Personal information

Emails & domains

Verified email domains

Websites & social links

CCR, NCI, NIH Website

Other IDs

ResearcherID: B-3110-2015

Keywords

complex genetic traits, mTOR, p16, HDAC inhibitor, MYC

Countries

United States

Activities

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Employment (1)

National Cancer Institute: Bethesda, MD, US

1984-12 to present | Deputy Chief (Laboratory of Cancer Biology and Genetics)
Employment
Source: Self-asserted source
Beverly Mock

Education and qualifications (1)

Univeristy of Maryland: College Park, MD, US

1981-09 to 1984-12 | Ph.D. (Zoology)
Education
Source: Self-asserted source
Beverly Mock

Works (27)

Transfer RNA acetylation regulates in vivo mammalian stress signaling

Science Advances
2025-03-19 | Journal article | Author
DOI: 10.1126/sciadv.ads2923
Contributors: Shuo Gu; Kent Hunter; Schraga Schwartz; Joseph Georgeson; Jordan Meier; Beverly Mock; Mitchell R. O'Connell; Colin Chih-Chien Wu; Parthav Jailwala; Joe Nguyen et al.
Source: check_circle
AAAS - Science

Use of CRISPR-based screens to identify mechanisms of chemotherapy resistance

Cancer Gene Therapy
2023-08 | Journal article
DOI: 10.1038/s41417-023-00608-z
Contributors: George Alyateem; Heidi M. Wade; Aaron A. Bickert; Crystal C. Lipsey; Priya Mondal; MacKinzie D. Smith; Rania M. Labib; Beverly A. Mock; Robert W. Robey; Michael M. Gottesman
Source: check_circle
Crossref

Conditional deletion of mTOR discloses its essential role in early B‐cell development

Molecular Carcinogenesis
2022-04 | Journal article
DOI: 10.1002/mc.23386
Contributors: Shuling Zhang; Wendy Dubois; Xingmin Feng; Joe T. Nguyen; Neal S. Young; Beverly A. Mock
Source: check_circle
Crossref

The transcription factor MZF1 differentially regulates murine Mtor promoter variants linked to tumor susceptibility

Journal of Biological Chemistry
2019-11-08 | Journal article
DOI: 10.1074/jbc.RA119.009779
Contributors: Shuling Zhang; Wei Shi; Edward S. Ramsay; Valery Bliskovsky; Adrian Max Eiden; Daniel Connors; Matthew Steinsaltz; Wendy DuBois; Beverly A. Mock
Source: check_circle
Crossref

The Reign of Antibodies: A Celebration of and Tribute to Michael Potter and His Homogeneous Immunoglobulin Workshops

The Journal of Immunology
2018-01-01 | Journal article
DOI: 10.4049/jimmunol.1701516
Contributors: Patricia J Gearhart; Beverly A Mock; Rafael Casellas; Michael P Cancro
Source: check_circle
Crossref

mTOR intersects antibody-inducing signals from TACI in marginal zone B cells

Nature Communications
2017-12 | Journal article
DOI: 10.1038/s41467-017-01602-4
Contributors: Jordi Sintes; Maurizio Gentile; Shuling Zhang; Yolanda Garcia-Carmona; Giuliana Magri; Linda Cassis; Daniel Segura-Garzón; Alessandra Ciociola; Emilie K. Grasset; Sabrina Bascones et al.
Source: check_circle
Crossref

Loss-of-function RNAi screens in breast cancer cells identify AURKB, PLK1, PIK3R1, MAPK12, PRKD2, and PTK6 as sensitizing targets of rapamycin activity

Cancer Letters
2014 | Journal article
DOI:

10.1016/j.canlet.2014.08.043
Contributors: Ou, Oliver; Huppi, Konrad; Chakka, Sirisha; Gehlhaus, Kristen; Dubois, Wendy; Patel, Jyoti; Chen, Jinqiu; Mackiewicz, Mark; Jones, Tamara L.; Pitt, Jason J. et al.
Source: Self-asserted source
Beverly Mock via ResearcherID

TORC1 and class I HDAC inhibitors synergize to suppress mature B cell neoplasms

Molecular Oncology
2014 | Journal article
DOI:

10.1016/j.molonc.2013.11.007
Contributors: Simmons, John K.; Patel, Jyoti; Michalowski, Aleksandra; Zhang, Shuling; Wei, Bih-Rong; Sullivan, Patrick; Gamache, Ben; Felsenstein, Kenneth; Kuehl, W. Michael; Simpson, R. Mark et al.
Source: Self-asserted source
Beverly Mock via ResearcherID

A functional genomics approach for identification of sirolimus sensitizer genes regulated by HDAC inhibitors.

