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ResearcherID: J-6362-2014
Scopus Author ID: 56319550800

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Czech Republic

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Employment (3)

Mendel University in Brno: Brno, CZ

Researcher (Faculty of AgriSciences/Department of Chemistry and Biochemistry)
Employment
Source: check_circle
Mendel University in Brno

Mendel University Brno: Brno, CZ

2020-01-01 to present | Principal Investigator (Department of Chemistry and Biochemistry)
Employment
Source: Self-asserted source
Ladislav Sivák

Institute of Microbiology of the CAS, v. v. i.: Prague, CZ

2011-11-01 to 2019-12-31
Employment
Source: Self-asserted source
Ladislav Sivák

Professional activities (1)

Czech Immunological Society: Prague, CZ

2011-11-26 to present
Membership
Source: Self-asserted source
Ladislav Sivák

Works (21)

Engineered human H-chain ferritin with reversed charge of the internal cavity exhibits RNA-mediated spongelike effect for loading RNA/DNA-binding molecules

Biomaterials Science
2024 | Journal article
DOI: 10.1039/D3BM01257C
Contributors: Marketa Charousova; Marie Kudlickova Peskova; Paulina Takacsova; Katerina Kapolkova; Yazan Haddad; Jan Bilek; Ladislav Sivak; Tomas Bartejs; Zbynek Heger; Vladimir Pekarik
Source: check_circle
Crossref

In vivo evaluation of selenium-tellurium based nanoparticles as a novel treatment for bovine mastitis

Journal of Animal Science and Biotechnology
2024 | Journal article
DOI: 10.1186/S40104-024-01128-Y
WOSUID: WOS:001381659800001
Contributors: Kosaristanova, Ludmila; Bytesnikova, Zuzana; Fialova, Tatiana; Pekarkova, Jana; Svec, Pavel; Ondreas, Frantisek; Jemelikova, Vendula; Ridoskova, Andrea; Makovicky, Peter; Sivak, Ladislav et al.
Source: check_circle
Web of Science Researcher Profile Sync
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Neutrophils in Cancer immunotherapy: friends or foes?

Molecular Cancer
2024-05-18 | Journal article
DOI: 10.1186/s12943-024-02004-z
Part of ISSN: 1476-4598
Contributors: Xueqin Huang; Eugenie Nepovimova; Vojtech Adam; Ladislav Sivak; Zbynek Heger; Marian Valko; Qinghua Wu; Kamil Kuca
Source: Self-asserted source
Ladislav Sivák

Metallothionein-3 is a multifunctional driver that modulates the development of sorafenib-resistant phenotype in hepatocellular carcinoma cells

Biomarker Research
2024-04-09 | Journal article
DOI: 10.1186/s40364-024-00584-y
Part of ISSN: 2050-7771
Contributors: Miguel Angel Merlos Rodrigo; Hana Michalkova; Ana Maria Jimenez Jimenez; Frantisek Petrlak; Tomas Do; Ladislav Sivak; Yazan Haddad; Petra Kubickova; Vivian de los Rios; J. Ignacio Casal et al.
Source: Self-asserted source
Ladislav Sivák
grade
Preferred source (of 2)‎

Proteinase-activated Receptor 2: Springboard of Tumors

Anticancer Research
2024-01 | Journal article
DOI: 10.21873/anticanres.16782
Part of ISSN: 0250-7005
Part of ISSN: 1791-7530
Contributors: DAVID VETVICKA; PETR SUHAJ; TOMAS OLEJAR; LADISLAV SIVAK; JIRI BENES; PAVLA POUCKOVA
Source: Self-asserted source
Ladislav Sivák

Inhibitors of phosphoinositide 3-kinase (PI3K) and phosphoinositide 3-kinase-related protein kinase family (PIKK)

Journal of Enzyme Inhibition and Medicinal Chemistry
2023-12-31 | Journal article
DOI: 10.1080/14756366.2023.2237209
Part of ISSN: 1475-6366
Part of ISSN: 1475-6374
Contributors: Xueqin Huang; Li You; Eugenie Nepovimova; Miroslav Psotka; David Malinak; Marian Valko; Ladislav Sivak; Jan Korabecny; Zbynek Heger; Vojtech Adam et al.
Source: Self-asserted source
Ladislav Sivák

BODIPY-labelled acetylcholinesterase reactivators can be encapsulated into ferritin nanovehicles for enhanced bioavailability in the CNS

Biomedicine & Pharmacotherapy
2023-11 | Journal article | Author
DOI: 10.1016/j.biopha.2023.115490
Part of ISSN: 0753-3322
Contributors: Eliska Prchalova; Martina Sukupova; David Malinak; Rudolf Andrýs; Ladislav Sivák ; Vladimir Pekarik; Adam Skarka; Jana Svobodova; Lukas Prchal; Lukas Fresser et al.
Source: Self-asserted source
Ladislav Sivák
grade
Preferred source (of 2)‎

Platinum-based drug-induced depletion of amino acids in the kidneys and liver

Frontiers in Oncology
2022 | Journal article
DOI: 10.3389/fonc.2022.986045
Part of ISSN: 2234-943X
EID:

2-s2.0-85139452521

OTHER-ID:

OBD43923687
Source: check_circle
Mendel University in Brno

Toward understanding the kinetics of disassembly of ferritins of varying origin and subunit composition

Applied Materials Today
2022-08 | Journal article
DOI: 10.1016/j.apmt.2022.101535
Part of ISSN: 2352-9407
Source: Self-asserted source
Ladislav Sivák

