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Works (13)

Accumulation of T-cell-suppressive PD-L1<sup>high</sup>extracellular vesicles is associated with GvHD and might impact GvL efficacy

Journal for ImmunoTherapy of Cancer
2023-03 | Journal article
DOI: 10.1136/jitc-2022-006362
Part of ISSN: 2051-1426
Contributors: Rebecca Baur; Franziska Karl; Romy Böttcher-Loschinski; Andrej Stoll; Simon Völkl; Andreas Gießl; Cindy Flamann; Heiko Bruns; Ursula Schlötzer-Schrehardt; Martin Böttcher et al.
Source: Self-asserted source
Romy Böttcher-Loschinski

Oxidative DNA damage in reconstituting T cells is associated with relapse and inferior survival after allo-SCT

Blood
2023-03-30 | Journal article
DOI: 10.1182/blood.2022017267
Part of ISSN: 0006-4971
Part of ISSN: 1528-0020
Contributors: F. Karl; C. Liang; R. Böttcher-Loschinski; Andrej Stoll; C. Flamann; S. Richter; Christopher Lischer; S. Völkl; B. Jacobs; Martin Böttcher et al.
Source: Self-asserted source
Romy Böttcher-Loschinski

TIGIT signaling and its influence on T cell metabolism and immune cell function in the tumor microenvironment

Frontiers in Oncology
2023-02-17 | Review
DOI: 10.3389/fonc.2023.1060112
Part of ISSN: 2234-943X
Contributors: Nouria Jantz-Naeem; Romy Böttcher-Loschinski; Katrin Borucki; Marisa Mitchell-Flack; Martin Böttcher; Burkhart Schraven; Dimitrios Mougiakakos; Sascha Kahlfuss
Source: Self-asserted source
Romy Böttcher-Loschinski

Lipotoxicity as a Barrier for T Cell-Based Therapies

Biomolecules
2022-08-25 | Review
DOI: 10.3390/biom12091182
Part of ISSN: 2218-273X
Contributors: Romy Böttcher-Loschinski; Judit Rial Saborido; Martin Böttcher; Sascha Kahlfuß; Dimitrios Mougiakakos
Source: Self-asserted source
Romy Böttcher-Loschinski

CLL-Derived Extracellular Vesicles Impair T-Cell Activation and Foster T-Cell Exhaustion via Multiple Immunological Checkpoints

Cells
2022-07-12 | Journal article
DOI: 10.3390/cells11142176
Part of ISSN: 2073-4409
Contributors: Martin Böttcher; Romy Böttcher-Loschinski; Sascha Kahlfuß; Michael Aigner; Andreas Gießl; Andreas Mackensen; Ursula Schlötzer-Schrehardt; Thomas Tüting; Heiko Bruns; Dimitrios Mougiakakos
Source: Self-asserted source
Romy Böttcher-Loschinski

IL‐3 is essential for ICOS‐L stabilization on mast cells, and sustains the IL‐33‐induced RORγt<sup>+</sup> T<sub>reg</sub> generation via enhanced IL‐6 induction

Immunology
2021-05 | Journal article
DOI: 10.1111/imm.13305
Part of ISSN: 0019-2805
Part of ISSN: 1365-2567
Contributors: Sebastian Drube; Sylvia Müller; Franziska Weber; Philine Wegner; Romy Böttcher‐Loschinski; Matthias Gaestel; Andreas Hutloff; Thomas Kamradt; Nico Andreas
Source: Self-asserted source
Romy Böttcher-Loschinski

Impact of Nrf2 expression in reconstituting T-cells of allogeneic hematopoietic stem cell transplanted patients

Leukemia
2021-03 | Journal article
DOI: 10.1038/s41375-020-0956-0
Part of ISSN: 0887-6924
Part of ISSN: 1476-5551
Contributors: Franziska Karl; Andrej Stoll; Romy Böttcher-Loschinski; Martin Böttcher; Rebecca Baur; Benedikt Jacobs; Simon Völkl; Regina Jitschin; Wolf Rösler; Andreas Mackensen et al.
Source: Self-asserted source
Romy Böttcher-Loschinski

Palmitoylated Proteins on AML-Derived Extracellular Vesicles Promote Myeloid-Derived Suppressor Cell Differentiation via TLR2/Akt/mTOR Signaling

Cancer Research
2020-09-01 | Journal article
DOI: 10.1158/0008-5472.can-20-0024
Part of ISSN: 0008-5472
Part of ISSN: 1538-7445
Contributors: Sehmus Tohumeken; Rebecca Baur; Martin Böttcher; Andrej Stoll; Romy Loschinski; Konstantinos Panagiotidis; Martina Braun; Domenica Saul; Simon Völkl; Andreas S. Baur et al.
Source: Self-asserted source
Romy Böttcher-Loschinski

Inflammation-induced glycolytic switch controls suppressivity of mesenchymal stem cells via STAT1 glycosylation.

Leukemia
2019-01-24 | Journal article
DOI: 10.1038/s41375-018-0376-6
PMID: 30679801
Source: Self-asserted source
Romy Böttcher-Loschinski

IL-21 modulates memory and exhaustion phenotype of T-cells in a fatty acid oxidation-dependent manner.

Oncotarget
2018-02-07 | Journal article
DOI: 10.18632/oncotarget.24442
PMID: 29568345
PMC: PMC5862566
Source: Self-asserted source
Romy Böttcher-Loschinski

Mesenchymal Stromal Cells Disrupt mTOR-Signaling and Aerobic Glycolysis During T-Cell Activation.

Stem cells (Dayton, Ohio)
2015-11-17 | Journal article
DOI: 10.1002/stem.2234
PMID: 26485560
Source: Self-asserted source
Romy Böttcher-Loschinski

TAK1 and IKK2, novel mediators of SCF-induced signaling and potential targets for c-Kit-driven diseases.

Oncotarget
2015-10-01 | Journal article
DOI: 10.18632/oncotarget.5008
PMID: 26353931
PMC: PMC4745695
Source: Self-asserted source
Romy Böttcher-Loschinski

Subthreshold IKK activation modulates the effector functions of primary mast cells and allows specific targeting of transformed mast cells.

Oncotarget
2015-03-01 | Journal article
DOI: 10.18632/oncotarget.3022
PMID: 25749030
PMC: PMC4467154
Source: Self-asserted source
Romy Böttcher-Loschinski
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