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Scopus Author ID: 55769951400

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Employment (2)

Toyama Prefectural University: Imizu, JP

2024-04-01 to present | Senior Lecture (Biotechnology)
Employment
Source: Self-asserted source
Hiraku Takada

Kyoto Sangyo University: Kyoto, Kyôto, JP

2021-03-08 to 2024-03-31 | Postdoctoral fellow (Faculty of Life Sciences)
Employment
Source: Self-asserted source
Hiraku Takada

Works (37)

Genomic SELEX Reveals Pervasive Role of the Flagella Master Regulator FlhDC in Carbon Metabolism

International Journal of Molecular Sciences
2023-02 | Journal article | Author
DOI: 10.3390/ijms24043696
Contributors: Hiraku Takada; Kaede Kijima; Akira Ishiguro; Akira Ishihama; Tomohiro Shimada
Source: check_circle
Multidisciplinary Digital Publishing Institute

Structural basis for PoxtA-mediated resistance to phenicol and oxazolidinone antibiotics

Nature communications
2022 | Journal article
DOI: 10.1038/s41467-022-29274-9
EID:

2-s2.0-85127639432

Part of ISSN: 20411723
Contributors: Crowe-McAuliffe, C.; Murina, V.; Turnbull, K.J.; Huch, S.; Kasari, M.; Takada, H.; Nersisyan, L.; Sundsfjord, A.; Hegstad, K.; Atkinson, G.C. et al.
Source: Self-asserted source
Hiraku Takada via Scopus - Elsevier

Synthetic oxepanoprolinamide iboxamycin is highly active against human pathogen Listeria monocytogenes

bioRxiv
2022 | Other
DOI: 10.1101/2022.02.28.482263
EID:

2-s2.0-85126950847

Part of ISSN: 26928205
Contributors: Brodiazhenko, T.; Turnbull, K.J.; Wu, K.J.Y.; Takada, H.; Tresco, B.I.C.; Tenson, T.; Myers, A.G.; Hauryliuk, V.
Source: Self-asserted source
Hiraku Takada via Scopus - Elsevier

(p)ppGpp controls stringent factors by exploiting antagonistic allosteric coupling between catalytic domains

Molecular Cell
2021 | Journal article
DOI: 10.1016/j.molcel.2021.07.026
EID:

2-s2.0-85112792870

Part of ISSN: 10974164 10972765
Contributors: Roghanian, M.; Van Nerom, K.; Takada, H.; Caballero-Montes, J.; Tamman, H.; Kudrin, P.; Talavera, A.; Dzhygyr, I.; Ekström, S.; Atkinson, G.C. et al.
Source: Self-asserted source
Hiraku Takada via Scopus - Elsevier

Nonhydrolysable Analogues of (p)ppGpp and (p)ppApp Alarmone Nucleotides as Novel Molecular Tools

ACS Chemical Biology
2021 | Journal article
DOI: 10.1021/acschembio.1c00398
EID:

2-s2.0-85115092887

Part of ISSN: 15548937 15548929
Contributors: Mojr, V.; Roghanian, M.; Tamman, H.; Do Pham, D.D.; Petrová, M.; Pohl, R.; Takada, H.; Van Nerom, K.; Ainelo, H.; Caballero-Montes, J. et al.
Source: Self-asserted source
Hiraku Takada via Scopus - Elsevier

RelA-SpoT Homolog toxins pyrophosphorylate the CCA end of tRNA to inhibit protein synthesis

Molecular Cell
2021 | Journal article
DOI: 10.1016/j.molcel.2021.06.005
EID:

2-s2.0-85111582311

Part of ISSN: 10974164 10972765
Contributors: Kurata, T.; Brodiazhenko, T.; Alves Oliveira, S.R.; Roghanian, M.; Sakaguchi, Y.; Turnbull, K.J.; Bulvas, O.; Takada, H.; Tamman, H.; Ainelo, A. et al.
Source: Self-asserted source
Hiraku Takada via Scopus - Elsevier

Ribosome association primes the stringent factor Rel for tRNA-dependent locking in the A-site and activation of (p)ppGpp synthesis

Nucleic Acids Research
2021 | Journal article
DOI: 10.1093/nar/gkaa1187
EID:

