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Works (17)

Resistance of estrogen receptor function to BET bromodomain inhibition is mediated by transcriptional coactivator cooperativity

Nature Structural & Molecular Biology
2025-01 | Journal article
DOI: 10.1038/s41594-024-01384-6
Contributors: Sicong Zhang; Robert G. Roeder
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The BAF complex enhances transcription through interaction with H3K56ac in the histone globular domain

Nature Communications
2024-11-07 | Journal article
DOI: 10.1038/s41467-024-53981-0
Contributors: Kwangbeom Hyun; Jihye Ahn; Hyoungmin Kim; Jihyun Kim; Yong-In Kim; Hee-Sung Park; Robert G. Roeder; J. Eugene Lee; Jaehoon Kim
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Regulation of the RNA polymerase II pre-initiation complex by its associated coactivators

Nature Reviews Genetics
2023-11 | Journal article
DOI: 10.1038/s41576-023-00630-9
Contributors: Sohail Malik; Robert G. Roeder
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Michael R. Green (1954–2023)

Molecular Cell
2023-07 | Journal article
DOI: 10.1016/j.molcel.2023.06.027
Contributors: Robert G. Roeder; Sara K. Deibler; Allan Jacobson; James W. Lillie; Michael Rosbash; Robert H. Singer; Narendra Wajapeyee
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Michael R. Green (1954–2023)

Cell
2023-06 | Journal article
DOI: 10.1016/j.cell.2023.05.034
Contributors: Robert G. Roeder; Sara K. Deibler; Allan Jacobson; James W. Lillie; Michael Rosbash; Robert H. Singer; Narendra Wajapeyee
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Two target gene activation pathways for orphan ERR nuclear receptors

Cell Research
2023-01-16 | Journal article
DOI: 10.1038/s41422-022-00774-z
Contributors: Tomoyoshi Nakadai; Miho Shimada; Keiichi Ito; Murat Alper Cevher; Chi-Shuen Chu; Kohei Kumegawa; Reo Maruyama; Sohail Malik; Robert G Roeder
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LYL1 facilitates AETFC assembly and gene activation by recruiting CARM1 in t(8;21) AML

Proceedings of the National Academy of Sciences
2022-10-18 | Journal article
DOI: 10.1073/pnas.2213718119
Contributors: Qian Chen; Murat A. Cevher; Qi Jiang; Saisai Wang; Xiaojian Sun; Robert G. Roeder; Mo Chen
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A PRC2-Kdm5b axis sustains tumorigenicity of acute myeloid leukemia

Proceedings of the National Academy of Sciences
2022-03 | Journal article
DOI: 10.1073/pnas.2122940119
Contributors: Zhihong Ren; Arum Kim; Yu-Ting Huang; Wen-Chieh Pi; Weida Gong; Xufen Yu; Jun Qi; Jian Jin; Ling Cai; Robert G. Roeder et al.
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DOT1L complex regulates transcriptional initiation in human erythroleukemic cells

Proceedings of the National Academy of Sciences
2021-07-06 | Journal article
DOI: 10.1073/pnas.2106148118
Contributors: Aiwei Wu; Junhong Zhi; Tian Tian; Ali Cihan; Murat A. Cevher; Ziling Liu; Yael David; Tom W. Muir; Robert G. Roeder; Ming Yu
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The regulatory enzymes and protein substrates for the lysine β-hydroxybutyrylation pathway

Science Advances
2021-02-26 | Journal article
DOI: 10.1126/sciadv.abe2771
Contributors: He Huang; Di Zhang; Yejing Weng; Kyle Delaney; Zhanyun Tang; Cong Yan; Shankang Qi; Chao Peng; Philip A. Cole; Robert G. Roeder et al.
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Histone H3Q5 serotonylation stabilizes H3K4 methylation and potentiates its readout

Proceedings of the National Academy of Sciences
2021-02-09 | Journal article
DOI: 10.1073/pnas.2016742118
Contributors: Shuai Zhao; Kelly N. Chuh; Baichao Zhang; Barbara E. Dul; Robert E. Thompson; Lorna A. Farrelly; Xiaohui Liu; Ning Xu; Yi Xue; Robert G. Roeder et al.
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Mediator subunit MED1 is required for E2A-PBX1–mediated oncogenic transcription and leukemic cell growth

Proceedings of the National Academy of Sciences
2021-02-09 | Journal article
DOI: 10.1073/pnas.1922864118
Contributors: Yu-Ling Lee; Keiichi Ito; Wen-Chieh Pi; I-Hsuan Lin; Chi-Shuen Chu; Sohail Malik; I-Hsin Cheng; Wei-Yi Chen; Robert G. Roeder
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Regulation of hepatocyte cell cycle re-entry by RNA polymerase II-associated Gdown1

Cell Cycle
2020-12-01 | Journal article
DOI: 10.1080/15384101.2020.1843776
Contributors: Miki Jishage; Robert G. Roeder
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E2A-PBX1 functions as a coactivator for RUNX1 in acute lymphoblastic leukemia

Blood
2020-07-02 | Journal article
DOI: 10.1182/blood.2019003312
Contributors: Wen-Chieh Pi; Jun Wang; Miho Shimada; Jia-Wei Lin; Huimin Geng; Yu-Ling Lee; Rui Lu; Dongxu Li; Gang Greg Wang; Robert G. Roeder et al.
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50+ years of eukaryotic transcription: an expanding universe of factors and mechanisms

Nature Structural & Molecular Biology
2019-09 | Journal article
DOI: 10.1038/s41594-019-0287-x
Contributors: Robert G. Roeder
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PML–RARα induces all-trans retinoic acid-dependent transcriptional activation through interaction with MED1

Transcription
2019-05-27 | Journal article
DOI: 10.1080/21541264.2019.1624467
Contributors: Tomoya Fukuoka; Asami Kawai; Taku Takahara; Mahiro Mori; Robert G. Roeder; Natsumi Hasegawa; Mitsuhiro Ito
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Architecture of Pol II(G) and molecular mechanism of transcription regulation by Gdown1

Nature Structural & Molecular Biology
2018-09 | Journal article
DOI: 10.1038/s41594-018-0118-5
Contributors: Miki Jishage; Xiaodi Yu; Yi Shi; Sai J. Ganesan; Wei-Yi Chen; Andrej Sali; Brian T. Chait; Francisco J. Asturias; Robert G. Roeder
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Peer review (1 review for 1 publication/grant)

Review activity for Cell discovery. (1)
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