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Employment (2)

Ústřední vojenská nemocnice - Vojenská fakultní nemocnice Praha: Praha, Praha, CZ

2014-03-01 to present | Head of the department (Infectious Diseases)
Employment
Source: Self-asserted source
Michal Holub

Univerzita Karlova: Praha, CZ

2004-10-01 to 2015-09-30 | Head of the department, docent, professor (Infectious and Tropical Diseases)
Employment
Source: Self-asserted source
Michal Holub

Education and qualifications (4)

Charles University: Prague, CZ

2010-05 to present | Professor of Infectious Diseases
Education
Source: Self-asserted source
Michal Holub

Charles University, First Faculty of Medicine: Prague, CZ

2004-10 to 2010-04 | Habilitation in infectious diseases (docent)
Education
Source: Self-asserted source
Michal Holub

Charles University: Prague, CZ

1995 to 2003 | Ph.D. (Human Physiology and Pathophysiology)
Education
Source: Self-asserted source
Michal Holub

Charles University: Prague, CZ

1982 to 1989 | M.D. (Faculty of Pediatrics)
Education
Source: Self-asserted source
Michal Holub

Funding (3)

Alarmins in the development and diagnostics of septic complications of tissue injury

2015-05 to 2018-12 | Grant
Agentura pro zdravotnický výzkum České republiky (Prague, CZ)
GRANT_NUMBER:

AZV 15-30186A
Source: Self-asserted source
Michal Holub

New biomarkers for early detection of nosocomial infection in intensive care

2010-05 to 2014-08 | Grant
Internal Grant Agency of the Czech Ministry of Health (Prague, CZ)
GRANT_NUMBER:

NT/11390
Source: Self-asserted source
Michal Holub

The development of a comprehensive assessment methodology for the immune preparedness of members of the security and protective services responding to the COVID-19 pandemic

Grant
Ministry of Interior of the Czech Republic (Praha, CZ)
URL: https://starfos.tacr.cz/cs/project/VI04000078?query_code=7tqqaacnrsxa
Part of GRANT_NUMBER:

VI04000078

Source: Self-asserted source
Michal Holub

Works (50 of 112)

Items per page:
Page 1 of 3

Evaluation of Soluble Urokinase Plasminogen Activator Receptor in COVID-19 Patients

Journal of Clinical Medicine
2024-10-23 | Journal article
DOI: 10.3390/jcm13216340
Contributors: Simona Arientová; Kateřina Matúšková; Oldřich Bartoš; Ondřej Beran; Michal Holub
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Multiparametric analysis of the specific immune response against SARS-CoV-2

Infectious Diseases
2024-10-02 | Journal article
DOI: 10.1080/23744235.2024.2358379
Contributors: Lucie Vránová; Ingrid Poláková; Šárka Vaníková; Martina Saláková; Jan Musil; Marie Vaníčková; Ondřej Vencálek; Michal Holub; Miloš Bohoněk; David Řezáč et al.
Source: check_circle
Crossref

Convalescent anti-SARS-CoV-2 plasma for the treatment of patients with COVID-19: a retrospective study RESCOVID-19

Virology Journal
2024-09-30 | Journal article
DOI: 10.1186/s12985-024-02475-y
Part of ISSN: 1743-422X
Contributors: Miloš Bohoněk; Jan Máca; Jiří Sagan; David Řezáč; Viktor Fridrich; Anna Burantová; Dominik Kutáč; Pavel Vabroušek; Jan Kubů; Aleš Chrdle et al.
Source: Self-asserted source
Michal Holub

The role of extracellular vesicle fusion with target cells in triggering systemic inflammation

Nature Communications
2024-02-07 | Journal article | Author
DOI: 10.1038/s41467-024-45125-1
Part of ISSN: 2041-1723
Contributors: Praveen Papareddy; Ines Tapken; Keshia Kroh; Ravi Kiran Varma Bhongir; MD MILLADUR RAHMAN; Maria Baumgarten; Eda Irem Cim; Lilla Györffy; Emanuel Smeds; Ariane Neumann et al.
Source: Self-asserted source
Michal Holub

Identifying biomarkers deciphering sepsis from trauma-induced sterile inflammation and trauma-induced sepsis

Frontiers in Immunology
2024-01-12 | Journal article
DOI: 10.3389/fimmu.2023.1310271
Part of ISSN: 1664-3224
Contributors: Praveen Papareddy; Michael Selle; Nicolas Partouche; Vincent Legros; Benjamin Rieu; Jon Olinder; Cecilia Ryden; Eva Bartakova; Michal Holub; Klaus Jung et al.
Source: Self-asserted source
Michal Holub