2-s2.0-85099721919

Part of ISSN: 13624962 03051048
Contributors: Takada, H.; Roghanian, M.; Caballero-Montes, J.; Van Nerom, K.; Jimmy, S.; Kudrin, P.; Trebini, F.; Murayama, R.; Akanuma, G.; Garcia-Pino, A. et al.
Source: Self-asserted source
Hiraku Takada via Scopus - Elsevier

RqcH and RqcP catalyze processive poly-alanine synthesis in a reconstituted ribosome-associated quality control system

Nucleic Acids Research
2021 | Journal article
DOI: 10.1093/nar/gkab589
EID:

2-s2.0-85114355096

Part of ISSN: 13624962 03051048
Contributors: Takada, H.; Crowe-Mcauliffe, C.; Polte, C.; Sidorova, Z.Y.; Murina, V.; Atkinson, G.C.; Konevega, A.L.; Ignatova, Z.; Wilson, D.N.; Hauryliuk, V.
Source: Self-asserted source
Hiraku Takada via Scopus - Elsevier

Structural Basis for Bacterial Ribosome-Associated Quality Control by RqcH and RqcP

Molecular Cell
2021 | Journal article
DOI: 10.1016/j.molcel.2020.11.002
EID:

2-s2.0-85097878793

Part of ISSN: 10974164 10972765
Contributors: Crowe-McAuliffe, C.; Takada, H.; Murina, V.; Polte, C.; Kasvandik, S.; Tenson, T.; Ignatova, Z.; Atkinson, G.C.; Wilson, D.N.; Hauryliuk, V.
Source: Self-asserted source
Hiraku Takada via Scopus - Elsevier

Structural basis for PoxtA-mediated resistance to Phenicol and Oxazolidinone antibiotics

bioRxiv
2021 | Other
DOI: 10.1101/2021.06.18.448924
EID:

2-s2.0-85111642724

Part of ISSN: 26928205
Contributors: Crowe-McAuliffe, C.; Murina, V.; Kasari, M.; Takada, H.; Turnbull, K.J.; Polikanov, Y.S.; Sundsfjord, A.; Hegstad, K.; Atkinson, G.C.; Wilson, D.N. et al.
Source: Self-asserted source
Hiraku Takada via Scopus - Elsevier

Structural basis of ABCF-mediated resistance to pleuromutilin, lincosamide, and streptogramin A antibiotics in Gram-positive pathogens

Nature Communications
2021 | Journal article
DOI: 10.1038/s41467-021-23753-1
EID:

2-s2.0-85107814945

Part of ISSN: 20411723
Contributors: Crowe-McAuliffe, C.; Murina, V.; Turnbull, K.J.; Kasari, M.; Mohamad, M.; Polte, C.; Takada, H.; Vaitkevicius, K.; Johansson, J.; Ignatova, Z. et al.
Source: Self-asserted source
Hiraku Takada via Scopus - Elsevier

A nucleotide-switch mechanism mediates opposing catalytic activities of Rel enzymes

Nature Chemical Biology
2020 | Journal article
DOI: 10.1038/s41589-020-0520-2
EID:

2-s2.0-85084513439

Part of ISSN: 15524469 15524450
Contributors: Tamman, H.; Van Nerom, K.; Takada, H.; Vandenberk, N.; Scholl, D.; Polikanov, Y.; Hofkens, J.; Talavera, A.; Hauryliuk, V.; Hendrix, J. et al.
Source: Self-asserted source
Hiraku Takada via Scopus - Elsevier

A widespread toxin−antitoxin system exploiting growth control via alarmone signaling

Proceedings of the National Academy of Sciences of the United States of America
2020 | Journal article
DOI: 10.1073/pnas.1916617117
EID:

2-s2.0-85084503982

Part of ISSN: 10916490 00278424
Contributors: Jimmy, S.; Saha, C.K.; Kurata, T.; Stavropoulos, C.; Oliveira, S.R.A.; Koh, A.; Cepauskas, A.; Takada, H.; Rejman, D.; Tenson, T. et al.
Source: Self-asserted source
Hiraku Takada via Scopus - Elsevier

Novel (p)ppGpp<sup>0</sup> suppressor mutations reveal an unexpected link between methionine catabolism and GTP synthesis in Bacillus subtilis

Molecular Microbiology
2020 | Journal article
DOI: 10.1111/mmi.14484
EID:

