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Duke University School of Medicine: Durham, NC, US

2013-04-01 to present | Professor of Anesthesiology, Critical Care, and Surgery (Cardiothoracic) (Anesthesiology)
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Jerrold H Levy

Works (50 of 72)

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Page 1 of 2

Pharmacologic Approaches to Bleeding

2025 | Book chapter
DOI: 10.1016/B978-0-323-96014-4.00064-1
Contributors: Jerrold H. Levy
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Mitochondrial dysfunction is a major cause of thromboinflammation and inflammatory cell death in critical illnesses

Inflammation Research
2025-12 | Journal article
DOI: 10.1007/s00011-025-01994-w
Contributors: Toshiaki Iba; Julie Helms; Cheryl L. Maier; Ricard Ferrer; Jerrold H. Levy
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Limitations of current risk models for perioperative bleeding and transfusion in cardiac surgery: Are new strategies needed?

Transfusion
2025-04 | Journal article
DOI: 10.1111/trf.18215
Contributors: Gabor Erdoes; Andreas Koster; Michael Nagler; Jerrold H. Levy
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Reversal of direct oral anticoagulants: guidance from the SSC of the ISTH: reply

Journal of Thrombosis and Haemostasis
2025-03 | Journal article
DOI: 10.1016/j.jtha.2025.03.010
Contributors: Jerrold H. Levy; Joseph R. Shaw; Jean M. Connors; James Douketis; Jeffrey I. Weitz
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ECMO Induced Coagulopathy: Strategic Initiatives for Research and Clinical Practice. A Workshop Report of the NHLBI

Blood Vessels, Thrombosis & Hemostasis
2025-02 | Journal article
DOI: 10.1016/j.bvth.2025.100064
Contributors: Jerrold H Levy; Peta M A Alexander; Alisa S. Wolberg; Owen J.T. McCarty; Anthony E Pusateri; Raquel R Bartz; Wolfgang Bergmeier; Mitchell J Cohen; Jean M Connors; James H Morrissey et al.
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Results of an international survey on the management of therapeutic intensity unfractionated heparin: communication from the SSCs of the ISTH

Journal of Thrombosis and Haemostasis
2025-02 | Journal article
DOI: 10.1016/j.jtha.2025.02.012
Contributors: Isabelle Gouin-Thibault; Lana A. Castellucci; Jean M. Connors; Michael Hardy; Alexandre Mansour; Virginie Siguret; Corinne Frere; Jerrold H. Levy; Adam Cuker; Thomas Lecompte et al.
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The role of viscoelastic tests in the diagnosis of sepsis-induced coagulopathy (SIC)

Annals of Intensive Care
2025-01-28 | Journal article
DOI: 10.1186/s13613-025-01442-2
Contributors: Toshiaki Iba; Julie Helms; Jerrold H. Levy
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Impact of hyper- and hypothermia on cellular and whole-body physiology

Journal of Intensive Care
2025-01-13 | Journal article
DOI: 10.1186/s40560-024-00774-8
Contributors: Toshiaki Iba; Yutaka Kondo; Cheryl L. Maier; Julie Helms; Ricard Ferrer; Jerrold H. Levy
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Endothelial Glycocalyx Protection in Sepsis

Juntendo Medical Journal
2024 | Journal article
DOI: 10.14789/jmj.JMJ23-0041-P
Contributors: JERROLD H Levy; TOSHIAKI Iba
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Fibrinolytic Changes in Critical Illnesses: Is Fibrinolysis Shutdown a Specific Concept?

Juntendo Medical Journal
2024 | Journal article
DOI: 10.14789/ejmj.JMJ24-0035-P
Contributors: JERROLD H. LEVY; TOSHIAKI IBA
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Why is DIC a Rare Diagnosis in the 21<sup>st</sup> Century?

