Personal information

Other IDs

Scopus Author ID: 7003315592
ResearcherID: F-4683-2011

Keywords

EGFR, Insulin Receptor, Growth Factor Receptor, RTK, Membrane, Lipid-protein Interaction

Countries

Germany

Activities

Collapse all

Employment (5)

University Hospital Dresden and Faculty of Medicine Carl Gustav Carus , TU Dresden: Dresden, DE

2021-07-01 to present | Full Professor (Center of Membrane Biochemistry and Lipid Research)
Employment
Source: Self-asserted source
Ünal Coskun

Paul Langerhans Institute Dresden of the Helmholtz Zentrum Munich at the University Clinic Carl Gustav Carus, TU Dresden: Dresden, DE

2020-08-01 to 2021-06-30 | Assoc. Prof. (Membrane Biochemistry and Lipid Research)
Employment
Source: Self-asserted source
Ünal Coskun

Paul Langerhans Institute Dresden of the Helmholtz Zentrum Munich at the University Clinic Carl Gustav Carus, TU Dresden: Dresden, DE

2012-09 to 2020-07-31 | Research group Leader
Employment
Source: Self-asserted source
Ünal Coskun

Max Planck Institute of Cell Biology and Genetics: Dresden, DE

2005-05 to 2012-08 | Postdoctoral Fellow
Employment
Source: Self-asserted source
Ünal Coskun

Universität des Saarlandes: Homburg/Saar, DE

2005-02 | PhD student (Department of Biophysics)
Employment
Source: Self-asserted source
Ünal Coskun

Works (50 of 60)

Items per page:
Page 1 of 2

Purification of time-resolved insulin granules reveals proteomic and lipidomic changes during granule aging

Cell reports
2024-03-26 | Journal article | Author
DOI: 10.1016/j.celrep.2024.113836
SOURCE-WORK-ID:

84797dc4-89f4-49b2-b038-e0c34216bb44

PMID: 38421874
EID:

2-s2.0-85186764040
Contributors: Martin Neukam; Pia Sala; Andreas-David Brunner; Katharina Ganß; Alessandra Palladini; Michal Grzybek; Oleksandra Topcheva; Jovana Vasiljević; Johannes Broichhagen; Kai Johnsson et al.
Source: check_circle
FIS TU Dresden

IGFR-L1 antibodies and uses thereof

2023-01-26 | Patent
SOURCE-WORK-ID:

9db91648-8708-46c3-b275-cef45ba03589
Contributors: Ünal Coskun; Michal Grzybek; Heiko Lickert
Source: check_circle
FIS TU Dresden

Synaptotagmin-13 orchestrates pancreatic endocrine cell egression and islet morphogenesis.

Nature communications
2022-08-04 | Journal article
DOI: 10.1038/s41467-022-31862-8
PMID: 35927244
PMC: PMC9352765
Contributors: Ünal Coskun
Source: Self-asserted source
Ünal Coskun
grade
Preferred source (of 2)‎

A gene expression map of host immune response in human brucellosis.

Frontiers in immunology
2022-08-01 | Journal article
DOI: 10.3389/fimmu.2022.951232
PMID: 35979363
Contributors: Ünal Coskun
Source: Self-asserted source
Ünal Coskun
grade
Preferred source (of 2)‎

Symmetric and asymmetric receptor conformation continuum induced by a new insulin.

Nature chemical biology
2022-03 | Journal article
DOI: 10.1038/s41589-022-00981-0
PMID: 35289328
Contributors: Xiong X; Blakely A; Kim JH; Menting JG; Schäfer IB; Schubert HL; Agrawal R; Gutmann T; Delaine C; Zhang YW et al.
Source: Self-asserted source
Ünal Coskun via Europe PubMed Central

The RNA binding protein human antigen R is a gatekeeper of liver homeostasis.

Hepatology (Baltimore, Md.)
2021-09-14 | Journal article
DOI: 10.1002/hep.32153
PMID: 34519101
Source: Self-asserted source
Ünal Coskun
grade
Preferred source (of 2)‎

Nonalcoholic fatty liver disease stratification by liver lipidomics.

