Personal information

Emails & domains

Verified email domains

Websites & social links

https://www.cipf.es/science/research/advanced-therapies/targeted-therapies-on-cancer-and-inflammation
https://research.uv.es/membdeath/index.php?id=Project&lang=en

Other IDs

Scopus Author ID: 25636245700
ResearcherID: L-4660-2014

Keywords

Apoptosis, Inflammation, Drug Development

Countries

Spain

Activities

Collapse all

Employment (3)

Universitat de València: Valencia, ES

2024 to present | Full-time trainee lecturer (Biochemistry and Molecular Biology)
Employment
Source: Self-asserted source
Mónica Sancho

Fundación de la Comunidad Valenciana Centro de Investigación Príncipe Felipe: Valencia, ES

2008 to present | Researcher (Targeted Therapies on Cancer and Inflammation)
Employment
Source: Self-asserted source
Mónica Sancho

Universitat de València: Valencia, ES

2020 to 2024 | Adjunct Professor (Biochemistry and Molecular Biology)
Employment
Source: Self-asserted source
Mónica Sancho

Education and qualifications (2)

Centre for Genomic Regulation: Barcelona, ES

2003 to 2008 | PhD (Gene Regulation)
Education
Source: Self-asserted source
Mónica Sancho

Pompeu Fabra University: Barcelona, ES

1998 to 2003 | Graduate in Biology
Education
Source: Self-asserted source
Mónica Sancho

Works (32)

Phenotyping of cancer-associated somatic mutations in the BCL2 transmembrane domain

Oncogenesis
2024 | Journal article
DOI: 10.1038/s41389-024-00516-3
EID:

2-s2.0-85191359496

Part of ISSN: 21579024
Contributors: Leiva, D.; Lucendo, E.; García-Jareño, A.B.; Sancho, M.; Orzáez, M.
Source: Self-asserted source
Mónica Sancho via Scopus - Elsevier
grade
Preferred source (of 2)‎

Targeted Delivery of the Pan-Inflammasome Inhibitor MM01 as an Alternative Approach to Acute Lung Injury Therapy.

Advanced healthcare materials
2023-07-29 | Journal article
DOI: 10.1002/adhm.202301577
PMID: 37515468
Contributors: García-Fernández A; Sancho M; Garrido E; Bisbal V; Sancenón F; Ramon Martinez-Manez; Orzáez M
Source: Self-asserted source
Mónica Sancho
grade
Preferred source (of 2)‎

Identification of NLRP3<sup>PYD</sup> Homo-Oligomerization Inhibitors with Anti-Inflammatory Activity

International Journal of Molecular Sciences
2022 | Journal article
DOI: 10.3390/ijms23031651
EID:

2-s2.0-85123711724

Part of ISSN: 14220067 16616596
Contributors: Ghafary, S.M.; Soriano-Teruel, P.M.; Lotfollahzadeh, S.; Sancho, M.; Serrano-Candelas, E.; Karami, F.; Barigye, S.J.; Fernández-Pérez, I.; Gozalbes, R.; Nikkhah, M. et al.
Source: Self-asserted source
Mónica Sancho via Scopus - Elsevier
grade
Preferred source (of 2)‎

Multiinflammasome inhibitors

Inflammasome Biology: Fundamentals, Role in Disease States, and Therapeutic Opportunities
2022 | Book chapter
Part of DOI: 10.1016/B978-0-323-91802-2.00038-4
EID:

2-s2.0-85199055109

Part of ISBN: 9780323918022 9780323972062
Contributors: Sancho, M.; Soriano-Teruel, P.M.; Orzáez, M.
Source: Self-asserted source
Mónica Sancho via Scopus - Elsevier

Understanding MCL1: from cellular function and regulation to pharmacological inhibition

The FEBS Journal
2022-10 | Journal article
DOI: 10.1111/febs.16136
Contributors: Mónica Sancho; Diego Leiva; Estefanía Lucendo; Mar Orzáez
Source: check_circle
Crossref
grade
Preferred source (of 3)‎