HPMA Copolymer Mebendazole Conjugate Allows Systemic Administration and Possesses Antitumour Activity In Vivo

Pharmaceutics
2022-06-04 | Journal article
DOI: 10.3390/pharmaceutics14061201
Contributors: Martin Studenovský; Anna Rumlerová; Jiřina Kovářová; Barbora Dvořáková; Ladislav Sivák; Libor Kostka; Daniel Berdár; Tomáš Etrych; Marek Kovář
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Crossref
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Simultaneous Delivery of Doxorubicin and Protease Inhibitor Derivative to Solid Tumors via Star-Shaped Polymer Nanomedicines Overcomes P-gp- and STAT3-Mediated Chemoresistance

Biomacromolecules
2022-05-18 | Journal article
DOI: 10.1021/acs.biomac.2c00256
Part of ISSN: 1525-7797
Part of ISSN: 1526-4602
Source: Self-asserted source
Ladislav Sivák

IL-2/JES6-1 mAb complexes dramatically increase sensitivity to LPS through IFN-γ production by CD25\textsuperscript+Foxp3\textsuperscript- T cells

eLife
2021-12 | Journal article
DOI: 10.7554/eLife.62432
Part of ISSN: 2050-084X
Source: Self-asserted source
Ladislav Sivák

Polymer-ritonavir derivate nanomedicine with pH-sensitive activation possesses potent anti-tumor activity in vivo via inhibition of proteasome and STAT3 signaling.

Journal of controlled release : official journal of the Controlled Release Society
2021-03-12 | Journal article
DOI: 10.1016/j.jconrel.2021.03.015
PMID: 33722611
Source: Self-asserted source
Ladislav Sivák

Gene silencing delivery systems for the treatment of pancreatic cancer: Where and what to target next?

Journal of controlled release : official journal of the Controlled Release Society
2021-01-19 | Journal article
DOI: 10.1016/j.jconrel.2021.01.020
PMID: 33482273
Source: Self-asserted source
Ladislav Sivák

Overcoming multidrug resistance via simultaneous delivery of cytostatic drug and P-glycoprotein inhibitor to cancer cells by HPMA copolymer conjugate

Biomaterials
2017 | Journal article
DOI: 10.1016/j.biomaterials.2016.11.013
EID:

2-s2.0-84996721474
Contributors: Sivak, L.; Subr, V.; Tomala, J.; Rihova, B.; Strohalm, J.; Etrych, T.; Kovar, M.
Source: Self-asserted source
Ladislav Sivák via Scopus - Elsevier

Polymer nitric oxide donors potentiate the treatment of experimental solid tumours by increasing drug accumulation in the tumour tissue.

Journal of controlled release : official journal of the Controlled Release Society
2017-11-16 | Journal article
DOI: 10.1016/j.jconrel.2017.11.017
PMID: 29154977
Source: Self-asserted source
Ladislav Sivák

Tumor-targeted micelle-forming block copolymers for overcoming of multidrug resistance

Journal of Controlled Release
2017-01 | Journal article
DOI: 10.1016/j.jconrel.2016.11.020
Contributors: Alena Braunová; Libor Kostka; Ladislav Sivák; Lucie Cuchalová; Zuzana Hvězdová; Richard Laga; Sergey Filippov; Peter Černoch; Michal Pechar; Olga Janoušková et al.
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Crossref
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Overcoming multidrug resistance in Dox-resistant neuroblastoma cell lines via treatment with HPMA copolymer conjugates containing anthracyclines and P-gp inhibitors.

2016-05 | Journal article
DOI: 10.1016/j.jconrel.2016.05.036
PMID: 27189135
Contributors: Koziolová E; Janoušková O; Cuchalová L; Hvězdová Z; Hraběta J; Eckschlager T; Sivák L; Ulbrich K; Etrych T; Šubr V
Source: Self-asserted source
Ladislav Sivák via Europe PubMed Central
grade
Preferred source (of 2)‎

Polymer inhibitors of ABC transporter overcoming multidrug resistance: Synthesis, characterization and in vitro evaluation.

2015-09 | Journal article
DOI: 10.1016/j.jconrel.2015.05.180
PMID: 27005035
Contributors: Šubr V; Koziolová E; Sivák L; Říhová B; Kovář M; Ulbrich K
Source: Self-asserted source
Ladislav Sivák via Europe PubMed Central

Synthesis of Poly[N-(2-hydroxypropyl)methacrylamide] Conjugates of Inhibitors of the ABC Transporter That Overcome Multidrug Resistance in Doxorubicin-Resistant P388 Cells in Vitro.

Biomacromolecules
2014 | Journal article
DOI: 10.1021/bm500649q
Part of ISSN: 1526-4602
Contributors: Subr, V; Sivak, L; Koziolova, E; Braunova, A; Pechar, M; Strohalm, J; Kabesova, M; Rihova, B; Ulbrich, K; Kovar, M
Source: Self-asserted source
Ladislav Sivák via ResearcherID
grade
Preferred source (of 2)‎

Overcoming multidrug resistance with inhibitor of ABC transporters bound to HPMA copolymer carrier as a novel therapeutic approach in cancer treatment

Immunology
2012 | Journal article
Part of ISSN: 0019-2805
Contributors: Kabesova, M.; Sivak, L.; Subr, V.; Ulbrich, K.; Kovar, M.; Rihova, B.
Source: Self-asserted source
Ladislav Sivák via ResearcherID
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