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Works (16)

Knock-Out of IKKepsilon Ameliorates Atherosclerosis and Fatty Liver Disease by Alterations of Lipid Metabolism in the PCSK9 Model in Mice

International Journal of Molecular Sciences
2024-10 | Journal article | Author
DOI: 10.3390/ijms251910721
Contributors: Ulrike Weiss; Eleonora Mungo; Michelle Haß; Denis Benning; Robert Gurke; Lisa Hahnefeld; Erika Dorochow; Jessica Schlaudraff; Tobias Schmid; Silvia Kuntschar et al.
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Multidisciplinary Digital Publishing Institute

Resolving the heteromeric composition and macromolecular environment of TRPC channels in the brain.

Cell calcium
2023-02-26 | Journal article
DOI: 10.1016/j.ceca.2023.102714
PMID: 36921407
Contributors: Freichel M; Tsvilovskyy V; Philippaert K
Source: Self-asserted source
Marc Freichel

Efficient single copy integration via homology-directed repair (scHDR) by 5'modification of large DNA donor fragments in mice.

Nucleic acids research
2023-02-01 | Journal article | Author
DOI: 10.1093/nar/gkac1150
PMID: 36533445
PMC: PMC10021492
Contributors: Rebekka Medert; Thomas Thumberger; Tavhelidse-Suck T; Hub T; Kellner T; Oguchi Y; Dlugosz S; Zimmermann F; Wittbrodt J; Marc Freichel
Source: Self-asserted source
Marc Freichel

Characterization of Endo-Lysosomal Cation Channels Using Calcium Imaging.

Handbook of experimental pharmacology
2023-01-01 | Journal article
DOI: 10.1007/164_2023_637
PMID: 36894791
Contributors: Wahl-Schott C; Freichel M; Hennis K; Philippaert K; Ottenheijm R; Tsvilovskyy V; Hristo Varbanov
Source: Self-asserted source
Marc Freichel

Reduction in SOCE and Associated Aggregation in Platelets from Mice with Platelet-Specific Deletion of Orai1

Cells
2022-10 | Journal article | Author
DOI: 10.3390/cells11203225
Contributors: Linlin Yang; Roger Ottenheijm; Paul Worley; Marc Freichel; Juan E. Camacho Londoño
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Multidisciplinary Digital Publishing Institute

Deep Metabolic Profiling Assessment of Tissue Extraction Protocols for Three Model Organisms.

Frontiers in chemistry
2022-04-25 | Journal article
DOI: 10.3389/fchem.2022.869732
PMID: 35548679
PMC: PMC9083328
Contributors: Gegner HM; Mechtel N; Heidenreich E; Wirth A; Cortizo FG; Bennewitz K; Fleming T; Andresen C; Freichel M; Teleman AA et al.
Source: Self-asserted source
Marc Freichel

Emergent Temporal Signaling in Human Trabecular Meshwork Cells: Role of TRPV4-TRPM4 Interactions.

Frontiers in immunology
2022-03-31 | Journal article
DOI: 10.3389/fimmu.2022.805076
PMID: 35432302
PMC: PMC9008486
Contributors: Yarishkin O; Phuong TTT; Vazquez-Chona F; Bertrand J; van Battenburg-Sherwood J; Redmon SN; Rudzitis CN; Lakk M; Baumann JM; Freichel M et al.
Source: Self-asserted source
Marc Freichel

Boosting targeted genome editing using the hei-tag.

eLife
2022-03-25 | Journal article | Author
DOI: 10.7554/elife.70558
PMID: 35333175
PMC: PMC9068219
Contributors: Thomas Thumberger; Tinatini Tavhelidse-Suck; Gutierrez-Triana JA; Alex Cornean; Medert R; Welz B; Marc Freichel; Joachim Wittbrodt
Source: Self-asserted source
Marc Freichel

Novel Nongenetic Murine Model of Hyperglycemia and Hyperlipidemia-Associated Aggravated Atherosclerosis.

