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Other IDs

ResearcherID: S-7884-2017
Scopus Author ID: 56016528500

Keywords

Pyrazine, Mycobacterium, MIC, Antituberculotics, Microbiology, Antimicrobials, Antimycotics, Tuberculosis

Countries

Czech Republic

Activities

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Employment (1)

Charles University, Faculty of Pharmacy in Hradec Kralove: Hradec Kralove, CZ

2016-08-22 to present (Department of Biological and Medical Sciences)
Employment
Source: Self-asserted source
Ondřej Janďourek

Education and qualifications (1)

Charles University, Faculty of Pharmacy in Hradec Kralove: Hradec Kralove, CZ

2011-10-01 to 2016-11-24 | Ph.D. (Department of Pharmaceutical Chemistry and Pharmaceutical Analysis)
Education
Source: Self-asserted source
Ondřej Janďourek

Works (41)

Enhancing the antimycobacterial efficacy of pyridine-4-carbohydrazide: linkage to additional antimicrobial agents via oxocarboxylic acids

RSC Medicinal Chemistry
2025 | Journal article
DOI: 10.1039/D4MD00663A
Contributors: Václav Pflégr; Klára Konečná; Jiřina Stolaříková; Jan Ősterreicher; Ondřej Janďourek; Martin Krátký
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Antimicrobial and Antiproliferative Properties of 2‐Phenyl‐N‐(Pyridin‐2‐yl)acetamides

Chemical Biology & Drug Design
2025-01 | Journal article
DOI: 10.1111/cbdd.70030
Contributors: Daria Nawrot; Barbora Koutníková; Ondřej Janďourek; Klára Konečná; Martin Novák; Pavla Paterová; Pavel Bárta; Ghada Bouz; Jan Zitko; Martin Doležal
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The appropriate nutrient conditions for methicillin-resistant Staphylococcus aureus and Candida albicans dual-species biofilm formation in vitro

Scientific Reports
2025-01-02 | Journal article
DOI: 10.1038/s41598-024-83745-1
Part of ISSN: 2045-2322
Contributors: Pavlína Vávrová; Ondřej Janďourek; Adéla Diepoltová; Petr Nachtigal; Klára Konečná
Source: Self-asserted source
Ondřej Janďourek

Stereoselective N‐Heterocyclic‐Carbene‐Catalyzed Spiroannulation as an Access Towards Spirobenzofuranone‐Fused Cyclohexenones

Advanced Synthesis & Catalysis
2024-12-17 | Journal article
DOI: 10.1002/adsc.202401111
Contributors: Ladislav Lóška; Vojtěch Dočekal; Daniel Čermák; Simona Petrželová; Milan Pour; Ivana Císařová; Klára Konečná; Ondřej Janďourek; Jan Veselý
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A hit expansion of 3‐benzamidopyrazine‐2‐carboxamide: Toward inhibitors of prolyl‐tRNA synthetase with antimycobacterial activity

Archiv der Pharmazie
2024-08 | Journal article
DOI: 10.1002/ardp.202400171
Contributors: Vinod Sukanth Kumar Pallabothula; Nechirwan Taimur Abdalrahman; Matteo Mori; Amir Hossein Fekri; Ondřej Janďourek; Klára Konečná; Pavla Paterová; Martin Novák; Paulína Dudášová‐Hatoková; Petra Štěrbová‐Kovaříková et al.
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Stereoselective N-heterocyclic-carbene-catalyzed spiroannulation as an access towards spirobenzofuranone-fused cyclohexenones

2024-05-08 | Preprint
DOI: 10.26434/chemrxiv-2024-sfxq8
Contributors: Ladislav Lóška; Vojtěch Dočekal; Daniel Čermák; Simona Petrželová; Milan Pour; Ivana Císařová; Klára Konečná; Ondřej Janďourek; Jan Veselý
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N -Pyrazinylhydroxybenzamides As Biologically Active Compounds: A Hit-Expansion Study and Antimicrobial Evaluation

Future Medicinal Chemistry
2023-10 | Journal article
DOI: 10.4155/fmc-2023-0189
Contributors: Marek Kerda; Petr Šlechta; Ondrej Jand'ourek; Klara Konečná; Paulina Hatoková; Pavla Paterová; Jan Zitko
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Correction: Juhás et al. Improving Antimicrobial Activity and Physico-Chemical Properties by Isosteric Replacement of 2-Aminothiazole with 2-Aminooxazole. Pharmaceuticals 2022, 15, 580

