Personal information

DNA replication stress, Genome Instability, Cancer chemotherapeutics, Oncogene-induced replication stress
Switzerland

Activities

Employment (9)

University of Zurich: Zurich, CH

2023-11-01 to present | Full Professor (Institute of Molecular Cancer Research)
Employment
Source: Self-asserted source
Massimo Lopes

University of Zurich: Zurich, CH

2017-02-01 to present | Board of Directors (Institute of Molecular Cancer Research)
Employment
Source: Self-asserted source
Massimo Lopes

University of Zurich: Zurich, CH

2015-03-01 to 2023-10-31 | Associate Professor (Institute of Molecular Cancer Research)
Employment
Source: Self-asserted source
Massimo Lopes

University of Zurich: Zurich, CH

2019-04-01 to 2021-03-31 | Chair of the Institute (Institute of Molecular Cancer Research)
Employment
Source: Self-asserted source
Massimo Lopes

University of Zurich: Zurich, CH

2007-05-01 to 2015-02-28 | Assistant Professor (Institute of Molecular Cancer Research)
Employment
Source: Self-asserted source
Massimo Lopes

University of Zurich: Zurich, CH

2005-07-01 to 2007-04-30 | Postdoctoral assistant (Institute of Molecular Cancer Research)
Employment
Source: Self-asserted source
Massimo Lopes

ETH Zurich: Zurich, CH

2002-01-01 to 2005-06-30 | Postdoctoral assistant (Insitute of Cell Biology)
Employment
Source: Self-asserted source
Massimo Lopes

IFOM-IEO Campus: Milano, Lombardia, IT

2000-12-01 to 2001-12-31 | Postdoctoral assistant (Foiani lab)
Employment
Source: Self-asserted source
Massimo Lopes

University of Milan: Milan, IT

1997-11-01 to 2000-11-29 | PhD student (Genetics and Microbiology)
Employment
Source: Self-asserted source
Massimo Lopes

Education and qualifications (2)

University of Milan: Milan, IT

1997-11-01 to 2000-11-29 | PhD Genetics (Genetics and Microbiology)
Education
Source: Self-asserted source
Massimo Lopes

University of Milan: Milan, IT

1996-02-01 to 1997-07-31 | M. Sc. Biology (Genetics and Microbiology)
Education
Source: Self-asserted source
Massimo Lopes

Professional activities (14)

University of Zurich: Zurich, CH

2014-03 to present | Coordinator of the Master Program in Cancer Biology at the University of Zurich (Institute of Molecular Cancer Research)
Service
Source: Self-asserted source
Massimo Lopes

University of Zurich: Zurich, CH

2008-08 to present | Coordinator of two courses for Master Students at the University of Zurich: BIO246, Genomic Instability and Molecular Cancer Research; BIO257, DNA metabolism and Cancer (Institute of Molecular Cancer Research)
Service
Source: Self-asserted source
Massimo Lopes

University of Zurich: Zurich, CH

2007-05 to present | Responsible Faculty Member for >50 internal and external PhD theses at the Science Faculty of the University of Zurich (Institute of Molecular Cancer Research)
Service
Source: Self-asserted source
Massimo Lopes

Wilhelm Bernhard Workshop : Nievzny Novogorod, RU

2017 to 2017 | Young Investigator Award
Distinction
Source: Self-asserted source
Massimo Lopes

European Research Council: Brussels, BE

2014 to 2019 | ERC Consolidator Grant
Distinction
Source: Self-asserted source
Massimo Lopes

University of Zurich: Zurich, CH

2013 to 2013 | Götz Preis for “Excellence in Research at the Faculty of Medicine in Zurich” (Faculty of Medicine)
Distinction
Source: Self-asserted source
Massimo Lopes

European Molecular Biology Organization: Heidelberg, DE

2012 | Young Investigator Award
Distinction
Source: Self-asserted source
Massimo Lopes

Swiss National Science Foundation: Bern, CH

2007 to 2013 | SNF Professorship
Distinction
Source: Self-asserted source
Massimo Lopes

Ernst Theodor Jucker Foundation: Thalwil, CH

2006 to 2006 | Award for "High quality research in cancer-related fields"
Distinction
Source: Self-asserted source
Massimo Lopes

Charles Rodolphe Brupbacher Foundation: Zurich, CH

2003 to 2003 | Young Investigator Award (cancer research)
Distinction
Source: Self-asserted source
Massimo Lopes