Nanodevices for the Efficient Codelivery of CRISPR-Cas9 Editing Machinery and an Entrapped Cargo: A Proposal for Dual Anti-Inflammatory Therapy

Pharmaceutics
2022-07-19 | Journal article
DOI: 10.3390/pharmaceutics14071495
Part of ISSN: 1999-4923
Contributors: Mónica Sancho; Gema Vivo-Llorca; Alba García-Fernández; Alicia Belén García-Jareño, Laura Ramírez-Jiménez, Eloísa Barber-Cano; José Ramón Murguía, Mar Orzáez, Félix Sancenón; Ramón Martínez-Máñez
Source: Self-asserted source
Mónica Sancho
grade
Preferred source (of 2)‎

BOK-MCL1 transmembrane interactions: a challenging target for cancer therapy

Molecular and Cellular Oncology
2021 | Journal article
DOI: 10.1080/23723556.2020.1859918
EID:

2-s2.0-85099373230

Part of ISSN: 23723556
Contributors: Sancho, M.; Orzáez, M.
Source: Self-asserted source
Mónica Sancho via Scopus - Elsevier
grade
Preferred source (of 2)‎

Identification of an ASC oligomerization inhibitor for the treatment of inflammatory diseases

Cell Death and Disease
2021 | Journal article
DOI: 10.1038/s41419-021-04420-1
EID:

2-s2.0-85121038833

Part of ISSN: 20414889
Contributors: Soriano-Teruel, P.M.; García‑Laínez, G.; Marco-Salvador, M.; Pardo, J.; Arias, M.; DeFord, C.; Merfort, I.; Vicent, M.J.; Pelegrín, P.; Sancho, M. et al.
Source: Self-asserted source
Mónica Sancho via Scopus - Elsevier
grade
Preferred source (of 2)‎

Targeted-lung delivery of dexamethasone using gated mesoporous silica nanoparticles. A new therapeutic approach for acute lung injury treatment

Journal of Controlled Release
2021-09 | Journal article
DOI: 10.1016/j.jconrel.2021.07.010
Part of ISSN: 0168-3659
Source: Self-asserted source
Mónica Sancho
grade
Preferred source (of 2)‎

Mcl-1 and Bok transmembrane domains: Unexpected players in the modulation of apoptosis

Proceedings of the National Academy of Sciences of the United States of America
2020 | Journal article
DOI: 10.1073/pnas.2008885117
EID:

2-s2.0-85096079914

Part of ISSN: 10916490 00278424
Contributors: Lucendo, E.; Sancho, M.; Lolicato, F.; Javanainen, M.; Kulig, W.; Leiva, D.; Duart, G.; Andreu-Fernández, V.; Mingarro, I.; Orzáez, M.
Source: Self-asserted source
Mónica Sancho via Scopus - Elsevier
grade
Preferred source (of 2)‎

Preclinical antitumor efficacy of senescence-inducing chemotherapy combined with a nanoSenolytic

Journal of Controlled Release
2020-07 | Journal article
DOI: 10.1016/j.jconrel.2020.04.045
Part of ISSN: 0168-3659
Source: Self-asserted source
Mónica Sancho
grade
Preferred source (of 2)‎

Erratum: Bax transmembrane domain interacts with prosurvival Bcl-2 proteins in biological membranes (Proceedings of the National Academy of Sciences of the United States of America (2017) 114:2 (310-315) DOI: 10.1073/pnas.1612322114)

Proceedings of the National Academy of Sciences of the United States of America
2017 | Journal article
DOI: 10.1073/pnas.1701233114
EID:

2-s2.0-85026617347

Part of ISSN: 10916490 00278424
Contributors: Andreu-Fernández, V.; Sancho, M.; Genovés, A.; Lucendo, E.; Todt, F.; Lauterwasser, J.; Funk, K.; Jahreis, G.; Pérez-Payá, E.; Mingarro, I. et al.
Source: Self-asserted source
Mónica Sancho via Scopus - Elsevier

