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Hodges lab

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Employment (1)

Baylor College of Medicine: Houston, TX, US

2017-07-31 to present | Assistant Professor (Department of Molecular & Cellular Biology)
Employment
Source: Self-asserted source
H. Courtney Hodges

Education and qualifications (2)

Stanford University School of Medicine: Stanford, CA, US

2010-01-04 to 2017-07-31 | Postdoctoral fellow (Department of Pathology)
Education
Source: Self-asserted source
H. Courtney Hodges

University of California Berkeley: Berkeley, CA, US

2003-08-01 to 2009-12-19 | Ph.D. (Biophysics)
Education
Source: Self-asserted source
H. Courtney Hodges

Funding (4)

Dynamic effects of cancer mutations on the mammalian SWI/SNF ATPase Brg

Source: Self-asserted source
H. Courtney Hodges via DimensionsWizard

Dynamic effects of cancer mutations on the mammalian SWI/SNF ATPase Brg

Source: Self-asserted source
H. Courtney Hodges via DimensionsWizard

Structural and Dynamic Changes of Chromatin Remodeling at a Developmental Switch

2012-04-01 to 2014-07-31 | Grant
National Institute of Child Health and Human Development (n/a, US)
URL: https://grants.uberresearch.com/100000071/F32HD072627/Structural-and-Dynamic-Changes-of-Chromatin-Remodeling-at-a-Developmental-Switch
GRANT_NUMBER: grant.F32HD072627
Source: Self-asserted source
H. Courtney Hodges via DimensionsWizard

Revealing novel SMARCA4-related dependencies in mixed-lineage leukemia

Grant
Gabrielle’s Angel Foundation for Cancer Research (NY, NY, US)
Source: Self-asserted source
H. Courtney Hodges

Works (22)

Pharmacologic Blockade of a Pioneer Transcription Factor

Cancer Research
2024-12-16 | Journal article
DOI: 10.1158/0008-5472.CAN-24-3957
Contributors: Katerina Cermakova; H. Courtney Hodges
Source: check_circle
Crossref

Interaction modules that impart specificity to disordered protein

Trends in Biochemical Sciences
2023-05 | Journal article
DOI: 10.1016/j.tibs.2023.01.004
Contributors: Katerina Cermakova; H. Courtney Hodges
Source: check_circle
Crossref

The TFIIS N-terminal domain (TND): a transcription assembly module at the interface of order and disorder

Biochemical Society Transactions
2023-02-27 | Journal article
DOI: 10.1042/BST20220342
Contributors: Katerina Cermakova; Vaclav Veverka; H. Courtney Hodges
Source: check_circle
Crossref

Therapeutic Synergy in Esophageal Cancer and Mesothelioma Is Predicted by Dynamic BH3 Profiling

Molecular Cancer Therapeutics
2021-08-01 | Journal article
DOI: 10.1158/1535-7163.MCT-20-0887
Contributors: Deborah R. Surman; Yuan Xu; Min-Jung Lee; Jane Trepel; Kate Brown; Maheshwari Ramineni; Taylor G. Splawn; Laurence P. Diggs; H. Courtney Hodges; Jeremy L. Davis et al.
Source: check_circle
Crossref

Activation of PKA via asymmetric allosteric coupling of structurally conserved cyclic nucleotide binding domains

Nature Communications
2019-09-04 | Journal article
DOI: 10.1038/s41467-019-11930-2
Contributors: Yuxin Hao; Jeneffer P. England; Luca Bellucci; Emanuele Paci; H. Courtney Hodges; Susan S. Taylor; Rodrigo A. Maillard
Source: check_circle
Crossref

The Spatial and Genomic Hierarchy of Tumor Ecosystems Revealed by Single-Cell Technologies

Trends in Cancer
2019-07 | Journal article
DOI: 10.1016/j.trecan.2019.05.009
Contributors: Eric A. Smith; H. Courtney Hodges
Source: check_circle
Crossref

Dynamics of transcription-dependent H3K36me3 marking by the SETD2:IWS1:SPT6 ternary complex

2019-05-14 | Other
DOI: 10.1101/636084
Contributors: Katerina Cermakova; Eric A. Smith; Vaclav Veverka; H. Courtney Hodges
Source: check_circle
Crossref

Next-Generation Drugs and Probes for Chromatin Biology: From Targeted Protein Degradation to Phase Separation

Molecules
2018-08 | Journal article
DOI: 10.3390/molecules23081958
Source: check_circle
Multidisciplinary Digital Publishing Institute
grade
Preferred source (of 2)‎

Switching of the folding-energy landscape governs the allosteric activation of protein kinase A

Proceedings of the National Academy of Sciences
2018-08-07 | Journal article
DOI: 10.1073/pnas.1802510115
Contributors: Jeneffer P. England; Yuxin Hao; Lihui Bai; Virginia Glick; H. Courtney Hodges; Susan S. Taylor; Rodrigo A. Maillard
Source: check_circle
Crossref

Affinity switching of the LEDGF/p75 IBD interactome is governed by kinase-dependent phosphorylation.