Cancer Research
2013 | Journal article
DOI:

10.1158/1538-7445.AM2013-4408
Contributors: Gamache, Benjamin J.; Simmons, John; Patel, Jyoti; Ou, Lihui; Michalowski, Aleksandra; Sullivan, Patrick; Wei, Bih-Rong; Simpson, R. Mark; Zhang, Shuling; Zhang, Ke et al.
Source: Self-asserted source
Beverly Mock via ResearcherID

A novel KIT-deficient mouse mast cell model for the examination of human KIT-mediated activation responses

Journal of Immunological Methods
2013 | Journal article
DOI:

10.1016/j.jim.2013.01.008
Contributors: Smrz, Daniel; Bandara, Geethani; Zhang, Shuling; Mock, Beverly A.; Beaven, Michael A.; Metcalfe, Dean D.; Gilfillan, Alasdair M.
Source: Self-asserted source
Beverly Mock via ResearcherID

A systems pharmacogenomic approach to identify synergistic molecular mechanisms of combined mTOR/HDAC inhibition.

Cancer Research
2013 | Journal article
DOI:

10.1158/1538-7445.AM2013-2217
Contributors: Simmons, John K.; Michalowski, Aleksandra M.; Gamache, Ben; Patel, Jyoti; Zingone, Adriana; Zhang, Ke; Kuehl, Michael; Huang, Jing; Landgren, Ola; Mock, Beverly A.
Source: Self-asserted source
Beverly Mock via ResearcherID

B Cell-Specific Deficiencies in mTOR Limit Humoral Immune Responses

Journal of Immunology
2013 | Journal article
DOI:

10.4049/jimmunol.1201767
Contributors: Zhang, Shuling; Pruitt, Margaret; Dena Tran; Du Bois, Wendy; Zhang, Ke; Patel, Rushi; Hoover, Shelley; Simpson, R. Mark; Simmons, John; Gary, Joy et al.
Source: Self-asserted source
Beverly Mock via ResearcherID

Increased Mammalian Lifespan and a Segmental and Tissue-Specific Slowing of Aging after Genetic Reduction of mTOR Expression

Cell Reports
2013 | Journal article
DOI:

10.1016/j.celrep.2013.07.030
Contributors: Wu, J. Julie; Liu, Jie; Chen, Edmund B.; Wang, Jennifer J.; Cao, Liu; Narayan, Nisha; Fergusson, Marie M.; Rovira, Ilsa I.; Allen, Michele; Springer, Danielle A. et al.
Source: Self-asserted source
Beverly Mock via ResearcherID

Use of a mouse model of constitutive mTOR inhibition to identify molecular modulators of acquired resistance

Cancer Research
2013 | Journal article
DOI:

10.1158/1538-7445.AM2013-1555
Contributors: Gary, Joy; Xu, Jinfei; Simmons, John; Kovalchuk, Alexander; Dubois, Wendy; Testa, Joseph; Mock, Beverly
Source: Self-asserted source
Beverly Mock via ResearcherID

Mouse genetics 2011: meeting report.

Mammalian genome : official journal of the International Mammalian Genome Society
2012 | Journal article
DOI:

10.1007/s00335-012-9390-6
Contributors: Simmons, John K; Amlin-Van Schaick, Jessica C; Geiger, Thomas R; Reilly, Karlyne; Hunter, Kent; Mock, Beverly A
Source: Self-asserted source
Beverly Mock via ResearcherID

CASZ1, a candidate tumor-suppressor gene, suppresses neuroblastoma tumor growth through reprogramming gene expression

Cell Death and Differentiation
2011 | Journal article
DOI:

10.1038/cdd.2010.187
Contributors: Liu, Z.; Yang, X.; Li, Z.; McMahon, C.; Sizer, C.; Barenboim-Stapleton, L.; Bliskovsky, V.; Mock, B.; Ried, T.; London, W. B. et al.
Source: Self-asserted source
Beverly Mock via ResearcherID

mTORC1 and mTORC2 differentially regulate homeostasis of neoplastic and non-neoplastic human mast cells

Blood
2011 | Journal article
DOI:

10.1182/blood-2011-06-359984
Contributors: Smrz, Daniel; Kim, Mi-Sun; Zhang, Shuling; Mock, Beverly A.; Smrzova, Sarka; DuBois, Wendy; Simakova, Olga; Maric, Irina; Wilson, Todd M.; Metcalfe, Dean D. et al.
Source: Self-asserted source
Beverly Mock via ResearcherID

GSE17297: Mndal, a new interferon-inducible family member, suppresses cell growth and may modify plasmacytoma susceptibility.

