Personal information

Fabry disease, Nephrology, treatment, gene therapy

Activities

Employment (2)

Dalhousie University: Halifax, NS, CA

1990-07-01 to present | Professor of Medicine (Medicine)
Employment
Source: Self-asserted source
Michael L West

University of Saskatchewan College of Medicine: Saskatoon, SK, CA

1986-07 to 1990-06 | Assistant professor (Medicine)
Employment
Source: Self-asserted source
Michael L West

Education and qualifications (9)

American College of Physicians: Philadelphia, PA, US

1990 to present | Fellow FACP
Qualification
Source: Self-asserted source
Michael L West

American Board of Internal Medicine: Philadelphia, PA, US

1986 to present | Diplomat
Qualification
Source: Self-asserted source
Michael L West

Royal College of Physicians and Surgeons of Canada: Ottawa, ON, CA

1985 to present | Certificate of Special Competence in Nephrology
Qualification
Source: Self-asserted source
Michael L West

Royal College of Physicians and Surgeons of Canada: Ottawa, ON, CA

1984 to present | Fellow (Internal Medicine Certification) FRCPC
Qualification
Source: Self-asserted source
Michael L West

University of Toronto: Toronto, ON, CA

1983-07 to 1986-06 | Nephrology Fellowship (St Michael's Hospital)
Education
Source: Self-asserted source
Michael L West

Dalhousie University Faculty of Medicine: Halifax, NS, CA

1980-07 to 1983-06 | Internal Medicine residency (Medicine)
Education
Source: Self-asserted source
Michael L West

Dalhousie University Faculty of Medicine: Halifax, NS, CA

1979-07 to 1980-06 | Rotating Internship (Post Graduate Education)
Education
Source: Self-asserted source
Michael L West

Queen's University: Kingston, ON, CA

1975-09 to 1979-05 | MD
Education
Source: Self-asserted source
Michael L West

Queen's University: Kingston, ON, CA

1971-09 to 1975-05 | BSc Hons
Education
Source: Self-asserted source
Michael L West

Professional activities (4)

American Society of Nephrology: Washington, DC, US

1986 to present | regular
Membership
Source: Self-asserted source
Michael L West

Canadian Society of Nephrology: Montreal, Quebec, CA

1984 to present | regular
Membership
Source: Self-asserted source
Michael L West

Canadian Society of Nephrology: Montreal, Quebec, CA

1997 to 1998 | President
Service
Source: Self-asserted source
Michael L West

International Society of Nephrology: Cranford, NJ, US

1987 | regular
Membership
Source: Self-asserted source
Michael L West

Works (50 of 79)

Items per page:
Page 1 of 2

Fabry nephropathy: a treatable cause of chronic kidney disease

Rare Disease and Orphan Drugs Journal
2024-07-11 | Journal article
Contributors: Michael L. West; Laurette Geldenhuys; Daniel G. Bichet
Source: check_circle
Crossref

Renoprotective Effect of Agalsidase Alfa: A Long-Term Follow-Up of Patients with Fabry Disease

Journal of Clinical Medicine
2022-08-17 | Journal article
Contributors: Markus Cybulla; Kathleen Nicholls; Sandro Feriozzi; Aleš Linhart; Joan Torras; Bojan Vujkovac; Jaco Botha; Christina Anagnostopoulou; Michael L. West
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Independent Registries Are Cost-Effective Tools to Provide Mandatory Postauthorization Surveillance for Orphan Medicinal Products

Value in Health
2021 | Journal article
EID:

2-s2.0-85096532321

Part of ISSN: 15244733 10983015
Contributors: Sirrs, S.M.; Arthus, M.-F.; Bichet, D.G.; Rockman-Greenberg, C.; LeMoine, K.; Morel, C.F.; Lachmann, R.; Lynd, L.D.; Wasim, S.; West, M.L. et al.
Source: Self-asserted source
Michael L West via Scopus - Elsevier

Lentivirus-mediated gene therapy for Fabry disease

Nature Communications
2021 | Journal article
EID:

2-s2.0-85101751131

Part of ISSN: 20411723
Contributors: Khan, A.; Barber, D.L.; Huang, J.; Rupar, C.A.; Rip, J.W.; Auray-Blais, C.; Boutin, M.; O’Hoski, P.; Gargulak, K.; McKillop, W.M. et al.
Source: Self-asserted source
Michael L West via Scopus - Elsevier

