Personal information

Keywords

Nanomedicine and drug delivery, In-vitro and in-vivo Pharmacological evaluation, Bio-nanotechnology, Molecular diagnostics, Recombinant protein

Countries

India

Biography

I am a SERB-National Postdoctoral Fellow at ICAR-NRCE, Hisar. I did my bachelor’s in Pharmacy and master’s in Medical Biotechnology with the first rank in the University (Gold Medalist-Master Degree). I have been awarded by the prestigious fellowship ‘INSPIRE’ by the Department of Science and Technology, Ministry of Science and Technology, Govt of India, for full-time PhD study.
My research interests include synthesis and evaluation of nanoformulations, drug delivery, in-vitro and in-vivo pharmacological evaluations, nanotoxicology, molecular biology, disease detection and diagnosis.

Activities

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Employment (3)

National Research Centre on Equines: Hisar, Haryana, IN

2022-04-01 to present | Principal Investigator (Parasitology )
Employment
Source: Self-asserted source
Ruma Rani; Ruma Saharan

National Research Centre on Equines: Hisar, Haryana, IN

2019-04-01 to 2022-03-31 | CSIR-PostDoctoral Research Associate (Parasitology Lab)
Employment
Source: Self-asserted source
Ruma Rani; Ruma Saharan

National Research Centre on Equines: Hissar, Haryana, IN

2018-04-04 to 2019-03-31 | Senior Research Fellow (National Fellow Lab)
Employment
Source: Self-asserted source
Ruma Rani; Ruma Saharan

Education and qualifications (3)

Guru Jambheshwar University of Science and Technology: Hisar, Haryana, IN

2012-02-27 to 2018-03-09 | PhD (Department of Bio & Nano Technology)
Qualification
Source: Self-asserted source
Ruma Rani; Ruma Saharan

Maharshi Dayanand University Rohtak: Rohtak, Haryana, IN

2008-07 to 2010-08 | MSc Medical Biotechnology (Centre for Biotechnology)
Education
Source: Self-asserted source
Ruma Rani; Ruma Saharan

Maharshi Dayanand University Rohtak: Rohtak, Haryana, IN

2003 to 2007 | B. Pharmacy (SBMNIPR&S)
Education
Source: Self-asserted source
Ruma Rani; Ruma Saharan

Funding (3)

Development of recombinant antibody-based nano-diagnostic lateral flow assay for rapid detection of Trypanosoma evansi infection at Point-of-Care

2022-04 to 2024-03 | Award
Science and Engineering Research Board (SERB) (New Delhi, IN)
Source: Self-asserted source
Ruma Rani; Ruma Saharan

Identification and evaluation of target-specific novel drug molecules against Trypanosoma evansi infection using nanotechnology approach

2019-04 to 2022-03 | Salary award
Council of Scientific and Industrial Research, India (New Delhi, IN)
Source: Self-asserted source
Ruma Rani; Ruma Saharan

Preparation and evaluation of nanoformulations of some bioactive compounds for the treatment of diabetes

2012-02 to 2017-02 | Award
Department of Science and Technology, Ministry of Science and Technology, India (New Delhi, IN)
Source: Self-asserted source
Ruma Rani; Ruma Saharan

Works (38)

Biosensor-Based Diagnosis of Infectious Diseases

Biotechnological Advances in Agriculture, Healthcare, Environment and Industry
2024-11 | Book chapter
Contributors: Ruma Rani; Ruma Saharan
Source: Self-asserted source
Ruma Rani; Ruma Saharan

Polyhydroxyalkanoate: A greener Approach towards Environmental Sustainability

Biotechnological Advances in Agriculture, Healthcare, Environment and Industry
2024-11 | Book chapter
Contributors: Ruma Rani; Ruma Saharan
Source: Self-asserted source
Ruma Rani; Ruma Saharan

Green Essence of Plant Resources Capped Zinc Oxide Nanoparticles: Renewable Distinctions, Size‐Shape‐Modulated Physicochemical Diversity and Emerging Biomedical‐Environmental Usefulness

Particle & Particle Systems Characterization
2024-11-15 | Journal article
DOI: 10.1002/ppsc.202400145
Part of ISSN: 0934-0866
Part of ISSN: 1521-4117
Contributors: Parth Malik; Ruma Rani; Sabina Khan; Donald Fernandes; Tapan Kumar Mukherjee
Source: Self-asserted source
Ruma Rani; Ruma Saharan

