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Scopus Author ID: 8226338900
ResearcherID: S-5572-2017

Countries

Czech Republic

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Employment (2)

Charles University, Faculty of Pharmacy in Hradec Kralove: Hradec Kralove, CZ

2014-06-01 to present | associate professor (Department of Biochemical Sciences)
Employment
Source: Self-asserted source
Bousova

Charles University, Faculty of Pharmacy in Hradec Kralove: Hradec Kralove, CZ

2006-04-10 to 2014-05-31 | teacher/researcher (Department of Biochemical Sciences)
Employment
Source: Self-asserted source
Bousova

Education and qualifications (2)

Charles University, Faculty of Pharmacy in Hradec Kralove: Hradec Kralove, CZ

2002-09 to 2006-10 | Ph.D. (Department of Biochemical Sciences)
Education
Source: Self-asserted source
Bousova

Charles University, Faculty of Pharmacy in Hradec Kralove: Hradec Kralove, CZ

1997-10-01 to 2002-06-10 | Mgr.
Education
Source: Self-asserted source
Bousova

Funding (1)

Metabolism of terpenes and mechanisms of their toxic effects in human liver

2018-01 to 2020-12 | Grant
Grantová Agentura České Republiky (Prague, Czech Republic, CZ)
GRANT_NUMBER:

18-09946S
Source: Self-asserted source
Bousova

Works (46)

Metabolic dysfunction-associated steatotic liver disease-induced changes in the antioxidant system: a review

Archives of Toxicology
2025-01 | Journal article
DOI: 10.1007/s00204-024-03889-x
Contributors: Gabriela Svobodová; Martin Horní; Eva Velecká; Iva Boušová
Source: check_circle
Crossref

In vitro metabolism of helenalin and its inhibitory effect on human cytochrome P450 activity

Archives of Toxicology
2022-03 | Journal article
DOI: 10.1007/s00204-021-03218-6
Contributors: Michaela Šadibolová; Risto O. Juvonen; Seppo Auriola; Iva Boušová
Source: check_circle
Crossref

MicroRNAs mediated regulation of glutathione peroxidase 7 expression and its changes during adipogenesis

Biochimica et Biophysica Acta - Gene Regulatory Mechanisms
2021 | Journal article
DOI: 10.1016/j.bbagrm.2021.194734
EID:

2-s2.0-85111570817

Part of ISSN: 18764320 18749399
Contributors: Hanousková, B.; Vávrová, G.; Ambrož, M.; Boušová, I.; Karlsen, T.A.; Skálová, L.; Matoušková, P.
Source: Self-asserted source
Bousova via Scopus - Elsevier

The Modulation of Phase II Drug-Metabolizing Enzymes in Proliferating and Differentiated CaCo-2 Cells by Hop-Derived Prenylflavonoids

Nutrients
2020-07-18 | Journal article
DOI: 10.3390/nu12072138
Contributors: Kateřina Lněničková; Michaela Šadibolová; Petra Matoušková; Barbora Szotáková; Lenka Skálová; Iva Boušová
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The Hepatotoxicity of Alantolactone and Germacrone: Their Influence on Cholesterol and Lipid Metabolism in Differentiated HepaRG Cells

Nutrients
2020-06-08 | Journal article
DOI: 10.3390/nu12061720
Contributors: Tomáš Zárybnický; Petra Matoušková; Lenka Skálová; Iva Boušová
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The Selection and Validation of Reference Genes for mRNA and microRNA Expression Studies in Human Liver Slices Using RT-qPCR

Genes
2019-09-28 | Journal article
DOI: 10.3390/genes10100763
Contributors: Tomáš Zárybnický; Petra Matoušková; Martin Ambrož; Zdeněk Šubrt; Lenka Skálová; Iva Boušová
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Sesquiterpenes Are Agonists of the Pregnane X Receptor but Do Not Induce the Expression of Phase I Drug-Metabolizing Enzymes in the Human Liver

International Journal of Molecular Sciences
2019-09-14 | Journal article
DOI: 10.3390/ijms20184562
Contributors: Michaela Šadibolová; Tomáš Zárybnický; Tomáš Smutný; Petr Pávek; Zdeněk Šubrt; Petra Matoušková; Lenka Skálová; Iva Boušová
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Antiproliferative Effects of Hop-derived Prenylflavonoids and Their Influence on the Efficacy of Oxaliplatine, 5-fluorouracil and Irinotecan in Human ColorectalC Cells

Nutrients
2019-04-19 | Journal article
DOI: 10.3390/nu11040879
Contributors: Martin Ambrož; Kateřina Lněničková; Petra Matoušková; Lenka Skálová; Iva Boušová
Source: check_circle
Crossref
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Hepatotoxicity of monoterpenes and sesquiterpenes.