Standardising clinical outcomes measures for adult clinical trials in Fabry disease: A global Delphi consensus

Molecular Genetics and Metabolism
2021 | Journal article
EID:

2-s2.0-85101623383

Part of ISSN: 10967206 10967192
Contributors: Moreno-Martinez, D.; Aguiar, P.; Auray-Blais, C.; Beck, M.; Bichet, D.G.; Burlina, A.; Cole, D.; Elliott, P.; Feldt-Rasmussen, U.; Feriozzi, S. et al.
Source: Self-asserted source
Michael L West via Scopus - Elsevier

The Safety of Agalsidase Alfa Enzyme Replacement Therapy in Canadian Patients with Fabry Disease Following Implementation of a Bioreactor Process

Drugs in R&D
2021-12-20 | Journal article
Contributors: Aneal Khan; Sandra M. Sirrs; Daniel G. Bichet; Chantal F. Morel; Adina Tocoian; Lan Lan; Michael L. West
Source: check_circle
Crossref

Gene therapy for Fabry disease: Progress, challenges, and outlooks on gene-editing

Molecular Genetics and Metabolism
2021-07 | Journal article
Part of ISSN: 1096-7192
Source: Self-asserted source
Michael L West

Cardiomyopathy and kidney function in agalsidase beta-treated female Fabry patients: a pre-treatment vs. post-treatment analysis

ESC Heart Failure
2020 | Journal article
EID:

2-s2.0-85085713734

Part of ISSN: 20555822
Contributors: Wanner, C.; Feldt-Rasmussen, U.; Jovanovic, A.; Linhart, A.; Yang, M.; Ponce, E.; Brand, E.; Germain, D.P.; Hughes, D.A.; Jefferies, J.L. et al.
Source: Self-asserted source
Michael L West via Scopus - Elsevier

Early indicators of disease progression in Fabry disease that may indicate the need for disease-specific treatment initiation: Findings from the opinion-based PREDICT-FD modified Delphi consensus initiative

BMJ Open
2020 | Journal article
EID:

2-s2.0-85092752427

Part of ISSN: 20446055
Contributors: Hughes, D.A.; Aguiar, P.; Deegan, P.B.; Ezgu, F.; Frustaci, A.; Lidove, O.; Linhart, A.; Lubanda, J.-C.; Moon, J.C.; Nicholls, K. et al.
Source: Self-asserted source
Michael L West via Scopus - Elsevier

Renal-Limited Antiglomerular Basement Membrane Disease Related To Alemtuzumab: A Case Report

Canadian Journal of Kidney Health and Disease
2020 | Journal article
EID:

2-s2.0-85092687019

Part of ISSN: 20543581
Contributors: Harrigan, A.M.; West, M.L.; Geldenhuys, L.; Poyah, P.
Source: Self-asserted source
Michael L West via Scopus - Elsevier

Therapeutic challenges in two adolescent male patients with Fabry disease and high antibody titres

Molecular Genetics and Metabolism Reports
2020 | Journal article
EID:

2-s2.0-85087059701

Part of ISSN: 22144269
Contributors: Mhanni, A.A.; Auray-Blais, C.; Boutin, M.; Johnston, A.; LeMoine, K.; Patterson, J.; Aerts, J.M.F.G.; West, M.L.; Rockman-Greenberg, C.
Source: Self-asserted source
Michael L West via Scopus - Elsevier

Use of denosumab to treat refractory hypercalcemia in a peritoneal dialysis patient with immobilization and tertiary hyperparathyroidism

Peritoneal Dialysis International
2020 | Journal article
EID:

2-s2.0-85077541821

Part of ISSN: 17184304 08968608
Contributors: Pratt, R.M.; West, M.L.; Tennankore, K.K.
Source: Self-asserted source
Michael L West via Scopus - Elsevier

Cardio- Renal Outcomes With Long- Term Agalsidase Alfa Enzyme Replacement Therapy: A 10- Year Fabry Outcome Survey (FOS) Analysis

Drug Design, Development and Therapy
2019-10 | Journal article
Source: Self-asserted source
Michael L West
grade
Preferred source (of 3)‎