Study of mRNA expression of thirteen genes of Trypanosoma evansi in response to diminazene aceturate and isometamidium chloride

The Indian Journal of Animal Sciences
2024-10-08 | Journal article
DOI: 10.56093/ijans.v94i10.153120
Part of ISSN: 2394-3327
Part of ISSN: 0367-8318
Contributors: SNEHIL GUPTA; SUKHDEEP VOHRA; KHUSHBOO SETHI; RUMA RANI; SURBHI GUPTA; RAJENDER KUMAR; SANJAY KUMAR
Source: Self-asserted source
Ruma Rani; Ruma Saharan

Chitosan-Zinc-Ligated Hydroxychloroquine: Molecular Docking, Synthesis, Characterization, and Trypanocidal Activity against Trypanosoma evansi

Polymers
2024-09-30 | Journal article
DOI: 10.3390/polym16192777
Contributors: Anju Manuja; Ruma Rani; Nisha Devi; Monika Sihag; Swati Rani; Minakshi Prasad; Rajender Kumar; Tarun Bhattacharya; Balvinder Kumar
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Gliadin Encapsulated Procyanidolic Oligomers Nanoformulation: Aggrandized Antimicrobial, Antioxidant as Well as Anticancer Potential Makes it an Effective Therapeutic Modality for Lung Carcinoma

Indian Journal of Microbiology
2024-08-29 | Journal article
DOI: 10.1007/s12088-024-01380-w
Part of ISSN: 0046-8991
Part of ISSN: 0973-7715
Contributors: Sant Lal; Monika Kataria; Ruma Rani; Neeraj Dilbaghi
Source: Self-asserted source
Ruma Rani; Ruma Saharan

Recent progress on gold nanoparticle biosensors monitored water quality: Insights on diversified contaminants and functionalization paradigms

Micro and Nano Engineering
2024-06 | Journal article
DOI: 10.1016/j.mne.2024.100261
Part of ISSN: 2590-0072
Contributors: Parth Malik; Ruma Rani; Rachna Gupta; Rakesh Kumar Ameta; Tapan Kumar Mukherjee
Source: Self-asserted source
Ruma Rani; Ruma Saharan

Recent progress on nanoemulsions mediated pesticides delivery: Insights for agricultural sustainability

Plant Nano Biology
2024-05 | Journal article
DOI: 10.1016/j.plana.2024.100073
Part of ISSN: 2773-1111
Contributors: Rachna Gupta; Parth Malik; Ruma Rani; Raghu Solanki; Rakesh Kumar Ameta; Vibhuti Malik; Tapan Kumar Mukherjee
Source: Self-asserted source
Ruma Rani; Ruma Saharan

Understanding the feasibility of chemotherapeutic and immunotherapeutic targets against non-small cell lung cancers: an update of resistant responses and recent combinatorial therapies

Exploration of Targeted Anti-tumor Therapy
2023-10-10 | Journal article
DOI: 10.37349/etat.2023.00171
Contributors: Parth Malik; Ruma Rani; Raghu Solanki; Vishal Haribhai Patel; Tapan Kumar Mukherjee
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Intracellular ROS production and apoptotic effect of quinoline and isoquinoline alkaloids on the growth of Trypanosoma evansi

Acta Tropica
2023-09 | Journal article
DOI: 10.1016/j.actatropica.2023.106980
Part of ISSN: 0001-706X
Contributors: Ruma Rani; Khushboo Sethi; Snehil Gupta; Nitin Virmani; Sanjay Kumar; RAJENDER KUMAR
Source: Self-asserted source
Ruma Rani; Ruma Saharan

In vitro and in vivo evaluation of efficacy of berberine chloride: Phyto-alternative approach against Trypanosoma evansi infection

Molecular and Biochemical Parasitology
2023-06 | Journal article
DOI: 10.1016/j.molbiopara.2023.111562
Part of ISSN: 0166-6851
Contributors: Snehil Gupta; Sukhdeep Vohra; Khushboo Sethi; Ruma Rani; Surbhi Gupta; Sanjay Kumar; RAJENDER KUMAR
Source: Self-asserted source
Ruma Rani; Ruma Saharan

Polyhydroxybutyrate (PHB) in nanoparticulate form improves physical and biological performance of scaffolds