2-s2.0-85086480847

Part of ISSN: 13652958 0950382X
Contributors: Osaka, N.; kanesaki, Y.; Watanabe, M.; Watanabe, S.; Chibazakura, T.; Takada, H.; Yoshikawa, H.; Asai, K.
Source: Self-asserted source
Hiraku Takada via Scopus - Elsevier

Ribosome association primes the stringent factor Rel for recruitment of deacylated tRNA to ribosomal A-site

bioRxiv
2020 | Other
DOI: 10.1101/2020.01.17.910273
EID:

2-s2.0-85094363847

Part of ISSN: 26928205
Contributors: Takada, H.; Roghanian, M.; Caballero-Montes, J.; Van Nerom, K.; Jimmy, S.; Kudrin, P.; Trebini, F.; Murayama, R.; Akanuma, G.; Garcia-Pino, A. et al.
Source: Self-asserted source
Hiraku Takada via Scopus - Elsevier

Ribosome Association Primes the Stringent Factor Rel for Recruitment of Deacylated tRNA to the Ribosomal A-Site

SSRN
2020 | Other
DOI: 10.2139/ssrn.3600424
EID:

2-s2.0-85109935791

Part of ISSN: 15565068
Contributors: Takada, H.; Roghanian, M.; Caballero-Montes, J.; van Nerom, K.; Jimmy, S.; Kudrin, P.; Trebini, F.; Murayama, R.; Akanuma, G.; Garcia-Pino, A. et al.
Source: Self-asserted source
Hiraku Takada via Scopus - Elsevier

Structural basis for bacterial ribosome quality control

bioRxiv
2020 | Other
DOI: 10.1101/2020.09.03.281279
EID:

2-s2.0-85098900304

Part of ISSN: 26928205
Contributors: Crowe-McAuliffe, C.; Takada, H.; Murina, V.; Polte, C.; Kasvandik, S.; Tenson, T.; Ignatova, Z.; Atkinson, G.C.; Wilson, D.N.; Hauryliuk, V.
Source: Self-asserted source
Hiraku Takada via Scopus - Elsevier

Structural basis of resistance to lincosamide, streptogramin A, and pleuromutilin antibiotics by ABCF ATPases in gram-positive pathogens

bioRxiv
2020 | Other
DOI: 10.1101/2020.11.24.396648
EID:

2-s2.0-85099134320

Part of ISSN: 26928205
Contributors: Crowe-McAuliffe, C.; Murina, V.; Turnbull, K.J.; Kasari, M.; Mohamad, M.; Polte, C.; Takada, H.; Vaitkevicius, K.; Johansson, J.; Ignatova, Z. et al.
Source: Self-asserted source
Hiraku Takada via Scopus - Elsevier

The C-Terminal RRM/ACT Domain Is Crucial for Fine-Tuning the Activation of ‘Long’ RelA-SpoT Homolog Enzymes by Ribosomal Complexes

Frontiers in Microbiology
2020 | Journal article
DOI: 10.3389/fmicb.2020.00277
EID:

2-s2.0-85082552430

Part of ISSN: 1664302X
Contributors: Takada, H.; Roghanian, M.; Murina, V.; Dzhygyr, I.; Murayama, R.; Akanuma, G.; Atkinson, G.C.; Garcia-Pino, A.; Hauryliuk, V.
Source: Self-asserted source
Hiraku Takada via Scopus - Elsevier

A widespread toxin-antitoxin system exploiting growth control via alarmone signalling

bioRxiv
2019 | Other
DOI: 10.1101/575399
EID:

2-s2.0-85094380859

Part of ISSN: 26928205
Contributors: Jimmy, S.; Saha, C.K.; Stavropoulos, C.; Oliveira, S.R.A.; Kurata, T.; Koh, A.; Cepauskas, A.; Takada, H.; Tenson, T.; Strahl, H. et al.
Source: Self-asserted source
Hiraku Takada via Scopus - Elsevier

ABCF ATPases Involved in Protein Synthesis, Ribosome Assembly and Antibiotic Resistance: Structural and Functional Diversification across the Tree of Life

Journal of Molecular Biology
2019 | Journal article
DOI: 10.1016/j.jmb.2018.12.013
EID:

2-s2.0-85060093624

Part of ISSN: 10898638 00222836
Contributors: Murina, V.; Kasari, M.; Takada, H.; Hinnu, M.; Saha, C.K.; Grimshaw, J.W.; Seki, T.; Reith, M.; Putrinš, M.; Tenson, T. et al.
Source: Self-asserted source
Hiraku Takada via Scopus - Elsevier