Agalsidase alfa versus agalsidase beta for the treatment of Fabry disease: an international cohort study

Journal of medical genetics
2018 | Journal article
EID:

2-s2.0-85050636118

Part of ISSN: 14686244
Source: Self-asserted source
Michael L West
grade
Preferred source (of 2)‎

Elevated inflammatory plasma biomarkers in patients with fabry disease: A critical link to heart failure with preserved ejection fraction

Journal of the American Heart Association
2018 | Journal article
EID:

2-s2.0-85056885563

Part of ISSN: 20479980
Source: Self-asserted source
Michael L West
grade
Preferred source (of 2)‎

Long-term outcomes with agalsidase alfa enzyme replacement therapy: Analysis using deconstructed composite events

Molecular Genetics and Metabolism Reports
2018 | Journal article
EID:

2-s2.0-85033383240

Part of ISSN: 22144269
Contributors: Beck, M.; Hughes, D.; Kampmann, C.; Pintos-Morell, G.; Ramaswami, U.; West, M.L.; Giugliani, R.
Source: Self-asserted source
Michael L West via Scopus - Elsevier

Lentivector Iterations and Pre-Clinical Scale-Up/Toxicity Testing: Targeting Mobilized CD34<sup>+</sup> Cells for Correction of Fabry Disease

Molecular Therapy - Methods and Clinical Development
2017 | Journal article
EID:

2-s2.0-85020540097

Part of ISSN: 23290501
Source: Self-asserted source
Michael L West
grade
Preferred source (of 2)‎

Screening, diagnosis, and management of patients with Fabry disease: conclusions from a "Kidney Disease: Improving Global Outcomes" (KDIGO) Controversies Conference

Kidney international
2017 | Journal article
EID:

2-s2.0-85008208873

Part of ISSN: 15231755
Contributors: Schiffmann, R.; Hughes, D.A.; Linthorst, G.E.; Ortiz, A.; Svarstad, E.; Warnock, D.G.; West, M.L.; Wanner, C.
Source: Self-asserted source
Michael L West via Scopus - Elsevier

Tetrahydrobiopterin deficiency in the pathogenesis of Fabry disease

Human Molecular Genetics
2017 | Journal article
EID:

2-s2.0-85019074582

Part of ISSN: 14602083 09646906
Contributors: Shen, J.-S.; Arning, E.; West, M.L.; Day, T.S.; Chen, S.; Meng, X.-L.; Forni, S.; McNeill, N.; Goker-Alpan, O.; Wang, X. et al.
Source: Self-asserted source
Michael L West via Scopus - Elsevier

Prevalence of Fabry Disease and Outcomes in Young Canadian Patients With Cryptogenic Ischemic Cerebrovascular Events

Stroke
2017-07 | Journal article
Part of ISSN: 0039-2499
Part of ISSN: 1524-4628
Source: Self-asserted source
Michael L West

A 15-year perspective of the fabry outcome survey

Journal of Inborn Errors of Metabolism and Screening
2016 | Journal article
EID:

2-s2.0-85043562576

Part of ISSN: 23264594 23264098
Source: Self-asserted source
Michael L West
grade
Preferred source (of 2)‎

Chronic kidney disease and an uncertain diagnosis of Fabry disease: Approach to a correct diagnosis

Molecular Genetics and Metabolism
2015 | Journal article
EID:

2-s2.0-84921672014

Part of ISSN: 10967206 10967192
Contributors: van der Tol, L.; Svarstad, E.; Ortiz, A.; Tøndel, C.; Oliveira, J.P.; Vogt, L.; Waldek, S.; Hughes, D.A.; Lachmann, R.H.; Terryn, W. et al.
Source: Self-asserted source
Michael L West via Scopus - Elsevier

Gender-specific plasma proteomic biomarkers in patients with Anderson-Fabry disease

European Journal of Heart Failure
2015 | Journal article
EID:

2-s2.0-84924432854

Part of ISSN: 18790844 13889842
Contributors: Hollander, Z.; Dai, D.L.Y.; Putko, B.N.; Yogasundaram, H.; Wilson-Mcmanus, J.E.; Thompson, R.B.; Khan, A.; West, M.L.; McManus, B.M.; Oudit, G.Y.
Source: Self-asserted source
Michael L West via Scopus - Elsevier