Specific immune responses after BNT162b2 mRNA vaccination and COVID-19 infection

Frontiers in Immunology
2023-10-17 | Journal article
DOI: 10.3389/fimmu.2023.1271353
Part of ISSN: 1664-3224
Contributors: Simona Arientová; Kateřina Matúšková; Oldřich Bartoš; Michal Holub; Ondřej Beran
Source: Self-asserted source
Michal Holub

Elevated regulatory T cells after antibiotic treatment of infectious spondylodiscitis as biomarker of recovery?

Immunology letters
2023-04-17 | Journal article
DOI: 10.1016/j.imlet.2023.04.006
PMID: 37075915
Contributors: Arientová S; Beran O; Matúšková K; Stráníková A; Holub M
Source: Self-asserted source
Michal Holub
grade
Preferred source (of 2)‎

Acute phase of COVID-19 is associated with elevated plasmablasts in the blood

Bratislava Medical Journal
2022 | Journal article
DOI: 10.4149/bll_2022_039
Part of ISSN: 1336-0345
Source: Self-asserted source
Michal Holub

Retrospective Analysis Revealed an April Occurrence of Monkeypox in the Czech Republic.

Viruses
2022-08-15 | Journal article
DOI: 10.3390/v14081773
PMID: 36016395
PMC: PMC9412638
Contributors: Martin Chmel; Bartoš O; Kabíčková H; Petr Pajer; Pavla Kubíčková; Novotná I; Bartovská Z; Zlámal M; Burantová A; Holub M et al.
Source: Self-asserted source
Michal Holub

Monkeypox and Herpes Simplex Virus Type 2 Coinfection: Case Report of Perianal Lesions in HIV-Positive Patient.

Sexually transmitted diseases
2022-08-11 | Journal article
DOI: 10.1097/olq.0000000000001694
PMID: 35948285
Contributors: Zlámal M; Bartovská Z; Burantová A; Zákoucká H; Jiřincová H; Chmel M; Holub M
Source: Self-asserted source
Michal Holub

Autoimmunity, cancer and COVID-19 abnormally activate wound healing pathways: critical role of inflammation.

Histochemistry and cell biology
2022-07-22 | Journal article
DOI: 10.1007/s00418-022-02140-x
PMID: 35867145
PMC: PMC9305064
Contributors: Gál P; Brábek J; Holub M; Jakubek M; Šedo A; Lukáš Lacina; Strnadová K; Dubový P; Hornychová H; Ryška A et al.
Source: Self-asserted source
Michal Holub

Decreased quality of care for Staphylococcus aureus bacteremia during the COVID-19 pandemic.

BMC infectious diseases
2022-07-19 | Journal article
DOI: 10.1186/s12879-022-07607-9
PMID: 35854225
PMC: PMC9297622
Contributors: Arientová S; Jícha Z; Beran O; Holub M
Source: Self-asserted source
Michal Holub

Chronic Hepatitis C Virus Infection Modulates the Transcriptional Profiles of CD4+ T Cells

Canadian Journal of Infectious Diseases and Medical Microbiology
2021-03-12 | Journal article
DOI: 10.1155/2021/6689834
Contributors: Michal Holub; Alžběta Stráníková; Ondřej Beran; Simona Arientová; Oldřich Bartoš; Kateřina Kondelková; Stanislav Plíšek; Pavel Chalupa; Aseer Manilal
Source: check_circle
Crossref

Clinical management of Staphylococcus aureus bacteremia.

Casopis lekaru ceskych
2021-01-01 | Journal article
PMID: 34416816
Source: Self-asserted source
Michal Holub

Fatal Neutropenic Colitis and Clostridium Septicum Bacteremia in a Breast Cancer Patient.

Prague medical report
2021-01-01 | Journal article
DOI: 10.14712/23362936.2021.18
PMID: 34606433
Source: Self-asserted source
Michal Holub

Salmonella Paratyphi Infection: Use of Nanopore Sequencing as a Vivid Alternative for the Identification of Invading Bacteria.