Nucleotide-mediated allosteric regulation of bifunctional Rel enzymes

bioRxiv
2019 | Other
DOI: 10.1101/670703
EID:

2-s2.0-85095640985

Part of ISSN: 26928205
Contributors: Tamman, H.; van Nerom, K.; Takada, H.; Vandenberk, N.; Scholl, D.; Polikanov, Y.; Hofkens, J.; Talavera, A.; Hauryliuk, V.; Hendrix, J. et al.
Source: Self-asserted source
Hiraku Takada via Scopus - Elsevier

The C-terminal RRM/ACT domain is crucial for fine-tuning the activation of 'long' RelA-SpoT Homolog enzymes by ribosomal complexes

bioRxiv
2019 | Other
DOI: 10.1101/849810
EID:

2-s2.0-85094383753

Part of ISSN: 26928205
Contributors: Takada, H.; Roghanian, M.; Murina, V.; Dzhygyr, I.; Murayama, R.; Akanuma, G.; Atkinson, G.C.; Garcia-Pino, A.; Hauryliuk, V.
Source: Self-asserted source
Hiraku Takada via Scopus - Elsevier

The Rel stringent factor from Thermus thermophilus: Crystallization and X-ray analysis

Acta Crystallographica Section F: Structural Biology Communications
2019 | Journal article
DOI: 10.1107/S2053230X19010628
EID:

2-s2.0-85070531465

Part of ISSN: 2053230X
Contributors: Van Nerom, K.; Tamman, H.; Takada, H.; Hauryliuk, V.; Garcia-Pino, A.
Source: Self-asserted source
Hiraku Takada via Scopus - Elsevier

Elimination of Ribosome Inactivating Factors Improves the Efficiency of Bacillus subtilis and Saccharomyces cerevisiae Cell-Free Translation Systems

Frontiers in Microbiology
2018 | Journal article
DOI: 10.3389/fmicb.2018.03041
EID:

2-s2.0-85082559395

Part of ISSN: 1664302X
Contributors: Brodiazhenko, T.; Johansson, M.J.O.; Takada, H.; Nissan, T.; Hauryliuk, V.; Murina, V.
Source: Self-asserted source
Hiraku Takada via Scopus - Elsevier

Elimination of ribosome inactivating factors improves the efficiency of Bacillus subtilis and Saccharomyces cerevisiae cell-free translational systems

bioRxiv
2018 | Other
DOI: 10.1101/424044
EID:

2-s2.0-85093412555

Part of ISSN: 26928205
Contributors: Brodiazhenko, T.; Johansson, M.; Takada, H.; Nissan, T.; Hauryliuk, V.; Murina, V.
Source: Self-asserted source
Hiraku Takada via Scopus - Elsevier

Essentiality and function of WalK/WalR two-component system: The past, present, and future of research

Bioscience, Biotechnology and Biochemistry
2018 | Journal article
DOI: 10.1080/09168451.2018.1444466
EID:

2-s2.0-85046631699

Part of ISSN: 13476947 09168451
Contributors: Takada, H.; Yoshikawa, H.
Source: Self-asserted source
Hiraku Takada via Scopus - Elsevier

Essentiality of walRK for growth in bacillus subtilis and its role during heat stress

Microbiology (United Kingdom)
2018 | Journal article
DOI: 10.1099/mic.0.000625
EID:

2-s2.0-85045151828

Part of ISSN: 14652080 13500872
Contributors: Takada, H.; Shiwa, Y.; Takino, Y.; Osaka, N.; Ueda, S.; Watanabe, S.; Chibazakura, T.; Su’Etsugu, M.; Utsumi, R.; Yoshikawa, H.
Source: Self-asserted source
Hiraku Takada via Scopus - Elsevier

Structural basis for antibiotic resistance mediated by the Bacillus subtilis ABCF ATPase VmlR

Proceedings of the National Academy of Sciences of the United States of America
2018 | Journal article
DOI: 10.1073/pnas.1808535115
EID:

2-s2.0-85052758620

Part of ISSN: 10916490 00278424
Contributors: Crowe-McAuliffe, C.; Graf, M.; Huter, P.; Takada, H.; Abdelshahid, M.; Nováček, J.; Murina, V.; Atkinson, G.C.; Hauryliuk, V.; Wilson, D.N.
Source: Self-asserted source
Hiraku Takada via Scopus - Elsevier