Juntendo Medical Journal
2024 | Journal article
DOI: 10.14789/jmj.JMJ24-0005-P
Contributors: JECKO THACHIL; TOSHIAKI IBA; ECATERINA SCARLATESCU; JERROLD H. LEVY
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Reply to the comments on “Four years into the pandemic, managing COVID-19 patients with acute coagulopathy: what have we learned?” from Wada et al.

Journal of Thrombosis and Haemostasis
2024-12 | Journal article
DOI: 10.1016/j.jtha.2024.09.010
Contributors: Toshiaki Iba; Jerrold H. Levy
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Heparins May Not Be the Optimal Anticoagulants for Sepsis and Sepsis-Associated Disseminated Intravascular Coagulation

Seminars in Thrombosis and Hemostasis
2024-10 | Journal article
DOI: 10.1055/s-0044-1786754
Contributors: Toshiaki Iba; Julie Helms; Takaaki Totoki; Jerrold H. Levy
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Reversal of direct oral anticoagulants: guidance from the SSC of the ISTH

Journal of Thrombosis and Haemostasis
2024-10 | Journal article
DOI: 10.1016/j.jtha.2024.07.009
Contributors: Jerrold H. Levy; Joseph R. Shaw; Lana A. Castellucci; Jean M. Connors; James Douketis; Edelgard Lindhoff-Last; Bianca Rocca; Charles Marc Samama; Deborah Siegal; Jeffrey I. Weitz
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Autophagy and autophagic cell death in sepsis: friend or foe?

Journal of Intensive Care
2024-10-25 | Journal article
DOI: 10.1186/s40560-024-00754-y
Contributors: Toshiaki Iba; Julie Helms; Cheryl L. Maier; Ricard Ferrer; Jerrold H. Levy
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Acquired von Willebrand syndrome during extracorporeal membrane oxygenation support: a comprehensive review of current evidence: communication from the ISTH SSC on perioperative and critical care thrombosis and hemostasis

Journal of Thrombosis and Haemostasis
2024-09 | Journal article
DOI: 10.1016/j.jtha.2024.06.007
Contributors: Corinne Frere; Michael Mazzeffi; Cheryl L. Maier; Julie Helms; Marie E. Steiner; Bruce A. Sullenger; Kenichi A. Tanaka; Jean M. Connors; Jerrold H. Levy
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Deranged Balance of Hemostasis and Fibrinolysis in Disseminated Intravascular Coagulation: Assessment and Relevance in Different Clinical Settings

Anesthesiology
2024-09 | Journal article
DOI: 10.1097/ALN.0000000000005023
Contributors: Ecaterina Scarlatescu; Toshiaki Iba; Cheryl L. Maier; Hunter Moore; Maha Othman; Jean Marie Connors; Jerrold H. Levy
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Sepsis-induced coagulopathy (SIC) in the management of sepsis

Annals of Intensive Care
2024-09-20 | Journal article
DOI: 10.1186/s13613-024-01380-5
Contributors: Toshiaki Iba; Julie Helms; Jerrold H. Levy
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Protocol for a phase 3, randomised, active-control study of four-factor prothrombin complex concentrate versus frozen plasma in bleeding adult cardiac surgery patients requiring coagulation factor replacement: the LEX-211 (FARES-II) trial

BMJ Open
2024-08 | Journal article
DOI: 10.1136/bmjopen-2024-091381
Contributors: Keyvan Karkouti; Jeannie Callum; Justyna Bartoszko; Cristina Solomon; Sigurd Knaub; Jerrold H Levy; Kenichi A Tanaka
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Rethinking Coagulation Activation during Extracorporeal Membrane Oxygenation: Insights from the Case of Mr. Hageman

Anesthesiology
2024-07 | Journal article
DOI: 10.1097/ALN.0000000000005003
Contributors: Kenichi A. Tanaka; Michael A. Mazzeffi; Jerrold H. Levy
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“Finding a common definition of heparin resistance in adult cardiac surgery: Communication from the ISTH SSC Subcommittee on Perioperative and Critical Care Thrombosis and Hemostasis”: reply

Journal of Thrombosis and Haemostasis
2024-07 | Journal article
DOI: 10.1016/j.jtha.2024.04.014
Contributors: Roman M. Sniecinski; Jerrold H. Levy
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Antithrombin Deficiency during Venoarterial Extracorporeal Membrane Oxygenation: Extremely Common, but Does It Matter?