Prague medical report
2021-01-01 | Journal article
DOI: 10.14712/23362936.2021.10
PMID: 34137685
Source: Self-asserted source
Michal Holub

Frequent Recurrences of Genital Herpes Are Associated with Enhanced Systemic HSV-Specific T Cell Response

Canadian Journal of Infectious Diseases and Medical Microbiology
2020-01-25 | Journal article
DOI: 10.1155/2020/5640960
Contributors: Michal Holub; Alžběta Stráníková; Pavel Chalupa; Simona Arientová; Kateřina Roubalová; Ondřej Beran
Source: check_circle
Crossref

A case of severe course of COVID-19 treated with experimental therapy.

Casopis lekaru ceskych
2020-01-01 | Journal article
PMID: 33297704
Source: Self-asserted source
Michal Holub

Data from the first wave of Covid-19 from the Central Military Hospital, Prague, Czech Republic.

Epidemiologie, mikrobiologie, imunologie : casopis Spolecnosti pro epidemiologii a mikrobiologii Ceske lekarske spolecnosti J.E. Purkyne
2020-01-01 | Journal article
PMID: 33445940
Source: Self-asserted source
Michal Holub

Pre-exposure prophylaxis, a new approach for HIV prevention: experience from the HIV Center of the Military University Hospital Prague.

Epidemiologie, mikrobiologie, imunologie : casopis Spolecnosti pro epidemiologii a mikrobiologii Ceske lekarske spolecnosti J.E. Purkyne
2020-01-01 | Journal article
PMID: 32326714
Source: Self-asserted source
Michal Holub

Production and use of convalescent plasma in COVID-19 treatment, taking into account the experience in the Central Millitary Hospital Prague.

Casopis lekaru ceskych
2020-01-01 | Journal article
PMID: 33297703
Source: Self-asserted source
Michal Holub

Calprotectin and Calgranulin C as Biomarkers of Pancreatic Tumors: Baseline Levels and Level Changes after Surgery

Mediators of Inflammation
2019-09-09 | Journal article
DOI: 10.1155/2019/6985703
Contributors: Michal Holub; Eva Bartáková; Alžběta Stráníková; Eva Koblihová; Simona Arientová; Marie Blahutová; Jan Máca; Miroslav Ryska
Source: check_circle
Crossref

Antithrombin as a marker of severe acute hepatitis B.

Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology
2019-04-01 | Journal article
DOI: 10.1007/s12664-019-00948-5
PMID: 31090040
Source: Self-asserted source
Michal Holub

A Case of a patient with AIDS and Pneumocystis pneumonia complicated by cytomegalovirus pneumonitis,Případ pacienta s AIDS a pneumocystovou pneumonií komplikovanou cytomegalovirovou pneumonitidou

Klinicka Mikrobiologie a Infekcni Lekarstvi
2018 | Journal article
EID:

2-s2.0-85048720631
Contributors: Bartovská, Z.; Zlámal, M.; Murínová, I.; Tyll, T.; Holub, M.
Source: Self-asserted source
Michal Holub via Scopus - Elsevier

A new definition of sepsis (Sepsis-3)–aims, advantages, and controversies,Nová definice sepse (Sepsis-3): cíle, přednosti a kontroverze

Epidemiologie, Mikrobiologie, Imunologie
2018 | Journal article
EID:

2-s2.0-85046713064
Contributors: Máca, J.; Sklienka, P.; Reimer, P.; Holub, M.
Source: Self-asserted source
Michal Holub via Scopus - Elsevier

Alarmins as biomarkers of gastrointestinal surgical injury – a pilot study

APMIS
2018 | Journal article
DOI: 10.1111/apm.12798
EID:

2-s2.0-85041065598
Contributors: Maca, J.; Holub, M.; Bursa, F.; Ihnat, P.; Reimer, P.; Svagera, Z.; Burda, M.; Sevcik, P.
Source: Self-asserted source
Michal Holub via Scopus - Elsevier

Selected Biomarkers Correlate with the Origin and Severity of Sepsis

Mediators of Inflammation
2018 | Journal article
DOI: 10.1155/2018/7028267
Contributors: Michal Holub; Olga Džupová; Michaela Růžková; Alžběta Stráníková; Eva Bartáková; Jan Máca; Jiří Beneš; Heiko Herwald; Ondřej Beran
Source: check_circle
Crossref

Calprotectin and calgranulin C serum levels in bacterial sepsis.

Diagnostic microbiology and infectious disease
2018-10-17 | Journal article
DOI: 10.1016/j.diagmicrobio.2018.10.006
PMID: 30420210
Source: Self-asserted source
Michal Holub

Bacteremia due to Staphylococcus aureus - the importance of appropriate management.