Long-term effectiveness of agalsidase alfa enzyme replacement in Fabry disease: A Fabry Outcome Survey analysis

Molecular Genetics and Metabolism Reports
2015 | Journal article
EID:

2-s2.0-84930011520

Part of ISSN: 22144269
Contributors: Beck, M.; Hughes, D.; Kampmann, C.; Larroque, S.; Mehta, A.; Pintos-Morell, G.; Ramaswami, U.; West, M.; Wijatyk, A.; Giugliani, R.
Source: Self-asserted source
Michael L West via Scopus - Elsevier

Percutaneous native renal biopsy adequacy: A successful interdepartmental quality improvement activity

Canadian Journal of Kidney Health and Disease
2015 | Journal article
EID:

2-s2.0-84998879926

Part of ISSN: 20543581
Contributors: Geldenhuys, L.; Nicholson, P.; Sinha, N.; Dini, A.; Doucette, S.; Alfaadhel, T.; Keough, V.; West, M.
Source: Self-asserted source
Michael L West via Scopus - Elsevier

Mosaicism of podocyte involvement is related to podocyte injury in females with Fabry disease

PLoS ONE
2014 | Journal article
EID:

2-s2.0-84911424960

Part of ISSN: 19326203
Contributors: Mauer, M.; Glynn, E.; Svarstad, E.; Tøndel, C.; Gubler, M.-C.; West, M.; Sokolovskiy, A.; Whitley, C.; Najafian, B.
Source: Self-asserted source
Michael L West via Scopus - Elsevier

Outcomes of patients treated through the Canadian Fabry disease initiative

Molecular Genetics and Metabolism
2014 | Journal article
EID:

2-s2.0-84897573302

Part of ISSN: 10967206 10967192
Source: Self-asserted source
Michael L West
grade
Preferred source (of 2)‎

Uncertain diagnosis of fabry disease in patients with neuropathic pain, angiokeratoma or cornea verticillata: Consensus on the approach to diagnosis and follow-up

JIMD Reports
2014 | Book chapter
EID:

2-s2.0-84930639571

Part of ISSN: 21928312 21928304
Source: Self-asserted source
Michael L West
grade
Preferred source (of 2)‎

Uncertain diagnosis of Fabry disease: Consensus recommendation on diagnosis in adults with left ventricular hypertrophy and genetic variants of unknown significance

International Journal of Cardiology
2014 | Journal article
EID:

2-s2.0-84913529020

Part of ISSN: 18741754 01675273
Contributors: Smid, B.E.; Van Der Tol, L.; Cecchi, F.; Elliott, P.M.; Hughes, D.A.; Linthorst, G.E.; Timmermans, J.; Weidemann, F.; West, M.L.; Biegstraaten, M. et al.
Source: Self-asserted source
Michael L West via Scopus - Elsevier

Urinary biomarker investigation in children with Fabry disease using tandem mass spectrometry

Clinica Chimica Acta
2014 | Journal article
EID:

2-s2.0-84907180947

Part of ISSN: 18733492 00098981
Contributors: Auray-Blais, C.; Blais, C.-M.; Ramaswami, U.; Boutin, M.; Germain, D.P.; Dyack, S.; Bodamer, O.; Pintos-Morell, G.; Clarke, J.T.R.; Bichet, D.G. et al.
Source: Self-asserted source
Michael L West via Scopus - Elsevier

Changes in plasma and urine globotriaosylceramide levels do not predict Fabry disease progression over 1 year of agalsidase alfa

Genetics in Medicine
2013 | Journal article
EID:

2-s2.0-84890084688

Part of ISSN: 10983600 15300366
Contributors: Schiffmann, R.; Ries, M.; Blankenship, D.; Nicholls, K.; Mehta, A.; Clarke, J.T.R.; Steiner, R.D.; Beck, M.; Barshop, B.A.; Rhead, W. et al.
Source: Self-asserted source
Michael L West via Scopus - Elsevier

Kidney transplantation and enzyme replacement therapy in patients with Fabry disease

Journal of Nephrology
2013 | Journal article
EID:

2-s2.0-84880089118

Part of ISSN: 11218428 17246059
Contributors: Cybulla, M.; Kurschat, C.; West, M.; Nicholls, K.; Torras, J.; Sunder-Plassmann, G.; Feriozzi, S.
Source: Self-asserted source
Michael L West via Scopus - Elsevier