Archives of toxicology
2018-09 | Journal article
DOI: 10.1007/s00204-017-2062-2
PMID: 28905185
Source: Self-asserted source
Bousova
grade
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Inter-Individual Variability in Acute Toxicity of R-Pulegone and R-Menthofuran in Human Liver Slices and Their Influence on miRNA Expression Changes in Comparison to Acetaminophen

International Journal of Molecular Sciences
2018-06-19 | Journal article
DOI: 10.3390/ijms19061805
Contributors: Tomáš Zárybnický; Petra Matoušková; Bibiána Lancošová; Zdeněk Šubrt; Lenka Skálová; Iva Boušová
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Effect of Green Tea Extract-Enriched Diets on Insulin and Leptin Levels, Oxidative Stress Parameters and Antioxidant Enzymes Activities in Obese Mice

Polish Journal of Food and Nutrition Sciences
2017 | Journal article
DOI: 10.1515/pjfns-2017-0004
WOSUID:

WOS:000399807300008
Contributors: Bartikova, Hana; Bousova, Iva; Matouskova, Petra; Szotakova, Barbora; Skalova, Lenka
Source: Self-asserted source
Bousova via ResearcherID
grade
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Monosodium glutamate-induced obesity changed the expression and activity of glutathione S-transferases in mouse heart and kidney

Pharmazie
2017 | Journal article
DOI: 10.1691/ph.2017.6886
WOSUID:

WOS:000400953900003
Contributors: Bousova, I.; Kostakova, S.; Matouskova, R.; Bartikova, H.; Szotakova, B.; Skalova, L.
Source: Self-asserted source
Bousova via ResearcherID
grade
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Sulforaphane Alters β-Naphthoflavone-Induced Changes in Activity and Expression of Drug-Metabolizing Enzymes in Rat Hepatocytes

Molecules
2017-11-16 | Journal article
DOI: 10.3390/molecules22111983
Contributors: Kateřina Lněničková; Andrea Dymáková; Barbora Szotáková; Iva Boušová
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Essential Oil from Myrica rubra Leaves Potentiated Antiproliferative and Prooxidative Effect of Doxorubicin and its Accumulation in Intestinal Cancer Cells

Planta Medica
2016 | Journal article
DOI: 10.1055/s-0035-1558083
WOSUID:

WOS:000368084700011
Contributors: Ambroz, Martin; Hanusova, Veronika; Skarka, Adam; Bousova, Iva; Kralova, Vera; Langhasova, Lenka; Skalova, Lenka
Source: Self-asserted source
Bousova via ResearcherID
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Influence of diet supplementation with green tea extract on drug-metabolizing enzymes in a mouse model of monosodium glutamate-induced obesity

European Journal of Nutrition
2016 | Journal article
DOI: 10.1007/s00394-015-0856-7
WOSUID:

WOS:000369309700035
Contributors: Bousova, Iva; Matouskova, Petra; Bartikova, Hana; Szotakova, Barbora; Hanusova, Veronika; Tomankova, Veronika; Anzenbacherova, Eva; Liskova, Barbora; Anzenbacher, Pavel; Skalova, Lenka
Source: Self-asserted source
Bousova via ResearcherID
grade
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Altered cytochrome P450 activities and expression levels in the liver and intestines of the monosodium glutamate-induced mouse model of human obesity

Life Sciences
2015 | Journal article
DOI: 10.1016/j.lfs.2015.04.014
WOSUID:

WOS:000357063900003
Contributors: Tomankova, Veronika; Liskova, Barbora; Skalova, Lenka; Bartikova, Hana; Bousova, Iva; Jourova, Lenka; Anzenbacher, Pavel; Ulrichova, Jitka; Anzenbacherova, Eva
Source: Self-asserted source
Bousova via ResearcherID
grade
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Cranberry extract-enriched diets increase NAD(P)H:quinone oxidoreductase and catalase activities in obese but not in nonobese mice

Nutrition Research
2015 | Journal article
DOI: 10.1016/j.nutres.2015.08.002
WOSUID:

WOS:000362311300007
Contributors: Bousova, Iva; Bartikova, Hana; Matouskova, Petra; Lnenickova, Katerina; Zappe, Lukas; Valentova, Katerina; Szotakova, Barbora; Martin, Jan; Skalova, Lenka
Source: Self-asserted source
Bousova via ResearcherID
grade
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Drug-Metabolizing and Antioxidant Enzymes in Monosodium L-Glutamate Obese Mice

Drug Metabolism and Disposition
2015 | Journal article
DOI: 10.1124/dmd.114.061176
WOSUID:

WOS:000347816800010
Contributors: Matouskova, Petra; Bartikova, Hana; Bousova, Iva; Levorova, Lucie; Szotakova, Barbora; Skalova, Lenka
Source: Self-asserted source
Bousova via ResearcherID
grade
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Effect of oral administration of green tea extract in various dosage schemes on oxidative stress status of mice in vivo

Acta Pharmaceutica
2015 | Journal article
DOI: 10.1515/acph-2015-0007
WOSUID:

WOS:000350879000006
Contributors: Bartikova, Hana; Skalova, Lenka; Valentova, Katerina; Matouskova, Petra; Szotakova, Barbora; Martin, Jan; Kvita, Vojtech; Bousova, Iva
Source: Self-asserted source
Bousova via ResearcherID
grade
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Oxidation as an important factor of protein damage: Implications for Maillard reaction

Journal of Biosciences
2015 | Journal article
DOI: 10.1007/s12038-015-9523-7
WOSUID:

WOS:000355068100021
Contributors: Trnkova, L.; Drsata, J.; Bousova, I.
Source: Self-asserted source
Bousova via ResearcherID
grade
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The Influence of Sesquiterpenes from Myrica rubra on the Antiproliferative and Pro-Oxidative Effects of Doxorubicin and Its Accumulation in Cancer Cells

Molecules
2015 | Journal article
DOI: 10.3390/molecules200815343
WOSUID:

WOS:000361375400112
Contributors: Ambroz, Martin; Bousova, Iva; Skarka, Adam; Hanusova, Veronika; Kralova, Vera; Matouskova, Petra; Szotakova, Barbora; Skalova, Lenka
Source: Self-asserted source
Bousova via ResearcherID
grade
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The modulation of carbonyl reductase 1 by polyphenols

Drug Metabolism Reviews
2015 | Journal article
DOI: 10.3109/03602532.2015.1089885
WOSUID:

WOS:000366813200007
Contributors: Bousova, Iva; Skalova, Lenka; Soucek, Pavel; Matouskova, Petra
Source: Self-asserted source
Bousova via ResearcherID
grade
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Antioxidant, Pro-Oxidant and Other Biological Activities of Sesquiterpenes

Current Topics in Medicinal Chemistry
2014 | Journal article
WOSUID:

WOS:000347050000003
Contributors: Bartikova, Hana; Hanusova, Veronika; Skalova, Lenka; Ambroz, Martin; Bousova, Iva
Source: Self-asserted source
Bousova via ResearcherID

Effect of defined green tea extract in various dosage schemes on drug-metabolizing enzymes in mice in vivo

Journal of Functional Foods
2014 | Journal article
DOI: 10.1016/j.jff.2014.06.026
WOSUID:

WOS:000342034200035
Contributors: Matouskova, Petra; Bartikova, Hana; Bousova, Iva; Szotakova, Barbora; Martin, Jan; Skorkovska, Jana; Hanusova, Veronika; Tomankova, Veronika; Anzenbacherova, Eva; Liskova, Barbora et al.
Source: Self-asserted source
Bousova via ResearcherID
grade
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Effect of selected catechins on doxorubicin antiproliferative efficacy and hepatotoxicity in vitro

Acta Pharmaceutica
2014 | Journal article
DOI: 10.2478/acph-2014-0018
WOSUID:

WOS:000337705100005
Contributors: Rudolfova, Petra; Hanusova, Veronika; Skalova, Lenka; Bartikova, Hana; Matouskova, Petra; Bousova, Iva
Source: Self-asserted source
Bousova via ResearcherID
grade
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Effect of Standardized Cranberry Extract on the Activity and Expression of Selected Biotransformation Enzymes in Rat Liver and Intestine

Molecules
2014 | Journal article
DOI: 10.3390/molecules190914948
WOSUID:

WOS:000343093100122
Contributors: Bartikova, Hana; Bousova, Iva; Jedlickova, Pavla; Lnenickova, Katerina; Skalova, Lenka; Szotakova, Barbora
Source: Self-asserted source
Bousova via ResearcherID
grade
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In vitro anti-proliferative and anti-inflammatory activity of leaf and fruit extracts from Vaccinium bracteatum Thunb.