Journal of lipid research
2021-08-10 | Journal article
DOI: 10.1016/j.jlr.2021.100104
PMID: 34384788
PMC: PMC8488246
Source: Self-asserted source
Ünal Coskun
grade
Preferred source (of 2)‎

HIF2α is a direct regulator of neutrophil motility.

Blood
2021-06-01 | Journal article
DOI: 10.1182/blood.2020007505
PMID: 33619535
Source: Self-asserted source
Ünal Coskun

Inceptor counteracts insulin signalling in β-cells to control glycaemia.

Nature
2021-01-27 | Journal article
DOI: 10.1038/s41586-021-03225-8
PMID: 33505018
Source: Self-asserted source
Ünal Coskun
grade
Preferred source (of 2)‎

Insulin und sein Rezeptor – Spezifität durch Kombinatorik?

Biospektrum
2020-06-01 | Journal article | Author
DOI: 10.1007/s12268-020-1395-1
SOURCE-WORK-ID:

b8f3d6b5-93da-4b89-8e97-b224300f2f9a

EID:

2-s2.0-85086831983
Contributors: Theresia Gutmann; Ünal Coskun
Source: check_circle
FIS TU Dresden

Live-cell lipid biochemistry reveals a role of diacylglycerol side-chain composition for cellular lipid dynamics and protein affinities.

Proceedings of the National Academy of Sciences of the United States of America
2020-03-25 | Journal article
DOI: 10.1073/pnas.1912684117
PMID: 32213584
PMC: PMC7149225
Source: Self-asserted source
Ünal Coskun
grade
Preferred source (of 2)‎

Cryo-EM structure of the complete and ligand-saturated insulin receptor ectodomain.

The Journal of cell biology
2020-01-01 | Journal article
DOI: 10.1083/jcb.201907210
PMID: 31727777
PMC: PMC7039211
Source: Self-asserted source
Ünal Coskun
grade
Preferred source (of 2)‎

Cryo-EM structure of the complete and ligand-saturated insulin receptor ectodomain

bioRxiv
2019-06-21 | Preprint
DOI: 10.1101/679233
Source: Self-asserted source
Ünal Coskun

Multi-omics insights into functional alterations of the liver in insulin-deficient diabetes mellitus.

Molecular metabolism
2019-06-04 | Journal article
DOI: 10.1016/j.molmet.2019.05.011
PMID: 31221621
PMC: PMC6667734
Source: Self-asserted source
Ünal Coskun
grade
Preferred source (of 2)‎

Comprehensive and quantitative analysis of white and brown adipose tissue by shotgun lipidomics

Molecular Metabolism
2019-01 | Journal article
DOI: 10.1016/j.molmet.2019.01.009
Part of ISSN: 2212-8778
Contributors: Michal Grzybek; Alessandra Palladini; Vasileia I. Alexaki; Michal A. Surma; Kai Simons; Triantafyllos Chavakis; Christian Klose; Ünal Coskun
Source: Self-asserted source
Ünal Coskun via Crossref Metadata Search

Comprehensive and quantitative analysis of white and brown adipose tissue by shotgun lipidomics

2018-11 | Other
DOI: 10.1101/470690
OTHER-ID:

PPR61997
Contributors: Grzybek M; Palladini A; Alexaki VI; Surma MA; Simons K; Chavakis T; Klose C; Coskun U
Source: Self-asserted source
Ünal Coskun via Europe PubMed Central

DEL-1 promotes macrophage efferocytosis and clearance of inflammation

Nature Immunology
2018-11 | Journal article
DOI: 10.1038/s41590-018-0249-1
Part of ISSN: 1529-2908
Contributors: Ioannis Kourtzelis; Xiaofei Li; Ioannis Mitroulis; Daniel Grosser; Tetsuhiro Kajikawa; Baomei Wang; Michal Grzybek; Janusz von Renesse; Aleksander Czogalla; Maria Troullinaki et al.
Source: Self-asserted source
Ünal Coskun via Crossref Metadata Search

Novel IGFR-like 2 receptor and uses thereof

2018-11-21 | Patent
SOURCE-WORK-ID:

35682872-0c3e-421e-b22d-6bb086132359
Contributors: Ünal Coskun; Sarah Homberg; Heiko Lickert
Source: check_circle
FIS TU Dresden

A Temperature-Dependent Switch in Feeding Preference Improves Drosophila Development and Survival in the Cold.