Anesthesiology
2024-06 | Journal article
DOI: 10.1097/ALN.0000000000004948
Contributors: Michael Mazzeffi; Jerrold H. Levy
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Antithrombin supplementation attenuates heparin resistance in plasma spiked with Gla-domainless factor Xa S195A in vitro

British Journal of Anaesthesia
2024-06 | Journal article
DOI: 10.1016/j.bja.2024.02.027
Contributors: Yuko Mishima; Amir L. Butt; Kofi B. Vandyck; Jerrold H. Levy; Kenneth E. Stewart; Kenichi A. Tanaka
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Four years into the pandemic, managing COVID-19 patients with acute coagulopathy: what have we learned?

Journal of Thrombosis and Haemostasis
2024-06 | Journal article
DOI: 10.1016/j.jtha.2024.02.013
Contributors: Toshiaki Iba; Jerrold H. Levy; Cheryl L. Maier; Jean M. Connors; Marcel Levi
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The role of thromboinflammation in acute kidney injury among patients with septic coagulopathy

Journal of Thrombosis and Haemostasis
2024-06 | Journal article
DOI: 10.1016/j.jtha.2024.02.006
Contributors: Toshiaki Iba; Julie Helms; Cheryl L. Maier; Marcel Levi; Ecaterina Scarlatescu; Jerrold H. Levy
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What Role Does Microthrombosis Play in Long COVID?

Seminars in Thrombosis and Hemostasis
2024-06 | Journal article
DOI: 10.1055/s-0043-1774795
Contributors: Toshiaki Iba; Jean M. Connors; Jerrold H. Levy
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Determining prognostic indicator for anticoagulant therapy in sepsis-induced disseminated intravascular coagulation

Journal of Intensive Care
2024-06-24 | Journal article
DOI: 10.1186/s40560-024-00739-x
Contributors: Toshiaki Iba; Kazuma Yamakawa; Yuki Shiko; Ryo Hisamune; Tomoki Tanigawa; Julie Helms; Jerrold H. Levy
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Finding a common definition of heparin resistance in adult cardiac surgery: communication from the ISTH SSC subcommittee on perioperative and critical care thrombosis and hemostasis

Journal of Thrombosis and Haemostasis
2024-04 | Journal article
DOI: 10.1016/j.jtha.2024.01.001
Contributors: Jerrold H. Levy; Roman M. Sniecinski; Cheryl L. Maier; George J. Despotis; Kamrouz Ghadimi; Julie Helms; Marco Ranucci; Marie E. Steiner; Kenichi A. Tanaka; Jean M. Connors
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Managing sepsis and septic shock in an endothelial glycocalyx-friendly way: from the viewpoint of surviving sepsis campaign guidelines

Annals of Intensive Care
2024-04-24 | Journal article
DOI: 10.1186/s13613-024-01301-6
Contributors: Toshiaki Iba; Cheryl L. Maier; Julie Helms; Ricard Ferrer; Jecko Thachil; Jerrold H. Levy
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Andexanet alfa or prothrombin complex concentrate for acute reversal of oral factor Xa inhibitors: monitoring of antidote effects

British Journal of Anaesthesia
2024-02 | Journal article
DOI: 10.1016/j.bja.2023.11.028
Contributors: Kenichi A. Tanaka; Jerrold H. Levy
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Reply to the letter to the editor regarding “Defining heparin resistance: communication from the ISTH SSC Subcommittee of Perioperative and Critical Care Thrombosis and Hemostasis”