Identification and validation of uterine stimulant methylergometrine as a potential inhibitor of caspase-1 activation

Apoptosis
2017-10 | Journal article
DOI: 10.1007/s10495-017-1405-z
Part of ISSN: 1360-8185
Part of ISSN: 1573-675X
Source: Self-asserted source
Mónica Sancho
grade
Preferred source (of 2)‎

Bax transmembrane domain interacts with prosurvival Bcl-2 proteins in biological membranes

Proceedings of the National Academy of Sciences
2017-01-10 | Journal article
DOI: 10.1073/pnas.1612322114
Part of ISSN: 0027-8424
Part of ISSN: 1091-6490
Source: Self-asserted source
Mónica Sancho
grade
Preferred source (of 2)‎

Apaf1 inhibition promotes cell recovery from apoptosis

Protein & Cell
2015-11 | Journal article
DOI: 10.1007/s13238-015-0200-2
Part of ISSN: 1674-800X
Part of ISSN: 1674-8018
Source: Self-asserted source
Mónica Sancho
grade
Preferred source (of 2)‎

Apaf-1 Inhibitors Protect from Unwanted Cell Death in In Vivo Models of Kidney Ischemia and Chemotherapy Induced Ototoxicity

PLoS ONE
2014-10-20 | Journal article
DOI: 10.1371/journal.pone.0110979
Part of ISSN: 1932-6203
Source: Self-asserted source
Mónica Sancho
grade
Preferred source (of 2)‎

Dynamics and dispensability of variant-specific histone H1 Lys-26/Ser-27 and Thr-165 post-translational modifications

FEBS Letters
2014-06-27 | Journal article
DOI: 10.1016/j.febslet.2014.05.035
Part of ISSN: 0014-5793
Source: Self-asserted source
Mónica Sancho
grade
Preferred source (of 2)‎

Role of CDK5/cyclin complexes in ischemia-induced death and survival of renal tubular cells

Cell Cycle
2014-05-15 | Journal article
DOI: 10.4161/cc.28628
Part of ISSN: 1538-4101
Part of ISSN: 1551-4005
Source: Self-asserted source
Mónica Sancho
grade
Preferred source (of 2)‎

Mapping of six somatic linker histone H1 variants in human breast cancer cells uncovers specific features of H1.2

Nucleic Acids Research
2014-04 | Journal article
DOI: 10.1093/nar/gku079
Part of ISSN: 1362-4962
Part of ISSN: 0305-1048
Source: Self-asserted source
Mónica Sancho
grade
Preferred source (of 2)‎

Inactivation of Apaf1 reduces the formation of mutant huntingtin-dependent aggregates and cell death

Neuroscience
2014-03 | Journal article
DOI: 10.1016/j.neuroscience.2013.12.062
Part of ISSN: 0306-4522
Source: Self-asserted source
Mónica Sancho
grade
Preferred source (of 2)‎

Altered Mitochondria Morphology and Cell Metabolism in Apaf1-Deficient Cells

PLoS ONE
2014-01-09 | Journal article
DOI: 10.1371/journal.pone.0084666
Part of ISSN: 1932-6203
Source: Self-asserted source
Mónica Sancho
grade
Preferred source (of 2)‎

Optimizing the control of apoptosis by amide/triazole isosteric substitution in a constrained peptoid

European Journal of Medicinal Chemistry
2013-05 | Journal article
DOI: 10.1016/j.ejmech.2013.03.004
Part of ISSN: 0223-5234
Source: Self-asserted source
Mónica Sancho
grade
Preferred source (of 2)‎

BH3-Mimetics- and Cisplatin-Induced Cell Death Proceeds through Different Pathways Depending on the Availability of Death-Related Cellular Components