Developmental cell
2018-09 | Journal article
DOI: 10.1016/j.devcel.2018.05.028
PMID: 30253170
Contributors: Brankatschk M; Gutmann T; Knittelfelder O; Palladini A; Prince E; Grzybek M; Brankatschk B; Shevchenko A; Coskun Ü; Eaton S
Source: Self-asserted source
Ünal Coskun via Europe PubMed Central

Visualization of ligand-induced transmembrane signaling in the full-length human insulin receptor.

The Journal of cell biology
2018-02 | Journal article
DOI: 10.1083/jcb.201711047
PMID: 29453311
Contributors: Gutmann T; Kim KH; Grzybek M; Walz T; Coskun Ü
Source: Self-asserted source
Ünal Coskun via Europe PubMed Central

Detection of human disease conditions by single-cell morpho-rheological phenotyping of blood.

eLife
2018-01 | Journal article
DOI: 10.7554/elife.29213
PMID: 29331015
Contributors: Toepfner N; Herold C; Otto O; Rosendahl P; Jacobi A; Kräter M; Stächele J; Menschner L; Herbig M; Ciuffreda L et al.
Source: Self-asserted source
Ünal Coskun via Europe PubMed Central
grade
Preferred source (of 2)‎

Modulation of Myelopoiesis Progenitors Is an Integral Component of Trained Immunity.

Cell
2018-01 | Journal article
DOI: 10.1016/j.cell.2017.11.034
PMID: 29328910
PMC: PMC5766828
Contributors: Mitroulis I; Ruppova K; Wang B; Chen LS; Grzybek M; Grinenko T; Eugster A; Troullinaki M; Palladini A; Kourtzelis I et al.
Source: Self-asserted source
Ünal Coskun via Europe PubMed Central
grade
Preferred source (of 2)‎

Calcium Directly Regulates Phosphatidylinositol 4,5-Bisphosphate Headgroup Conformation and Recognition

Journal of the American Chemical Society
2017 | Journal article
DOI: 10.1021/jacs.6b11760
WOSUID:

WOS:000397477700019
Contributors: Bilkova, Eva; Pleskot, Roman; Rissanen, Sami; Sun, Simou; Czogalla, Aleksander; Cwiklik, Lukasz; Rog, Tomasz; Vattulainen, Ilpo; Cremer, Paul S.; Jungwirth, Pavel et al.
Source: Self-asserted source
Ünal Coskun via ResearcherID
grade
Preferred source (of 2)‎

Spatiotemporal Control of Lipid Conversion, Actin-Based Mechanical Forces, and Curvature Sensors during Clathrin/AP-1-Coated Vesicle Biogenesis

Cell Reports
2017 | Journal article
DOI: 10.1016/j.celrep.2017.08.013
EID:

2-s2.0-85028391914
Contributors: Anitei, M.; Stange, C.; Czupalla, C.; Niehage, C.; Schuhmann, K.; Sala, P.; Czogalla, A.; Pursche, T.; Coskun, Ü.; Shevchenko, A. et al.
Source: Self-asserted source
Ünal Coskun via Scopus - Elsevier
grade
Preferred source (of 2)‎

The Munich MIDY Pig Biobank - A unique resource for studying organ crosstalk in diabetes

Molecular Metabolism
2017 | Journal article
DOI: 10.1016/j.molmet.2017.06.004
WOSUID:

WOS:000405803000014
Contributors: Blutke, Andreas; Renner, Simone; Flenkenthaler, Florian; Backman, Mattias; Haesner, Serena; Kemter, Elisabeth; Laendstroem, Erik; Braun-Reichhart, Christina; Albl, Barbara; Streckel, Elisabeth et al.
Source: Self-asserted source
Ünal Coskun via ResearcherID
grade
Preferred source (of 2)‎

Visualization of ligand-induced transmembrane signalling in the full-length human insulin receptor

bioRxiv
2017 | Journal article
DOI: 10.1101/207928
ARXIV:

https://www.biorxiv.org/content/early/2017/10/23/207928.full.pdf
Source: Self-asserted source
Ünal Coskun

Monitoring Membrane Lipidome Turnover by Metabolic 15N-Labeling and Shotgun Ultra-High Resolution Orbitrap FT MS.