International Journal of Biological Macromolecules
2023-05 | Journal article
DOI: 10.1016/j.ijbiomac.2023.123875
Part of ISSN: 0141-8130
Contributors: Sunena Dhania; Manju Bernela; Ruma Rani; Minakshi Parsad; Rajender Kumar; Rajesh Thakur
Source: Self-asserted source
Ruma Rani; Ruma Saharan

Recent Advances in Mesoporous Silica Nanoparticle-Mediated Drug Delivery for Breast Cancer Treatment

Pharmaceutics
2023-01-09 | Journal article
DOI: 10.3390/pharmaceutics15010227
Contributors: Ruma Rani; Parth Malik; Sunena Dhania; Tapan Kumar Mukherjee
Source: check_circle
Crossref

Natural naphthoquinones and their derivatives as potential drug molecules against trypanosome parasites

Chemical Biology & Drug Design
2022-12 | Journal article
DOI: 10.1111/cbdd.14122
Contributors: Ruma Rani; Khushboo Sethi; Sanjay Kumar; Rajender S. Varma; Rajender Kumar
Source: check_circle
Crossref

Mechanism of Action and Implication of Naphthoquinone as Potent Anti-trypanosomal Drugs

Current Topics in Medicinal Chemistry
2022-10 | Journal article
DOI: 10.2174/1568026622666220912101332
Contributors: Ruma Rani; Khushboo Sethi; Snehil Gupta; Rajender S. Varma; Rajender Kumar
Source: check_circle
Crossref

In vitro and in vivo evaluation of kinase and protease inhibitors against Trypanosoma evansi

Veterinary Research Communications
2022-06-25 | Journal article
DOI: 10.1007/s11259-022-09964-x
Part of ISSN: 0165-7380
Part of ISSN: 1573-7446
Contributors: Ruma Rani; Ruma Saharan
Source: Self-asserted source
Ruma Rani; Ruma Saharan
grade
Preferred source (of 2)‎

Scaffolds the backbone of tissue engineering: Advancements in use of polyhydroxyalkanoates (PHA)

International Journal of Biological Macromolecules
2022-05 | Journal article
DOI: 10.1016/j.ijbiomac.2022.03.030
Part of ISSN: 0141-8130
Contributors: Ruma Rani; Ruma Saharan
Source: Self-asserted source
Ruma Rani; Ruma Saharan

Development of Multiwalled Carbon Nanotube-Based Immunobiosensor for the Detection of Bluetongue Virus

Journal of Nanoscience and Nanotechnology
2021-06-01 | Journal article
DOI: 10.1166/jnn.2021.19000
Part of ISSN: 1533-4880
Contributors: Ruma Rani; Ruma Saharan
Source: Self-asserted source
Ruma Rani; Ruma Saharan

Naphthoquinone derivatives exhibit apoptosis-like effect and anti-trypanosomal activity against Trypanosoma evansi

Veterinary Parasitology
2021-01 | Journal article
Source: Self-asserted source
Ruma Rani; Ruma Saharan

Nanofertilizers Applications and Future Prospects

Nanotechnology Principles and Applications (pp.289-332)Publisher: Jenny Stanford Publishing
2020-11 | Book chapter
Source: Self-asserted source
Ruma Rani; Ruma Saharan

Nanotechnology enabled the enhancement of antitrypanosomal activity of piperine against Trypanosoma evansi

Experimental Parasitology
2020-10 | Journal article
Source: Self-asserted source
Ruma Rani; Ruma Saharan

Drug-induced reactive oxygen species--mediated inhibitory effect on growth of Trypanosoma evansi in axenic culture system

Parasitology Research
2020-07 | Journal article
Source: Self-asserted source
Ruma Rani; Ruma Saharan

Bioengineered Polymer/Composites as Advanced Biological Detection of Sorbitol: An Application in Healthcare Sector

Current Topics in Medicinal Chemistry
2020-03 | Journal article
Source: Self-asserted source
Ruma Rani; Ruma Saharan

Nanomaterials and Their Applications in Bioimaging

Plant Nanobionics, Volume 2, Approaches in Nanoparticles, Biosynthesis, and Toxicity
2019-10 | Book chapter
Source: Self-asserted source
Ruma Rani; Ruma Saharan

Antidiabetic activity enhancement in streptozotocin + nicotinamide–induced diabetic rats through combinational polymeric nanoformulation</p>