Pharmaceuticals
2023-03-02 | Journal article
DOI: 10.3390/ph16030384
Contributors: Martin Juhás; Andrea Bachtíková; Daria Elżbieta Nawrot; Paulína Hatoková; Vinod Sukanth Kumar Pallabothula; Adéla Diepoltová; Ondřej Janďourek; Pavel Bárta; Klára Konečná; Pavla Paterová et al.
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Improving the Antimicrobial Activity of Old Antibacterial Drug Mafenide: Schiff Bases and Their Bioactivity Targeting Resistant Pathogens

Future Medicinal Chemistry
2023-02 | Journal article
DOI: 10.4155/fmc-2022-0259
Contributors: Martin Krátký; Klára Konečná; Adéla Šimková; Ondřej Janďourek; Jana Maixnerová; Jiřina Stolaříková; Marcela Vejsová; Barbora Voxová; František Trejtnar; Jarmila Vinšová
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Design, Synthesis and Antimicrobial Evaluation of New N-(1-Hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-6-yl)(hetero)aryl-2-carboxamides as Potential Inhibitors of Mycobacterial Leucyl-tRNA Synthetase

International Journal of Molecular Sciences
2023-02-02 | Journal article
DOI: 10.3390/ijms24032951
Contributors: Petr Šlechta; Adam Anthony Needle; Ondřej Jand’ourek; Pavla Paterová; Klára Konečná; Pavel Bárta; Jiří Kuneš; Vladimír Kubíček; Martin Doležal; Marta Kučerová-Chlupáčová
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Design, Synthesis, and Biological Evaluation of New Benzoxaborole Derivatives as Potential Antimycobacterial Agents

2022-11-01 | Conference paper
DOI: 10.3390/ECMC2022-13454
Contributors: Petr Šlechta; Ondřej Jand’ourek; Klára Konečná; Pavla Paterová; Pavel Bárta; Vladimír Kubíček; Martin Doležal; Marta Kučerová-Chlupáčová
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Adenosine-Mimicking Derivatives of 3-Aminopyrazine-2-Carboxamide: Towards Inhibitors of Prolyl-tRNA Synthetase with Antimycobacterial Activity

Biomolecules
2022-10-26 | Journal article
DOI: 10.3390/biom12111561
Contributors: Vinod Sukanth Kumar Pallabothula; Marek Kerda; Martin Juhás; Ondřej Janďourek; Klára Konečná; Pavel Bárta; Pavla Paterová; Jan Zitko
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Alkaloids of Dicranostigma franchetianum (Papaveraceae) and Berberine Derivatives as a New Class of Antimycobacterial Agents

Biomolecules
2022-06-17 | Journal article
DOI: 10.3390/biom12060844
Contributors: Viriyanata Wijaya; Ondřej Janďourek; Jana Křoustková; Kateřina Hradiská-Breiterová; Jan Korábečný; Kateřina Sobolová; Eliška Kohelová; Anna Hošťálková; Klára Konečná; Marcela Šafratová et al.
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Improving Antimicrobial Activity and Physico-Chemical Properties by Isosteric Replacement of 2-Aminothiazole with 2-Aminooxazole

Pharmaceuticals
2022-05-06 | Journal article
DOI: 10.3390/ph15050580
Contributors: Martin Juhás; Andrea Bachtíková; Daria Elżbieta Nawrot; Paulína Hatoková; Vinod Sukanth Kumar Pallabothula; Adéla Diepoltová; Ondřej Janďourek; Pavel Bárta; Klára Konečná; Pavla Paterová et al.
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The Impact of Cultivation Media on the In Vitro Biofilm Biomass Production of Candida spp.

