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Scopus Author ID: 57217168500

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Charles University in Prague, Faculty of Pharmacy in Hradec Kralove: Hradec Kralove, CZ

2016-10-01 to present (Department of Pharmacology and Toxicology)
Employment
Source: Self-asserted source
Alzbeta Stefela

Works (6)

3β-Isoobeticholic acid efficiently activates the farnesoid X receptor (FXR) due to its epimerization to 3α-epimer by hepatic metabolism

Journal of Steroid Biochemistry and Molecular Biology
2020 | Journal article
DOI: 10.1016/j.jsbmb.2020.105702
EID:

2-s2.0-85086573279

Part of ISSN: 18791220 09600760
Contributors: Stefela, A.; Kaspar, M.; Drastik, M.; Holas, O.; Hroch, M.; Smutny, T.; Skoda, J.; Hutníková, M.; Pandey, A.V.; Micuda, S. et al.
Source: Self-asserted source
Alzbeta Stefela via Scopus - Elsevier

Diazepam Promotes Translocation of Human Constitutive Androstane Receptor (CAR) via Direct Interaction with the Ligand-Binding Domain

Cells
2020 | Journal article
DOI: 10.3390/cells9122532
EID:

2-s2.0-85097036019

Part of ISSN: 20734409
Contributors: Skoda, J.; Dusek, J.; Drastik, M.; Stefela, A.; Dohnalova, K.; Chalupsky, K.; Smutny, T.; Micuda, S.; Gerbal-Chaloin, S.; Pavek, P.
Source: Self-asserted source
Alzbeta Stefela via Scopus - Elsevier

The 3ʹ-untranslated region contributes to the pregnane X receptor (PXR) expression down-regulation by PXR ligands and up-regulation by glucocorticoids

Acta Pharmaceutica Sinica B
2020 | Journal article
DOI: 10.1016/j.apsb.2019.09.010
EID:

2-s2.0-85075515573

Part of ISSN: 22113843 22113835
Contributors: Smutny, T.; Dusek, J.; Hyrsova, L.; Nekvindova, J.; Horvatova, A.; Micuda, S.; Gerbal-Chaloin, S.; Pavek, P.
Source: Self-asserted source
Alzbeta Stefela via Scopus - Elsevier

Stilbene compound trans-3,4,5,4´-tetramethoxystilbene, a potential anticancer drug, regulates constitutive androstane receptor (Car) target genes, but does not possess proliferative activity in mouse liver

Toxicology Letters
2019 | Journal article
DOI: 10.1016/j.toxlet.2019.05.024
EID:

2-s2.0-85067666174

Part of ISSN: 18793169 03784274
Contributors: Dusek, J.; Skoda, J.; Holas, O.; Horvatova, A.; Smutny, T.; Linhartova, L.; Hirsova, P.; Kucera, O.; Micuda, S.; Braeuning, A. et al.
Source: Self-asserted source
Alzbeta Stefela via Scopus - Elsevier

Ursodeoxycholyl lysophosphatidylethanolamide negatively regulates TLR-mediated lipopolysaccharide response in human THP-1-derived macrophages

European Journal of Pharmacology
2018 | Journal article
DOI: 10.1016/j.ejphar.2018.02.030
EID:

2-s2.0-85042494432

Part of ISSN: 18790712 00142999
Contributors: Horvatova, A.; Utaipan, T.; Otto, A.-C.; Zhang, Y.; Gan-Schreier, H.; Pavek, P.; Pathil, A.; Stremmel, W.; Chamulitrat, W.
Source: Self-asserted source
Alzbeta Stefela via Scopus - Elsevier

Acetylated deoxycholic (DCA) and cholic (CA) acids are potent ligands of pregnane X (PXR) receptor

Toxicology Letters
2017 | Journal article
DOI: 10.1016/j.toxlet.2016.11.013
EID:

2-s2.0-84999836874

Part of ISSN: 18793169 03784274
Contributors: Carazo, A.; Hyrsova, L.; Dusek, J.; Chodounska, H.; Horvatova, A.; Berka, K.; Bazgier, V.; Gan-Schreier, H.; Chamulitrat, W.; Kudova, E. et al.
Source: Self-asserted source
Alzbeta Stefela via Scopus - Elsevier
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