Analytical chemistry
2017-11 | Journal article
DOI: 10.1021/acs.analchem.7b03437
PMID: 29111682
Source: Self-asserted source
Ünal Coskun via Europe PubMed Central
grade
Preferred source (of 2)‎

Key steps in unconventional secretion of fibroblast growth factor 2 reconstituted with purified components.

eLife
2017-07 | Journal article
DOI: 10.7554/elife.28985
PMID: 28722655
Source: Self-asserted source
Ünal Coskun via Europe PubMed Central
grade
Preferred source (of 2)‎

Membrane Lipid Galore

Journal of Molecular Biology
2016 | Journal article
DOI: 10.1016/j.jmb.2016.11.004
EID:

2-s2.0-84996486872
Contributors: Simons, K.; Coskun, Ü.
Source: Self-asserted source
Ünal Coskun via Scopus - Elsevier

Shotgun Lipidomics in der biomedizinischen und klinischen Forschung: Hochdurchsatzscreening

BioSpektrum
2016 | Journal article
DOI: 10.1007/s12268-016-0739-3
EID:

2-s2.0-84989299816
Contributors: Klose, C.; Coskun, Ü.
Source: Self-asserted source
Ünal Coskun via Scopus - Elsevier
grade
Preferred source (of 2)‎

Adaptive Lipid Packing and Bioactivity in Membrane Domains

PLoS One
2015 | Journal article
DOI: 10.1371/journal.pone.0123930
WOSUID:

WOS:000353332000049
Contributors: Sezgin, Erdinc; Gutmann, Theresia; Buhl, Tomasz; Dirkx, Ron; Grzybek, Michal; Coskun, Uenal; Solimena, Michele; Simons, Kai; Levental, Ilya; Schwille, Petra
Source: Self-asserted source
Ünal Coskun via ResearcherID
grade
Preferred source (of 3)‎

Co-option of Membrane Wounding Enables Virus Penetration into Cells

Cell Host & Microbe
2015 | Journal article
DOI: 10.1016/j.chom.2015.06.006
WOSUID:

WOS:000357687000012
Contributors: Luisoni, Stefania; Suomalainen, Maarit; Boucke, Karin; Tanner, Lukas B.; Wenk, Markus R.; Guan, Xue Li; Grzybek, Michal; Coskun, Uenal; Greber, Urs F.
Source: Self-asserted source
Ünal Coskun via ResearcherID
grade
Preferred source (of 3)‎

Functional Role of Membrane Lipids in EGF Receptor Dynamics and Regulation

Cell Membrane Nanodomains: From Biochemistry to Nanoscopy
2015 | Book
WOSUID:

BCI:BCI201500495231
Contributors: Grzybek, Michal; Gutmann, Theresia; Coskun, Uenal; Cambi, A; Lidke, DS
Source: Self-asserted source
Ünal Coskun via ResearcherID

N-Glycosylation as determinant of epidermal growth factor receptor conformation in membranes

Proceedings of the National Academy of Sciences of the United States of America
2015 | Journal article
DOI: 10.1073/pnas.1503262112
WOSUID:

WOS:000352287800049
Contributors: Kaszuba, Karol; Grzybek, Michal; Orlowski, Adam; Danne, Reinis; Rog, Tomasz; Simons, Kai; Coskun, Uenal; Vattulainen, Ilpo
Source: Self-asserted source
Ünal Coskun via ResearcherID
grade
Preferred source (of 3)‎

Structural Basis of Dynamic Membrane Recognition by trans-Golgi Network Specific FAPP Proteins