International Journal of Nanomedicine
2019-06 | Journal article
DOI: 10.2147/ijn.s205319
Part of ISSN: 1178-2013
Source: Self-asserted source
Ruma Rani; Ruma Saharan

Potentiation of nootropic activity of EGCG loaded nanosuspension by piperine in swiss male albino mice

Future Journal of Pharmaceutical Sciences
2018-12 | Journal article
DOI: 10.1016/j.fjps.2018.10.005
Part of ISSN: 2314-7245
Source: Self-asserted source
Ruma Rani; Ruma Saharan

Improvement of antihyperglycemic activity of nano-thymoquinone in rat model of type-2 diabetes

Chemico-Biological Interactions
2018-11 | Journal article
DOI: 10.1016/j.cbi.2018.02.006
Part of ISSN: 0009-2797
Source: Self-asserted source
Ruma Rani; Ruma Saharan

An update on Equine Piroplasmosis: A potential threat to Zoonosis

INDiAN FARmER
2018-10 | Magazine article
Source: Self-asserted source
Ruma Rani; Ruma Saharan

Pregnancy Diagnosis in bovines

INDiAN FARmER
2018-10 | Magazine article
Source: Self-asserted source
Ruma Rani; Ruma Saharan

Conjugation of epigallocatechin gallate and piperine into a zein nanocarrier: implication on antioxidant and anticancer potential

Advances in Natural Sciences: Nanoscience and Nanotechnology
2018-08-14 | Journal article
DOI: 10.1088/2043-6254/aad5c1
Part of ISSN: 2043-6262
Source: Self-asserted source
Ruma Rani; Ruma Saharan

Carbon nanotubes: a novel material for multifaceted applications in human healthcare

Chemical Society Reviews
2017 | Journal article
DOI: 10.1039/c6cs00517a
Part of ISSN: 0306-0012
Part of ISSN: 1460-4744
Source: Self-asserted source
Ruma Rani; Ruma Saharan

Chitosan-Gellan Gum Bipolymeric Nanohydrogels—a Potential Nanocarrier for the Delivery of Epigallocatechin Gallate

BioNanoScience
2017-09 | Journal article
DOI: 10.1007/s12668-017-0416-0
Part of ISSN: 2191-1630
Part of ISSN: 2191-1649
Source: Self-asserted source
Ruma Rani; Ruma Saharan

Evaluation of anti-diabetic activity of glycyrrhizin-loaded nanoparticles in nicotinamide-streptozotocin-induced diabetic rats

European Journal of Pharmaceutical Sciences
2017-08 | Journal article
DOI: 10.1016/j.ejps.2017.05.068
Part of ISSN: 0928-0987
Source: Self-asserted source
Ruma Rani; Ruma Saharan

Ketoconazole encapsulated in chitosan-gellan gum nanocomplexes exhibits prolonged antifungal activity

International Journal of Biological Macromolecules
2016-12 | Journal article
ISSN: 0141-8130
Source: Self-asserted source
Ruma Rani; Ruma Saharan

Optimization and evaluation of bioactive drug-loaded polymeric nanoparticles for drug delivery

International Journal of Biological Macromolecules
2015-07 | Journal article
DOI: 10.1016/j.ijbiomac.2015.03.070
Part of ISSN: 0141-8130
Source: Self-asserted source
Ruma Rani; Ruma Saharan

Novel Approaches for Enhancement of Drug Bioavailability

Reviews in Advanced Sciences and Engineering
2013-06-01 | Journal article
DOI: 10.1166/rase.2013.1038
Part of ISSN: 2157-9121
Source: Self-asserted source
Ruma Rani; Ruma Saharan

Nanotechnology as Emerging Tool for Enhancing Solubility of Poorly Water-Soluble Drugs

BioNanoScience
2012-12 | Journal article
DOI: 10.1007/s12668-012-0060-7
Part of ISSN: 2191-1630
Part of ISSN: 2191-1649
Source: Self-asserted source
Ruma Rani; Ruma Saharan

Hansch analysis of anti-inflammatory and analgesic activities of substituted 1-alkyl/aryl-3-ethoxy carbonyl-5-hydroxy-2-methyl indoles

Acta Pharmaceutica Sciencia
2011 | Journal article
Part of ISSN: ISSN: 2636-8552
Source: Self-asserted source
Ruma Rani; Ruma Saharan
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