Epidemiologie, mikrobiologie, imunologie : casopis Spolecnosti pro epidemiologii a mikrobiologii Ceske lekarske spolecnosti J.E. Purkyne
2018-01-01 | Journal article
PMID: 30126286
Source: Self-asserted source
Michal Holub

Case of Early Neurosyphilis with Neurocognitive Impairment,Případ Časné neurosyfilis s neurokognitivní poruchou

Ceska a Slovenska Neurologie a Neurochirurgie
2017 | Journal article
DOI: 10.14735/amcsnn2017717
EID:

2-s2.0-85037658502
Contributors: Holub, M.
Source: Self-asserted source
Michal Holub via Scopus - Elsevier

Alarmins and Clinical Outcomes After Major Abdominal Surgery-A Prospective Study.

Journal of investigative surgery : the official journal of the Academy of Surgical Research
2017-06 | Journal article
DOI: 10.1080/08941939.2016.1231855
PMID: 27689623
Source: Self-asserted source
Michal Holub via Europe PubMed Central
grade
Preferred source (of 2)‎

Past and Present ARDS Mortality Rates: A Systematic Review.

Respiratory care
2017-01 | Journal article
DOI: 10.4187/respcare.04716
PMID: 27803355
Source: Self-asserted source
Michal Holub via Europe PubMed Central
grade
Preferred source (of 2)‎

A case of severe progression of HIV-1 meningoencephalitis and lues secundaria,Pripad zavazneho prubehu HIV-1 meningoencefalitidy a lues secundaria

Ceska a Slovenska Neurologie a Neurochirurgie
2016 | Journal article
EID:

2-s2.0-85007605028
Contributors: Zlámal, M.; Smejkal, P.; Tyll, T.; Havliček, R.; Navrátil, P.; Holub, M.
Source: Self-asserted source
Michal Holub via Scopus - Elsevier

Lemierre's syndrome

International Journal of Infectious Diseases
2016 | Journal article
DOI: 10.1016/j.ijid.2016.05.026
EID:

2-s2.0-84975515748
Contributors: Stefan, M.; Klika, D.; Chrdle, A.; Smejkal, P.; Holub, M.
Source: Self-asserted source
Michal Holub via Scopus - Elsevier

New definitions for sepsis and septic shock - Sepsis-3,Nová definice sepse a septického šoku - Sepsis-3

Klinicka Mikrobiologie a Infekcni Lekarstvi
2016 | Journal article
EID:

2-s2.0-85015447287
Contributors: Holub, M.; Beran, O.
Source: Self-asserted source
Michal Holub via Scopus - Elsevier

Outpatient parenteral antibiotic therapy (OPAT),Ambulantní parenterální antibiotická terapie (OPAT)

Casopis Lekaru Ceskych
2016 | Journal article
EID:

2-s2.0-84974627340
Contributors: Štefan, M.; Holub, M.
Source: Self-asserted source
Michal Holub via Scopus - Elsevier

Effect of antiviral treatment of chronic hepatitis C on the frequency of regulatory T cells, T-cell activation, and serum levels of TGF-beta.

2016-06 | Journal article
DOI: 10.1111/apm.12561
PMID: 27307383
Contributors: Chalupa P; Davidová A; Beran O; Arientová S; Boštík P; Kapla J; Kondělková K; Plíšek S; Holub M
Source: Self-asserted source
Michal Holub via Europe PubMed Central

A case of tuberculous meningitis associated with persistently reduced CD4+ T lymphocyte counts,Případ tuberkulózní meningitidy provázené perzistujícím snížením CD4+ T lymfocytů

Epidemiologie, Mikrobiologie, Imunologie
2015 | Journal article
EID:

2-s2.0-84928558743
Contributors: Holub, M.; Beran, O.; Džupová, O.; Rozsypal, H.
Source: Self-asserted source
Michal Holub via Scopus - Elsevier

Immune response in the pathogenesis of hepatitis C virus infection,Imunitní odpověd'v patogenezi infekce virem hepatitidy C

Epidemiologie, Mikrobiologie, Imunologie
2015 | Journal article
EID:

2-s2.0-84976585892
Contributors: Chalupa, P.; Holub, M.; Davidová, A.; Arientová, S.; Beran, O.
Source: Self-asserted source
Michal Holub via Scopus - Elsevier

Incidence, immunological and clinical characteristics of reactivation of latent Toxoplasma gondii infection in HIV-infected patients

Epidemiology and Infection
2015 | Journal article
DOI: 10.1017/S0950268814001253
EID:

2-s2.0-84921433745
Contributors: Kodym, P.; Malý, M.; Beran, O.; Jilich, D.; Rozsypal, H.; MacHala, L.; Holub, M.
Source: Self-asserted source
Michal Holub via Scopus - Elsevier

The Effect of LatentToxoplasma gondiiInfection on the Immune Response in HIV-Infected Patients

BioMed Research International
2015 | Journal article
DOI: 10.1155/2015/271842
Contributors: Ondrej Beran; Petr Kodym; Marek Maly; Alzbeta Davidova; Gabriela Reinvartova; David Jilich; Michal Holub; Hanus Rozsypal
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Toxic shock syndrome,Syndrom toxick�ho Šoku

Epidemiologie, Mikrobiologie, Imunologie
2015 | Journal article
EID:

2-s2.0-84976558777
Contributors: Tyll, T.; B�lkov�, M.; Revinov�, A.; M�ller, M.; Čurdov�, M.; Zl�mal, M.; Holub, M.
Source: Self-asserted source
Michal Holub via Scopus - Elsevier

Different cytokine production and toll-like receptor expression induced by heat-killed invasive and carrier strains of Neisseria meningitidis

APMIS
2014 | Journal article
DOI: 10.1111/apm.12062
EID:

2-s2.0-84891156292
Contributors: Potmesil, R.; Beran, O.; Musilek, M.; Kriz, P.; Holub, M.
Source: Self-asserted source
Michal Holub via Scopus - Elsevier

Endemic hepatitis e in the Czech Republic

Clinical Infectious Diseases
2014 | Journal article
DOI: 10.1093/cid/cit782
EID:

2-s2.0-84893217961
Contributors: Chalupa, P.; Vasickova, P.; Pavlik, I.; Holub, M.
Source: Self-asserted source
Michal Holub via Scopus - Elsevier

Letter to the editor. NRL/NLCR.

Bratislavské lekárske listy
2014 | Journal article
EID:

2-s2.0-84907242621
Contributors: Holub, M.
Source: Self-asserted source
Michal Holub via Scopus - Elsevier

Targeted mass spectrometry analysis of neutrophil-derived proteins released during sepsis progression

Thrombosis and Haemostasis
2014 | Journal article
DOI: 10.1160/TH14-04-0312
EID:

2-s2.0-84914169130
Contributors: Malmström, E.; Davidova, A.; Mörgelin, M.; Linder, A.; Larsen, M.; Qvortrup, K.; Nordenfelt, P.; Shannon, O.; Dzupova, O.; Holub, M. et al.
Source: Self-asserted source
Michal Holub via Scopus - Elsevier

Difficulties diagnosing progressive multifocal leukoencephalopathy in patients infected with the human immunodeficiency virus - Case reports,Úskalí diagnostiky progresivní multifoká lní leukoencefalopatie u pacientů infikovaných lidským virem imunodeficience - Kazuistiky

Ceska a Slovenska Neurologie a Neurochirurgie
2013 | Journal article
EID:

2-s2.0-84882415718
Contributors: Rozsypal, H.; Jilich, D.; Hubáček, P.; Holub, M.
Source: Self-asserted source
Michal Holub via Scopus - Elsevier

Novinky u sepse - Zpráva z 23. Evropského kongresu klinické mikrobiologie a infekčního lékař ství

Klinicka Mikrobiologie a Infekcni Lekarstvi
2013 | Journal article
EID:

2-s2.0-84881468158
Contributors: Holub, M.
Source: Self-asserted source
Michal Holub via Scopus - Elsevier

Severe eosinophilia in a patient with clostridium colitis and gastric cancer,Závažná eosinofilie u pacienta s klostridiovou kolitidou a karcinomem žaludku

Klinicka Mikrobiologie a Infekcni Lekarstvi
2013 | Journal article
EID:

2-s2.0-84878752570
Contributors: Holub, M.; Arientová, S.; Kořínková, M.; Reisingerová, M.; Marešová, V.
Source: Self-asserted source
Michal Holub via Scopus - Elsevier

Toxic shock syndrome and persistent immune activation in an HIV positive patient

Current HIV Research
2013 | Journal article
DOI: 10.2174/1570162X113119990045
EID:

2-s2.0-84886054627
Contributors: Holub, M.; Arientová, S.; Jilich, D.; Davidová, A.; Beran, O.; Rozsypal, H.
Source: Self-asserted source
Michal Holub via Scopus - Elsevier
Items per page:
Page 1 of 3
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