Gene Expression Omnibus
2009 | Other
Contributors: Zhang, Ke; Kagan, Daniel; DuBois, Wendy; Robinson, Richard; Bliskovsky, Valery; Vass, William C; Zhang, Shuling; Mock, Beverly A
Source: Self-asserted source
Beverly Mock via ResearcherID

GSM432896: BALB/c control (bmsnmix8).

Gene Expression Omnibus
2009 | Other
Contributors: Zhang, Ke; Kagan, Daniel; DuBois, Wendy; Robinson, Richard; Bliskovsky, Valery; Vass, William C; Zhang, Shuling; Mock, Beverly A
Source: Self-asserted source
Beverly Mock via ResearcherID

GSM432899: DBA d18 (120msn).

Gene Expression Omnibus
2009 | Other
Contributors: Zhang, Ke; Kagan, Daniel; DuBois, Wendy; Robinson, Richard; Bliskovsky, Valery; Vass, William C; Zhang, Shuling; Mock, Beverly A
Source: Self-asserted source
Beverly Mock via ResearcherID

GSM432900: DBA d18 (123msn).

Gene Expression Omnibus
2009 | Other
Contributors: Zhang, Ke; Kagan, Daniel; DuBois, Wendy; Robinson, Richard; Bliskovsky, Valery; Vass, William C; Zhang, Shuling; Mock, Beverly A
Source: Self-asserted source
Beverly Mock via ResearcherID

GSM432902: DBA control (122msn).

Gene Expression Omnibus
2009 | Other
Contributors: Zhang, Ke; Kagan, Daniel; DuBois, Wendy; Robinson, Richard; Bliskovsky, Valery; Vass, William C; Zhang, Shuling; Mock, Beverly A
Source: Self-asserted source
Beverly Mock via ResearcherID

GSM432903: DBA control (124-5msn).

Gene Expression Omnibus
2009 | Other
Contributors: Zhang, Ke; Kagan, Daniel; DuBois, Wendy; Robinson, Richard; Bliskovsky, Valery; Vass, William C; Zhang, Shuling; Mock, Beverly A
Source: Self-asserted source
Beverly Mock via ResearcherID

GSM432908: BALB/c control (199msn).

Gene Expression Omnibus
2009 | Other
Contributors: Zhang, Ke; Kagan, Daniel; DuBois, Wendy; Robinson, Richard; Bliskovsky, Valery; Vass, William C; Zhang, Shuling; Mock, Beverly A
Source: Self-asserted source
Beverly Mock via ResearcherID

GSM432920: DBA control (202msn).

Gene Expression Omnibus
2009 | Other
Contributors: Zhang, Ke; Kagan, Daniel; DuBois, Wendy; Robinson, Richard; Bliskovsky, Valery; Vass, William C; Zhang, Shuling; Mock, Beverly A
Source: Self-asserted source
Beverly Mock via ResearcherID

GSM432921: DBA control (203msn).

Gene Expression Omnibus
2009 | Other
Contributors: Zhang, Ke; Kagan, Daniel; DuBois, Wendy; Robinson, Richard; Bliskovsky, Valery; Vass, William C; Zhang, Shuling; Mock, Beverly A
Source: Self-asserted source
Beverly Mock via ResearcherID

Mndal, a new interferon-inducible family member, is highly polymorphic, suppresses cell growth, and may modify plasmacytoma susceptibility

Blood
2009 | Journal article
DOI:

10.1182/blood-2009-01-198812
Contributors: Zhang, Ke; Kagan, Daniel; DuBois, Wendy; Robinson, Richard; Bliskovsky, Valery; Vass, William C.; Zhang, Shuling; Mock, Beverly A.
Source: Self-asserted source
Beverly Mock via ResearcherID
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