PLoS ONE
2013-02-21 | Journal article
DOI: 10.1371/journal.pone.0056881
Part of ISSN: 1932-6203
Source: Self-asserted source
Mónica Sancho
grade
Preferred source (of 2)‎

A Polymeric Nanomedicine Diminishes Inflammatory Events in Renal Tubular Cells

PLoS ONE
2013-01-02 | Journal article
DOI: 10.1371/journal.pone.0051992
Part of ISSN: 1932-6203
Source: Self-asserted source
Mónica Sancho
grade
Preferred source (of 2)‎

Synthesis of enantiomerically pure perhydro-1,4-diazepine-2,5-dione and 1,4-piperazine-2,5-dione derivatives exhibiting potent activity as apoptosis inhibitors

Bioorganic & Medicinal Chemistry Letters
2012-12 | Journal article
DOI: 10.1016/j.bmcl.2012.09.078
Part of ISSN: 0960-894X
Source: Self-asserted source
Mónica Sancho
grade
Preferred source (of 2)‎

Intrinsic caspase-8 activation mediates sensitization of erlotinib-resistant tumor cells to erlotinib/cell-cycle inhibitors combination treatment

Cell Death & Disease
2012-10 | Journal article
DOI: 10.1038/cddis.2012.155
Part of ISSN: 2041-4889
Source: Self-asserted source
Mónica Sancho
grade
Preferred source (of 2)‎

Inhibition of Apaf-1 as a potential therapeutic strategy to improve corneal quality

Acta Ophthalmologica
2012-09 | Journal article
DOI: 10.1111/j.1755-3768.2012.3434.x
Part of ISSN: 1755-375X
Source: Self-asserted source
Mónica Sancho

Polypeptide Modulators of Caspase Recruitment Domain (CARD)-CARD-mediated Protein-Protein Interactions

Journal of Biological Chemistry
2011-12-30 | Journal article
DOI: 10.1074/jbc.m111.255364
Part of ISSN: 0021-9258
Part of ISSN: 1083-351X
Source: Self-asserted source
Mónica Sancho
grade
Preferred source (of 2)‎

Minocycline inhibits cell death and decreases mutant Huntingtin aggregation by targeting Apaf-1

Human Molecular Genetics
2011-09-15 | Journal article
DOI: 10.1093/hmg/ddr271
Part of ISSN: 1460-2083
Part of ISSN: 0964-6906
Source: Self-asserted source
Mónica Sancho
grade
Preferred source (of 2)‎

Characterization of dequalinium as a XIAP antagonist that targets the BIR2 domain

Apoptosis
2011-05 | Journal article
DOI: 10.1007/s10495-011-0582-4
Part of ISSN: 1360-8185
Part of ISSN: 1573-675X
Source: Self-asserted source
Mónica Sancho
grade
Preferred source (of 2)‎

Molecules that bind a central protein component of the apoptosome, Apaf-1, and modulate its activity

Apoptosome: An Up-and-coming Therapeutical Tool
2010 | Book chapter
Part of DOI: 10.1007/978-90-481-3415-1_4
EID:

2-s2.0-84910074223

Part of ISBN: 9789048134151 9789048134144
Contributors: Mondragón, L.; Orzáez, M.; Gortat, A.; Sancho, M.; Messeguer, A.; Vicent, M.J.; Pérez-Payá, E.
Source: Self-asserted source
Mónica Sancho via Scopus - Elsevier

Depletion of Human Histone H1 Variants Uncovers Specific Roles in Gene Expression and Cell Growth

PLoS Genetics
2008-10-17 | Journal article
DOI: 10.1371/journal.pgen.1000227
Part of ISSN: 1553-7404
Source: Self-asserted source
Mónica Sancho
grade
Preferred source (of 2)‎

Peer review (2 reviews for 2 publications/grants)

Review activity for Free radical biology & medicine. (1)
Review activity for Materials today bio. (1)
How many people are using ORCID?