Recommendations on reintroduction of agalsidase beta for patients with fabry disease in Europe, following a period of shortage

JIMD Reports
2013 | Book chapter
EID:

2-s2.0-85029602462

Part of ISSN: 21928312 21928304
Source: Self-asserted source
Michael L West
grade
Preferred source (of 2)‎

Fabry international prognostic index: A predictive severity score for Anderson-Fabry disease

Journal of Medical Genetics
2012 | Journal article
EID:

2-s2.0-84860312738

Part of ISSN: 00222593 14686244
Contributors: Hughes, D.A.; Malmenäs, M.; Deegan, P.B.; Elliott, P.M.; Ginsberg, L.; Hajioff, D.; Ioannidis, A.S.; Orteu, C.H.; Ramaswami, U.; West, M. et al.
Source: Self-asserted source
Michael L West via Scopus - Elsevier

The effectiveness of long-term agalsidase alfa therapy in the treatment of fabry nephropathy

Clinical Journal of the American Society of Nephrology
2012 | Journal article
EID:

2-s2.0-84857082168

Part of ISSN: 15559041 1555905X
Contributors: Feriozzi, S.; Torras, J.; Cybulla, M.; Nicholls, K.; Sunder-Plassmann, G.; West, M.
Source: Self-asserted source
Michael L West via Scopus - Elsevier

Cardiovascular events in patients with Fabry disease: Natural history data from the Fabry Registry

Journal of the American College of Cardiology
2011 | Journal article
EID:

2-s2.0-79951983786

Part of ISSN: 07351097
Contributors: Patel, M.R.; Cecchi, F.; Cizmarik, M.; Kantola, I.; Linhart, A.; Nicholls, K.; Strotmann, J.; Tallaj, J.; Tran, T.C.; West, M.L. et al.
Source: Self-asserted source
Michael L West via Scopus - Elsevier

Tranexamic Acid Treatment of Life-Threatening Hematuria in Polycystic Kidney Disease

International Journal of Nephrology
2011 | Journal article
Part of ISSN: 2090-214X
Part of ISSN: 2090-2158
Source: Self-asserted source
Michael L West

A validated disease severity scoring system for Fabry disease

Molecular Genetics and Metabolism
2010 | Journal article
EID:

2-s2.0-76549116109

Part of ISSN: 10967192 10967206
Contributors: Giannini, E.H.; Mehta, A.B.; Hilz, M.J.; Beck, M.; Bichet, D.G.; Brady, R.O.; West, M.; Germain, D.P.; Wanner, C.; Waldek, S. et al.
Source: Self-asserted source
Michael L West via Scopus - Elsevier

ARBs/ACE inhibitors in Fabry disease: Rescue or peril?

International Journal of Clinical Pharmacology and Therapeutics
2010 | Journal article
EID:

2-s2.0-77949471863

Part of ISSN: 09461965
Contributors: West, M.L.
Source: Self-asserted source
Michael L West via Scopus - Elsevier

Baseline characteristics of patients enrolled in the Canadian Fabry Disease Initiative

Molecular Genetics and Metabolism
2010 | Journal article
EID:

2-s2.0-77649338096

Part of ISSN: 10967192 10967206
Contributors: Sirrs, S.; Clarke, J.T.R.; Bichet, D.G.; Casey, R.; Lemoine, K.; Flowerdew, G.; Sinasac, D.S.; West, M.L.
Source: Self-asserted source
Michael L West via Scopus - Elsevier

Effects of enzyme replacement therapy in Fabry disease - A comprehensive review of the medical literature

Genetics in Medicine
2010 | Journal article
EID:

2-s2.0-78649634506

Part of ISSN: 10983600
Contributors: Lidove, O.; West, M.L.; Pintos-Morell, G.; Reisin, R.; Nicholls, K.; Figuera, L.E.; Parini, R.; Carvalho, L.R.; Kampmann, C.; Pastores, G.M. et al.
Source: Self-asserted source
Michael L West via Scopus - Elsevier

Enzyme replacement therapy and fabry nephropathy

Clinical Journal of the American Society of Nephrology
2010 | Journal article
EID:

2-s2.0-77749320320

Part of ISSN: 15559041 1555905X
Source: Self-asserted source
Michael L West
grade
Preferred source (of 2)‎

How well does urinary lyso-Gb<inf>3</inf> function as a biomarker in Fabry disease?

