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Loop profile: 926853
Scopus Author ID: 25723735100

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Works (32)

RGG peptide induces the disassembly of disease-relevant FUS and TDP43 condensates

2025-03-19 | Preprint
DOI: 10.1101/2025.03.19.643735
Contributors: Mani Garg; Nayana Vinayan; Poulami Ghosh; Kesavardhana Sannula; Purusharth I Rajyaguru
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Should scientists teach: Balancing research and teaching

BBA Advances
2024 | Journal article
DOI: 10.1016/j.bbadva.2024.100122
Contributors: Purusharth I Rajyaguru
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Tdh3 and Rom2 are functional modulators of a conserved condensate-resident RNA-binding protein, Scd6, in Saccharomyces cerevisiae

GENETICS
2024-10-07 | Journal article
DOI: 10.1093/genetics/iyae127
Contributors: Chitra Togra; Riya Dhage; Purusharth I Rajyaguru; E Tran
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RGG-motif protein Scd6 affects oxidative stress response by regulating Cytosolic caTalase T1 (Ctt1)

2023-09-05 | Preprint
DOI: 10.1101/2023.09.05.556329
Contributors: Sweta Tiwari; Sudharshan Sj; Purusharth I Rajyaguru
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RGG motif-containing Scd6/LSM14A proteins regulate the translation of specific mRNAs in response to hydroxyurea-induced genotoxic stress

2022-07-13 | Preprint
DOI: 10.1101/2022.07.12.499753
Contributors: Gayatri Mohanan; Raju Roy; Hélène Malka-Mahieu; Swati Lamba; Lucilla Fabbri; Anusmita Biswas; Sylvain Martineau; Céline M. Labbé; Stéphan Vagner; Purusharth I Rajyaguru
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Low complexity RGG-motif sequence is required for Processing body (P-body) disassembly

Nature Communications
2022-04-19 | Journal article
DOI: 10.1038/s41467-022-29715-5
Contributors: Raju Roy; Gitartha Das; Ishwarya Achappa Kuttanda; Nupur Bhatter; Purusharth I. Rajyaguru
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Editorial: RNA-Protein Interactions in mRNA Translation and Decay

Frontiers in Molecular Biosciences
2021 | Journal article
DOI: 10.3389/fmolb.2021.803063
EID:

2-s2.0-85120859084

Part of ISSN: 2296889X
Contributors: Rajyaguru, P.I.; Vagner, S.; Evguenieva-Hackenberg, E.
Source: Self-asserted source
PURUSHARTH RAJYAGURU via Scopus - Elsevier

Genotoxic stress response: What is the role of cytoplasmic mRNA fate?

BioEssays
2021 | Journal article
DOI: 10.1002/bies.202000311
EID:

2-s2.0-85107285297

Part of ISSN: 15211878 02659247
Contributors: Mohanan, G.; Das, A.; Rajyaguru, P.I.
Source: Self-asserted source
PURUSHARTH RAJYAGURU via Scopus - Elsevier

RGG-motif containing mRNA export factor Gbp2 acts as a translation repressor

RNA Biology
2021-12-02 | Journal article
DOI: 10.1080/15476286.2021.1910403
Contributors: Gopalakrishna Poornima; Gaurav Srivastava; Brinta Roy; Ishwarya Achappa Kuttanda; Iladeiti Kurbah; Purusharth I. Rajyaguru
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Exploring the role of RRM domains and conserved aromatic residues in RGG motif  of eIF4G-binding translation repressor protein Sbp1

Wellcome Open Research
2021-09-17 | Journal article
DOI: 10.12688/wellcomeopenres.14709.3
Contributors: Nupur Bhatter; Rajan Iyyappan; Gayatri Mohanan; Purusharth I Rajyaguru
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Arginine methylation and cytoplasmic mRNA fate: An exciting new partnership

Yeast
2021-08 | Journal article
DOI: 10.1002/yea.3653
Contributors: Sabnam Parbin; Subha Damodharan; Purusharth I. Rajyaguru
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RGG-motif protein Sbp1 is required for Processing body (P-body) disassembly

