rachel Freathy
Source: Self-asserted source
Alice Hughes

Association of birthweight and penetrance of diabetes in individuals with HNF4A-MODY: a cohort study.

Diabetologia
2021-10-07 | Journal article | Author
DOI: 10.1007/s00125-021-05581-6
PMID: 34618178
PMC: PMC8660751
Contributors: Jonathan Locke; Petra Dusatkova; Kevin Colclough; Alice Hughes; John Dennis; Beverley Shields; Sarah Flanagan; Maggie Shepherd; Emma Dempster; Andrew Hattersley et al.
Source: Self-asserted source
Alice Hughes

Identification of GCK-maturity-onset diabetes of the young in cases of neonatal hyperglycemia: A case series and review of clinical features.

Pediatric diabetes
2021-06-10 | Journal article | Author
DOI: 10.1111/pedi.13239
PMID: 34085361
PMC: PMC7611537
Contributors: Alice Hughes; De Franco E; Globa E; Zelinska N; Hilgard D; Sifianou P; Hattersley AT; Sarah Flanagan
Source: Self-asserted source
Alice Hughes

All thresholds of maternal hyperglycaemia from the WHO 2013 criteria for gestational diabetes identify women with a higher genetic risk for type 2 diabetes [version 3; peer review: 2 approved, 1 approved with reservations]

2021-03-23 | Journal article
DOI: 10.12688/wellcomeopenres.16097.3
Part of ISSN: 2398-502X
Contributors: Alice E. Hughes; M. Geoffrey Hayes; Aoife M. Egan; Kashyap A. Patel; Denise M. Scholtens; Lynn P. Lowe; William L. Lowe Jr; Fidelma P. Dunne; Andrew T. Hattersley; Rachel M. Freathy
Source: check_circle
Wellcome Open Research

Two decades since the fetal insulin hypothesis: what have we learned from genetics?

Diabetologia
2021-02 | Journal article
DOI: 10.1007/s00125-021-05386-7
PMID: 33569631
PMC: PMC7940336
Contributors: Hughes AE; Hattersley AT; Flanagan SE; Freathy RM
Source: Self-asserted source
Alice Hughes via Europe PubMed Central

A lower maternal cortisol-to-cortisone ratio precedes clinical diagnosis of preterm and term preeclampsia by many weeks

Journal of Clinical Endocrinology and Metabolism
2019 | Journal article
DOI: 10.1210/jc.2018-02312
EID:

2-s2.0-85065596590
Contributors: Jayasuriya, N.A.; Hughes, A.E.; Sovio, U.; Cook, E.; Stephen Charnock-Jones, D.; Smith, G.C.S.
Source: Self-asserted source
Alice Hughes via Scopus - Elsevier

The association between first trimester AFP to PAPP-A ratio and placentally-related adverse pregnancy outcome

Placenta
2019 | Journal article
DOI: 10.1016/j.placenta.2019.04.005
EID:

2-s2.0-85064936582
Contributors: Hughes, A.E.; Sovio, U.; Gaccioli, F.; Cook, E.; Charnock-Jones, D.S.; Smith, G.C.S.
Source: Self-asserted source
Alice Hughes via Scopus - Elsevier

Acute colonic pseudo‐obstruction after caesarean section: a review and recommended management algorithm

The Obstetrician & Gynaecologist
2019-07-25 | Journal article
DOI: 10.1111/tog.12602
Part of ISSN: 1467-2561
Part of ISSN: 1744-4667
Source: Self-asserted source
Alice Hughes

Women with isolated fasting hyperglycemia in pregnancy are at a higher genetic risk for type 2 diabetes

bioRxiv
2019-06-13 | Journal article
DOI: 10.1101/671057
Source: Self-asserted source
Alice Hughes

Fetal genotype and maternal glucose have independent and additive effects on birth weight

Diabetes
2018 | Journal article
DOI: 10.2337/db17-1188
EID:

2-s2.0-85046013181
Contributors: Hughes, A.E.; Nodzenski, M.; Beaumont, R.N.; Talbot, O.; Shields, B.M.; Scholtens, D.M.; Knight, B.A.; >William Lowe, W.L.L.; Hattersley, A.T.; Freathy, R.M.
Source: Self-asserted source
Alice Hughes via Scopus - Elsevier

Quality of placental RNA: Effects of explant size and culture duration

Placenta
2016-10 | Journal article
DOI: 10.1016/j.placenta.2016.08.083
Part of ISSN: 0143-4004
Contributors: O. Brew; E. Nikolopoulou; A. Hughes; M. Christian; Y. Lee; O. Oduwole; M.H.F. Sullivan; A. Woodman
Source: Self-asserted source
Alice Hughes via Crossref Metadata Search

Late preterm birth is associated with short-term morbidity but not with adverse neurodevelopmental and physical outcomes at 1 year

Acta Obstetricia et Gynecologica Scandinavica
2014 | Journal article
DOI: 10.1111/aogs.12258
EID:

2-s2.0-84890571119
Contributors: Hughes, A.; Greisen, G.; Arce, J.-C.; Thornton, S.
Source: Self-asserted source
Alice Hughes via Scopus - Elsevier

Recent advances in the prevention and treatment of preterm labour: Oxytocin antagonists and the silicone (Arabin) pessary

Fetal and Maternal Medicine Review
2014 | Journal article
DOI: 10.1017/S0965539515000017
EID:

2-s2.0-84925013287
Contributors: Kay, O.; Hughes, A.; Saade, G.; Bennett, P.; Terzidou, V.; Thornton, S.
Source: Self-asserted source
Alice Hughes via Scopus - Elsevier
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