Current Microbiology
2021 | Journal article
DOI: 10.1007/s00284-021-02452-6
EID:

2-s2.0-85103238518

Part of ISSN: 14320991 03438651
Contributors: Konečná, K.; Němečková, I.; Diepoltová, A.; Vejsová, M.; Janďourek, O.
Source: Self-asserted source
Ondřej Janďourek via Scopus - Elsevier

Novel Aminoguanidine Hydrazone Analogues: From Potential Antimicrobial Agents to Potent Cholinesterase Inhibitors

Pharmaceuticals
2021-11 | Journal article | Author
DOI: 10.3390/ph14121229
Contributors: Martin Kratky; Šárka Štěpánková; Klára Konečná; Katarina Svrckova; Jana Maixnerová; Markéta Švarcová; Ondřej Janďourek; František Trejtnar; Jarmila Vinšová
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Multidisciplinary Digital Publishing Institute
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Sulfonamide-salicylaldehyde Imines Active Against methicillin- and trimethoprim/sulfonamide-resistant Staphylococci

Future Medicinal Chemistry
2021-11 | Journal article
DOI: 10.4155/fmc-2021-0169
Contributors: Martin Krátký; Klára Konečná; Jiří Janoušek; Ondřej Janďourek; Jana Maixnerová; Sára Kalivodová; František Trejtnar; Jarmila Vinšová
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Semisynthetic Derivatives of Selected Amaryllidaceae Alkaloids as a New Class of Antimycobacterial Agents

Molecules
2021-10 | Journal article | Author
DOI: 10.3390/molecules26196023
Contributors: Negar Maafi; Abdullah Al Mamun, PhD.; Ondřej Janďourek; Jana Maříková; Kateřina Breiterová; Adéla Diepoltová; Klára Konečná; Anna Hostalkova; Daniela Hulcová; Jiří Kuneš et al.
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Multidisciplinary Digital Publishing Institute
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Synthesis, Biological Evaluation, and In Silico Modeling of N-Substituted Quinoxaline-2-Carboxamides

Pharmaceuticals
2021-08-04 | Journal article
DOI: 10.3390/ph14080768
Contributors: Ghada Bouz; Sarah Bouz; Ondřej Janďourek; Klára Konečná; Pavel Bárta; Jarmila Vinšová; Martin Doležal; Jan Zitko
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Study of the impact of cultivation conditions and peg surface modification on the in vitro biofilm formation of Staphylococcus aureus and Staphylococcus epidermidis in a system analogous to the Calgary biofilm device

Journal of Medical Microbiology
2021-05-28 | Journal article
DOI: 10.1099/jmm.0.001371
Contributors: Adéla Diepoltová; Klára Konečná; Ondřej Janďourek; Petr Nachtigal
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N‐pyridinylbenzamides: an isosteric approach towards new antimycobacterial compounds

Chemical Biology & Drug Design
2021-03 | Journal article
DOI: 10.1111/cbdd.13804
Contributors: Daria Nawrot; Eliška Suchánková; Ondřej Janďourek; Klára Konečná; Pavel Bárta; Martin Doležal; Jan Zitko
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5-Alkylamino-<i>N</i>-phenylpyrazine-2-carboxamides: Design, Preparation, and Antimycobacterial Evaluation

Molecules
2020-03 | Journal article | Author
DOI: 10.3390/molecules25071561
Contributors: Weronika Ambrożkiewicz; Marta Kučerová-Chlupáčová; Ondřej Janďourek; Klára Konečná; Pavla Paterová; Pavel Barta; Jarmila Vinšová; Martin Dolezal; Jan Zitko
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Multidisciplinary Digital Publishing Institute
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<em>N</em>-Pyrazinoyl Substituted Amino Acids as Potential Antimycobacterial Agents—The Synthesis and Biological Evaluation of Enantiomers

Molecules
2020-03 | Journal article | Author
DOI: 10.3390/molecules25071518
Contributors: Martin Juhás; Lucie Kučerová; Ondřej Horáček; Ondřej Janďourek; Vladimír Kubíček; Klára Konečná; Radim Kučera; Pavel Barta; Jiří Janoušek; Pavla Paterová et al.
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A comparative analysis of protein virulence factors released via extracellular vesicles in two Candida albicans strains cultivated in a nutrient-limited medium

Microbial Pathogenesis
2019 | Journal article
DOI: 10.1016/j.micpath.2019.103666
EID:

2-s2.0-85070760687
Contributors: Konečná, K.; Klimentová, J.; Benada, O.; Němečková, I.; Janďourek, O.; Jílek, P.; Vejsová, M.
Source: Self-asserted source
Ondřej Janďourek via Scopus - Elsevier

Phenolic N-monosubstituted carbamates: Antitubercular and toxicity evaluation of multi-targeting compounds