2021-02-23 | Preprint
DOI: 10.1101/2021.02.23.432385
Contributors: Raju Roy; Ishwarya Achappa Kuttanda; Nupur Bhatter; Purusharth I Rajyaguru
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DEKTV and YVG motifs in the Lsm domain are important for the activity of Scd6, a conserved translation repressor protein

Biochimica et Biophysica Acta - Gene Regulatory Mechanisms
2020 | Journal article
DOI: 10.1016/j.bbagrm.2019.194474
EID:

2-s2.0-85078618424

Part of ISSN: 18764320 18749399
Contributors: Parbin, S.; Mohanan, G.; Gole, S.; Joshi, D.; Bhar, M.; Rajyaguru, P.I.
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PURUSHARTH RAJYAGURU via Scopus - Elsevier

Experiences of a New Teacher

Resonance
2020 | Journal article
DOI: 10.1007/s12045-020-1041-8
EID:

2-s2.0-85093842361

Part of ISSN: 0973712X 09718044
Contributors: Rajyaguru, P.I.
Source: Self-asserted source
PURUSHARTH RAJYAGURU via Scopus - Elsevier

Elucidation of the RNA-granule inducing sodium azide stress response through transcriptome analysis.

Genomics
2020-05 | Journal article
DOI: 10.1016/j.ygeno.2020.05.001
PMID: 32437849
Contributors: Garg M; Poornima G; Rajyaguru PI
Source: Self-asserted source
PURUSHARTH RAJYAGURU via Europe PubMed Central
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PSP2, a gene encoding RGG-motif protein, is a novel suppressor of clathrin heavy chain deficiency

2020-03-12 | Preprint
DOI: 10.1101/2020.03.11.986810
Contributors: Debadrita Roy; Mani Garg; Purusharth I Rajyaguru
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Exploring the role of RRM domains and conserved aromatic residues in RGG motif  of eIF4G-binding translation repressor protein Sbp1

Wellcome Open Research
2020-02-06 | Journal article
DOI: 10.12688/wellcomeopenres.14709.2
Contributors: Nupur Bhatter; Rajan Iyyappan; Purusharth I Rajyaguru
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PSP2 , a gene encoding RGG-motif protein, is a novel suppressor of clathrin heavy chain deficiency

ResearchSquare
2019 | Other
DOI: 10.21203/rs.2.17572
EID:

2-s2.0-85132134077
Contributors: Roy, D.; Garg, M.; Rajyaguru, P.I.
Source: Self-asserted source
PURUSHARTH RAJYAGURU via Scopus - Elsevier

RGG-motif self-association regulates eIF4G-binding translation repressor protein Scd6

RNA Biology
2019 | Journal article
DOI: 10.1080/15476286.2019.1621623
EID:

2-s2.0-85067694073

Part of ISSN: 15558584 15476286
Contributors: Poornima, G.; Mythili, R.; Nag, P.; Parbin, S.; Verma, P.K.; Hussain, T.; Rajyaguru, P.I.
Source: Self-asserted source
PURUSHARTH RAJYAGURU via Scopus - Elsevier

PSP2 , a gene encoding RGG-motif protein, is a novel suppressor of clathrin heavy chain deficiency

2019-11-20 | Other
DOI: 10.21203/rs.2.17572/v1
Contributors: Debadrita Roy; Mani Garg; Purusharth I Rajyaguru
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Arginine methylation augments Sbp1 function in translation repression and decapping.

The FEBS journal
2019-09 | Journal article
DOI: 10.1111/febs.15057
PMID: 31495062
Contributors: Bhatter N; Roy R; Shah S; Sastry SP; Parbin S; Iyappan R; Kankaria S; Rajyaguru PI
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PURUSHARTH RAJYAGURU via Europe PubMed Central
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Giardia lamblia Hsp90 pre-mRNAs undergo self-splicing to generate mature RNA in an in vitro trans-splicing reaction.