Clinica Chimica Acta
2010 | Journal article
EID:

2-s2.0-77957756430

Part of ISSN: 00098981
Source: Self-asserted source
Michael L West
grade
Preferred source (of 2)‎

Renal manifestations of fabry disease

Fabry Disease
2010 | Book chapter
EID:

2-s2.0-78650732092

Contributors: Warnock, D.G.; Valbuena, C.; West, M.; Oliveira, J.P.
Source: Self-asserted source
Michael L West via Scopus - Elsevier

Scoring system for renal pathology in Fabry disease: Report of the International Study Group of Fabry Nephropathy (ISGFN)

Nephrology Dialysis Transplantation
2010 | Journal article
EID:

2-s2.0-77954321307

Part of ISSN: 14602385 09310509
Contributors: Fogo, A.B.; Bostad, L.; Svarstad, E.; Cook, W.J.; Moll, S.; Barbey, F.; Geldenhuys, L.; West, M.; Ferluga, D.; Vujkovac, B. et al.
Source: Self-asserted source
Michael L West via Scopus - Elsevier

The Canadian Fabry Disease Initiative: A randomized controlled trial of agalsidase therapy in Fabry nephropathy

International Journal of Clinical Pharmacology and Therapeutics
2010 | Journal article
EID:

2-s2.0-77949454519

Part of ISSN: 09461965
Contributors: West, M.; Flowerdew, G.; Lemoine, K.; Bichet, D.; Casey, R.; Clarke, J.; Sirrs, S.; Auray-Blais, C.
Source: Self-asserted source
Michael L West via Scopus - Elsevier

Therapeutic goals in the treatment of Fabry disease

Genetics in Medicine
2010 | Journal article
EID:

2-s2.0-78649632339

Part of ISSN: 10983600
Contributors: Mehta, A.; West, M.L.; Pintos-Morell, G.; Reisin, R.; Nicholls, K.; Figuera, L.E.; Parini, R.; Carvalho, L.R.; Kampmann, C.; Pastores, G.M. et al.
Source: Self-asserted source
Michael L West via Scopus - Elsevier

Agalsidase alfa and kidney dysfunction in Fabry disease

Journal of the American Society of Nephrology
2009 | Journal article
EID:

2-s2.0-65649096032

Part of ISSN: 10466673 15333450
Contributors: West, M.; Nicholls, K.; Mehta, A.; Clarke, J.T.R.; Steiner, R.; Beck, M.; Barshop, B.A.; Rhead, W.; Mensah, R.; Ries, M. et al.
Source: Self-asserted source
Michael L West via Scopus - Elsevier

Agalsidase alfa slows the decline in renal function in patients with fabry disease

American Journal of Nephrology
2009 | Journal article
EID:

2-s2.0-54949106603

Part of ISSN: 02508095
Source: Self-asserted source
Michael L West
grade
Preferred source (of 2)‎

Urinary globotriaosylceramide excretion correlates with the genotype in children and adults with Fabry disease

Molecular Genetics and Metabolism
2008 | Journal article
EID:

2-s2.0-38849109999

Part of ISSN: 10967192 10967206
Contributors: Auray-Blais, C.; Cyr, D.; Ntwari, A.; West, M.L.; Cox-Brinkman, J.; Bichet, D.G.; Germain, D.P.; Laframboise, R.; Melançon, S.B.; Stockley, T. et al.
Source: Self-asserted source
Michael L West via Scopus - Elsevier
Items per page:
Page 1 of 2

Peer review (14 reviews for 10 publications/grants)

Review activity for BMC nephrology (2)
Review activity for Clinical and experimental nephrology. (1)
Review activity for European journal of internal medicine. (1)
Review activity for International urology and nephrology : (2)
Review activity for Journal of medical genetics (1)
Review activity for Kidney medicine. (1)
Review activity for Molecular genetics and metabolism. (1)
Review activity for Orphanet journal of rare diseases. (3)
Review activity for PloS one. (1)
Review activity for UK Research and Innovation (1)