ABCF ATPases involved in protein synthesis, ribosome assembly and antibiotic resistance: Structural and functional diversification across the tree of life

bioRxiv
2017 | Other
DOI: 10.1101/220046
EID:

2-s2.0-85093382870

Part of ISSN: 26928205
Contributors: Murina, V.; Kasari, M.; Takada, H.; Hinnu, M.; Saha, C.K.; Grimshaw, J.W.; Seki, T.; Reith, M.; Putrinš, M.; Tenson, T. et al.
Source: Self-asserted source
Hiraku Takada via Scopus - Elsevier

Exponential propagation of large circular DNA by reconstitution of a chromosome-replication cycle

Nucleic Acids Research
2017 | Journal article
DOI: 10.1093/nar/gkx822
EID:

2-s2.0-85038024935

Part of ISSN: 13624962 03051048
Contributors: Su’etsugu, M.; Takada, H.; Katayama, T.; Tsujimoto, H.
Source: Self-asserted source
Hiraku Takada via Scopus - Elsevier

Overall Shapes of the SMC-ScpAB Complex Are Determined by Balance between Constraint and Relaxation of Its Structural Parts

Structure
2017 | Journal article
DOI: 10.1016/j.str.2017.02.008
EID:

2-s2.0-85014599850

Part of ISSN: 18784186 09692126
Contributors: Kamada, K.; Su'etsugu, M.; Takada, H.; Miyata, M.; Hirano, T.
Source: Self-asserted source
Hiraku Takada via Scopus - Elsevier

Differential regulation of rRNA and tRNA transcription from the rRNA-tRNA composite operon in Escherichia coli

PLoS ONE
2016 | Journal article
DOI: 10.1371/journal.pone.0163057
EID:

2-s2.0-85007310337

Part of ISSN: 19326203
Contributors: Takada, H.; Shimada, T.; Dey, D.; Quyyum, M.Z.; Nakano, M.; Ishiguro, A.; Yoshida, H.; Yamamoto, K.; Sen, R.; Ishihama, A.
Source: Self-asserted source
Hiraku Takada via Scopus - Elsevier

Expanded roles of two-component response regulator OmpR in Escherichia coli: Genomic SELEX search for novel regulation targets

Genes to Cells
2015 | Journal article
DOI: 10.1111/gtc.12282
EID:

2-s2.0-84946497929

Part of ISSN: 13652443 13569597
Contributors: Shimada, T.; Takada, H.; Yamamoto, K.; Ishihama, A.
Source: Self-asserted source
Hiraku Takada via Scopus - Elsevier

An essential enzyme for phospholipid synthesis associates with the Bacillus subtilis divisome

Molecular Microbiology
2014 | Journal article
DOI: 10.1111/mmi.12457
EID:

2-s2.0-84891925148

Part of ISSN: 0950382X 13652958
Contributors: Takada, H.; Fukushima-Tanaka, S.; Morita, M.; Kasahara, Y.; Watanabe, S.; Chibazakura, T.; Hara, H.; Matsumoto, K.; Yoshikawa, H.
Source: Self-asserted source
Hiraku Takada via Scopus - Elsevier

Cell motility and biofilm formation in Bacillus subtilis are affected by the ribosomal proteins, S11 and S21

Bioscience, Biotechnology and Biochemistry
2014 | Journal article
DOI: 10.1080/09168451.2014.915729
EID:

2-s2.0-84925884640

Part of ISSN: 13476947 09168451
Contributors: Takada, H.; Morita, M.; Shiwa, Y.; Sugimoto, R.; Suzuki, S.; Kawamura, F.; Yoshikawa, H.
Source: Self-asserted source
Hiraku Takada via Scopus - Elsevier

Regulation of nuclear envelope dynamics via APC/C is necessary for the progression of semi-open mitosis in Schizosaccharomyces japonicus

Genes to Cells
2013 | Journal article
DOI: 10.1111/gtc.12072
EID:

2-s2.0-84883193638

Part of ISSN: 13569597 13652443
Contributors: Aoki, K.; Shiwa, Y.; Takada, H.; Yoshikawa, H.; Niki, H.
Source: Self-asserted source
Hiraku Takada via Scopus - Elsevier
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