Journal of Thrombosis and Haemostasis
2024-02 | Journal article
DOI: 10.1016/j.jtha.2023.11.004
Contributors: Jerrold H. Levy; Roman M. Sniecinski
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Optimizing Anticoagulation for Venovenous Extracorporeal Membrane Oxygenation: Finding the Right Balance

American Journal of Respiratory and Critical Care Medicine
2024-02-15 | Journal article
DOI: 10.1164/rccm.202311-2061ED
Contributors: Christiaan L. Meuwese; Jerrold H. Levy
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Droxidopa or Atomoxetine for Refractory Hypotension in Critically Ill Cardiothoracic Surgery Patients

Journal of Cardiothoracic and Vascular Anesthesia
2024-01 | Journal article
DOI: 10.1053/j.jvca.2023.09.023
Contributors: Julia K. Lessing; Shawn J. Kram; Jerrold H. Levy; Loreta M. Grecu; Jason N. Katz
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Thromboinflammation in acute injury: infections, heatstroke, and trauma

Journal of Thrombosis and Haemostasis
2024-01 | Journal article
DOI: 10.1016/j.jtha.2023.07.020
Contributors: Toshiaki Iba; Julie Helms; Marcel Levi; Jerrold H. Levy
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Defining heparin resistance: communication from the ISTH SSC Subcommittee of Perioperative and Critical Care Thrombosis and Hemostasis

Journal of Thrombosis and Haemostasis
2023-12 | Journal article
DOI: 10.1016/j.jtha.2023.08.013
Contributors: Jerrold H. Levy; Roman M. Sniecinski; Bianca Rocca; Kamrouz Ghadimi; James Douketis; Corinne Frere; Julie Helms; Toshiaki Iba; Andreas Koster; Tara K. Lech et al.
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Mechanisms and management of the coagulopathy of trauma and sepsis: trauma-induced coagulopathy, sepsis-induced coagulopathy, and disseminated intravascular coagulation

Journal of Thrombosis and Haemostasis
2023-12 | Journal article
DOI: 10.1016/j.jtha.2023.05.028
Contributors: Toshiaki Iba; Julie Helms; Matthew D. Neal; Jerrold H. Levy
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Risk stratification utilizing sequential organ failure assessment (SOFA) score, antithrombin activity, and demographic data in sepsis-associated disseminated intravascular coagulation (DIC)

Scientific Reports
2023-12-15 | Journal article
DOI: 10.1038/s41598-023-49855-y
Contributors: Toshiaki Iba; Cheryl L. Maier; Tomoki Tanigawa; Jerrold H. Levy
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The antithrombin activity recovery after substitution therapy is associated with improved 28-day mortality in patients with sepsis-associated disseminated intravascular coagulation

Thrombosis Journal
2023-11-02 | Journal article
DOI: 10.1186/s12959-023-00556-6
Contributors: Toshiaki Iba; Tomoki Tanigawa; Hideo Wada; Jerrold H. Levy
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Thrombin generation, bleeding and hemostasis in humans: Protocol for a scoping review of the literature

PLOS ONE
2023-11-01 | Journal article
DOI: 10.1371/journal.pone.0293632
Contributors: Joseph R. Shaw; Alessio Branchini; Tyler James; Jonathan Douxfils; Yesim Dargaud; Jerrold H. Levy; Herm Jan M. Brinkman; Risa Shorr; Deborah Siegal; Lana A. Castellucci et al.
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Inhaled Epoprostenol Compared With Nitric Oxide for Right Ventricular Support After Major Cardiac Surgery

Circulation
2023-10-24 | Journal article
DOI: 10.1161/CIRCULATIONAHA.122.062464
Contributors: Kamrouz Ghadimi; Jhaymie L. Cappiello; Mary Cooter Wright; Jerrold H. Levy; Benjamin S. Bryner; Adam D. DeVore; Jacob N. Schroder; Chetan B. Patel; Sudarshan Rajagopal; Svati H. Shah et al.
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Coagulation support during perioperative bleeding management