Pakistan Journal of Pharmaceutical Sciences
2014 | Journal article
WOSUID:

WOS:000346327000015
Contributors: Landa, Premysl; Skalova, Lenka; Bousova, Iva; Kutil, Zsofia; Langhansova, Lenka; Lou, Ji-Dong; Vanek, Tomas
Source: Self-asserted source
Bousova via ResearcherID

Reference Genes for Real-Time PCR Quantification of Messenger RNAs and MicroRNAs in Mouse Model of Obesity

Plos One
2014 | Journal article
DOI: 10.1371/journal.pone.0086033
WOSUID:

WOS:000330237000085
Contributors: Matouskova, Petra; Bartikova, Hana; Bousova, Iva; Hanusova, Veronika; Szotakova, Barbora; Skalova, Lenka
Source: Self-asserted source
Bousova via ResearcherID
grade
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Age-Related Changes in Hepatic Activity and Expression of Detoxification Enzymes in Male Rats

Biomed Research International
2013 | Journal article
DOI: 10.1155/2013/408573
WOSUID:

WOS:000322656400001
Contributors: Vyskocilova, Erika; Szotakova, Barbora; Skalova, Lenka; Bartikova, Hana; Hlavacova, Jitka; Bousova, Iva
Source: Self-asserted source
Bousova via ResearcherID
grade
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In vivo effect of oracin on doxorubicin reduction, biodistribution and efficacy in Ehrlich tumor bearing mice

Pharmacological Reports
2013 | Journal article
WOSUID:

WOS:000330270300019
Contributors: Hanusova, Veronika; Tomsik, Pavel; Kriesfalusyova, Lenka; Pakostova, Alena; Bousova, Iva; Skalova, Lenka
Source: Self-asserted source
Bousova via ResearcherID

Inhibitory effect of anthocyanidins on hepatic glutathione S-transferase, UDP-glucuronosyltransferase and carbonyl reductase activities in rat and human

Xenobiotica
2013 | Journal article
DOI: 10.3109/00498254.2012.756557
WOSUID:

WOS:000321466800004
Contributors: Szotakova, Barbora; Bartikova, Hana; Hlavacova, Jitka; Bousova, Iva; Skalova, Lenka
Source: Self-asserted source
Bousova via ResearcherID
grade
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Interaction of Anthocyanins with Drug-metabolizing and Antioxidant Enzymes

Current Medicinal Chemistry
2013 | Journal article
WOSUID:

WOS:000327445300003
Contributors: Bartikova, H.; Skalova, L.; Drsata, J.; Bousova, I.
Source: Self-asserted source
Bousova via ResearcherID

Inhibition and induction of glutathione S-transferases by flavonoids: possible pharmacological and toxicological consequences

Drug Metabolism Reviews
2012 | Journal article
DOI: 10.3109/03602532.2012.713969
WOSUID:

WOS:000312218600001
Contributors: Bousova, Iva; Skalova, Lenka
Source: Self-asserted source
Bousova via ResearcherID
grade
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Naturally occurring flavonoids as inhibitors of purified cytosolic glutathione S-transferase

Xenobiotica
2012 | Journal article
DOI: 10.3109/00498254.2012.670737
WOSUID:

WOS:000307301900006
Contributors: Bousova, Iva; Hajek, Jan; Drsata, Jaroslav; Skalova, Lenka
Source: Self-asserted source
Bousova via ResearcherID
grade
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The influence of oracin on reduction and toxicity of doxorubicin in hepatocytes and mammary epithelial cells MCF-10A

Xenobiotica
2012 | Journal article
DOI: 10.3109/00498254.2011.645517
WOSUID:

WOS:000303495300007
Contributors: Hanusova, V.; Bousova, I.; Pakostova, A.; Skalova, L.
Source: Self-asserted source
Bousova via ResearcherID
grade
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Antioxidant and prooxidant properties of flavonoids

Fitoterapia
2011 | Journal article
DOI: 10.1016/j.fitote.2011.01.018
WOSUID:

WOS:000291140800001
Contributors: Prochazkova, D.; Bousova, I.; Wilhelmova, N.
Source: Self-asserted source
Bousova via ResearcherID
grade
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Comparison of glycation of glutathione S-transferase by methylglyoxal, glucose or fructose