European Journal of Medicinal Chemistry
2019 | Journal article
DOI: 10.1016/j.ejmech.2019.111578
EID:

2-s2.0-85070191479
Contributors: Krátký, M.; Janďourek, O.; Baranyai, Z.; Novotná, E.; Stolaříková, J.; Bősze, S.; Vinšová, J.
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Ondřej Janďourek via Scopus - Elsevier

Substituted N-(Pyrazin-2-yl)benzenesulfonamides; Synthesis, Anti-Infective Evaluation, Cytotoxicity, and In Silico Studies

Molecules
2019-12-29 | Journal article
DOI: 10.3390/molecules25010138
Contributors: Ghada Bouz; Martin Juhás; Lluis Pausas Otero; Cristina Paredes de la Red; Ondřej Janďourek; Klára Konečná; Pavla Paterová; Vladimír Kubíček; Jiří Janoušek; Martin Doležal et al.
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4-Aminobenzoic Acid Derivatives: Converting Folate Precursor to Antimicrobial and Cytotoxic Agents

Biomolecules
2019-12-19 | Journal article
DOI: 10.3390/biom10010009
Contributors: Martin Krátký; Klára Konečná; Jiří Janoušek; Michaela Brablíková; Ondřej Janďourek; František Trejtnar; Jiřina Stolaříková; Jarmila Vinšová
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Development of 3,5-Dinitrophenyl-Containing 1,2,4-Triazoles and Their Trifluoromethyl Analogues as Highly Efficient Antitubercular Agents Inhibiting Decaprenylphosphoryl-β-d-ribofuranose 2′-Oxidase

Journal of Medicinal Chemistry
2019-08-22 | Journal article
DOI: 10.1021/acs.jmedchem.9b00912
Part of ISSN: 0022-2623
Part of ISSN: 1520-4804
Source: Self-asserted source
Ondřej Janďourek
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Derivatives of 3-Aminopyrazine-2-carboxamides: Synthesis, Antimicrobial Evaluation, and in Vitro Cytotoxicity

Molecules
2019-03 | Journal article | Author
DOI: 10.3390/molecules24071212
Contributors: Ghada Bouz; Lucia Semelková; Ondřej Janďourek; Klára Konečná; Pavla Paterová; Lucie Navrátilová; Vladimír Kubíček; Jiří Kuneš; Martin Dolezal; Jan Zitko
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Multidisciplinary Digital Publishing Institute
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Design, synthesis and antimycobacterial activity of hybrid molecules combining pyrazinamide with a 4-phenylthiazol-2-amine scaffold

MedChemComm
2018 | Journal article
DOI: 10.1039/C8MD00056E
Contributors: Jan Zitko; Ondřej Jand'ourek; Pavla Paterová; Lucie Navrátilová; Jiří Kuneš; Jarmila Vinšová; Martin Doležal
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Design, Synthesis and Evaluation of <i>N</i>-pyrazinylbenzamides as Potential Antimycobacterial Agents

Molecules
2018-09 | Journal article | Author
DOI: 10.3390/molecules23092390
Contributors: Jan Zitko; Alžběta Mindlová; Ondřej Valášek; Ondřej Janďourek; Pavla Paterová; Jiří Janoušek; Klára Konečná; Martin Dolezal
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Multidisciplinary Digital Publishing Institute
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3-substituted N-benzylpyrazine-2-carboxamide derivatives: Synthesis, antimycobacterial and antibacterial evaluation

Molecules
2017 | Journal article
DOI: 10.3390/molecules22030495
EID:

2-s2.0-85016258836
Contributors: Semelková, L.; Jand'ourek, O.; Konečná, K.; Paterová, P.; Navrátilová, L.; Trejtnar, F.; Kubíček, V.; Kuneš, J.; Doležal, M.; Zitko, J. et al.
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Ondřej Janďourek via Scopus - Elsevier
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Design, synthesis, antimycobacterial evaluation, and in silico studies of 3-(phenylcarbamoyl)-pyrazine-2-carboxylic acids

Molecules
2017 | Journal article
DOI: 10.3390/molecules22091491
EID:

2-s2.0-85029660516
Contributors: Semelková, L.; Janošcová, P.; Fernandes, C.; Bouz, G.; Jand’Ourek, O.; Konečná, K.; Paterová, P.; Navrátilová, L.; Kuneš, J.; Doležal, M. et al.
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Ondřej Janďourek via Scopus - Elsevier
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Synthesis of Novel Pyrazinamide Derivatives Based on 3-Chloropyrazine-2-carboxamide and Their Antimicrobial Evaluation

Molecules
2017 | Journal article
DOI: 10.3390/molecules22020223
WOSUID:

WOS:000395552400037
Contributors: Jandourek, Ondrej; Tauchman, Marek; Paterova, Pavla; Konecna, Klara; Navratilova, Lucie; Kubicek, Vladimir; Holas, Ondrej; Zitko, Jan; Dolezal, Martin
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Ondřej Janďourek via ResearcherID
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Ureidopyrazine derivatives: Synthesis and biological evaluation as Anti-infectives and abiotic elicitors

Molecules
2017 | Journal article
DOI: 10.3390/molecules22101797
EID:

2-s2.0-85032885669
Contributors: Bouz, G.; Juhás, M.; Niklová, P.; Jand’ourek, O.; Paterová, P.; Ek, J.J.; Tůmová, L.; Kovalíková, Z.; Kastner, P.; Dole al, M. et al.
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Ondřej Janďourek via Scopus - Elsevier
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Novel Halogenated Pyrazine-Based Chalcones as Potential Antimicrobial Drugs

Molecules
2016 | Journal article
DOI: 10.3390/molecules21111421
WOSUID:

WOS:000389918200005
Contributors: Kucerova-Chlupacova, Marta; Vyskovska-Tyllova, Veronika; Richterova-Finkova, Lenka; Kunes, Jiri; Buchta, Vladimir; Vejsova, Marcela; Paterova, Pavla; Semelkova, Lucia; Jandourek, Ondrej; Opletalova, Veronika
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Ondřej Janďourek via ResearcherID
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Alkylamino derivatives of N-benzylpyrazine-2-carboxamide: synthesis and antimycobacterial evaluation

Medchemcomm
2015 | Journal article
DOI: 10.1039/c5md00178a
WOSUID:

WOS:000357786200012
Contributors: Servusova-Vanaskova, Barbora; Jandourek, Ondrej; Paterova, Pavla; Kordulakova, Jana; Plevakova, Magdalena; Kubicek, Vladimir; Kucera, Radim; Garaj, Vladimir; Naesens, Lieve; Kunes, Jiri et al.
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Ondřej Janďourek via ResearcherID
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Microwave-Assisted Synthesis of Pyrazinamide Derivatives: The Coupling Reaction of 3-Chloropyrazine-2-Carboxamide and Ring-Substituted Anilines

Current Organic Synthesis
2015 | Journal article
WOSUID:

WOS:000350751700009
Contributors: Jandourek, Ondrej; Dolezal, Martin; Kunes, Jiri
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Ondřej Janďourek via ResearcherID
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ANTIMYCOBACTERIAL EVALUATION OF NEW PYRAZINAMIDE ANALOGUES

Basic &amp; Clinical Pharmacology &amp; Toxicology
2014 | Journal article
WOSUID:

WOS:000356300901032
Contributors: Dolezal, M.; Zitko, J.; Jandourek, O.; Servusova, B.; Trejtnar, F.
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Ondřej Janďourek via ResearcherID
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N-Substituted 5-Amino-6-methylpyrazine-2,3-dicarbonitriles: Microwave-Assisted Synthesis and Biological Properties

Molecules
2014 | Journal article
DOI: 10.3390/molecules19010651
WOSUID:

WOS:000334420300040
Contributors: Jandourek, Ondrej; Dolezal, Martin; Paterova, Pavla; Kubicek, Vladimir; Pesko, Matus; Kunes, Jiri; Coffey, Aidan; Guo, Jiahui; Kralova, Katarina
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Ondřej Janďourek via ResearcherID
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New Potentially Active Pyrazinamide Derivatives Synthesized Under Microwave Conditions

Molecules
2014 | Journal article
DOI: 10.3390/molecules19079318
WOSUID:

WOS:000340036200039
Contributors: Jandourek, Ondrej; Dolezal, Martin; Kunes, Jiri; Kubicek, Vladimir; Paterova, Pavla; Pesko, Matus; Buchta, Vladimir; Kralova, Katarina; Zitko, Jan
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Ondřej Janďourek via ResearcherID
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