FEBS letters
2019-01 | Journal article
DOI: 10.1002/1873-3468.13324
PMID: 30604864
Contributors: Iyer V; Chettiar ST; Grover M; Rajyaguru P; Nageshan RK; Tatu U
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PURUSHARTH RAJYAGURU via Europe PubMed Central
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Stress granules and p-bodies: An insight into mRNA translational control and decay

Proceedings of the Indian National Science Academy
2018 | Journal article
EID:

2-s2.0-85050483282

Part of ISSN: 03700046
Contributors: Roy, R.; Rajyaguru, P.I.
Source: Self-asserted source
PURUSHARTH RAJYAGURU via Scopus - Elsevier

Suppressor of clathrin deficiency (Scd6)—An emerging RGG-motif translation repressor

Wiley Interdisciplinary Reviews: RNA
2018 | Journal article
DOI: 10.1002/wrna.1479
EID:

2-s2.0-85047658451

Part of ISSN: 17577012 17577004
Contributors: Roy, D.; Rajyaguru, P.I.
Source: Self-asserted source
PURUSHARTH RAJYAGURU via Scopus - Elsevier

Arginine methylation promotes translation repression activity of eIF4G-binding protein, Scd6.

Nucleic acids research
2016-09 | Journal article
DOI: 10.1093/nar/gkw762
PMID: 27613419
PMC: PMC5100564
Contributors: Poornima G; Shah S; Vignesh V; Parker R; Rajyaguru PI
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PURUSHARTH RAJYAGURU via Europe PubMed Central
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RGG motif proteins: modulators of mRNA functional states.

Cell cycle (Georgetown, Tex.)
2012-07 | Journal article
DOI: 10.4161/cc.20716
PMID: 22767211
PMC: PMC3873214
Contributors: Rajyaguru P; Parker R
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PURUSHARTH RAJYAGURU via Europe PubMed Central
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Scd6 targets eIF4G to repress translation: RGG motif proteins as a class of eIF4G-binding proteins.

Molecular cell
2012-01 | Journal article
DOI: 10.1016/j.molcel.2011.11.026
PMID: 22284680
PMC: PMC3277450
Contributors: Rajyaguru P; She M; Parker R
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PURUSHARTH RAJYAGURU via Europe PubMed Central
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rnr gene from the antarctic bacterium Pseudomonas syringae Lz4W, encoding a psychrophilic RNase R.

Applied and environmental microbiology
2011-09 | Journal article
DOI: 10.1128/AEM.05683-11
PMID: 21926201
PMC: PMC3208988
Contributors: Sulthana S; Rajyaguru PI; Mittal P; Ray MK
Source: Self-asserted source
PURUSHARTH RAJYAGURU via Europe PubMed Central
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Decapping activators in Saccharomyces cerevisiae act by multiple mechanisms.

Molecular cell
2010-09 | Journal article
DOI: 10.1016/j.molcel.2010.08.025
PMID: 20832728
PMC: PMC2946179
Contributors: Nissan T; Rajyaguru P; She M; Song H; Parker R
Source: Self-asserted source
PURUSHARTH RAJYAGURU via Europe PubMed Central
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CGH-1 and the control of maternal mRNAs.

Trends in cell biology
2008-12 | Journal article
DOI: 10.1016/j.tcb.2008.11.001
PMID: 19062290
Contributors: Rajyaguru P; Parker R
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PURUSHARTH RAJYAGURU via Europe PubMed Central
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Exoribonuclease R in Pseudomonas syringae is essential for growth at low temperature and plays a novel role in the 3' end processing of 16 and 5 S ribosomal RNA.

The Journal of biological chemistry
2007-04 | Journal article
DOI: 10.1074/jbc.m605588200
PMID: 17405875
Contributors: Purusharth RI; Madhuri B; Ray MK
Source: Self-asserted source
PURUSHARTH RAJYAGURU via Europe PubMed Central

Exoribonuclease R interacts with endoribonuclease E and an RNA helicase in the psychrotrophic bacterium Pseudomonas syringae Lz4W.

The Journal of biological chemistry
2005-02 | Journal article
DOI: 10.1074/jbc.m413507200
PMID: 15705581
Contributors: Purusharth RI; Klein F; Sulthana S; Jäger S; Jagannadham MV; Evguenieva-Hackenberg E; Ray MK; Klug G
Source: Self-asserted source
PURUSHARTH RAJYAGURU via Europe PubMed Central
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