Proceedings of the National Academy of Sciences of the United States of America
2018-07 | Journal article
DOI: 10.1073/pnas.1803909115
PMID: 29997176
Contributors: Sharma S; Čermáková K; De Rijck J; Demeulemeester J; Fábry M; El Ashkar S; Van Belle S; Lepšík M; Tesina P; Duchoslav V et al.
Source: Self-asserted source
H. Courtney Hodges via Europe PubMed Central

Dominant-negative SMARCA4 mutants alter the accessibility landscape of tissue-unrestricted enhancers

Nature Structural & Molecular Biology
2018-01-11 | Journal article
DOI: 10.1038/s41594-017-0007-3
Contributors: H. Courtney Hodges; Benjamin Z. Stanton; Katerina Cermakova; Chiung-Ying Chang; Erik L. Miller; Jacob G. Kirkland; Wai Lim Ku; Vaclav Veverka; Keji Zhao; Gerald R. Crabtree
Source: check_circle
Crossref

TOP2 synergizes with BAF chromatin remodeling for both resolution and formation of facultative heterochromatin

Nature Structural & Molecular Biology
2017-04-27 | Journal article
DOI: 10.1038/nsmb.3384
Contributors: Erik L Miller; Diana C Hargreaves; Cigall Kadoch; Chiung-Ying Chang; Joseph P Calarco; Courtney Hodges; Jason D Buenrostro; Kairong Cui; William J Greenleaf; Keji Zhao et al.
Source: check_circle
Crossref

A General Non-Radioactive ATPase Assay for Chromatin Remodeling Complexes.

2017-03 | Journal article
DOI: 10.1002/cpch.16
PMID: 28253434
Contributors: Stanton BZ; Hodges C; Crabtree GR; Zhao K
Source: Self-asserted source
H. Courtney Hodges via Europe PubMed Central

Smarca4 ATPase mutations disrupt direct eviction of PRC1 from chromatin

Nature Genetics
2017-02 | Journal article
DOI: 10.1038/ng.3735
Contributors: Benjamin Z Stanton; Courtney Hodges; Joseph P Calarco; Simon M G Braun; Wai Lim Ku; Cigall Kadoch; Keji Zhao; Gerald R Crabtree
Source: check_circle
Crossref

The Many Roles of BAF (mSWI/SNF) and PBAF Complexes in Cancer.

2016-08 | Journal article
DOI: 10.1101/cshperspect.a026930
PMID: 27413115
Contributors: Hodges C; Kirkland JG; Crabtree GR
Source: Self-asserted source
H. Courtney Hodges via Europe PubMed Central

Proteomic and bioinformatic analysis of mammalian SWI/SNF complexes identifies extensive roles in human malignancy.

2013-06 | Journal article
DOI: 10.1038/ng.2628
PMID: 23644491
PMC: PMC3667980
Contributors: Kadoch C; Hargreaves DC; Hodges C; Elias L; Ho L; Ranish J; Crabtree GR
Source: Self-asserted source
H. Courtney Hodges via Europe PubMed Central

Dynamics of inherently bounded histone modification domains.

2012-08 | Journal article
DOI: 10.1073/pnas.1211172109
PMID: 22847427
PMC: PMC3421184
Contributors: Hodges C; Crabtree GR
Source: Self-asserted source
H. Courtney Hodges via Europe PubMed Central

Dynamics and memory of heterochromatin in living cells.

2012-06 | Journal article
DOI: 10.1016/j.cell.2012.03.052
PMID: 22704655
PMC: PMC3422694
Contributors: Hathaway NA; Bell O; Hodges C; Miller EL; Neel DS; Crabtree GR
Source: Self-asserted source
H. Courtney Hodges via Europe PubMed Central

The elongation rate of RNA polymerase determines the fate of transcribed nucleosomes.

2011-11 | Journal article
DOI: 10.1038/nsmb.2164
PMID: 22081017
PMC: PMC3279329
Contributors: Bintu L; Kopaczynska M; Hodges C; Lubkowska L; Kashlev M; Bustamante C
Source: Self-asserted source
H. Courtney Hodges via Europe PubMed Central

ClpX(P) generates mechanical force to unfold and translocate its protein substrates.

2011-04 | Journal article
DOI: 10.1016/j.cell.2011.04.010
PMID: 21529717
PMC: PMC3686100
Contributors: Maillard RA; Chistol G; Sen M; Righini M; Tan J; Kaiser CM; Hodges C; Martin A; Bustamante C
Source: Self-asserted source
H. Courtney Hodges via Europe PubMed Central

Nucleosomal fluctuations govern the transcription dynamics of RNA polymerase II.

2009-07 | Journal article
DOI: 10.1126/science.1172926
PMID: 19644123
PMC: PMC2775800
Contributors: Hodges C; Bintu L; Lubkowska L; Kashlev M; Bustamante C
Source: Self-asserted source
H. Courtney Hodges via Europe PubMed Central

Following translation by single ribosomes one codon at a time.

2008-04 | Journal article
DOI: 10.1038/nature06716
PMID: 18327250
PMC: PMC2556548
Contributors: Wen JD; Lancaster L; Hodges C; Zeri AC; Yoshimura SH; Noller HF; Bustamante C; Tinoco I
Source: Self-asserted source
H. Courtney Hodges via Europe PubMed Central

Peer review (1 review for 1 publication/grant)

Review activity for Molecules. (1)
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