Human Frontier Science Program: Strasbourg, FR

2002 to 2005 | Long Term Postdoctoral Fellowship
Distinction
Source: Self-asserted source
Massimo Lopes

SIBBM (Societa’ Italiana di Biofisica e Biologia Molecolare) : Rome, IT

2002 to 2002 | Best paper award (2001)
Distinction
Source: Self-asserted source
Massimo Lopes

Fondazione Carlo Erba: Rome, IT

2002 to 2002 | Cecilia Cioffrese Award (Cancer Research)
Distinction
Source: Self-asserted source
Massimo Lopes

Associazione Genetica Italiana (AGI): Rome, IT

2001 to 2001 | Best PhD thesis in Genetics in Italy in year 2000
Distinction
Source: Self-asserted source
Massimo Lopes

Funding (15)

Deciphering the replication stress response at high resolution, in the context of nuclear architecture

2023-10 to 2027-09 | Grant
Swiss National Science Foundation (Bern, CH)
GRANT_NUMBER:

310030_219393

Source: Self-asserted source
Massimo Lopes

Accelerated DNA replication as molecular determinant and therapeutic opportunity in haematological malignancies

2023-01 to 2026-12 | Grant
Swiss National Science Foundation (Bern, CH)
Source: Self-asserted source
Massimo Lopes

Non-canonical mechanisms of breast tumorigenesis in BRCA2 mutation carriers

2023-01 to 2026-12 | Grant
Krebsliga Schweiz (Bern, CH)
Source: Self-asserted source
Massimo Lopes

Non-canonical mechanisms of breast tumorigenesis in BRCA2 mutation carriers

2021-09 to 2022-08 | Grant
Krebsliga Zurich (Zurich, CH)
Source: Self-asserted source
Massimo Lopes

Identifying novel replication fork remodelling factors as targets for cancer chemosensitization

2020-01 to 2020-12 | Grant
Novartis Foundation (Basel, CH)
Source: Self-asserted source
Massimo Lopes

Deciphering Tumorigenesis driven by Replication-associated DNA Damage

2019-04 to 2021-08 | Grant
Cancer Research Center (Zurich, CH)
Source: Self-asserted source
Massimo Lopes

Mechanisms of fork protection by the onco-suppressor BRCA2, as molecular determinants of cancer chemotherapy

2017-03 to 2020-02 | Grant
Oncosuisse (Bern, CH)
Source: Self-asserted source
Massimo Lopes

Replication Fork Remodelling Upon Cancer-relevant Genotoxic Stress

2016-10 to 2019-09 | Grant
Swiss National Science Foundation (Bern, CH)
Source: Self-asserted source
Massimo Lopes

Replication Stress and Cancer (ReStreCa)

2014-10 to 2019-09 | Grant
European Research Council (Brussels, BE)
Source: Self-asserted source
Massimo Lopes

Mechanistic Insights into Replication Stress, implicated in cancer and neurodegenerative syndromes

2013-10 to 2016-09 | Grant
Swiss National Science Foundation (Bern, CH)
Source: Self-asserted source
Massimo Lopes

Mechanistic Insight into Oncogene-Induced Replication Stress

2013-03 to 2016-02 | Grant
Oncosuisse (Bern, CH)
Source: Self-asserted source
Massimo Lopes

Mechanistic Insight into Replication Fork Reversal under Genotoxic Stress

2012-10 to 2015-09 | Grant
Promedica Stiftung (Bern, CH)
Source: Self-asserted source
Massimo Lopes

Structural and genomic insights into oncogene-induced DNA replication stress

2012-10 to 2013-09 | Grant
Krebsliga Zurich (Zurich, CH)
Source: Self-asserted source
Massimo Lopes

Uncovering the structural determinants of DNA replication stress induced by cancer chemotherapeutics

2011-07 to 2012-06 | Grant
Fonds zur Förderung des akademischen Nachwuchses (FAN) (Zurich, CH)
Source: Self-asserted source
Massimo Lopes

Towards the structural visualization of genome instability during DNA replication

Grant
Swiss National Science Foundation (Bern, CH)
Source: Self-asserted source
Massimo Lopes

Peer review (5 reviews for 4 publications/grants)

Review activity for DNA repair. (1)
Review activity for Molecular cell. (2)
Review activity for Nature (1)
Review activity for Nature communications (1)