Molecular and Cellular Biochemistry
2011 | Journal article
DOI: 10.1007/s11010-011-0903-5
WOSUID:

WOS:000295941500035
Contributors: Bousova, Iva; Pruchova, Zuzana; Trnkova, Lucie; Drsata, Jaroslav
Source: Self-asserted source
Bousova via ResearcherID
grade
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Possibilities to increase the effectiveness of doxorubicin in cancer cells killing

Drug Metabolism Reviews
2011 | Journal article
DOI: 10.3109/03602532.2011.609174
WOSUID:

WOS:000296092500007
Contributors: Hanusova, Veronika; Bousova, Iva; Skalova, Lenka
Source: Self-asserted source
Bousova via ResearcherID
grade
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Study on the interaction of catechins with human serum albumin using spectroscopic and electrophoretic techniques

Journal of Molecular Structure
2011 | Journal article
DOI: 10.1016/j.molstruc.2010.11.001
WOSUID:

WOS:000286953100015
Contributors: Trnkova, Lucie; Bousova, Iva; Stankova, Veronika; Drsata, Jaroslav
Source: Self-asserted source
Bousova via ResearcherID
grade
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ANTIOXIDANTS AND ENVIRONMENTAL STRESS: SPECTROSCOPIC STUDY ON STABILITY OF NATURAL COMPOUNDS AND THEIR INTERACTION WITH A MOLECULE OF PROTEIN IN AN IN VITRO MODEL

Proceedings of Ecopole, 2009
2009 | Book chapter
WOSUID:

WOS:000269126300004
Contributors: Trnkova, Lucie; Bousova, Iva; Rysankova, Lucie; Vrabcova, Petra; Drsata, Jaroslav; Soc Ecol Chem & Engn
Source: Self-asserted source
Bousova via ResearcherID

Glycation of aspartate aminotransferase by methylglyoxal, effect of hydroxycitric and uric acid

Molecular and Cellular Biochemistry
2009 | Journal article
DOI: 10.1007/s11010-009-0161-y
WOSUID:

WOS:000271308000025
Contributors: Bousova, Iva; Bacilkova, Eliska; Dobrijevic, Sanja; Drsata, Jaroslav
Source: Self-asserted source
Bousova via ResearcherID
grade
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Oxidative stress parameters in different systemic rheumatic diseases

Journal of Pharmacy and Pharmacology
2006 | Journal article
DOI: 10.1211/jpp.58.7.0010
WOSUID:

WOS:000239136600010
Contributors: Firuzi, Omidreza; Fuksa, Leos; Spadaro, Chiara; Bousova, Iva; Riccieri, Valeria; Spadaro, Antonio; Petrucci, Rita; Marrosu, Giancarlo; Saso, Luciano
Source: Self-asserted source
Bousova via ResearcherID
grade
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Determination of quality of pyridoxal-5'-phosphate enzyme preparations by spectroscopic methods

Journal of Pharmaceutical and Biomedical Analysis
2005 | Journal article
DOI: 10.1016/j.jpba.2004.10.004
WOSUID:

WOS:000229599200049
Contributors: Drsata, J; Bousova, I; Malon, P
Source: Self-asserted source
Bousova via ResearcherID
grade
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Evaluation of in vitro effects of natural substances of plant origin using a model of protein glycoxidation

Journal of Pharmaceutical and Biomedical Analysis
2005 | Journal article
DOI: 10.1016/j.jpba.2004.10.014
WOSUID:

WOS:000229599200019
Contributors: Bousova, I; Martin, J; Jahodar, L; Dusek, J; Palicka, V; Drsata, J
Source: Self-asserted source
Bousova via ResearcherID
grade
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Glycation-induced inactivation of aspartate aminotransferase, effect of uric acid

Molecular and Cellular Biochemistry
2005 | Journal article
DOI: 10.1007/s11010-005-6933-0
WOSUID:

WOS:000232056600012
Contributors: Bousova, I; Bakala, H; Chudacek, R; Palicka, V; Drsata, J
Source: Self-asserted source
Bousova via ResearcherID
grade
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Enzyme activity and AGE formation in a model of AST glycoxidation by D-fructose in vitro.

Acta pharmaceutica (Zagreb, Croatia)
2005-03 | Journal article
PMID: 15907228
Contributors: Bousova I; Vukasović D; Juretić D; Palicka V; Drsata J
Source: Self-asserted source
Bousova via Europe PubMed Central
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