Intensive Care Medicine
2023-09 | Journal article
DOI: 10.1007/s00134-023-07089-6
Contributors: Derek J. B. Kleinveld; Nicola Curry; Jerrold H. Levy
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Perioperative Anaphylaxis: Reply

Anesthesiology
2023-09 | Journal article
DOI: 10.1097/ALN.0000000000004598
Contributors: Charles Tacquard; Toshiaki Iba; Jerrold H. Levy
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A commentary on “Thromboinflammation in long COVID – the elusive key to post-infection sequelae?”

Journal of Thrombosis and Haemostasis
2023-08 | Journal article
DOI: 10.1016/j.jtha.2023.05.018
Contributors: Toshiaki Iba; Jerrold H. Levy
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Resistance to unfractionated heparin in the ICU: evaluation and management options

Intensive Care Medicine
2023-08 | Journal article
DOI: 10.1007/s00134-023-07103-x
Contributors: Jerrold H. Levy; Corinne Frere; Andreas Koster
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Management of patients on antithrombotic therapy with severe infections: a joint clinical consensus statement of the ESC Working Group on Thrombosis, the ESC Working Group on Atherosclerosis and Vascular Biology, and the International Society on Thrombosis and Haemostasis

European Heart Journal
2023-08-22 | Journal article
DOI: 10.1093/eurheartj/ehad388
Contributors: Bruna Gigante; Jerrold H Levy; Eric van Gorp; Alessandro Bartoloni; Marie-Luce Bochaton-Piallat; Magnus Bäck; Hugo ten Cate; Christina Christersson; José Luis Ferreiro; Tobias Geisler et al.
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What’s fishy about protamine? Clinical use, adverse reactions, and potential alternatives

Journal of Thrombosis and Haemostasis
2023-07 | Journal article
DOI: 10.1016/j.jtha.2023.04.005
Contributors: Jerrold H. Levy; Kamrouz Ghadimi; Jayachandran N. Kizhakkedathu; Toshiaki Iba
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“Communication from the Scientific and Standardization Committee of the International Society on Thrombosis and Hemostasis on sepsis-induced coagulopathy in the management of sepsis”: reply

Journal of Thrombosis and Haemostasis
2023-06 | Journal article
DOI: 10.1016/j.jtha.2023.02.025
Contributors: Toshiaki Iba; Marcel Levi; Jerrold H. Levy
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The pathophysiology, diagnosis, and management of sepsis-associated disseminated intravascular coagulation

Journal of Intensive Care
2023-05-23 | Journal article
DOI: 10.1186/s40560-023-00672-5
Contributors: Toshiaki Iba; Julie Helms; Jean Marie Connors; Jerrold H. Levy
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In Vitro Treatment of Extracorporeal Membrane Oxygenation Coagulopathy with Recombinant von Willebrand Factor or Lyophilized Platelets

Journal of Cardiothoracic and Vascular Anesthesia
2023-04 | Journal article
DOI: 10.1053/j.jvca.2022.12.028
Contributors: Michael Mazzeffi; Alberto Gonzalez-Almada; Richard Wargowsky; Lucas Ting; Keith Moskowitz; Max Hockstein; Danielle Davison; Jerrold H. Levy; Kenichi A. Tanaka
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Communication from the Scientific Standardization Committees of the International Society on Thrombosis and Haemostasis on vascular endothelium-related biomarkers in disseminated intravascular coagulation

Journal of Thrombosis and Haemostasis
2023-03 | Journal article
DOI: 10.1016/j.jtha.2022.11.032
Contributors: Toshiaki Iba; Jerrold H. Levy; Jecko Thachil; Sophie Susen; Marcel Levi; Ecaterina Scarlatescu
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