Frontiers in cardiovascular medicine
2022-03-08 | Journal article
DOI: 10.3389/fcvm.2022.813215
PMID: 35350534
PMC: PMC8957812
Contributors: Gaul S; Shahzad K; Medert R; Gadi I; Mäder C; Schumacher D; Wirth A; Ambreen S; Fatima S; Boeckel JN et al.
Source: Self-asserted source
Marc Freichel

Trophectoderm cell failure leads to peri-implantation lethality in Trpm7-deficient mouse embryos.

Cell reports
2021-10-01 | Journal article
DOI: 10.1016/j.celrep.2021.109851
PMID: 34686339
Contributors: Schütz A; Richter C; Weissgerber P; Tsvilovskyy V; Michael Hesse; Roger Ottenheijm; Zimmermann F; Buchholz S; Medert R; Dlugosz S et al.
Source: Self-asserted source
Marc Freichel

Cardiac Response to β-Adrenergic Stimulation Determined by Pressure-Volume Loop Analysis.

Journal of visualized experiments : JoVE
2021-05-19 | Journal article
DOI: 10.3791/62057
PMID: 34096910
Contributors: Rebekka Medert; Bacmeister L; Segin S; Freichel M; Juan E. Camacho Londoño
Source: Self-asserted source
Marc Freichel

Development of an AAV9-RNAi-mediated silencing strategy to abrogate TRPM4 expression in the adult heart.

Pflugers Archiv : European journal of physiology
2021-02-13 | Journal article
DOI: 10.1007/s00424-021-02521-6
PMID: 33580817
PMC: PMC7940300
Contributors: Rebekka Medert; Jungmann A; Hildebrand S; Busch M; Grimm D; Flockerzi V; Müller OJ; Most P; Schumacher D; Freichel M
Source: Self-asserted source
Marc Freichel

Enhancing mitochondrial activity in neurons protects against neurodegeneration in a mouse model of multiple sclerosis.

eLife
2021-02-10 | Journal article | Author
DOI: 10.7554/elife.61798
PMID: 33565962
PMC: PMC7993994
Contributors: Sina Cathérine Rosenkranz; Artem Shaposhnykov; Träger S; Jan Broder Engler; Maarten E. Witte; Roth V; Vanessa Vieira; Paauw N; Bauer S; Celina Tretter et al.
Source: Self-asserted source
Marc Freichel

Contribution of TRPC Channels in Neuronal Excitotoxicity Associated With Neurodegenerative Disease and Ischemic Stroke.

Frontiers in cell and developmental biology
2021-01-08 | Journal article
DOI: 10.3389/fcell.2020.618663
PMID: 33490083
PMC: PMC7820370
Contributors: Jeon J; Bu F; Sun G; Tian JB; Shun-Ming Ting; Li J; Aronowski J; Birnbaumer L; Freichel M; Zhu MX
Source: Self-asserted source
Marc Freichel

A Global Cndp1-Knock-Out Selectively Increases Renal Carnosine and Anserine Concentrations in an Age- and Gender-Specific Manner in Mice

International Journal of Molecular Sciences
2020-07 | Journal article | Author
DOI: 10.3390/ijms21144887
Contributors: Tim Weigand; Florian Colbatzky; Tilman Pfeffer; Sven F. Garbade; Kristina Klingbeil; Florian Colbatzky; Michael Becker; Johanna Zemva; Ruben Bulkescher; Robin Schürfeld et al.
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Multidisciplinary Digital Publishing Institute

Cardiomyocyte-Specific Deletion of Orai1 Reveals Its Protective Role in Angiotensin-II-Induced Pathological Cardiac Remodeling

Cells
2020-04 | Journal article | Author
DOI: 10.3390/cells9051092
Contributors: Sebastian Segin; Michael Berlin; Christin Richter; Rebekka Medert; Veit Flockerzi; Paul Worley; Marc Freichel; Juan E. Camacho Londoño
Source: check_circle
Multidisciplinary Digital Publishing Institute
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