Journal of Molecular Biology
2015 | Journal article
DOI: 10.1016/j.jmb.2014.12.023
WOSUID:

WOS:000350076400021
Contributors: Lenoir, Marc; Grzybek, Michal; Majkowski, Michal; Rajesh, Sandya; Kaur, Jaswant; Whittaker, Sara B. -M.; Coskun, Uenal; Overduin, Michael
Source: Self-asserted source
Ünal Coskun via ResearcherID
grade
Preferred source (of 3)‎

Quantified CSF antibody reactivity against myelin in multiple sclerosis

Ann Clin Transl Neurol
2015-11 | Journal article
DOI: 10.1002/acn3.264
Contributors: Xingwen Sun; Mostafa Bakhti; Dirk Fitzner; Mareike Schnaars; Niels Kruse; Ünal Coskun; Christiane Kremser; Klaus Willecke; Ludwig Kappos; Jens Kuhle et al.
Source: Self-asserted source
Ünal Coskun via Crossref Metadata Search
grade
Preferred source (of 2)‎

Two-Dimensional Trap for Ultrasensitive Quantification of Transient Protein Interactions

ACS Nano
2015-10 | Journal article
DOI: 10.1021/acsnano.5b02696
Contributors: Oliver Beutel; Friedrich Roder; Oliver Birkholz; Christian Rickert; Heinz-Jürgen Steinhoff; Michał Grzybek; Ünal Coskun; Jacob Piehler
Source: Self-asserted source
Ünal Coskun via Crossref Metadata Search
grade
Preferred source (of 3)‎

Analysis of Transmembrane Domains and Lipid Modified Peptides with Matrix-Assisted Laser Desorption Ionization-Time-of-Flight Mass Spectrometry

Analytical Chemistry
2014 | Journal article
DOI: 10.1021/ac500446z
WOSUID:

WOS:000334658000009
Contributors: Gerl, Mathias J.; Sachsenheimer, Timo; Grzybek, Michal; Coskun, Uenal; Wieland, Felix T.; Bruegger, Britta
Source: Self-asserted source
Ünal Coskun via ResearcherID
grade
Preferred source (of 3)‎

Validity and applicability of membrane model systems for studying interactions of peripheral membrane proteins with lipids

Biochimica Et Biophysica Acta-Molecular and Cell Biology of Lipids
2014 | Journal article
DOI: 10.1016/j.bbalip.2013.12.012
WOSUID:

WOS:000339039700005
Contributors: Czogalla, Aleksander; Grzybek, Michal; Jones, Walis; Coskun, Uenal
Source: Self-asserted source
Ünal Coskun via ResearcherID
grade
Preferred source (of 3)‎

Functional role of membrane lipids in EGF receptor dynamics and regulation

Cell Membrane Nanodomains
2014-01-01 | Book chapter | Author
DOI: 10.1201/b17634
SOURCE-WORK-ID:

97ee9d83-1863-492c-b7d3-3871d464ad57

EID:

2-s2.0-85053656733

Part of ISBN: 978-1-4822-0991-4
Part of ISBN: 9781482209891
Contributors: Michal Grzybek; Theresia Gutmann; Ünal Coskun
Source: check_circle
FIS TU Dresden

Partitioning, diffusion, and ligand binding of raft lipid analogs in model and cellular plasma membranes

Biochimica Et Biophysica Acta-Biomembranes
2012 | Journal article
DOI: 10.1016/j.bbamem.2012.03.007
WOSUID:

WOS:000304502600023
Contributors: Sezgin, E.; Levental, I.; Grzybek, M.; Schwarzmann, G.; Mueller, V.; Honigmann, A.; Belov, V. N.; Eggeling, C.; Coskun, U.; Simons, K. et al.
Source: Self-asserted source
Ünal Coskun via ResearcherID
grade
Preferred source (of 2)‎

Cell Membranes: The Lipid Perspective

Structure
2011 | Journal article
DOI: 10.1016/j.str.2011.10.010
WOSUID:

WOS:000296999700005
Contributors: Coskun, Uenal; Simons, Kai
Source: Self-asserted source
Ünal Coskun via ResearcherID
grade
Preferred source (of 2)‎

Cholesterol modulates glycolipid conformation and receptor activity

Nature Chemical Biology
2011 | Journal article
DOI: 10.1038/nchembio.551
WOSUID:

WOS:000289617800008
Contributors: Lingwood, Daniel; Binnington, Beth; Rog, Tomasz; Vattulainen, Ilpo; Grzybek, Michal; Coskun, Uenal; Lingwood, Clifford A.; Simons, Kai
Source: Self-asserted source
Ünal Coskun via ResearcherID
grade
Preferred source (of 2)‎

Regulation of human EGF receptor by lipids

Proceedings of the National Academy of Sciences of the United States of America
2011 | Journal article
DOI: 10.1073/pnas.1105666108
WOSUID:

WOS:000291106200032
Contributors: Coskun, Uenal; Grzybek, Michal; Drechsel, David; Simons, Kai
Source: Self-asserted source
Ünal Coskun via ResearcherID
grade
Preferred source (of 2)‎

Membrane rafting: From apical sorting to phase segregation

Febs Letters
2010 | Journal article
DOI: 10.1016/j.febslet.2009.12.043
WOSUID:

WOS:000276717600009
Contributors: Coskun, Uenal; Simons, Kai
Source: Self-asserted source
Ünal Coskun via ResearcherID
grade
Preferred source (of 2)‎

Palmitoylation regulates raft affinity for the majority of integral raft proteins

Proceedings of the National Academy of Sciences of the United States of America
2010 | Journal article
DOI: 10.1073/pnas.1016184107
WOSUID:

WOS:000285521800024
Contributors: Levental, Ilya; Lingwood, Daniel; Grzybek, Michal; Coskun, Uenal; Simons, Kai
Source: Self-asserted source
Ünal Coskun via ResearcherID
grade
Preferred source (of 2)‎

Structural basis of wedging the Golgi membrane by FAPP pleckstrin homology domains

Embo Reports
2010 | Journal article
DOI: 10.1038/embor.2010.28
WOSUID:

WOS:000276117100012
Contributors: Lenoir, Marc; Coskun, Uenal; Grzybek, Michal; Cao, Xinwang; Buschhorn, Sabine B.; James, Jonathan; Simons, Kai; Overduin, Michael
Source: Self-asserted source
Ünal Coskun via ResearcherID
grade
Preferred source (of 2)‎

Golgi protein FAPP2 tubulates membranes

Proceedings of the National Academy of Sciences of the United States of America
2009 | Journal article
DOI: 10.1073/pnas.0911789106
WOSUID:

WOS:000272795300022
Contributors: Cao, Xinwang; Coskun, Uenal; Roessle, Manfred; Buschhorn, Sabine B.; Grzybek, Michal; Dafforn, Timothy R.; Lenoir, Marc; Overduin, Michael; Simons, Kai
Source: Self-asserted source
Ünal Coskun via ResearcherID

Reconstitution of Rab- and SNARE-dependent membrane fusion by synthetic endosomes

Nature
2009 | Journal article
DOI: 10.1038/nature08107
WOSUID:

WOS:000267636700035
Contributors: Ohya, Takeshi; Miaczynska, Marta; Coskun, Uenal; Lommer, Barbara; Runge, Anja; Drechsel, David; Kalaidzidis, Yannis; Zerial, Marino
Source: Self-asserted source
Ünal Coskun via ResearcherID
grade
Preferred source (of 2)‎

Bioenergetics of archaea: ATP synthesis under harsh environmental conditions

Journal of Molecular Microbiology and Biotechnology
2005 | Journal article
DOI: 10.1159/000091563
WOSUID:

WOS:000237196300009
Contributors: Muller, V; Lemker, T; Lingl, A; Weidner, C; Coskun, U; Gruber, G
Source: Self-asserted source
Ünal Coskun via ResearcherID
grade
Preferred source (of 2)‎
Items per page:
Page 1 of 2
How many people are using ORCID?